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    • 3. 发明申请
    • APPARATUS AND METHODS FOR LIMITING PRESSURE AND FLOW WITHIN A MEDICAL INJECTOR
    • 用于限制医用注射器内的压力和流量的装置和方法
    • US20120259313A1
    • 2012-10-11
    • US13500500
    • 2010-12-14
    • John F. KrummeScott Heneveld
    • John F. KrummeScott Heneveld
    • A61M5/34
    • A61M5/24A61M5/20A61M5/3134A61M5/34A61M5/488A61M39/22A61M2005/2488A61M2005/2492A61M2005/3128A61M2205/14
    • A medical injector (200) includes a medicament container (210) including a main lumen (214) and a reduced-diameter protrusion (220), a needle assembly (230) coupled to the protrusion (220), and a flow control member (250). The medicament container (210) is configured to contain a medicament, such as, for example, a dermal filler. The flow control member (250) is disposed within the protrusion (220) of the medicament container (210), and includes a flow control lumen (254) configured to control a pressure or a flow of the medicament. Thus, the flow control member (250) reduces decoupling forces applied to the needle assembly (230) by the flow of medicament. Alternatively, the flow control member (250) may move from a first position allowing flow from the main lumen (214) to the needle assembly (230) to a second position blocking flow from the medicament container (210) when the needle assembly (230) decouples from the protrusion (220).
    • 医疗注射器(200)包括药物容器(210),其包括主腔(214)和缩径直径突起(220),联接到突起(220)的针组件(230)和流动控制构件 250)。 药物容器(210)构造成容纳药物,例如皮肤填充剂。 流量控制构件(250)设置在药物容器(210)的突出部(220)内,并且包括配置成控制药物的压力或流动的流动控制腔(254)。 因此,流动控制构件(250)通过药物流减小施加到针组件(230)的去耦力。 或者,流动控制构件(250)可以从第一位置移动,允许从主腔(214)到针组件(230)的流动到针组件(230)处阻止从药物容器(210)流动的第二位置 )与突起(220)分离。
    • 4. 发明授权
    • Eyeglasses
    • 眼镜
    • US09086581B2
    • 2015-07-21
    • US13668730
    • 2012-11-05
    • Robert B. ZiderJohn F. KrummeBrian A. Thompson
    • Robert B. ZiderJohn F. KrummeBrian A. Thompson
    • G02C1/02G02C1/08
    • G02C1/023G02C1/02G02C1/06G02C1/08G02C1/10G02C5/00G02C13/001
    • Eyeglass assemblies including an eyeglass lens having an engaging portion. Under typical conditions of use, the engaging portion is maintained in contact with an eyeglass frame member by means of a removable bonding member (RBM). Under selected atypical ambient conditions, the RBM changes so that the engaging portion and the frame member can be separated. The engaging portion can extend from the lens, or can be a recess in the lens. The RBM can be a suitable adhesive (RBA), or a component composed of a shape memory metal (RBSMA) or a material which softens when subjected to heat or other atypical condition. The engaging portion can be shaped and treated to reduce stresses therein. Similarly, the open ends of an eyeglass rim can be maintained in contact with each other under typical conditions of use by an RBA or an RBSMA so that the rim is positioned around an eyeglass lens, but can be released under selected atypical ambient conditions.
    • 眼镜组件包括具有接合部分的眼镜镜片。 在典型的使用条件下,接合部分通过可拆卸接合部件(RBM)与眼镜框架部件保持接触。 在选择的非典型环境条件下,RBM改变,使得接合部分和框架构件可以分离。 接合部分可以从透镜延伸,或者可以是透镜中的凹部。 RBM可以是合适的粘合剂(RBA)或由形状记忆金属(RBSMA)组成的组分或当经受热或其它非典型条件时软化的材料。 接合部分可以被成形和处理以减小其中的应力。 类似地,眼镜边缘的开口端可以在典型的RBA或RBSMA使用条件下保持彼此接触,使得边缘位于眼镜镜片周围,但可以在选定的非典型环境条件下释放。
    • 6. 发明授权
    • Over-current/over-temperature protection device
    • 过电流/过温保护装置
    • US5438309A
    • 1995-08-01
    • US133187
    • 1993-10-19
    • John F. Krumme
    • John F. Krumme
    • H01H1/50H01H61/01H01R4/01H01H61/06
    • H01H61/0107H01R4/01H01H1/504
    • An over-current/over-temperature protection device (1) which includes first and second electrical contacts (2,3), a separable resistance electrical current path (4) extending between the contacts, a breaker (6) and a heater. The heater comprises the separable path (4). The breaker breaks an electrical connection between at least one of the contacts and the separable path when current above a threshold value passes through the separable path and/or the over-current/over-temperature protection device reaches a threshold temperature. The breaker (6) includes a member of a shape memory alloy which changes shape from a first configuration to a second configuration when the member is heated from a first temperature T.sub.1 to a second temperature T.sub.2. The heater heats the member from the first temperature T.sub.1 to the second temperature T.sub.2 so that the member changes from the first configuration to the second configuration. The device can optionally include a permanent resistance electrical current path (5) having a resistance higher than the separable path (4). The device can also include a button (110) for resetting the device or a control circuit for remotely completing or breaking the electrical connection between the separable path and the contacts.
    • PCT No.PCT / US92 / 01185 Sec。 371日期:1993年10月19日 102(e)日期1993年10月19日PCT提交1992年2月19日PCT公布。 WO92 / 19002 PCT出版物 日期:1992年10月29日。一种过电流/过温保护装置(1),其包括第一和第二电触头(2,3),在触头之间延伸的可分离电阻电流通路(4),断路器 6)和加热器。 加热器包括可分离路径(4)。 当超过阈值的电流通过可分离路径和/或过电流/过温保护装置达到阈值温度时,断路器断开至少一个触点和可分离路径之间的电连接。 断路器(6)包括形状记忆合金的构件,当构件从第一温度T1加热到第二温度T2时,形状记忆合金的形状从第一构型改变到第二构型。 加热器将构件从第一温度T1加热到第二温度T2,使得构件从第一构型变化到第二构造。 该装置可以可选地包括具有高于可分离路径(4)的电阻的永久电阻电流路径(5)。 该装置还可以包括用于复位装置的按钮(110)或用于远程完成或破坏可分离路径和触点之间的电连接的控制电路。
    • 7. 发明授权
    • Intra-luminal expander assembly
    • 腔内扩张器组件
    • US5409460A
    • 1995-04-25
    • US48352
    • 1993-04-15
    • John F. Krumme
    • John F. Krumme
    • A61F2/82A61B17/00A61M29/00A61M25/00
    • A61M29/02A61B2017/00867
    • An intra-luminal expander assembly for use with a catheter comprises an expandable tubular expander element having openings, for example slots, formed in it, and first and second fixation portions located at or towards its ends. The expander element is disposed around a core element which comprises a shape memory alloy which has been treated so that, when the temperature of the alloy is increased above its A.sub.s temperature, it displays a shape memory effect and the length of the core element decreases. The expander element is attached to the core element through the first fixation portion and oriented so that, as the length of the core element decreases when its temperature increases, the first fixation portion is caused to move relative to the second fixation portion in a direction towards the second fixation portion, and the second fixation portion being restrained against movement with the first fixation portion so that the length of the expander element decreases and its transverse dimension increases.
    • 与导管一起使用的腔内扩张器组件包括具有开口的可膨胀管状膨胀器元件,例如形成在其中的槽,以及位于或朝向其端部的第一和第二固定部分。 膨胀机元件围绕芯元件设置,该芯元件包括形状记忆合金,其已经被处理,使得当合金的温度升高到高于其As温度时,其显示形状记忆效应并且芯元件的长度减小。 膨胀元件通过第一固定部分附接到芯元件并且被定向成使得当芯元件的温度升高时,芯元件的长度减小,使得第一固定部分相对于第二固定部分朝向 第二固定部分和第二固定部分被限制与第一固定部分的运动,使得膨胀器元件的长度减小并且其横向尺寸增大。
    • 8. 发明授权
    • Over-current/over-temperature protection device
    • 过电流/过温保护装置
    • US5105178A
    • 1992-04-14
    • US687792
    • 1991-04-19
    • John F. Krumme
    • John F. Krumme
    • H01H1/50H01H61/01H01R4/01
    • H01H61/0107H01R4/01H01H1/504
    • An over-current/over-temperature protection device which includes first and second electrical contacts, a separable resistance electrical separable path extending between the contacts, a breaker means and a heater. The heater comprises the separable path. The breaker breaks an electrical connection between at least one of the contacts and the separable path when current above a threshold value passes through the separable path and/or the over-current/over-temperature protection device reaches a threshold temperature. The breaker includes a member of a shape memory alloy which changes shape from a first configuration to a second configuration when the member is heated from a first temperature T.sub.1 to a second temperature T.sub.2. The heater heats the member from the first temperature T.sub.1 to the second temperature T.sub.2 so that the member changes from the first configuration to the second configuration. The over-current/over-temperature protection device can include a spring for changing the member into the first configuration when the member cools from the second temperature T.sub.2 to a temperature T.sub.3 below T.sub.2. The over-current/over-temperature protection device can include a permanent resistance electrical current path having a resistance higher than the separable path. The permanent path minimizes arcing when the electrical connection between the separable path and at least one of the contacts is broken by the breaker.
    • 一种过电流/过温保护装置,其包括第一和第二电触头,在触头之间延伸的可分离的电阻分离路径,断路器装置和加热器。 加热器包括可分离路径。 当超过阈值的电流通过可分离路径和/或过电流/过温保护装置达到阈值温度时,断路器断开至少一个触点和可分离路径之间的电连接。 断路器包括形状记忆合金的构件,当构件从第一温度T1加热到第二温度T2时,形状记忆合金的形状从第一构型改变到第二构型。 加热器将构件从第一温度T1加热到第二温度T2,使得构件从第一构型变化到第二构造。 过电流/过温保护装置可以包括弹簧,用于当构件从第二温度T2冷却到低于T2的温度T3时,将构件改变成第一构型。 过电流/过温保护装置可以包括具有高于可分离路径的电阻的永久电阻电流路径。 当可分离路径和至少一个触点之间的电连接被断路器断开时,永久路径使电弧放电最小化。
    • 9. 发明授权
    • Fluid delivery apparatus with shape-memory flow control element
    • 具有形状记忆流量控制元件的流体输送装置
    • US4645489A
    • 1987-02-24
    • US733036
    • 1985-04-29
    • John F. KrummeDarel E. Hodgson
    • John F. KrummeDarel E. Hodgson
    • A61M5/168A61M39/28A61M5/00
    • A61M39/285A61M5/16813
    • A unitary disposable conduit extends from the intravenous reservoir along a gravity-flow path to the patient, and incorporates a valve block containing an externally controlled flow-control valve. An electronic controller monitors the drop rate in a drop chamber which is an integral part of the disposable conduit, compares this rate with an operator-selected rate, and controls the valve by varying the current in a shape-memory actuator element whose movements, caused by the resultant Joule heating, are coupled to the valve to proportionally vary the flow rate in the conduit. The valve block is securely received within a recess in the controller, and is automatically coupled to the controller when inserted within this recess. The shape-memory actuator element may be incorporated within the disposable valve block, or may form a part of the controller, with a simple mechanical coupling to transmit its movements to the valve. The valve may be automatically or manually closed when the valve block is removed from the controller, or if power failure occurs.
    • 一体式一次性导管从静脉内容器沿着重力流动路径延伸到患者身上,并且包括一个包含外部控制的流量控制阀的阀块。 电子控制器监测作为一次性导管的组成部分的液滴室中的液滴速率,将该速率与操作者选择的速率进行比较,并且通过改变形状记忆致动器元件中的电流来控制阀门,该形状记忆致动器元件的运动导致 通过所产生的焦耳加热,联接到阀以成比例地改变管道中的流速。 阀块牢固地容纳在控制器的凹槽中,并且当插入该凹槽内时自动地连接到控制器。 形状记忆致动器元件可以结合在一次性阀块内,或者可以形成控制器的一部分,具有简单的机械联接以将其运动传递到阀。 当阀门从控制器上拆下或发生停电时,阀门可以自动或手动关闭。
    • 10. 发明授权
    • Alternating current electrically resistive heating element having
intrinsic temperature control
    • 具有固有温度控制的交流电阻加热元件
    • US4256945A
    • 1981-03-17
    • US71682
    • 1979-08-31
    • Philip S. CarterJohn F. Krumme
    • Philip S. CarterJohn F. Krumme
    • H05B3/12H05B3/42H05B6/10H05B5/00
    • H05B3/42H05B3/12
    • The heating element consists of a substrate or core of a non-magnetic material having high thermal and electrical conductivity, clad with a surface layer of a ferromagnetic material of relatively low electrical conductivity. When the heating element is energized by a source of high frequency alternating current, the skin effect initially confines current flow principally to the surface layer of ferromagnetic material. As temperature rises into the region of the Curie temperature of the ferromagnetic material, however, the decline in magnetic permeability of the ferromagnetic material causes a significant lessening of the skin effect, permitting migration of current into the high conductivity non-magnetic core, thereby simultaneously enlarging the cross-sectional area of the current flow path and expanding it into the highly conductive material; the resistance of the heating element becomes less due to both causes. By selecting the proper frequency for energization, by regulating the source to produce constant current, and by selecting dimensions and material parameters for the heating element, temperature regulation in a narrow range around the Curie temperature of the ferromagnetic material can be produced, despite considerable fluctuations in thermal load.
    • 加热元件由具有高导热性和导电性的非磁性材料的基底或芯组成,其具有相对低导电性的铁磁材料的表面层。 当加热元件被高频交流电源通电时,皮肤效应首先将电流主要限制在铁磁材料的表面层上。 然而,当温度上升到铁磁材料的居里温度区域时,铁磁材料的磁导率的下降导致皮肤效应的显着减小,从而允许电流迁移到高导电率非磁性芯中,从而同时 扩大电流流路的横截面积并将其膨胀成高导电材料; 由于这两个原因,加热元件的电阻变小。 通过选择适当的通电频率,通过调节源来产生恒定电流,并通过选择加热元件的尺寸和材料参数,尽管有相当大的波动,但可以产生在铁磁材料居里温度附近的窄范围内的温度调节 在热负荷。