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1. 发明授权

US4796036A Capsule rupture printing system 失效
标题翻译：胶囊破裂打印系统
公开(公告)号：US4796036A
公开(公告)日：1989-01-03
申请号：US59732
申请日：1987-06-08
申请人： Shigemi Misono , Makoto Ueda , Kazuto Shikino , Tomoyuki Torii , Keiichi Ishiyama , Toshiharu Aoyagi
发明人： Shigemi Misono , Makoto Ueda , Kazuto Shikino , Tomoyuki Torii , Keiichi Ishiyama , Toshiharu Aoyagi
IPC分类号： B41J2/525 , B41J2/445 , B41J2/48 , G03B27/32 , G03D13/00 , G03F7/00 , H04N1/50 , G01D9/42 , H04N1/46
CPC分类号： H04N1/506 , B41J2/48 , G03F7/0022 , G03B2227/325
摘要： Apparatus is provided for use in printing systems wherein regions of rupturable capsule layer are ruptured to release dye that prints an image on an image-receiving sheet. An optical valve member is positioned between a light source and an imaging sheet which has the layer of capsules on its surface. An image pattern formed on a ferroelectric ceramic plate of the optical valve member by the irradiation of an electron beam together with an ultraviolet light in accordance with each color separation signal is projected onto the imaging sheet. The imaging sheet projected with the image is positioned so that the layer of capsules lies between the imaging sheet and the image-receiving sheet. A pressure roller applies pressure against the imaging sheet and the image-receiving sheet to rupture the capsules between them to thereby transfer the dye to the image-receiving sheet.
摘要翻译：提供了用于打印系统的设备，其中可破裂胶囊层的区域被破裂以释放在图像接收片材上打印图像的染料。光学阀构件位于光源和其表面上具有胶囊层的成像片之间。通过根据每个颜色分离信号的电子束与紫外光的照射形成在光阀构件的铁电陶瓷板上的图像图案被投影到成像片上。放映图像的成像片被定位成使得胶囊层位于成像片和图像接收片之间。压力辊对成像片和图像接收片施加压力以破坏它们之间的胶囊，从而将染料转移到图像接收片材。

2. 发明授权

US4748475A Color printing system 失效
标题翻译：彩色打印系统
公开(公告)号：US4748475A
公开(公告)日：1988-05-31
申请号：US59733
申请日：1987-06-08
申请人： Keiichi Ishiyama , Makoto Ueda , Shigemi Misono , Tomoyuki Torii , Kazuto Shikino , Toshiharu Aoyagi
发明人： Keiichi Ishiyama , Makoto Ueda , Shigemi Misono , Tomoyuki Torii , Kazuto Shikino , Toshiharu Aoyagi
IPC分类号： B41J2/52 , G03C1/00 , G03C7/46 , H04N1/23 , G03B27/32 , G03B27/52
CPC分类号： G03C1/002 , G03C7/46 , G03B2227/325
摘要： Apparatus is provided for use in color printing systems wherein an image is projected by a plural monochrome pictures corresponding to the pictures separated into three primary colors onto an imaging sheet which contains a dye and a photosensitive composition encapsulated in a layer of pressure rupturable capsules. The imaging sheet projected the image is positioned so the layer of capsules lies between the imaging sheet and an image-receiving sheet. A pressure roller applies pressure against the imaging sheet and the image-receiving sheet to rupture the capsules between them and thereby transfer the dye to the image-receiving sheet.
摘要翻译：提供了用于彩色打印系统的设备，其中通过与分离成三原色的图像相对应的多个单色图像将图像投影到包含染料的胶片和包含在压力可破裂胶囊层中的感光组合物的成像片上。投影图像的成像片定位成使得胶囊层位于成像片和图像接收片之间。压力辊对成像片和图像接收片施加压力以破坏它们之间的胶囊，从而将染料转印到图像接收片材上。

3. 发明授权

US09273332B2 Method for production of L-amino acid 有权
标题翻译： L-氨基酸生产方法
公开(公告)号：US09273332B2
公开(公告)日：2016-03-01
申请号：US12445233
申请日：2007-10-11
申请人： Hiroyuki Kanamaru , Makoto Ueda , Hirokazu Nanba
发明人： Hiroyuki Kanamaru , Makoto Ueda , Hirokazu Nanba
IPC分类号： C12P13/06 , C12P13/08 , C12P13/22 , C12P13/04 , C12N9/02
CPC分类号： C12P13/06 , C12N9/0008 , C12N9/0073 , C12P13/04 , C12P13/08 , C12P13/222
摘要： The present invention has its object to provide a method for producing an L-amino acid comprising reacting a keto acid with an amino acid dehydrogenase and an enzyme having coenzyme regenerating ability to convert to a L-amino acid, wherein a coenzyme is added in two or more portions in the reaction. The method of the present invention enables efficient production of an L-amino acid useful as a synthetic intermediate such as a pharmaceutical intermediate with high optical purity by an enzymatic reductive amination independent of the purity of the keto acid used as a substrate.
摘要翻译：本发明的目的是提供一种生产L-氨基酸的方法，其包括使酮酸与氨基酸脱氢酶和具有辅酶再生能力的酶反应以转化为L-氨基酸，其中将辅酶加入二或更多的部分。本发明的方法可以独立于用作底物的酮酸的纯度，有效地生产可用作合成中间体的L-氨基酸，例如具有高光学纯度的药物中间体，通过酶还原胺化。

4. 发明授权

US08008461B2 Carbonyl reductase, gene therefor and use thereof 失效
标题翻译：羰基还原酶，其基因及其用途
公开(公告)号：US08008461B2
公开(公告)日：2011-08-30
申请号：US11665065
申请日：2005-10-20
申请人： Noriyuki Kizaki , Makoto Ueda , Daisuke Moriyama , Naoaki Taoka , Yoshihiko Yasohara
发明人： Noriyuki Kizaki , Makoto Ueda , Daisuke Moriyama , Naoaki Taoka , Yoshihiko Yasohara
IPC分类号： C07H21/04 , C12N9/02 , C12P21/02 , C12P13/00 , C07C255/01
CPC分类号： C12N9/0006 , C12P7/04 , C12P7/62 , C12P13/002 , C12P41/002
摘要： The present invention is to provide a process for efficiently producing an optically active alcohol including (R)-3-hydroxy-3-phenylpropanenitrile. One of the features of the present invention is a polypeptide having an activity of asymmetrically reducing 3-oxo-3-phenylpropanenitrile isolated from a microorganism belonging to the genus Candida to produce (R)-3-hydroxy-3-phenylpropanenitrile, DNA encoding the polypeptide and a transformant of producing the polypeptide. Another feature of the present invention is a process for producing an optically active alcohol such as (R)-3-hydroxy-3-phenylpropanenitrile by reducing a carbonyl compound such as 3-oxo-3-phenylpropanenitrile by use of the polypeptide or the transformant.
摘要翻译：本发明提供一种有效制备包含（R）-3-羟基-3-苯基丙腈的光学活性醇的方法。本发明的特征之一是具有不对称还原从属于念珠菌属的微生物分离的3-氧代-3-苯基丙腈的活性的多肽，以产生（R）-3-羟基-3-苯基丙腈，编码多肽和产生多肽的转化体。本发明的另一个特征是通过使用多肽或转化体还原羰基化合物如3-氧代-3-苯基丙腈来制备光学活性醇如（R）-3-羟基-3-苯基丙腈的方法。

5. 发明申请

US20100065750A1 BURN-UP PROFILE MEASURING METHOD, BURN-UP PROFILE MEASURING APPARATUS, RADIATION SIGNAL DISTRIBUTION MEASURING APPARATUS, AND BURN-UP PROFILE MEASURING PROGRAM 有权
标题翻译：燃烧轮廓测量方法，燃烧轮廓测量装置，辐射信号分布测量装置和燃烧轮廓测量程序
公开(公告)号：US20100065750A1
公开(公告)日：2010-03-18
申请号：US12595546
申请日：2008-04-11
申请人： Hironori Kumanomido , Naotaka Oda , Yutaka Tokiwa , Makoto Ueda
发明人： Hironori Kumanomido , Naotaka Oda , Yutaka Tokiwa , Makoto Ueda
IPC分类号： G01T3/00 , G01T1/185
CPC分类号： G21C17/063 , G21Y2002/201 , G21Y2002/204 , G21Y2004/30 , G21Y2004/40
摘要： An upper detector and a lower detector that face at least one side of a fuel assembly, on which neutrons are irradiated in a nuclear reactor, and detect radiation are set at a predetermined interval in an axial direction of the fuel assembly. Distributions of radiation signals are measured by the upper detector and the lower detector while the fuel assembly and the upper detector and the lower detectors are relatively moved along the axial direction of the fuel assembly. Soundness of radiation signals measured by the upper detector and the lower detector is determined in every measurement by comparing radiation signal distributions obtained by measuring the same portion in the axial direction of the fuel assembly in a multiplexed manner with the upper detector and the lower detector. Thereafter, relative burn-up is calculated by utilizing the measured radiation signals to measure a burn-up profile. According to the present invention, it is possible to measure a burn-up profile of the fuel assembly while securing reliability of a measurement result.
摘要翻译：面向燃料组件的至少一侧的上检测器和下检测器，其中在核反应堆中辐射中子并检测辐射，沿燃料组件的轴向方向被设定为预定的间隔。辐射信号的分布由上检测器和下检测器测量，而燃料组件和上检测器和下检测器沿着燃料组件的轴向方向相对移动。通过比较通过以多路复用方式与上部检测器和下部检测器测量燃料组件的轴向方向上的相同部分而获得的辐射信号分布，在每次测量中确定由上部检测器和下部检测器测量的辐射信号的良好性。此后，通过利用测量的辐射信号来计算相对燃耗以测量燃尽曲线。根据本发明，可以在确保测量结果的可靠性的同时测量燃料组件的燃尽曲线。

6. 发明授权

US07659409B2 3-Hydroxy-3-(2-thienyl) propionamides and production method thereof, and production method of 3-amino-1-(2-thienyl)-1-propanols using the same 失效
标题翻译： 3-羟基-3-（2-噻吩基）丙酰胺及其制备方法和使用其的3-氨基-1-（2-噻吩基）-1-丙醇的制备方法
公开(公告)号：US07659409B2
公开(公告)日：2010-02-09
申请号：US10944055
申请日：2004-09-20
申请人： Jun Takehara , Jingping Qu , Kazuaki Kanno , Hiroshi Kawabata , Yasumasa Dekishima , Makoto Ueda , Kyoko Endo , Takeshi Murakami , Tomoko Sasaki , Hisatoshi Uehara , Youichi Matsumoto , Shihomi Suzuki
发明人： Jun Takehara , Jingping Qu , Kazuaki Kanno , Hiroshi Kawabata , Yasumasa Dekishima , Makoto Ueda , Kyoko Endo , Takeshi Murakami , Tomoko Sasaki , Hisatoshi Uehara , Youichi Matsumoto , Shihomi Suzuki
IPC分类号： C07D333/22
CPC分类号： C07D333/16 , B01J31/1805 , B01J31/2295 , B01J2231/643 , B01J2531/80 , B01J2531/821
摘要： The object of the present invention is to provide 3-hydroxy-3-(2-thienyl)propionamides useful as synthesis intermediates of pharmaceutical preparations and the like and a method for obtaining optically active 3-amino-1-(2-thienyl)-1-propanols using the same with high reaction yield, high optical yield and industrially low cost.According to the present invention, 3-amino-1-(2-thienyl)-1-propanols are obtained by carrying out asymmetric reduction of a β-ketocarbonyl compound having thiophene ring in the presence of a catalyst constituted from a compound of a group VIII or IX metal in the periodic table (e.g., a ruthenium compound) and an asymmetric ligand represented by a specified optically active diamine derivative (e.g., a diphenylethylenediamine derivative), or using a cell, a treated product of said cell or the like of a microorganism, and as occasion demands, carrying out amidation of the ester group and then carrying out reduction of the amido group. (each of the substituents is as described in claim 1).
摘要翻译：本发明的目的是提供可用作药物制剂等的合成中间体的3-羟基-3-（2-噻吩基）丙酰胺和获得光学活性3-氨基-1-（2-噻吩基）使用相同的1-丙醇，反应产率高，光学收率高，工业成本低。根据本发明，3-氨基-1-（2-噻吩基）-1-丙醇通过在由组合的化合物构成的催化剂存在下进行具有噻吩环的β-酮羰基化合物的不对称还原而得到 VIII或IX族金属（例如钌化合物）和由特定光学活性二胺衍生物（例如二苯基乙二胺衍生物）表示的不对称配体，或使用电池，所述电池等的处理产物微生物，根据需要，进行酯基的酰胺化，然后进行酰胺基的还原。（每个取代基如权利要求1所述）。

7. 发明申请

US20100028959A1 METHOD FOR PRODUCTION OF L-AMINO ACID 有权
标题翻译： L-氨基酸生产方法
公开(公告)号：US20100028959A1
公开(公告)日：2010-02-04
申请号：US12445233
申请日：2007-10-11
申请人： Hiroyuki Kanamaru , Makoto Ueda , Hirokazu Nanba
发明人： Hiroyuki Kanamaru , Makoto Ueda , Hirokazu Nanba
IPC分类号： C12P13/06 , C12P13/04
CPC分类号： C12P13/06 , C12N9/0008 , C12N9/0073 , C12P13/04 , C12P13/08 , C12P13/222
摘要： The present invention has its object to provide a method for producing an L-amino acid comprising reacting a keto acid with an amino acid dehydrogenase and an enzyme having coenzyme regenerating ability to convert to a L-amino acid, wherein a coenzyme is added in two or more portions in the reaction. The method of the present invention enables efficient production of an L-amino acid useful as a synthetic intermediate such as a pharmaceutical intermediate with high optical purity by an enzymatic reductive amination independent of the purity of the keto acid used as a substrate.
摘要翻译：本发明的目的是提供一种生产L-氨基酸的方法，其包括使酮酸与氨基酸脱氢酶和具有辅酶再生能力的酶反应以转化为L-氨基酸，其中将辅酶加入二或更多的部分。本发明的方法可以独立于用作底物的酮酸的纯度，有效地生产可用作合成中间体的L-氨基酸，例如具有高光学纯度的药物中间体，通过酶还原胺化。

8. 发明申请

US20080233621A1 Method For Producing Alcohol and Carboxylic Acid Having Optical Activity 审中-公开
标题翻译：生产具有光学活性的醇和羧酸的方法
公开(公告)号：US20080233621A1
公开(公告)日：2008-09-25
申请号：US10588286
申请日：2005-02-04
申请人： Yasumasa Dekishima , Hiroshi Kawabata , Hirotoshi Hiraoka , Makoto Ueda , Hisatoshi Uehara
发明人： Yasumasa Dekishima , Hiroshi Kawabata , Hirotoshi Hiraoka , Makoto Ueda , Hisatoshi Uehara
IPC分类号： C12P7/44 , C12P7/04 , C12P7/40
CPC分类号： C12P7/04 , C07B2200/07 , C07C51/00 , C07C51/08 , C07C51/09 , C07C67/343 , C07C303/28 , C12P7/40 , C12P7/44 , C07C53/126 , C07C55/02 , C07C69/34 , C07C309/66
摘要： It is an object of the present invention to provide an inexpensive and efficient industrial method for obtaining (S)-2-pentanol, (S)-2-hexanol, 1-methylalkyl malonic acid and 3-methyl carboxylic acid at a high optical purity. The present invention provides a method of producing (S)-2-pentanol or (S)-2-hexanol which comprises allowing certain types of microorganisms or transformed cells, a product obtained by treating said microorganisms or cells, a culture solution of said microorganisms or cells, and/or a crude purified product or purified product of a carbonyl reductase fraction obtained from said microorganisms or cells, to act on 2-pentanone or 2-hexanone.
摘要翻译：本发明的目的是提供一种廉价且高效的工业方法，以高光学纯度获得（S）-2-戊醇，（S）-2-己醇，1-甲基烷基丙二酸和3-甲基羧酸。本发明提供一种生产（S）-2-戊醇或（S）-2-己醇的方法，其包括将某些类型的微生物或转化细胞，即通过处理所述微生物或细胞获得的产物，所述微生物或转化细胞的培养液或细胞，和/或粗制纯化产物或由所述微生物或细胞获得的羰基还原酶级分的纯化产物作用于2-戊酮或2-己酮。

9. 发明申请

US20070076839A1 Axial void fraction distribution measurement method and neutron multiplication factor evaluating method 审中-公开
$Axial void fraction distribution measurement method and neutron multiplication factor evaluating method$
标题翻译：轴向空隙率分布测量方法和中子倍增因子评估方法
公开(公告)号：US20070076839A1
公开(公告)日：2007-04-05
申请号：US11434195
申请日：2006-05-16
申请人： Makoto Ueda , Hironori Kumanomido , Ishi Mitsuhashi , Tsukasa Kikuchi , Kenichi Yoshioka , Tomoharu Sasaki , Kouji Hiraiwa
发明人： Makoto Ueda , Hironori Kumanomido , Ishi Mitsuhashi , Tsukasa Kikuchi , Kenichi Yoshioka , Tomoharu Sasaki , Kouji Hiraiwa
IPC分类号： G21C3/32
CPC分类号： G21C1/084 , G21C17/10 , Y02E30/31
摘要： A first intensity Az expressed as Az=az×Eα, a first reference intensity Ao expressed as Ao=ao×Eα, a second intensity Bz expressed as Bz=bz×E, and a second reference intensity Bo=bo×E, are evaluated. The first intensity and the first reference intensity are of radioactive nuclides generated by a neutron capture reaction of a heavy nuclide or a fission product nuclide. The second intensity and the second reference intensity are of radioactive fission product nuclides except nuclides generated by a neutron capture reaction. The reference intensities are measured where the void fraction is known. Also a correlation curve of (az/ao) and a void fraction is evaluated. Finally an axial void fraction distribution is evaluated based on the value of (az/ao) and the correlation curve.
摘要翻译：表示为第一参考强度A _{的第一强度A _{z > o 表示为第二强度B SUB表达的第二强度B 作为Bζz z x x x x x are are are are are，，，，evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated evaluated 。第一强度和第一参考强度是由重核素或裂变产物核素的中子捕获反应产生的放射性核素。第二强度和第二参考强度是放射性裂变产物核素，除了由中子俘获反应产生的核素外。在已知空隙率的情况下测量参考强度。此外，还评估了（a z> / / o o o o）和空隙率的相关曲线。最后，基于（a 1 / z 2 / a 2）的值和相关曲线来评估轴向空隙率分布。}}

10. 发明授权

US07171666B2 Processor module for a multiprocessor system and task allocation method thereof 失效
标题翻译：多处理器系统的处理器模块及其任务分配方法
公开(公告)号：US07171666B2
公开(公告)日：2007-01-30
申请号：US09682188
申请日：2001-08-02
申请人： Makoto Ueda
发明人： Makoto Ueda
IPC分类号： G06F9/46 , G06F12/00
CPC分类号： G06F9/5033
摘要： A multiprocessor system includes a plurality of processor modules having a detector for detecting accesses by respective tasks to data shared among cache memories in the processor modules. Also included is a storage device for storing an address of the shared data, identification information of the tasks that accessed the shared data, and the number of accesses to the same shared data by the same task.
摘要翻译：多处理器系统包括多个处理器模块，其具有检测器，用于检测各个任务对处理器模块中的高速缓冲存储器之间共享的数据的访问。还包括用于存储共享数据的地址，访问共享数据的任务的标识信息以及通过相同任务访问相同共享数据的数量的存储装置。

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