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    • 8. 发明授权
    • Method for testing infectious disease causing microorganisms
    • 测定感染性疾病引起微生物的方法
    • US5876959A
    • 1999-03-02
    • US638851
    • 1996-04-29
    • Shin-ichiro KusunokiJun-ichiro Arai
    • Shin-ichiro KusunokiJun-ichiro Arai
    • C12M1/34C12Q1/04
    • C12Q1/04C12Q2304/44
    • A method for detecting, identifying and measuring infectious disease causing microorganisms is described. The method utilizes a plural medium arrangement in which a test liquid containing a microorganism is simultaneously introduced. Different media are utilized for the plural medium arrangement and at least one of the media can contain a respiration inhibiting material and/or other reagents such as antibiotics. Dissolved oxygen measurements of the media are taken as a measurement of microorganism respiration. Oxygen electrode signals within different media are compared and differential respiration variation rates are determined and identification signals produced. The identification signal resulting from the multiple respiration rate determinations is compared with known values to identify and measure the microorganism. The drug sensitivity of a microorganism is also judged when at least one of the media contains a drug for which the sensitivity of microorganism is to be determined.
    • 描述了用于检测,识别和测量引起感染性微生物的传染病的方法。 该方法利用了同时引入含有微生物的检测液的多种培养基配置。 不同的培养基用于多种培养基布置,并且至少一种培养基可以含有呼吸抑制材料和/或其它试剂如抗生素。 将介质的溶解氧测量作为微生物呼吸的测量值。 比较不同介质中的氧电极信号,确定差异呼吸变化率,产生识别信号。 将由多次呼吸速率测定得到的识别信号与已知值进行比较,以鉴定和测量微生物。 当至少一种培养基含有确定微生物敏感性的药物时,也判断微生物的药物敏感性。
    • 10. 发明授权
    • Infectious disease inspection method and apparatus therefor
    • 传染病检查方法及装置
    • US6143555A
    • 2000-11-07
    • US219930
    • 1998-12-23
    • Shin-ichiro KusunokiJun-ichiro Arai
    • Shin-ichiro KusunokiJun-ichiro Arai
    • C12M1/34C12Q1/00C12Q1/04C12M3/00
    • C12Q1/04C12Q1/001C12Q1/005C12Q2304/44Y10S435/81
    • An apparatus for detecting, identifying and measuring infectious disease causing microorganisms is described. The apparatus utilizes a plural medium arrangement in which a test liquid containing a microorganism is simultaneously introduced. Different media are utilized for the plural medium arrangement and at least one of the media can contain a respiration inhibiting material and/or other reagents such as antibiotics. Dissolved oxygen measurements of the media are taken as a measurement of microorganism respiration. Oxygen electrode signals within different media are compared and differential respiration variation rates are determined and identification signals produced. The identification signal resulting from the multiple respiration rate determinations is compared with known values to identify and measure the microorganism. The drug sensitivity of a microorganism is also judged when at least one of the media contains a drug for which the sensitivity of microorganism is to be determined.
    • 描述了用于检测,识别和测量引起感染性微生物的传染病的装置。 该装置利用其中同时引入含有微生物的测试液的多种介质装置。 不同的培养基用于多种培养基布置,并且至少一种培养基可以含有呼吸抑制材料和/或其它试剂如抗生素。 将介质的溶解氧测量作为微生物呼吸的测量值。 比较不同介质中的氧电极信号,确定差异呼吸变化率,产生识别信号。 将由多次呼吸速率测定得到的识别信号与已知值进行比较,以鉴定和测量微生物。 当至少一种培养基含有确定微生物敏感性的药物时,也判断微生物的药物敏感性。