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1. 发明授权

US5733918A Condensed-Indan derivatives and pharmaceutically acceptable salts thereof 失效
标题翻译：缩合 - 茚满衍生物及其药学上可接受的盐
公开(公告)号：US5733918A
公开(公告)日：1998-03-31
申请号：US578542
申请日：1996-01-19
申请人： Shinji Okazaki , Tetsuji Asao , Motoji Wakida , Keisuke Ishida , Masato Washinosu , Teruhiro Utsugi , Yuji Yamada
发明人： Shinji Okazaki , Tetsuji Asao , Motoji Wakida , Keisuke Ishida , Masato Washinosu , Teruhiro Utsugi , Yuji Yamada
IPC分类号： A61K31/44 , A61K31/473 , A61P35/00 , C07D221/18 , C07D401/12 , C07D491/04 , C07D491/056 , C07D521/00 , A61K31/47 , C07D491/56
CPC分类号： C07D231/12 , C07D221/18 , C07D233/56 , C07D249/08 , C07D401/12 , C07D491/04
摘要： A condensed-indan derivative represented by formula (1) and a pharmaceutically acceptable salt thereof: ##STR1## wherein ring A represents an optionally substituted benzene ring or naphthalene ring, or a benzene ring having a lower alkylenedioxy group, ring B represents an optionally substituted benzene ring or a benzene ring having a lower alkylenedioxy group. Y represents --N.dbd.CR-- or --CR=N--, R represents a --NR.sub.1 R.sub.2 group, an optionally substituted nitrogen-containing heterocyclic group or a --OR.sub.3 group, wherein R.sub.1 and R.sub.2 are the same or different and each is a hydrogen atom; a phenyl group; an optionally substituted nitrogen-containing heterocyclic group; or a lower alkyl group which may be substituted by at least one selected from the group consisting of an optionally substituted amino group, a lower alkoxy group, a phenyl group, a nitrogen-containing heterocyclic group, an amine oxide group substituted by a lower alkyl group or a hydroxyl group(s); R.sub.3 represents a lower alkyl group optionally substituted by a substituted amino group, except when R represents an optionally substituted nitrogen-containing heterocyclic group; ring A and ring B are a benzene ring having no substituent group.
摘要翻译： PCT No.PCT / JP95 / 00944 Sec。 371日期1996年1月19日 102（e）日期1996年1月19日PCT提交1995年5月18日PCT公布。出版物WO95 / 32187 日期：1995年11月30日由式（1）表示的缩合 - 缩水甘油衍生物及其药学上可接受的盐：其中环A表示任选取代的苯环或萘环，或具有低级亚烷基二氧基基团，环B表示任选取代的苯环或具有较低亚烷基二氧基的苯环。 Y表示-N = CR-或-CR = N-，R表示-NR1R2基，任选取代的含氮杂环基或-OR 3基，其中R1和R2相同或不同，各自为氢原子 ; 苯基; 任选取代的含氮杂环基; 或可以被选自任选取代的氨基，低级烷氧基，苯基，含氮杂环基，被低级烷基取代的氧化胺基中的至少一种取代的低级烷基基团或羟基; R3表示任选被取代的氨基取代的低级烷基，除了当R表示任意取代的含氮杂环基时; 环A和环B是没有取代基的苯环。

2. 发明授权

US6028079A Condensed-indan derivatives and pharmaceutically acceptable salts thereof 失效
标题翻译：缩水甘油衍生物及其药学上可接受的盐
公开(公告)号：US6028079A
公开(公告)日：2000-02-22
申请号：US909934
申请日：1997-08-12
申请人： Shinji Okazaki , Tetsuji Asao , Motoji Wakida , Keisuke Ishida , Masato Washinosu , Teruhiro Utsugi , Yuji Yamada
发明人： Shinji Okazaki , Tetsuji Asao , Motoji Wakida , Keisuke Ishida , Masato Washinosu , Teruhiro Utsugi , Yuji Yamada
IPC分类号： A61K31/44 , A61K31/473 , A61P35/00 , C07D221/18 , C07D401/12 , C07D491/04 , C07D491/056 , C07D521/00
CPC分类号： C07D231/12 , C07D221/18 , C07D233/56 , C07D249/08 , C07D401/12 , C07D491/04
摘要： A condensed-indan derivative represented by formula (1) and a pharmaceutically acceptable salt thereof: wherein ring A represents an optionally substituted benzene ring or naphthalene ring, or a benzene ring having a lower alkylenedioxy group, ring B represents an optionally substituted benzene ring or a benzene ring having a lower alkylenedioxy group. Y represents --N.dbd.CR-- or --CR.dbd.N--, R represents a --NR.sub.1 R.sub.2 group, an optionally substituted nitrogen-containing heterocyclic group or a --OR.sub.3 group, wherein R.sub.1 and R.sub.2 are the same or different and each is a hydrogen atom; a phenyl group; an optionally substituted nitrogen-containing heterocyclic group; or a lower alkyl group which may be substituted by at least one selected from the group consisting of an optionally substituted amino group, a lower alkoxy group, a phenyl group, a nitrogen-containing heterocyclic group, an amine oxide group substituted by a lower alkyl group or a hydroxyl group(s); R.sub.3 represents a lower alkyl group optionally substituted by a substituted amino group, except when R represents an optionally substituted nitrogen-containing heterocyclic group; ring A and ring B are a benzene ring having no substituent group.
摘要翻译：由式（1）表示的缩合 - 茚满衍生物及其药学上可接受的盐：其中环A表示任选取代的苯环或萘环，或具有低亚烷基二氧基的苯环，环B表示任选取代的苯环或具有低亚烷基二氧基的苯环。 Y表示-N = CR-或-CR = N-，R表示-NR1R2基，任选取代的含氮杂环基或-OR 3基，其中R1和R2相同或不同，各自为氢原子 ; 苯基; 任选取代的含氮杂环基; 或可以被选自任选取代的氨基，低级烷氧基，苯基，含氮杂环基，被低级烷基取代的氧化胺基中的至少一种取代的低级烷基基团或羟基; R3表示任选被取代的氨基取代的低级烷基，除了当R表示任意取代的含氮杂环基时; 环A和环B是没有取代基的苯环。

3. 发明授权

US5763453A Condensed indan derivatives and salts thereof 失效
标题翻译：稠合茚满衍生物及其盐
公开(公告)号：US5763453A
公开(公告)日：1998-06-09
申请号：US809602
申请日：1997-04-03
申请人： Shinji Okazaki , Tetsuji Asao , Teruhiro Utsugi , Yuji Yamada
发明人： Shinji Okazaki , Tetsuji Asao , Teruhiro Utsugi , Yuji Yamada
IPC分类号： A61K31/47 , A61K31/473 , A61P35/00 , C07D221/18 , C07D401/04 , C07D491/056
CPC分类号： C07D401/04 , C07D221/18
摘要： A condensed indan derivative represented by the formula (1) ##STR1## wherein the ring A is an optionally substituted benzene ring or a benzene ring which has lower alkylenedioxy group(s), the ring B is an optionally substituted benzene ring or a benzene ring which has lower alkylene dioxy group(s), and R is a group --NR.sub.1 R.sub.2, an optionally substituted nitrogen-containing heterocyclic group, a group --OR.sub.3 or a group --SR.sub.4 (wherein R.sub.1 and R.sub.2 are the same or different and each represent a hydrogen atom, a phenyl group, an optionally substituted nitrogen-containing heterocyclic group, or a lower alkyl group which may be substituted by optionally substituted amino group(s), lower alkoxy group(s), phenyl group(s), nitrogen-containing heterocyclic group(s) or hydroxyl group(s), and R.sub.3 and R.sub.4 each represent a lower alkyl group which may be substituted by substituted amino group(s)), provided that at least one of the rings A and B is a substituted benzene ring and R is not --NHCH.sub.3, and salts thereof, and medical use of said derivative and salts.
摘要翻译： PCT No.PCT / JP96 / 02195 Sec。 371日期1997年4月3日 102（e）日期1997年4月3日PCT提交1996年8月2日PCT公布。公开号WO97 / 06145 日本公报1997年2月20日由式（1）表示的缩合茚满衍生物（1）其中环A为任选取代的苯环或具有低亚烷基二氧基的苯环，环B为任选取代的苯环或具有低级亚烷基二氧基的苯环，R为基团-NR1R2，任选取代的含氮杂环基，-OR3基或-SR4基（其中R1和R2为相同或不同，各自表示氢原子，苯基，任选取代的含氮杂环基或可被任选取代的氨基取代的低级烷基，低级烷氧基，苯基基团，含氮杂环基或羟基，R 3和R 4各自表示可以被取代的氨基取代的低级烷基），条件是至少一个环A和B是取代的苯环，R不是-NHCH 3及其盐，以及所述衍生物和盐的医疗用途。

4. 发明授权

US5710162A Condensed-indan derivatives and pharmaceutically acceptable salts thereof 失效
标题翻译：缩水甘油衍生物及其药学上可接受的盐
公开(公告)号：US5710162A
公开(公告)日：1998-01-20
申请号：US713224
申请日：1996-09-12
申请人： Shinji Okazaki , Tetsuji Asao , Motoji Wakida , Keisuke Ishida , Masato Washinosu , Teruhiro Utsugi , Yuji Yamada
发明人： Shinji Okazaki , Tetsuji Asao , Motoji Wakida , Keisuke Ishida , Masato Washinosu , Teruhiro Utsugi , Yuji Yamada
IPC分类号： A61K31/44 , A61K31/473 , A61P35/00 , C07D221/18 , C07D401/12 , C07D491/04 , C07D491/056 , C07D521/00 , C07D471/00 , A61K31/435
CPC分类号： C07D231/12 , C07D221/18 , C07D233/56 , C07D249/08 , C07D401/12 , C07D491/04
摘要： A condensed-indan derivative represented by formula (1) and a pharmaceutically acceptable salt thereof: ##STR1## wherein ring A represents an optionally substituted naphthalene ring, ring B represents an optionally substituted benzene ring or a benzene ring having a lower alkylenedioxy group. Y represents --N.dbd.CR-- or --CR.dbd.N--, R represents a --NR.sub.1 R.sub.2 group, an optionally substituted nitrogen-containing heterocyclic group or a --OR.sub.3 group, wherein R.sub.1 and R.sub.2 are the same or different and each is a hydrogen atom; a phenyl group; an optionally substituted nitrogen-containing heterocyclic group; or a lower alkyl group which may be substituted by at least one selected from the group consisting of an optionally substituted amino group, a lower alkoxy group, a phenyl group, a nitrogen-containing heterocyclic group, an amine oxide group substituted by a lower alkyl group or a hydroxyl group(s); R.sub.3 represents a lower alkyl group optionally substituted by a substituted amino group.
摘要翻译：由式（1）表示的缩合 - 茚满衍生物及其药学上可接受的盐：其中环A表示任选取代的萘环，环B表示任选取代的苯环或具有低级亚烷基二氧基的苯环组。 Y表示-N = CR-或-CR = N-，R表示-NR1R2基，任选取代的含氮杂环基或-OR 3基，其中R1和R2相同或不同，各自为氢原子 ; 苯基; 任选取代的含氮杂环基; 或可以被选自任选取代的氨基，低级烷氧基，苯基，含氮杂环基，被低级烷基取代的氧化胺基中的至少一种取代的低级烷基基团或羟基; R3表示任选被取代的氨基取代的低级烷基。

5. 发明授权

US4897503A 1,1,2-triaryl-1-alkene derivatives 失效
标题翻译： 1,1,2-三芳基-1-烯烃衍生物
公开(公告)号：US4897503A
公开(公告)日：1990-01-30
申请号：US159590
申请日：1988-01-27
申请人： Tetsuji Asao , Setsuo Takeda , Yoshikazu Sugimoto , Toshiyuki Toko , Yuji Yamada , Kazuo Ogawa , Norio Unemi
发明人： Tetsuji Asao , Setsuo Takeda , Yoshikazu Sugimoto , Toshiyuki Toko , Yuji Yamada , Kazuo Ogawa , Norio Unemi
IPC分类号： C07F9/12
CPC分类号： C07F9/12
摘要： This invention provides a 1,1,2-triaryl-1-butene derivative of the formula ##STR1## wherein R.sub.1 and R.sub.2 each represent a lower alkyl group, one of R.sub.3 and R.sub.4 is a lower alkyl group and the other is a group of the formula ##STR2## (in which R.sub.5 is a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogen atom or --OPO(OH).sub.2 group); or a pharmacologically acceptable salt thereof, its preparation and agents containing the derivative for treating mammary cancer and anovulatory infertility.

6. 发明授权

US06300331B1 Naphthalimidobenzamide derivatives 失效
标题翻译：萘酰亚胺酰胺衍生物
公开(公告)号：US06300331B1
公开(公告)日：2001-10-09
申请号：US09508044
申请日：2000-03-03
申请人： Kazuharu Noguchi , Motoji Wakida , Kenji Suzuki , Yuji Yamada , Tetsuji Asao
发明人： Kazuharu Noguchi , Motoji Wakida , Kenji Suzuki , Yuji Yamada , Tetsuji Asao
IPC分类号： A61K31473
CPC分类号： C07D221/14 , C07D401/14 , C07D471/04
摘要： The present invention relates to a naphthalimidobenzamide derivative represented by the following formula (1): (wherein, R1 represents a hydrogen atom, etc., Y represents a hydrogen atom or —CON(R4)—A2—X2, R2 and R4 are the same or different and each independently represents a hydrogen atom, etc., A1 and A2 are the same or different and each independently represents an alkylene group which may be interrupted at least once by —N(R3)— (R3 representing a hydrogen atom, etc.) and X1 and X2 are the same or different and each independently represents a (hetero)aryl group which may have a substituent, etc.) or salt thereof; and a pharmaceutical comprising it as an effective ingredient. The compound is useful as an antitumor agent and the like.
摘要翻译：本发明涉及由下式（1）表示的萘二甲酰亚胺酰胺衍生物:(其中，R1表示氢原子等，Y表示氢原子或-CON（R4）-A2-X2，R2和R4表示相同或不同，各自独立地表示氢原子等，A1和A2相同或不同，并且各自独立地表示可以被-N（R3） - （R3表示氢原子，等等），X 1和X 2相同或不同，并且各自独立地表示可以具有取代基的（杂）芳基等）或其盐; 和包含它作为有效成分的药物。该化合物可用作抗肿瘤剂等。

7. 外观设计

USD987848S1 Massage appliance 有权
公开(公告)号：USD987848S1
公开(公告)日：2023-05-30
申请号：US35513659
申请日：2021-08-13
申请人： Yuji Yamada
设计人： Yuji Yamada
摘要： The patent or application file contains at least one drawing executed in color. Copies of this patent or patent application publication with color drawing(s) will be provided by the Office upon request and payment of the necessary fee.
1. Massage Appliance
2. Massage Appliance
Fig. 1.1 is a front perspective view of the first embodiment of the massage appliance;
Fig. 1.2 is a front view thereof;
Fig. 1.3 is a back view thereof;
Fig. 1.4 is a top view thereof;
Fig. 1.5 is a bottom view thereof;
Fig. 1.6 is a left view thereof;
Fig. 1.7 is a right view thereof;
Fig. 2.1 is a front perspective view of the second embodiment of the massage appliance;
Fig. 2.2 is a front view thereof;
Fig. 2.3 is a back view thereof;
Fig. 2.4 is a top view thereof;
Fig. 2.5 is a bottom view thereof;
Fig. 2.6 is a left view thereof; and
Fig. 2.7 is a right view thereof.

8. 发明授权

US08644531B2 Information processing system and information processing method 有权
标题翻译：信息处理系统和信息处理方法
公开(公告)号：US08644531B2
公开(公告)日：2014-02-04
申请号：US12634999
申请日：2009-12-10
申请人： Homare Kon , Yuji Yamada
发明人： Homare Kon , Yuji Yamada
IPC分类号： H04R5/02
CPC分类号： H04S7/304 , H04S2400/01
摘要： An information processing system includes a display, a display sensor that detects a movement or a rotation of the display, a transducer unit as an earphone unit or a headphone unit, a sound processing part that processes an audio signal so as to localize a sound image in a position outside a head of a listener wearing the transducer unit and listening to sound, and an operation controller that computes an output from the display sensor to obtain a moving direction and a moving distance, or a rotation direction and a rotation angle of the display, and controls sound processing performed by the sound processing part in accordance with a result of the computation so that a positional relation between the display and the head of the listener is mapped as a positional relation between an image display surface and the head of the listener in a virtual viewing space.
摘要翻译：信息处理系统包括显示器，检测显示器的移动或旋转的显示传感器，作为耳机单元或耳机单元的换能器单元，处理音频信号以便将声音图像定位的声音处理部件在佩戴换能器单元并收听声音的听众的头部外的位置，以及操作控制器，其计算来自显示传感器的输出以获得移动方向和移动距离，或者旋转方向和旋转角度根据计算结果显示和控制由声音处理部分执行的声音处理，使得显示器和听众的头部之间的位置关系被映射为图像显示表面和图像显示面的头部之间的位置关系监听器在虚拟观看空间中。

9. 发明申请

US20120106763A1 AUDIO SIGNAL PROCESSING DEVICE, AUDIO SIGNAL PROCESSING METHOD, AND PROGRAM 有权
标题翻译：音频信号处理设备，音频信号处理方法和程序
公开(公告)号：US20120106763A1
公开(公告)日：2012-05-03
申请号：US13278644
申请日：2011-10-21
申请人： Koyuru OKIMOTO , Yuji Yamada
发明人： Koyuru OKIMOTO , Yuji Yamada
IPC分类号： H04R1/02
CPC分类号： H04S7/301 , H04R2499/13 , H04R2499/15 , H04S7/302 , H04S7/305
摘要： An audio signal processing device includes two audio signal processing units that serially perform a processing with respect to an input audio signal, and obtain an output audio signal for driving a speaker. One audio signal processing unit of the two audio signal processing units performs, with respect to the input audio signal, a correction process through a filter that realizes a reverse characteristic of an impulse response measured at a first measurement position that is a front position of the speaker. The other audio signal processing unit performs, with respect to the input audio signal, a correction process through a filter that realizes a reverse characteristic of an impulse response measured at a second measurement position different from the first measurement position that is a front position of the speaker.
摘要翻译：音频信号处理装置包括对输入音频信号进行串行处理的两个音频信号处理单元，并获得用于驱动扬声器的输出音频信号。两个音频信号处理单元的一个音频信号处理单元相对于输入音频信号执行通过滤波器的校正处理，该滤波器实现在作为第一测量位置的第一测量位置处测量的脉冲响应的反向特性扬声器。另一个音频信号处理单元相对于输入音频信号执行通过滤波器的校正处理，该滤波器实现在与作为第一测量位置的第一测量位置不同的第二测量位置处测量的脉冲响应的反向特性扬声器。

10. 发明授权

US08122584B2 Method of producing honeycomb structure molding die 有权
标题翻译：生产蜂窝结构成型模具的方法
公开(公告)号：US08122584B2
公开(公告)日：2012-02-28
申请号：US12003417
申请日：2007-12-26
申请人： Toshiji Kondou , Yuji Yamada , Kunitsugu Mototani
发明人： Toshiji Kondou , Yuji Yamada , Kunitsugu Mototani
IPC分类号： B23P13/04
CPC分类号： B23P15/243 , B28B2003/203 , B29C47/0028 , B29C47/12 , B29L2031/60 , Y10T29/49002 , Y10T29/49169 , Y10T29/49172 , Y10T29/49995 , Y10T29/49996
摘要： In a method of producing a honeycomb structure molding die composed of feed holes through which molding material is fed and slit grooves communicated with the feed holes for the use of molding a honeycomb structure body, the slit grooves are formed on one surface of a metal material in a lattice arrangement by repeatedly moving a thin circular grindstone blade which is rotating in a straight-line direction or a line direction approximating a straight line in order to cut the surface of the metal material. In particular, the method removes fine metal powder, generated by cutting the surface of the metal material, using polishing grooves formed in a dressing grindstone disposed in front of the metal material every cutting of the metal material during the slit groove formation.
摘要翻译：在制造蜂窝结构体成型模具的方法中，所述蜂窝结构体成形模具由供给成形材料的供给孔和与用于成形蜂窝结构体的进给孔连通的狭缝槽构成，所述狭缝槽形成在金属材料的一个面上通过重复移动沿着直线方向或近似直线的线方向旋转的细圆形磨石刀片以切割金属材料的表面，以格子布置。特别地，该方法通过在切槽形成期间每次切割金属材料时，使用在金属材料前方设置的修整磨石中形成的抛光槽来除去金属材料的表面产生的细金属粉末。

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