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1. 发明申请

US20100145956A1 PSEUDO-ANCHOR TEXT EXTRACTION 有权
标题翻译： PSEUDO-ANCHOR文本提取
公开(公告)号：US20100145956A1
公开(公告)日：2010-06-10
申请号：US12697056
申请日：2010-01-29
申请人： Shuming Shi , Zaiqing Nie , Ji-Rong Wen , Mingjie Zhu , Fei Xing
发明人： Shuming Shi , Zaiqing Nie , Ji-Rong Wen , Mingjie Zhu , Fei Xing
IPC分类号： G06F17/30
CPC分类号： G06F17/30616 , G06F17/30864 , Y10S707/99932
摘要： A search method uses pseudo-anchor text associated with search objects to improve search performance. The pseudo-anchor text may be extracted in combination with an identifier of the search objects (such as a pseudo-URL) from a digital corpus such as a collection of documents. Pseudo-anchor texts for each object are preferably extracted from candidate anchor blocks using a machine learning based approach. The pseudo-anchor texts are made available for searching and used to help rank the objects in a search result to improve search performance. The method may be used in vertical search of objects such as published articles, products and images that lack explicit URLs and anchor text information.
摘要翻译：搜索方法使用与搜索对象相关联的伪锚文本来改善搜索性能。伪锚文本可以与来自诸如文档集合的数字语料库的搜索对象（诸如伪URL）的标识符组合提取。优选地，使用基于机器学习的方法从候选锚块中提取每个对象的伪锚文本。伪锚文本可用于搜索，并用于帮助对搜索结果中的对象进行排名以提高搜索性能。该方法可以用于垂直搜索诸如已发表的文章，产品和缺乏明确的URL和锚文本信息的图像的对象。

2. 发明授权

US08073838B2 Pseudo-anchor text extraction 有权
标题翻译：伪锚文本提取
公开(公告)号：US08073838B2
公开(公告)日：2011-12-06
申请号：US12697056
申请日：2010-01-29
申请人： Shuming Shi , Ji-Rong Wen , Mingjie Zhu , Fei Xing , Zaiqing Nie
发明人： Shuming Shi , Ji-Rong Wen , Mingjie Zhu , Fei Xing , Zaiqing Nie
IPC分类号： G06F17/30
CPC分类号： G06F17/30616 , G06F17/30864 , Y10S707/99932
摘要： A search method uses pseudo-anchor text associated with search objects to improve search performance. The pseudo-anchor text may be extracted in combination with an identifier of the search objects (such as a pseudo-URL) from a digital corpus such as a collection of documents. Pseudo-anchor texts for each object are preferably extracted from candidate anchor blocks using a machine learning based approach. The pseudo-anchor texts are made available for searching and used to help rank the objects in a search result to improve search performance. The method may be used in vertical search of objects such as published articles, products and images that lack explicit URLs and anchor text information.
摘要翻译：搜索方法使用与搜索对象相关联的伪锚文本来改善搜索性能。伪锚文本可以与来自诸如文档集合的数字语料库的搜索对象（诸如伪URL）的标识符组合提取。优选地，使用基于机器学习的方法从候选锚块中提取每个对象的伪锚文本。伪锚文本可用于搜索，并用于帮助对搜索结果中的对象进行排名以提高搜索性能。该方法可以用于垂直搜索诸如已发表的文章，产品和缺乏明确的URL和锚文本信息的图像的对象。

3. 发明申请

US20080215563A1 Pseudo-Anchor Text Extraction for Vertical Search 失效
标题翻译：用于垂直搜索的伪锚文本提取
公开(公告)号：US20080215563A1
公开(公告)日：2008-09-04
申请号：US11681682
申请日：2007-03-02
申请人： Shuming Shi , Zaiqing Nie , Ji-Rong Wen , Mingjie Zhu , Fei Xing
发明人： Shuming Shi , Zaiqing Nie , Ji-Rong Wen , Mingjie Zhu , Fei Xing
IPC分类号： G06F17/30
CPC分类号： G06F17/30616 , G06F17/30864 , Y10S707/99932
摘要： A search method uses pseudo-anchor text associated with search objects to improve search performance. The pseudo-anchor text may be extracted in combination with an identifier of the search objects (such as a pseudo-URL) from a digital corpus such as a collection of documents. Pseudo-anchor texts for each object are preferably extracted from candidate anchor blocks using a machine learning based approach. The pseudo-anchor texts are made available for searching and used to help ranking the objects in a search result to improve search performance. Method may be used in vertical search of objects such as published articles, products and images that lack explicit URL and anchor text information.
摘要翻译：搜索方法使用与搜索对象相关联的伪锚文本来改善搜索性能。伪锚文本可以与来自诸如文档集合的数字语料库的搜索对象（诸如伪URL）的标识符组合提取。优选地，使用基于机器学习的方法从候选锚块中提取每个对象的伪锚文本。伪锚文本可用于搜索，并用于帮助对搜索结果中的对象进行排名以提高搜索性能。方法可用于垂直搜索诸如已发表的文章，产品和图像之类的对象，缺少明确的URL和锚文本信息。

4. 发明授权

US07657507B2 Pseudo-anchor text extraction for vertical search 失效
标题翻译：用于垂直搜索的伪锚文本提取
公开(公告)号：US07657507B2
公开(公告)日：2010-02-02
申请号：US11681682
申请日：2007-03-02
申请人： Shuming Shi , Zaiqing Nie , Ji-Rong Wen , Mingjie Zhu , Fei Xing
发明人： Shuming Shi , Zaiqing Nie , Ji-Rong Wen , Mingjie Zhu , Fei Xing
IPC分类号： G06F17/30
CPC分类号： G06F17/30616 , G06F17/30864 , Y10S707/99932
摘要： A search method uses pseudo-anchor text associated with search objects to improve search performance. The pseudo-anchor text may be extracted in combination with an identifier of the search objects (such as a pseudo-URL) from a digital corpus such as a collection of documents. Pseudo-anchor texts for each object are preferably extracted from candidate anchor blocks using a machine learning based approach. The pseudo-anchor texts are made available for searching and used to help ranking the objects in a search result to improve search performance. Method may be used in vertical search of objects such as published articles, products and images that lack explicit URL and anchor text information.
摘要翻译：搜索方法使用与搜索对象相关联的伪锚文本来改善搜索性能。伪锚文本可以与来自诸如文档集合的数字语料库的搜索对象（诸如伪URL）的标识符组合提取。优选地，使用基于机器学习的方法从候选锚块中提取每个对象的伪锚文本。伪锚文本可用于搜索，并用于帮助对搜索结果中的对象进行排名以提高搜索性能。方法可用于垂直搜索诸如已发表的文章，产品和图像之类的对象，缺少明确的URL和锚文本信息。

5. 发明授权

US08785477B2 Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof 有权
标题翻译：六氢吡咯并[3,4-b]吡咯衍生物，其制备方法和药物用途
公开(公告)号：US08785477B2
公开(公告)日：2014-07-22
申请号：US13685454
申请日：2012-11-26
申请人： Peng Lu , Rui Zhang , Wansong Yu , Mingjie Zhu , Yilang Chen
发明人： Peng Lu , Rui Zhang , Wansong Yu , Mingjie Zhu , Yilang Chen
IPC分类号： C07D487/04
CPC分类号： C07D487/04
摘要： Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof are provided. Specifically, dipeptidyl peptidase IV inhibitors presented by following formula (I) are provided. Such compounds can be used for treating or preventing the diseases associated with dipeptidyl peptidase IV, such as diabetes, obesity and hyperlipemia. The compounds presented by formula (I) and pharmaceutically acceptable salts thereof, a method for preparing a pharmaceutical composition thereof and their uses in the manufacture of medicaments for treating or preventing the disease associated with dipeptidyl peptidase IV are provided.
摘要翻译：提供了六氢吡咯并[3,4-b]吡咯衍生物，其制备方法和药物用途。具体地，提供了由下式（I）表示的二肽基肽酶IV抑制剂。这些化合物可用于治疗或预防与二肽基肽酶IV相关的疾病，如糖尿病，肥胖症和高脂血症。提供式（I）化合物及其药学上可接受的盐，其药物组合物的制备方法及其在制备用于治疗或预防与二肽基肽酶IV相关的疾病的药物中的用途。

6. 发明申请

US20130178500A1 HEXAHYDROPYRROLO[3,4-b]PYRROLE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF 有权
标题翻译：十氢吡咯并[3,4-b]吡咯烷酮衍生物，其制备方法及其药物用途
公开(公告)号：US20130178500A1
公开(公告)日：2013-07-11
申请号：US13685454
申请日：2012-11-26
申请人： Peng Lu , Rui Zhang , Wansong Yu , Mingjie Zhu , Yilang Chen
发明人： Peng Lu , Rui Zhang , Wansong Yu , Mingjie Zhu , Yilang Chen
IPC分类号： C07D487/04
CPC分类号： C07D487/04
摘要： Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof are provided. Specifically, dipeptidyl peptidase IV inhibitors presented by following formula (I) are provided. Such compounds can be used for treating or preventing the diseases associated with dipeptidyl peptidase IV, such as diabetes, obesity and hyperlipemia. The compounds presented by formula (I) and pharmaceutically acceptable salts thereof, a method for preparing a pharmaceutical composition thereof and their uses in the manufacture of medicaments for treating or preventing the disease associated with dipeptidyl peptidase IV are provided.
摘要翻译：提供了六氢吡咯并[3,4-b]吡咯衍生物，其制备方法和药物用途。具体地，提供了由下式（I）表示的二肽基肽酶IV抑制剂。这些化合物可用于治疗或预防与二肽基肽酶IV相关的疾病，如糖尿病，肥胖症和高脂血症。提供式（I）化合物及其药学上可接受的盐，其药物组合物的制备方法及其在制备用于治疗或预防与二肽基肽酶IV相关的疾病的药物中的用途。

7. 发明授权

US06420517B1 Process for resin phase separation by plate decantation 有权
标题翻译：通过板倾析进行树脂相分离的方法
公开(公告)号：US06420517B1
公开(公告)日：2002-07-16
申请号：US09778157
申请日：2001-02-06
申请人： Cornelius Adrianus Maria van Gool , Martin Herke Oyevaar , Anthony Warren , Claude Tinney , Mingjie Zhu
发明人： Cornelius Adrianus Maria van Gool , Martin Herke Oyevaar , Anthony Warren , Claude Tinney , Mingjie Zhu
IPC分类号： C08J316
CPC分类号： C08G64/406 , B01D17/0211 , B01D17/0217 , B01D17/045 , B01D17/047
摘要： This invention relates to an economical and efficient process for purifying a reaction mixture obtained in a two-phase interfacial reaction for the preparation of polycarbonate. More particularly, the method of the invention provides for separating the reaction mixture into an organic phase, which includes the desired polycarbonate and undesirable impurities, and an aqueous phase. The organic phase is further purified by using a plate decanter in combination with coalescence and centrifugation.
摘要翻译：本发明涉及用于纯化在用于制备聚碳酸酯的两相界面反应中获得的反应混合物的经济和有效的方法。更具体地，本发明的方法提供将反应混合物分离成有机相，其包括所需的聚碳酸酯和不期望的杂质以及水相。有机相通过使用板式滗析器与聚结和离心结合进一步纯化。

8. 发明申请

US20130052134A1 PEG-PLGA-PLL POLYMER AND METHOD FOR PREPARING AND USING THE SAME AS THE DRUG AND GENE CARRIER 审中-公开
标题翻译： PEG-PLGA-PLL聚合物及其制备和使用其作为药物和基因载体的方法
公开(公告)号：US20130052134A1
公开(公告)日：2013-02-28
申请号：US13518874
申请日：2010-12-28
申请人： Yourong Duan , Peifeng Liu , Ying Sun , Ming Shen , Mingjie Zhu , Yanming Sun , Qi Wang , Zelai He , Liubin Qin , Hui Yu , Xiaoyu Li , Xuelian Qi , Xiaoyan Chen , Qiufen Sun , Bingwu Wang
发明人： Yourong Duan , Peifeng Liu , Ying Sun , Ming Shen , Mingjie Zhu , Yanming Sun , Qi Wang , Zelai He , Liubin Qin , Hui Yu , Xiaoyu Li , Xuelian Qi , Xiaoyan Chen , Qiufen Sun , Bingwu Wang
IPC分类号： A61K47/34 , A61K49/00 , C08G63/91 , A61K9/14 , B82Y5/00
CPC分类号： A61K48/0041 , A61K9/5153 , A61K47/62 , A61K47/6935 , C08G63/664 , C08G63/6852 , C08G63/912 , C08G69/10 , C08G69/44 , C08G2261/126 , C12N15/87
摘要： This invention belongs to the nanotechnology field, and discloses a nano drug delivery system with polyethyleneglycol-poly(lactic-co-glycolic acid)-poly-L-lysine (PEG-PLGA-PLL) polymer as the skeleton. The carrier can have the function of passive targeting through control of the carrier particle size. The polymer skeleton is modified through introducing side chains and specific targeting groups, so as to adjust and improve the carrier performance, and enable the carrier to have the function of active targeting. Such carrier material also has the functions of transporting active substances, tumor treatment and diagnosis, ultrasonic contrast, reversing or reducing drug resistance and so on. It is mainly applied to (1) Targeting preparation of anticancer drugs; (2) preparation to reverse or reduce the drug resistance of the tumor; (3) reagent for tumor diagnosis and contrast; (4) reagent to transfect DNA plasmids; (5) pharmaceutical preparation for cancer gene therapy; (6) reagent used to transfect antisense nucleic acid and siRNA (RNA interference); (7) pharmaceutical preparation used to prepare antisense nucleic acid and siRNA (RNA interference).
摘要翻译：本发明属于纳米技术领域，公开了以聚乙二醇 - 聚（乳酸 - 共 - 乙醇酸） - 聚-L-赖氨酸（PEG-PLGA-PLL）聚合物为骨架的纳米药物输送系统。通过控制载体粒径，载体可以具有被动靶向的功能。通过引入侧链和特异性靶向基来改进聚合物骨架，从而调节和改善载体性能，并使载体具有主动靶向功能。这种载体材料还具有运输活性物质，肿瘤治疗和诊断，超声对比，逆转或降低耐药性等功能。主要适用于（1）抗癌药物的靶向制备; （2）准备逆转或降低肿瘤的耐药性; （3）肿瘤诊断试剂和对比剂; （4）转染DNA质粒的试剂; （5）癌基因治疗药物制剂; （6）用于转染反义核酸和siRNA（RNA干扰）的试剂; （7）用于制备反义核酸和siRNA（RNA干扰）的药物制剂。

9. 发明授权

US06860972B2 Process for detecting the location of a phase interface 有权
标题翻译：用于检测相位接口位置的过程
公开(公告)号：US06860972B2
公开(公告)日：2005-03-01
申请号：US10064164
申请日：2002-06-17
申请人： Karithik Balakrishnan , Danny L. McNeil , Martin Herke Oyevaar , Claude Tinney , Cornelis Adrianus Maria van Gool , Anthony Warren , Xiaolin Wu , Mingjie Zhu
发明人： Karithik Balakrishnan , Danny L. McNeil , Martin Herke Oyevaar , Claude Tinney , Cornelis Adrianus Maria van Gool , Anthony Warren , Xiaolin Wu , Mingjie Zhu
IPC分类号： B01D17/00 , B01D17/02 , B01D21/00 , C08G64/40 , H05F3/00
CPC分类号： C08G64/406 , B01D17/00 , B01D17/0211 , B01D17/0217 , B01D17/045 , B01D17/047 , B01D17/12 , B01D21/00 , B01D21/0039 , B01D21/0042 , B01D21/26 , B01D21/262
摘要： Disclosed herein are processes for detecting the location of an interface between phases. In one embodiment, the process comprises: introducing a reaction mixture into a vessel wherein the reaction mixture is the product of an at least two phase interfacial reaction, and a difference in densities between at least two of the phases is less than or equal to about 1 g/cc, separating the reaction mixture into the phases with an interface located therebetween, measuring electrical inductance of the reaction mixture at different latitudinal locations; and determining the location of the interface.
摘要翻译：这里公开了用于检测相位之间的界面的位置的处理。在一个实施方案中，该方法包括：将反应混合物引入容器中，其中反应混合物是至少两相界面反应的产物，并且至少两相之间的密度差小于或等于约 1g / cc，将反应混合物分离成具有位于其间的界面的相，测量反应混合物在不同纬度位置的电感; 并确定接口的位置。

10. 发明授权

US06369190B1 Extraction of triethylamine in polycarbonate by the use of static mixers 有权
标题翻译：通过使用静态混合器在聚碳酸酯中提取三乙胺
公开(公告)号：US06369190B1
公开(公告)日：2002-04-09
申请号：US09712321
申请日：2000-11-14
申请人： Mingjie Zhu , Allen Wai-Yee Ko
发明人： Mingjie Zhu , Allen Wai-Yee Ko
IPC分类号： C08G6400
CPC分类号： C08G64/406
摘要： This invention relates to a method for purifying a polycarbonate resin solution resulting from an interfacial polymerization process. More particularly, this invention provides for the use of at least one static mixer to facilitate separation of the catalyst used to prepare the polycarbonate from the polycarbonate resin solution.
摘要翻译：本发明涉及由界面聚合方法得到的聚碳酸酯树脂溶液的净化方法。更具体地说，本发明提供使用至少一种静态混合器来促进从聚碳酸酯树脂溶液中分离用于制备聚碳酸酯的催化剂。

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