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1. 发明申请

US20060020331A1 Coated medical device 有权
标题翻译：涂层医疗器械
公开(公告)号：US20060020331A1
公开(公告)日：2006-01-26
申请号：US11234702
申请日：2005-09-23
申请人： Brian Bates , Scott Boatman , David Burton , Michael Hoffa , Darin Schaeffer , Jason Sturgeon , Anthony Ragheb
发明人： Brian Bates , Scott Boatman , David Burton , Michael Hoffa , Darin Schaeffer , Jason Sturgeon , Anthony Ragheb
IPC分类号： A61F2/06
CPC分类号： A61M25/10 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/958 , A61F2210/0014 , A61F2210/0076 , A61F2240/001 , A61F2250/0025 , A61F2250/0026 , A61F2250/0067 , A61F2250/0081 , A61F2250/0098 , A61F2310/00011 , A61L27/54 , A61L29/08 , A61L29/085 , A61L29/16 , A61L29/18 , A61L31/14 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61L2400/18 , A61L2420/02 , A61L2420/06 , A61M25/1029 , A61M25/104 , A61M2025/1031 , A61M2025/105 , A61M2250/00
摘要： A coated medical device adapted for introduction into a passage or vessel of a patient is provided. The medical device is preferably an implantable balloon with a bioactive deposited or within the balloon. The balloon can further include a hydrophilic material positioned between the balloon and a bioactive material posited on the balloon.
摘要翻译：提供适于引入患者的通道或容器中的涂覆医疗装置。医疗装置优选地是具有生物活性沉积的或在球囊内的可植入气球。球囊可以进一步包括位于球囊和放置在球囊上的生物活性物质之间的亲水材料。

2. 发明申请

US20050171597A1 Helical stent for branched vessel prosthesis 审中-公开
标题翻译：支气管假体螺旋支架
公开(公告)号：US20050171597A1
公开(公告)日：2005-08-04
申请号：US10984131
申请日：2004-11-08
申请人： Scott Boatman , Darin Schaeffer , Michael Hoffa
发明人： Scott Boatman , Darin Schaeffer , Michael Hoffa
IPC分类号： A61B17/11 , A61F2/00 , A61F2/06 , A61F2/82 , A61F2/88
CPC分类号： A61F2/954 , A61B2017/1107 , A61B2017/1139 , A61F2/064 , A61F2/07 , A61F2/856 , A61F2/88 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/821 , A61F2002/8483 , A61F2002/8486 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/9511 , A61F2210/0076 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2220/0083 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0078 , A61F2250/0018 , A61F2250/0039 , A61F2250/0097 , A61F2250/0098
摘要： A branch vessel prosthesis is provided for use with an aorta stent graft defining a lumen and having a fenestration aligned with a branch vessel, including a generally helical coiled stent, preferably with a graft material affixed thereto to form a branch vessel lumen. At least one full turn at the proximal end of the helical coiled stent has a diameter larger than the diameter of the fenestration so as to retain the proximal end within the aorta stent. At least two full turns of the helical coil have a diameter smaller than the at least one full coil so as to pass through the fenestration upon deployment.
摘要翻译：分支血管假体被提供用于与主动脉支架移植物一起使用，所述主动脉支架移植物限定内腔并具有与分支血管对齐的开窗，所述开口包括大致螺旋卷曲的支架，优选地具有固定到其上的移植材料以形成分支血管腔。在螺旋盘绕支架的近端处的至少一整圈具有大于开窗直径的直径，以将近端保持在主动脉支架内。螺旋线圈的至少两个完整匝的直径小于至少一个完整线圈的直径，以便在展开时通过开窗。

3. 发明申请

US20080046063A1 Stent Deployment Device 有权
标题翻译：支架部署装置
公开(公告)号：US20080046063A1
公开(公告)日：2008-02-21
申请号：US11547020
申请日：2005-03-22
申请人： Scott Boatman , Michael Hoffa , Kimberly Roberts , Darin Schaeffer
发明人： Scott Boatman , Michael Hoffa , Kimberly Roberts , Darin Schaeffer
IPC分类号： A61F2/84
CPC分类号： A61F2/958 , A61F2002/821
摘要： A stent deployment device (110) is provided for deploying a stent in a lumen of a patient. The device can include a catheter (112), a first balloon (122) positioned near a distal end of the catheter and a second balloon (123) adjacent to the first balloon. Alternatively, the second balloon can be positioned over the first balloon. The device also includes an expandable stent (210) positioned over the first balloon and the second balloon. The first balloon comprises a semi-compliant material, a noncompliant material or a compliant material. Similarly, the second balloon comprises a semi-compliant material, a noncompliant material or a compliant material. The first balloon is expandable to a first diameter, while the second balloon can be expandable to a second diameter.
摘要翻译：提供支架展开装置（110）用于将支架展开在患者的内腔中。该装置可以包括导管（112），定位在导管的远端附近的第一球囊（122）和邻近第一球囊的第二球囊（123）。或者，第二气球可以位于第一气球上方。该装置还包括位于第一球囊和第二球囊之上的可扩张支架（210）。第一气囊包括半柔顺材料，不符合材料或柔顺材料。类似地，第二气囊包括半柔顺材料，不合格材料或顺应性材料。第一气囊可扩张至第一直径，而第二球囊可扩张至第二直径。

4. 发明申请

US20060058864A1 Balloon flareable branch vessel prosthesis and method 有权
公开(公告)号：US20060058864A1
公开(公告)日：2006-03-16
申请号：US10984417
申请日：2004-11-08
申请人： Darin Schaeffer , Michael Hoffa , Scott Boatman , Kim Roberts
发明人： Darin Schaeffer , Michael Hoffa , Scott Boatman , Kim Roberts
IPC分类号： A61F2/06
CPC分类号： A61F2/954 , A61B2017/1107 , A61B2017/1139 , A61F2/064 , A61F2/07 , A61F2/856 , A61F2/88 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/821 , A61F2002/8483 , A61F2002/8486 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/9511 , A61F2210/0076 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2220/0083 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0078 , A61F2250/0018 , A61F2250/0039 , A61F2250/0097 , A61F2250/0098
摘要： A stent graft system for intraluminal deployment in an aorta and a branch vessel that includes an aorta stent graft for deployment within the aorta and defining a lumen for the passage of blood therethrough, and having a fenestration positioned and sized so as to allow blood to flow to a contiguous branch vessel. The system also includes a branch vessel prosthesis, preferably a stent graft, having a tubular portion and a flaring portion, such that, when deployed, the flaring portion is located within the lumen of the aorta stent graft and the tubular portion passes through the fenestration and into the branch vessel. A balloon expansion catheter expands the tubular portion and flare the flaring portion. The expansion of the tubular portion and the flaring of the flaring portion may occur sequentially or simultaneously.

5. 发明申请

US20050222668A1 Flareable branch vessel prosthesis and method 有权
标题翻译：可扩张分支血管假体和方法
公开(公告)号：US20050222668A1
公开(公告)日：2005-10-06
申请号：US10984520
申请日：2004-11-08
申请人： Darin Schaeffer , Michael Hoffa
发明人： Darin Schaeffer , Michael Hoffa
IPC分类号： A61B17/11 , A61F2/00 , A61F2/06 , A61F2/82 , A61F2/88
CPC分类号： A61F2/954 , A61B2017/1107 , A61B2017/1139 , A61F2/064 , A61F2/07 , A61F2/856 , A61F2/88 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/821 , A61F2002/8483 , A61F2002/8486 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/9511 , A61F2210/0076 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2220/0083 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0078 , A61F2250/0018 , A61F2250/0039 , A61F2250/0097 , A61F2250/0098
摘要： A branch vessel prosthesis for use with an aorta stent graft defining a lumen and having a fenestration aligned with a branch vessel, includes an expandable stent that has a tubular portion, a flareable portion, and at least one bending portion located between the tubular and the flareable portions. Upon deployment of the branch vessel prosthesis, the flareable portion is flared by bending of the bending portion.
摘要翻译：一种用于与限定内腔并具有与分支血管对准的开窗的主动脉支架移植物一起使用的分支血管假体，包括可扩张支架，其具有管状部分，可扩张部分和至少一个弯曲部分，位于管状部分和第可爆部分在展开分支血管假体时，通过弯曲部分的弯曲来扩张可扩张部分。

6. 发明申请

US20050154441A1 Introducer 审中-公开
标题翻译：介绍人
公开(公告)号：US20050154441A1
公开(公告)日：2005-07-14
申请号：US10756851
申请日：2004-01-14
申请人： Darin Schaeffer , Michael Hoffa
发明人： Darin Schaeffer , Michael Hoffa
IPC分类号： A61F2/06 , A61F2/84 , A61M25/06
CPC分类号： A61M25/06 , A61F2/958
摘要： A stent introducer is provided for introducing a stented catheter through a hemostatic valve. The stent introducer is inserted into the hemostatic valve to open the valve member and provide an open passageway for the stented catheter. The stent introducer is made from flexible plastic and has a slot that extends along the entire length of the stent introducer. Advantages of the stent introducer include ease of use and improved protection for the stented catheter during introduction.
摘要翻译：提供了一种支架导引器，用于通过止血阀引入支架置入的导管。将支架导入器插入止血阀中以打开阀构件并提供用于支架导管的开放通道。支架导引器由柔性塑料制成并且具有沿着支架引入器的整个长度延伸的狭槽。支架引入器的优点包括易于使用，并且在引入期间改进了支架导管的保护。

7. 发明申请

US20050149166A1 Branch vessel prosthesis with anchoring device and method 审中-公开
标题翻译：具有锚固装置和方法的分支血管假体
公开(公告)号：US20050149166A1
公开(公告)日：2005-07-07
申请号：US10984167
申请日：2004-11-08
申请人： Darin Schaeffer , Michael Hoffa
发明人： Darin Schaeffer , Michael Hoffa
IPC分类号： A61B17/11 , A61F2/00 , A61F2/06 , A61F2/82 , A61F2/88
CPC分类号： A61F2/954 , A61B2017/1107 , A61B2017/1139 , A61F2/064 , A61F2/07 , A61F2/856 , A61F2/88 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/821 , A61F2002/8483 , A61F2002/8486 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/9511 , A61F2210/0076 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2220/0083 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0078 , A61F2250/0018 , A61F2250/0039 , A61F2250/0097 , A61F2250/0098
摘要： A stent graft system for intraluminal deployment in an aorta and a branch vessel includes an aorta stent graft for deployment within an aorta and defining a lumen for the passage of blood therethrough, and having a fenestration aligned so as to allow blood to flow to a contiguous branch vessel. A branch vessel prosthesis having a flaring portion, a tubular portion and an anchoring device, are configured so that, upon deployment, the tubular portion passes through the fenestration and into the branch vessel, the anchoring device affixes the position of the tubular portion within the branch vessel, and the flaring portion is retained within the lumen of the aorta stent graft and is maintained against an inside wall of the aorta stent graft to thereby bias the aorta stent graft toward the branch vessel.
摘要翻译：用于腔内部署在主动脉和分支血管中的支架移植系统包括主动脉支架移植物，用于展开在主动脉内并且限定用于血液通过的管腔，并且具有对齐的开窗，以允许血液流动到连续的分支船。具有扩口部分，管状部分和锚固装置的分支血管假体被构造成使得在展开时，管状部分穿过开窗并进入分支容器，锚定装置将管状部分的位置固定在分支血管，并且扩口部分保持在主动脉支架移植物的内腔内并且保持抵靠主动脉支架移植物的内壁，从而将主动脉支架移植物偏向分支血管。

8. 发明申请

US20060016064A1 Medical device including unitary, continuous portion of varying durometer 有权
标题翻译：医疗设备包括单位，连续部分变化的硬度
公开(公告)号：US20060016064A1
公开(公告)日：2006-01-26
申请号：US10813415
申请日：2004-03-30
申请人： Scott Boatman , David Burton , Michael Hoffa , Thomas Osborne , David Drewes , David Lessard , Maggie Hupcey
发明人： Scott Boatman , David Burton , Michael Hoffa , Thomas Osborne , David Drewes , David Lessard , Maggie Hupcey
IPC分类号： B29C47/20 , B29C35/08 , B21B1/46
CPC分类号： A61M25/0009 , A61L29/06 , B29C35/08 , B29K2077/00 , B29L2031/7542 , C08F283/04 , C08G69/48 , Y10T29/4998 , C08L77/00 , C08F218/16
摘要： A medical device (110) including a catheter shaft (111) and a unitarily and continuously formed portion (108) having a varying durometer, and optionally including an expandable balloon (18, 118). One or both of the unitarily and continuously formed portion (108) and the balloon (18, 118) are made from an irradiation cross-linked or cross-linkable mixture of a polyamide elastomer and at least one additional cross-linking reactant. The polyamide elastomer can be a polyester amide, a polyether ester amide or a polyether amide, and is preferably a nylon block copolymer. The aromatic molecule can be 1,3,5 triethyl benzene; 1,2,4 triethyl benzene; and 1,3,5 triisopropyl benzene. The cross-linking reactant can be: (a) a difunctional material, (b) a trifunctional material, (c) a tetrafunctional material, or (d) an aromatic molecule containing at least two ring substituents, each of the ring substituents having labile hydrogens at a benzylic site therein. The cross-linking reactant can also be diallyl phthalate or meta-phenylene dimaleimide.
摘要翻译：一种医疗装置（110），包括导管轴（111）和具有变化的硬度的整体连续形成部分（108），并且可选地包括可膨胀气囊（18,118）。整体和连续形成的部分（108）和球囊（18,118）中的一个或两个由聚酰胺弹性体和至少一种另外的交联反应物的照射交联或可交联混合物制成。聚酰胺弹性体可以是聚酯酰胺，聚醚酯酰胺或聚醚酰胺，优选为尼龙嵌段共聚物。芳族分子可以是1,3,5三乙基苯; 1,2,4三乙苯; 和1,3,5三异丙基苯。交联反应物可以是：（a）双官能材料，（b）三官能材料，（c）四官能材料，或（d）含有至少两个环取代基的芳族分子，每个环取代基具有不稳定性在其苄基位点处的氢。交联反应物也可以是邻苯二甲酸二烯丙酯或间亚苯基二马来酰亚胺。

9. 发明授权

US08280486B2 Site marker visable under multiple modalities 有权
标题翻译：站点标记在多种模式下可见
公开(公告)号：US08280486B2
公开(公告)日：2012-10-02
申请号：US11242334
申请日：2005-10-03
申请人： Michael E. Miller , Michael Hoffa , Joseph L. Mark , Zachary R. Nicoson
发明人： Michael E. Miller , Michael Hoffa , Joseph L. Mark , Zachary R. Nicoson
IPC分类号： A61B6/00
CPC分类号： A61B90/39 , A61B10/02 , A61B2017/00004 , A61B2017/00867 , A61B2090/3908 , A61B2090/3925 , A61B2090/3995
摘要： A site marker is provided that includes a generally hollow body defining a cavity. At least one marker element is captured within the cavity but is able to move within the cavity. The capturing prevents migration of the marker within a body. The site marker is formed into a predeployment configuration whereby the site marker is compressed into a predetermined size and shape to as to be readily positionable within a deployment device. The site marker expands from the predeployment position to a post deployment configuration upon insertion into the body.
摘要翻译：提供了一种位置标记，其包括限定空腔的大体中空的主体。至少一个标记元件被捕获在空腔内，但是能够在空腔内移动。捕获可防止标记在体内迁移。站点标记形成为部署前配置，由此站点标记被压缩成预定尺寸和形状以便容易地定位在展开装置内。插入身体后，站点标记将从部署前位置展开为后部署配置。

10. 发明授权

US08554309B2 Localizing obturator with site marking capability 有权
标题翻译：本地化闭塞器具有现场标记能力
公开(公告)号：US08554309B2
公开(公告)日：2013-10-08
申请号：US12888641
申请日：2010-09-23
申请人： Michael Hoffa
发明人： Michael Hoffa
IPC分类号： A61B5/00
CPC分类号： A61B10/0275 , A61B17/3468 , A61B90/39 , A61B2017/00004 , A61B2017/3411 , A61B2090/034 , A61B2090/3908 , A61B2090/3925 , A61B2090/3954 , A61B2090/3966 , A61B2090/3987 , A61B2090/3995 , A61B2217/005
摘要： A target localizing and marking device is provided including a cannula having proximal and distal ends and a lumen therebetween, and a tip member releasably attached to the distal end, where the tip member includes and outer shell and at least one inner chamber. The device further includes at least one image enhancing component disposed on the outer shell and/or within the at least one inner chamber, at least one marking component disposed in the at least one inner chamber, and a tip member deployment mechanism. The deployment mechanism has a manually engageable actuator, a portion of which is dimensioned to slidably pass through the lumen of the cannula, and is operable to separate the tip member from the cannula and deploy the tip member to a predetermined target site. In some implementations, the device is magnetic resonance imaging (MRI) compatible and is identifiable under MRI.
摘要翻译：提供了一种目标定位和标记装置，其包括具有近端和远端以及其间的管腔的插管，以及可释放地附接到远端的尖端构件，其中尖端构件包括外壳和至少一个内室。该装置还包括设置在外壳和/或至少一个内室内的至少一个图像增强部件，设置在至少一个内室中的至少一个标记部件和尖端部件展开机构。展开机构具有可手动接合的致动器，其一部分的尺寸设计成可滑动地穿过套管的内腔，并且可操作以将尖端构件与插管分离并将尖端构件展开到预定的目标位置。在一些实施方案中，该装置是磁共振成像（MRI）兼容的，并且可以在MRI下识别。

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