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1. 发明授权

US5481393A Pupil modulation optical system 失效
标题翻译：瞳孔调制光学系统
公开(公告)号：US5481393A
公开(公告)日：1996-01-02
申请号：US149335
申请日：1993-11-09
申请人： Shingo Kashima , Shinichi Hayashi
发明人： Shingo Kashima , Shinichi Hayashi
IPC分类号： G02B27/58 , G02B26/02 , G02B5/22
CPC分类号： G02B27/58
摘要： A pupil modulation optical system which enables pupil modulation modes to be readily changed over from one to another and makes it possible to readily form an image of high resolution and high contrast. The optical system has a condenser lens (1) and an objective lens (2). Intensity modulation filters (3) and (4) for pupil modulation are disposed at at least two different pupil positions or positions equivalent to pupils of the optical system. By controlling the intensity distributions of the filters (3) and (4), various pupil modulation effects, e.g., contrast increasing effect, resolution improving effect, are obtained.
摘要翻译：瞳孔调制光学系统使得光瞳调制模式能够容易地从一个转换到另一个，并且使得可以容易地形成高分辨率和高对比度的图像。光学系统具有聚光透镜（1）和物镜（2）。用于光瞳调制的强度调制滤波器（3）和（4）被设置在与光学系统的光瞳相当的至少两个不同的光瞳位置或位置上。通过控制滤光器（3）和（4）的强度分布，可以获得各种光瞳调制效果，例如对比度增加效果，分辨率改善效果。

2. 发明授权

US5334830A Scanning optical microscope having a compact confocal optical system for adjusting position of aperture 失效
标题翻译：扫描光学显微镜具有用于调节孔径位置的紧凑型共焦光学系统
公开(公告)号：US5334830A
公开(公告)日：1994-08-02
申请号：US004458
申请日：1993-01-14
申请人： Hiroya Fukuyama , Hisao Kitagawa , Mitsunori Yamamoto , Shingo Kashima
发明人： Hiroya Fukuyama , Hisao Kitagawa , Mitsunori Yamamoto , Shingo Kashima
IPC分类号： G02B21/00 , H01J3/14
CPC分类号： G02B21/0032 , G02B21/0048 , G02B21/0076
摘要： A laser beam from a light source is reflected by a beam splitter and two galvanomirrors, and enters a pupil projection lens. The beam passing through the lens forms a spot on an image plane of an objective. This spot is two-dimensionally scanned by shaking the galvanomirrors with respect to their axes perpendicular to each other. Reflected light or fluorescence from a sample is returned to the beam splitter through the same path, passes through it, and is then reflected by a mirror. This optical system includes an optical unit which can be inserted/removed therein/therefrom. When the optical unit is removed, the optical system serves as a confocal optical system. When the optical unit is inserted, the optical system serves as a nonconfocal optical system. In the confocal optical system, the beam from the mirror enters a condenser, converges, passes through an iris and enters a photomultiplier tuber. The condenser includes a convex lens and a concave lens. In the nonconfocal optical system, the beam from the mirror enters a condenser, converges and is focused on the iris to a spot. The beam passing through the iris enters the photomultiplier tube.
摘要翻译：来自光源的激光束被分束器和两个电流镜反射，并且进入瞳孔投影透镜。穿过透镜的光束在物镜的图像平面上形成一个点。通过相对于它们彼此垂直的轴线摇动电镜镜来对该点进行二维扫描。来自样品的反射光或荧光通过相同的路径返回到分束器，通过它，然后被反射镜反射。该光学系统包括可以在其中插入/移除的光学单元。当光学单元被去除时，光学系统用作共焦光学系统。当插入光学单元时，光学系统用作非共焦光学系统。在共焦光学系统中，来自镜子的光束进入冷凝器，会聚，通过虹膜并进入光电倍增块。冷凝器包括凸透镜和凹透镜。在非共焦光学系统中，来自反射镜的光束进入聚光器，会聚并聚焦在虹膜上。通过虹膜的光束进入光电倍增管。

3. 发明授权

US5144496A Reflecting objective system including a negative optical power second mirror with increasing negative optical power off-axis 失效
标题翻译：反射目标系统，包括增加负偏光功率的轴负反射光功率第二镜
公开(公告)号：US5144496A
公开(公告)日：1992-09-01
申请号：US553639
申请日：1990-07-18
申请人： Shingo Kashima
发明人： Shingo Kashima
IPC分类号： G02B17/06 , G02B21/04
CPC分类号： G02B21/04 , G02B17/061 , G02B17/0631 , G02B17/0652
摘要： A reflecting objective system comprising three or more spherical reflecting mirrors arranged symmetrically with regard to an optical axis common thereto and has spherical aberration corrected very favorably. By using a single or plural aspherical surfaces, this reflecting objective system can be modified so as to comprise two or more reflecting mirrors and correct not only the spherical aberration but also the offaxial aberrations.
摘要翻译：一种反射物镜系统，包括三个或更多个相对于其共同的光轴对称布置的球面反射镜，并且非常有利地校正了球面像差。通过使用单个或多个非球面，该反射物镜系统可以被修改为包括两个或更多个反射镜，并且不仅校正球面像差而且校正离轴像差。

4. 发明授权

US06671089B2 Optical filter and illumination optical system provided with same 有权
标题翻译：光滤波器和照明光学系统同样提供
公开(公告)号：US06671089B2
公开(公告)日：2003-12-30
申请号：US10024709
申请日：2001-12-21
申请人： Hiroyuki Nishida , Shingo Kashima
发明人： Hiroyuki Nishida , Shingo Kashima
IPC分类号： G02B2106
CPC分类号： G02B21/16
摘要： An optical filter has a spectral transmittance characteristic plotted as a curve that is not mirror-symmetric with respect to any vertical axis upon wavelength being taken along the axis of abscissa and transmittance being taken along the axis of ordinate. The optical filter can be designed and fabricated easily and efficiently. The optical filter is used with a light source that causes self-absorption, to constitute an illumination optical system. In the illumination optical system, an image of the arc lamp is projected with a sufficiently high magnification in good aberration condition on the pupil of the objective lens, light in a wavelength region that was conventionally unused is efficiently used, and, in addition, the heat problem is solved.
摘要翻译：光学滤波器具有作为曲线绘制的光谱透射率特性，其作为沿着横坐标轴取波长而相对于任何垂直轴不是镜像对称的曲线，并且透射率沿纵轴取。滤光片可以容易且高效地设计和制造。光滤波器与引起自吸收的光源一起使用，构成照明光学系统。在照明光学系统中，在物镜的光瞳上以良好的像差状态以足够高的倍率投影弧光灯的图像，有效地使用以往未使用的波长区域的光，另外，热问题解决了。

5. 发明授权

US06507442B2 Objective lens 有权
标题翻译：物镜
公开(公告)号：US06507442B2
公开(公告)日：2003-01-14
申请号：US09793566
申请日：2001-02-27
申请人： Shingo Kashima , Takehiro Yoshida
发明人： Shingo Kashima , Takehiro Yoshida
IPC分类号： G02B2102
CPC分类号： G02B21/02
摘要： An objective lens includes a first lens unit constructed with a plurality of single lenses, having a negative power as a whole, and a second lens unit constructed with a plurality of single lenses, arranged on the object side of the first lens unit. Each of the first and second lens units is provided with air spaces between positive and negative lenses of different media and has at least one pair of lenses designed to satisfy all the following conditions when the parfocal distance of the objective lens is denoted by L (mm), an air apace by d (mm), the radius of curvature of a lens surface with a positive power opposite to the air space by Rp, and the radius of curvature of a lens surface with a negative power opposite to the air space by Rn, and in addition to the pair of lenses, the second lens unit has at least one single positive biconvex lens and at least one single positive meniscus lens, and thereby it becomes possible to correct chromatic aberration and to favorably obtain resolution corresponding to a high numerical aperture and a wavelength used: 0.01
摘要翻译：物镜包括由多个单一透镜构成的第一透镜单元，整个具有负光焦度，以及第二透镜单元，该第一透镜单元设置在第一透镜单元的物体侧上，具有多个单透镜。第一和第二透镜单元中的每一个在不同介质的正透镜和负透镜之间设置有空气空间，并且具有至少一对透镜，其被设计成当物镜的对焦距离由L（mm）表示时满足以下所有条件），通过d（mm）的空气宽度，具有与空气空间相反的正功率的透镜表面的曲率半径Rp，以及具有与空气空间相反的负功率的透镜表面的曲率半径由 Rn，并且除了一对透镜之外，第二透镜单元具有至少一个单个正双凸透镜和至少一个单个正弯月形透镜，从而可以校正色差并有利地获得对应于高的透镜数值孔径和使用的波长：0.01

6. 发明授权

US5202795A Eyepieces 失效
标题翻译：目镜
公开(公告)号：US5202795A
公开(公告)日：1993-04-13
申请号：US781993
申请日：1991-10-22
申请人： Shingo Kashima
发明人： Shingo Kashima
IPC分类号： G02B13/18 , G02B25/00
CPC分类号： G02B13/18 , G02B25/001
摘要： The invention relates to an eyepiece that has an improved image surface flatness even at a wider field angle, is well corrected for various aberrations inclusive chromatic aberration of pupil and is usable with inexpensive microscopes (esp., stereoscopic ones). The eyepiece of the invention is an eyepiece including at least three lens components comprising a cemented lens component consisting positive and negative lens elements and a lens component having a negative refractive power in its entirety, characterized in that the lens component other than the lens components proximate to the object and eye sides is provided with a plastic lens element or elements having at least one aspherical surface.
摘要翻译：本发明涉及即使在更宽的视场角下也具有改善的图像表面平坦度的目镜，对于包括瞳孔的色差的各种像差而被良好地校正，并且可用于廉价的显微镜（特别是立体显微镜）。本发明的目镜是包括至少三个透镜部件的目镜，该透镜部件包括由透镜组件构成的正透镜元件和负透镜元件以及整体具有负屈光力的透镜元件，其特征在于，透镜元件除了透镜元件之外物体和眼睛侧设置有具有至少一个非球面的塑料透镜元件或元件。

7. 发明授权

US6094300A Laser scanning microscope 失效
标题翻译：激光扫描显微镜
公开(公告)号：US6094300A
公开(公告)日：2000-07-25
申请号：US972591
申请日：1997-11-18
申请人： Shingo Kashima , Yosuke Kishi
发明人： Shingo Kashima , Yosuke Kishi
IPC分类号： G01N21/64 , G02B21/00 , G02B21/16 , G02B21/18 , G02B21/06 , G01J3/30 , G02B26/08
CPC分类号： G02B21/002 , G02B21/16
摘要： A laser scanning microscope having a first scanning optical system that causes coherent light projected from a first laser light source to scan a specimen, and a second scanning optical system that projects coherent light output from a second laser light source at a given position on the specimen. Fluorescence from the specimen is measured by a photoelectric conversion element.
摘要翻译：一种具有第一扫描光学系统的激光扫描显微镜，其使得从第一激光光源投射的相干光扫描样本;以及第二扫描光学系统，其将来自第二激光光源的相干光输出到所述样本上的给定位置。通过光电转换元件测量样品的荧光。

8. 发明授权

US5406421A Cover slip for use in microscope 失效
标题翻译：覆盖滑块用于显微镜
公开(公告)号：US5406421A
公开(公告)日：1995-04-11
申请号：US185759
申请日：1994-01-24
申请人： Shingo Kashima , Asako Kashima
发明人： Shingo Kashima , Asako Kashima
IPC分类号： G02B21/33 , G02B21/34 , G02B5/00
CPC分类号： G02B21/34 , G02B21/33
摘要： A cover slip for use in a microscope, which is employed for a water-immersed objective lens, is made of a transparent material with a refractive index, the difference between the refractive index of the transparent material and that of water being 0.02 or less.
摘要翻译：在用于浸水式物镜的显微镜中使用的覆盖片由具有折射率的透明材料制成，透明材料的折射率与水的折射率之差为0.02以下。

9. 发明授权

US5191473A Objectives 失效
标题翻译：目标
公开(公告)号：US5191473A
公开(公告)日：1993-03-02
申请号：US781846
申请日：1991-10-24
申请人： Shingo Kashima , Chikara Nagano
发明人： Shingo Kashima , Chikara Nagano
IPC分类号： G02B21/02
CPC分类号： G02B21/02
摘要： An objective of some 10 magnifications usable with microscopes, etc. which has an increased numerical aperture and working distance, including a first lens component that is a cemented lens consisting of negative and positive lens elements, a second lens component a third lens component, a fourth lens component consisting of a cemented lens and a fifth lens component having a positive refractive power, characterized by satisfying the following conditions:.nu..sub.I2 -.nu..sub.I1 >20 (1)n.sub.I1 -n.sub.I2 >0.2 (2)wherein:n.sub.I1 is the refractive index of d-line of the negative lens element of the first component,.nu..sub.I1 is the Abbe's number of said negative lens element of the first lens component,n.sub.I2 is the refractive index for d-line of the positive lens element of the first lens component, and.nu..sub.I2 is the Abbe's number of said positive lens element of the first lens component.
摘要翻译：具有可用于具有增加的数值孔径和工作距离的显微镜等的大约10倍的目标，包括由负和正透镜元件组成的胶合透镜的第一透镜部件，第二透镜部件，第三透镜部件，第四透镜部件由胶合透镜和具有正折光力的第五透镜部件组成，其特征在于满足以下条件：nu I2-nu I1> 20（1）nI1-nI2> 0.2（2）其中：nI1是折射率第一分量的负透镜元件的d线的折射率，nu I1是第一透镜部件的所述负透镜元件的阿贝数，nI2是第一透镜的正透镜元件的d线的折射率分量，nu I2是第一透镜组件的所述正透镜元件的阿贝数。

10. 发明授权

US06184535B2 Method of microscopic observation 有权
标题翻译：显微镜观察方法
公开(公告)号：US06184535B2
公开(公告)日：2001-02-06
申请号：US09156775
申请日：1998-09-18
申请人： Shingo Kashima , Yoshinori Iketaki
发明人： Shingo Kashima , Yoshinori Iketaki
IPC分类号： G01N2164
CPC分类号： G01N21/6458 , G01N21/6428 , G01N2021/6419 , G02B21/002 , G02B21/16
摘要： In a method of observing a specimen through a fluorescence microscope, molecules that could cause double-resonance absorption process in an appropriate manner are used to dye the specimen, and the specimen is irradiated with a plurality of light beams of different wavelengths in a good timing, so that a microscopic image with high spatial resolution is obtained. In the microscope to be used in the method of observation, the specimen is irradiated with two light beams of different wavelength bands via an aperture with an annular-zonal structure and an optical system that has different in-focus positions for these two wavelength bands, so that one of the two light beam is focused on a surface of the specimen and the other light beam is defocused thereon. Consequently, the microscope achieves improvement of the spatial resolution as to overcome the diffraction limit determined by the wavelengths in use.
摘要翻译：在通过荧光显微镜观察样品的方法中，使用可以以适当的方式引起双共振吸收过程的分子染色样品，并且以良好的时间用多个不同波长的光束照射样品，从而获得具有高空间分辨率的显微图像。在用于观察方法的显微镜中，通过具有环形区域结构和光学系统的孔径，用两个不同波长带的光束照射样品对于这两个波长带具有不同的对焦位置，使得两个光束中的一个被聚焦在样本的表面上，并且另一个光束在其上散焦。因此，显微镜实现空间分辨率的提高，以克服由使用的波长确定的衍射极限。

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