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1. 发明授权

US08414873B2 Blood vessel stent of amidoglucosan polysaccharide loaded with CD133 antibody and its preparation method 有权
标题翻译：含有CD133抗体的糖胺聚糖多糖血管支架及其制备方法
公开(公告)号：US08414873B2
公开(公告)日：2013-04-09
申请号：US12602976
申请日：2008-10-10
申请人： Shixuan Zhang , Jinghan Sui , Hong Zhao , Dazhi Yang
发明人： Shixuan Zhang , Jinghan Sui , Hong Zhao , Dazhi Yang
IPC分类号： A61K31/74 , A61K9/00 , A61F2/00 , A01N25/00
CPC分类号： A61L31/16 , A61L31/022 , A61L31/10 , A61L2300/256 , A61L2420/06 , C08L5/08
摘要： A blood vessel metal stent coating of amidoglucosan polysaccharide loaded with antibody comprises carrier material composed of chitosan and inartificial degradable acidic amidoglucosan polysaccharide and the effective dose of CD133 antibody loaded in the carrier material. The blood vessel metal stent coating is manufactured with self-assemble method to fix the CD133 antibody in the carrier material of the coating. The coating has good biocompatibility, water retention property, flexibility, flush resistance and bio-stability, and can specifically capture the vascular endothelial progenitor cells in human peripheral blood, and differentiate into vascular endothelial cells. The process would accelerate endothelialization to repair injured vessel caused and prevent restenosis and thrombosis efficiently.
摘要翻译：负载抗体的酰胺葡聚糖多糖的血管金属支架涂层包括由壳聚糖和人造可降解的酸性糖胺聚糖多糖组成的载体材料，并载入载体材料中的有效剂量的CD133抗体。使用自组装方法制造血管金属支架涂层，以将CD133抗体固定在涂层的载体材料中。该涂层具有良好的生物相容性，保水性，柔韧性，冲洗性和生物稳定性，并且可以特异性捕获人外周血中的血管内皮祖细胞，并分化成血管内皮细胞。该过程将加速内皮化修复损伤的血管，并有效预防再狭窄和血栓形成。

2. 发明申请

US20100215712A1 BLOOD VESSEL STENT OF AMIDOGLUCOSAN POLYSACCHARIDE LOADED WITH CD133 ANTIBODY AND ITS PREPARATION METHOD 有权
标题翻译：用CD133抗体负载的氨基多糖多糖的血管支架及其制备方法
公开(公告)号：US20100215712A1
公开(公告)日：2010-08-26
申请号：US12602976
申请日：2008-10-10
申请人： Shixuan Zhang , Jinghan Sui , Hong Zhao , Dazhi Yang
发明人： Shixuan Zhang , Jinghan Sui , Hong Zhao , Dazhi Yang
IPC分类号： A61K39/395 , A61F2/04 , A61P9/00
CPC分类号： A61L31/16 , A61L31/022 , A61L31/10 , A61L2300/256 , A61L2420/06 , C08L5/08
摘要： A blood vessel metal stent coating of amidoglucosan polysaccharide loaded with antibody comprises carrier material composed of chitosan and inartificial degradable acidic amidoglucosan polysaccharide and the effective dose of CD133 antibody loaded in the carrier material. The blood vessel metal stent coating is manufactured with self-assemble method to fix the CD133 antibody in the carrier material of the coating. The coating has good biocompatibility, water retention property, flexibility, flush resistance and bio-stability, and can specifically capture the vascular endothelial progenitor cells in human peripheral blood, and differentiate into vascular endothelial cells. The process would accelerate endothelialization to repair injured vessel caused and prevent restenosis and thrombosis efficiently.
摘要翻译：负载抗体的酰胺葡聚糖多糖的血管金属支架涂层包括由壳聚糖和人造可降解的酸性糖胺聚糖多糖组成的载体材料，并载入载体材料中的有效剂量的CD133抗体。使用自组装方法制造血管金属支架涂层，以将CD133抗体固定在涂层的载体材料中。该涂层具有良好的生物相容性，保水性，柔韧性，冲洗性和生物稳定性，并且可以特异性捕获人外周血中的血管内皮祖细胞，并分化成血管内皮细胞。该过程将加速内皮化修复损伤的血管，并有效预防再狭窄和血栓形成。

3. 发明申请

US20220093915A1 SILICON MONOXIDE COMPOSITE MATERIAL, METHOD FOR PREPARING SAME, AND LITHIUM ION BATTERY 有权
公开(公告)号：US20220093915A1
公开(公告)日：2022-03-24
申请号：US17120209
申请日：2020-12-13
申请人： Hong Zhao
发明人： Hong Zhao
IPC分类号： H01M4/36 , C23C16/02 , C23C16/26 , H01M10/0525 , H01M4/587 , H01M4/48 , H01M4/04
摘要： A method for preparing a silicon monoxide composite material includes: a first stage: introducing a protective gas into a vapor deposition oven, and pre-heating a silicon monoxide raw material, such that a part of the silicon monoxide raw material is subjected to a disproportionation reaction; a second stage: continuously introducing the protective gas and introducing a carbon source gas, and subjecting the pre-heated silicon monoxide raw material to a chemical vapor deposition to form carbon nanotubes on a surface of silicon monoxide; and a third stage: after a predetermined time period, stopping introducing the carbon source gas, and stopping introducing the protective gas until the vapor deposition oven is cooled to room temperature, to prepare the silicon monoxide composite material. During the preparation process, no extra catalyst needs to be added, a product of the previous disproportionation reaction may act as a catalyst for the growth of the carbon nanotubes.

4. 发明授权

US11237283B2 Visco-pseudo-elastic TTI FWI/RTM formulation and implementation 有权
公开(公告)号：US11237283B2
公开(公告)日：2022-02-01
申请号：US16000960
申请日：2018-06-06
申请人： Praveen Nakshatrala , Anoop A. Mullur , Hong Zhao , Valeriy V. Brytik
发明人： Praveen Nakshatrala , Anoop A. Mullur , Hong Zhao , Valeriy V. Brytik
IPC分类号： G01V1/28 , G01V1/30
摘要： A method, including: obtaining, with a computer, an initial geophysical model; modeling, with a computer, a forward wavefield based on the initial geophysical model with wave equations including a second order z-derivative in a rotated coordinate system that accounts for a tilted transverse isotropic (TTI) medium; modeling, with a computer, an adjoint wavefield with adjoint wave equations including a second order z-derivative in a rotated coordinate system that accounts for a tilted transverse isotropic (TTI) medium, wherein the wave equations and the adjoint wave equations include relaxation terms accounting for anelasticity of earth in an update of a primary variable and an evolution relationship for the relaxation terms; and obtaining, with a computer, a gradient of a cost function based on a combination of a model of the forward wavefield and a model of the adjoint wavefield.

5. 发明授权

US09146624B2 Method for managing screen orientation of a portable electronic device 有权
标题翻译：用于管理便携式电子设备的屏幕方向的方法
公开(公告)号：US09146624B2
公开(公告)日：2015-09-29
申请号：US13368853
申请日：2012-02-08
申请人： Hong Zhao , LieJun Tao , Dean E. Thorson
发明人： Hong Zhao , LieJun Tao , Dean E. Thorson
IPC分类号： G06F3/0346 , G06F3/01 , G06F1/16
CPC分类号： G06F3/0346 , G06F1/1686 , G06F1/1694 , G06F3/012 , G06F3/013 , G06F2200/1614 , G06F2200/1637
摘要： There is described a portable electronic device capable of managing screen orientation. The portable electronic device comprises a display, a motion sensor, an image sensor and a processor. The display provides an image at a first orientation. The motion sensor attempts to detect a rotation of the portable electronic device. The image sensor attempts to detect one or more body features. The processor determines a second orientation of the image at the display based on the rotation detected at the motion sensor and/or the body feature or features detected at the image sensor. The portable electronic device may determine an orientation of the image at the display in response to detecting the rotation at the motion sensor and/or the body feature or features at the image sensor.
摘要翻译：描述了能够管理屏幕取向的便携式电子设备。便携式电子设备包括显示器，运动传感器，图像传感器和处理器。显示器以第一方向提供图像。运动传感器尝试检测便携式电子设备的旋转。图像传感器尝试检测一个或多个身体特征。处理器基于在运动传感器处检测到的旋转和/或在图像传感器处检测到的身体特征或特征来确定图像在显示器处的第二取向。响应于检测到运动传感器处的旋转和/或图像传感器处的身体特征或特征，便携式电子设备可以确定显示器处的图像的取向。

6. 发明授权

US09110519B2 Method for managing screen orientation of a portable electronic device 有权
公开(公告)号：US09110519B2
公开(公告)日：2015-08-18
申请号：US13368853
申请日：2012-02-08
申请人： Hong Zhao , LieJun Tao , Dean E Thorson
发明人： Hong Zhao , LieJun Tao , Dean E Thorson
IPC分类号： G06F3/0346 , G06F3/01 , G06F1/16
摘要： There is described a portable electronic device capable of managing screen orientation. The portable electronic device comprises a display, a motion sensor, an image sensor and a processor. The display provides an image at a first orientation. The motion sensor attempts to detect a rotation of the portable electronic device. The image sensor attempts to detect one or more body features. The processor determines a second orientation of the image at the display based on the rotation detected at the motion sensor and/or the body feature or features detected at the image sensor. The portable electronic device may determine an orientation of the image at the display in response to detecting the rotation at the motion sensor and/or the body feature or features at the image sensor.

7. 发明授权

US08849276B2 Intelligent network selection based on quality of service and applications over different wireless networks 有权
标题翻译：基于不同无线网络的服务质量和应用的智能网络选择
公开(公告)号：US08849276B2
公开(公告)日：2014-09-30
申请号：US12197830
申请日：2008-08-25
申请人： Ann C. Guilford , Mike Verstegen , Hong Zhao
发明人： Ann C. Guilford , Mike Verstegen , Hong Zhao
IPC分类号： H04W4/00 , H04W36/00 , H04W48/18 , H04W28/24 , H04W28/08
CPC分类号： H04W48/18 , H04M15/8038 , H04M2215/34 , H04W28/0247 , H04W28/08 , H04W28/24
摘要： A system and method for selecting a wireless network is disclosed. The method relates to selecting a wireless network from a plurality of wireless networks. A variation of the invention includes selecting a new platform from a plurality of platforms offered by the current service provider according to a service request from the wireless device. The method comprises determining a requested service associated with the wireless device, determining whether one of the plurality of wireless networks can provide the requested service, and, if one of the plurality of wireless networks can provide the requested service, choosing the one wireless network of the plurality of wireless networks. The method further involves using a variety of parameters in determining which wireless network to choose for servicing the requested service from the wireless device. These parameters include quality of services, application supported, or other business factors such as roaming agreements, traffic load and cost of services. The system comprises at least one wireless network node, a wireless device, and a plurality of wireless networks communicating with each other. Either the wireless device or network node may operate to decide based on the services the wireless device user requires on which network the user will receive service from. The network assignment is accomplished to maximize the speed, cost and efficiency of transmission.
摘要翻译：公开了一种用于选择无线网络的系统和方法。该方法涉及从多个无线网络中选择无线网络。本发明的变型包括根据来自无线设备的服务请求从当前服务提供商提供的多个平台中选择新平台。该方法包括确定与无线设备相关联的所请求的服务，确定所述多个无线网络中的一个是否能够提供所请求的服务;以及如果所述多个无线网络中的一个可以提供所请求的服务，则选择所述一个无线网络多个无线网络。该方法还涉及使用各种参数来确定从无线设备为哪个无线网络选择用于服务所请求的服务。这些参数包括服务质量，支持的应用程序或其他业务因素，如漫游协议，流量负载和服务成本。该系统包括彼此通信的至少一个无线网络节点，无线设备和多个无线网络。无线设备或网络节点可以基于无线设备用户在用户将从哪个网络接收服务所需的服务来进行操作。实现网络分配以最大限度地提高传输的速度，成本和效率。

8. 发明授权

US08748573B2 Formulations comprising linaclotide 有权
标题翻译：包含利那洛肽的制剂
公开(公告)号：US08748573B2
公开(公告)日：2014-06-10
申请号：US12851330
申请日：2010-08-05
申请人： Angelika Fretzen , Steven Witowski , Alfredo Grossi , Hong Zhao , Mahendra Dedhiya , Yun Mo
发明人： Angelika Fretzen , Steven Witowski , Alfredo Grossi , Hong Zhao , Mahendra Dedhiya , Yun Mo
IPC分类号： C07K7/08 , C07K7/06
CPC分类号： A61K9/50 , A61K9/1611 , A61K9/1617 , A61K9/1623 , A61K9/205 , A61K9/2054 , A61K9/485 , A61K9/4858 , A61K9/4866 , A61K9/5078 , A61K38/10 , A61K38/12 , A61K47/02 , A61K47/183 , A61K47/36 , B65D81/26 , G01N30/02 , G01N2030/027
摘要： The present invention relates to stable compositions comprising linaclotide, as well as to various methods and processes for the preparation and use of the compositions.
摘要翻译：本发明涉及包含利那洛肽的稳定组合物，以及用于制备和使用组合物的各种方法和方法。

9. 发明申请

US20140073571A9 Treatments for Gastrointestinal Disorders 有权
标题翻译：胃肠道疾病治疗
公开(公告)号：US20140073571A9
公开(公告)日：2014-03-13
申请号：US13579685
申请日：2011-02-17
申请人： Angelika Fretzen , Hong Zhao , Marco Kessler
发明人： Angelika Fretzen , Hong Zhao , Marco Kessler
IPC分类号： C07K7/08 , A61K45/06 , A61K38/10
CPC分类号： C07K7/08 , A61K38/08 , A61K38/10 , A61K45/06 , C07K7/06
摘要： The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein, using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.
摘要翻译：本发明涉及用于治疗胃肠道疾病和病症的肽，组合物和相关方法，包括但不限于肠易激综合征（IBS），胃肠蠕动障碍，功能性胃肠道疾病，胃食管反流病（GERD），十二指肠胃反流，克罗恩氏病疾病，溃疡性结肠炎，炎性肠病，功能性胃灼热，消化不良，内脏痛，胃轻瘫，慢性肠假性梗阻（或结肠假性梗阻），与便秘相关的病症和病症以及其它病症和病症在本文中用肽描述和激活鸟苷酸环化酶C（GC-C）受体的其它试剂。

10. 发明申请

US20140022311A1 THERMAL BUBBLE JETTING MECHANISM, METHOD OF JETTING AND METHOD OF MAKING THE MECHANISM 有权
标题翻译：热泡喷射机构，喷射方法及制造方法
公开(公告)号：US20140022311A1
公开(公告)日：2014-01-23
申请号：US13555901
申请日：2012-07-23
申请人： Kock-Yee Law , Jun Ma , Hong Zhao , Peter M. Gulvin
发明人： Kock-Yee Law , Jun Ma , Hong Zhao , Peter M. Gulvin
IPC分类号： B41J2/05 , B41J2/16
CPC分类号： B41J2/1404 , B41J2/14064 , B41J2/1412
摘要： A thermal bubble jetting device including a substrate. A superoleophobic, textured surface is positioned on the substrate. The textured surface comprises one or more gaps configured for holding a gas. A receptacle is positioned in fluid communication with the textured surface. Both an inlet and nozzle are in fluid communication with the receptacle. The device includes a heater mechanism configured to expand a gas in the one or more gaps so as to sufficiently increase pressure in the receptacle to force liquid through the nozzle.
摘要翻译：一种包括基板的热气泡喷射装置。超疏油，有纹理的表面位于基底上。纹理表面包括被配置用于保持气体的一个或多个间隙。容器定位成与纹理表面流体连通。入口和喷嘴均与容器流体连通。该装置包括加热器机构，其构造成在一个或多个间隙中膨胀气体，以便充分增加容器中的压力以迫使液体通过喷嘴。

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