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    • 10. 发明申请
    • AGENT FOR THE TREATMENT OF ALOPECIA
    • 治疗ALOPECIA的代理
    • US20140315810A1
    • 2014-10-23
    • US14254938
    • 2014-04-17
    • Yori EndoKyoko EndoIGISU Co., Ltd.
    • Kyoko Endo
    • A61K38/22A61K45/06
    • A61K38/22A61K8/64A61K9/0014A61K31/14A61K31/506A61K31/573A61K31/7036A61K45/06A61Q7/00A61K2300/00
    • It is an object of the present invention to provide a new agent for the treatment of alopecia, the agent being not only effective and safe for, in particular, alopecia areata, androgenetic alopecia in a male, androgenetic alopecia in a female, female pattern alopecia, postpartum alopecia, seborrheic alopecia, alopecia pityroides, senile alopecia, cancer chemotherapy drug-induced alopecia, and alopecia due to radiation exposure, but also effective for a target having resistance to treatment with minoxidil or finasteride, there being no side effects such as an itching sensation, irritation, or feminization, and no contraindications, the agent suppressing dandruff or having a therapeutic effect for white hair, and the therapeutic effect for alopecia being maintained for a long period even when use of the agent is stopped.The solution means of the present invention is an agent for the treatment of alopecia containing as an active ingredient a C-type natriuretic peptide (CNP), a B-type natriuretic peptide (BNP), a derivative of these NPs, a chimeric peptide of these NPs, or a derivative of a chimeric peptide of these NPs.
    • 本发明的目的是提供一种治疗脱发的新药物,该药物不仅对于特别是斑秃病有效和安全,雄性雄激素性脱发,女性雄性发育性脱发,女性型脱发 ,产后脱发,脂溢性脱发,脱发性脱发,老年脱发,癌症化疗药物性脱发,以及由于放射线暴露引起的秃发,对于具有抗美西尼地或非那雄胺治疗的靶标也有效,不存在副作用 瘙痒感,刺激或女性化,无禁忌症,抑制头皮屑或对白发具有治疗作用的药剂,并且即使停止使用药剂,长时间保持秃发的治疗效果。 本发明的解决方案是用于治疗含有作为活性成分的C型利尿钠肽(CNP),B型利尿钠肽(BNP),这些NP的衍生物的秃发症的药剂, 这些NP,或这些NP的嵌合肽的衍生物。