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1. 发明授权

US5897495A Ultrasonic wave medical treatment apparatus suitable for use under guidance of magnetic resonance imaging 失效
标题翻译：超声波医疗器械适用于磁共振成像引导下使用
公开(公告)号：US5897495A
公开(公告)日：1999-04-27
申请号：US727036
申请日：1996-10-08
申请人： Satoshi Aida , Mariko Shibata , Katsuhiko Fujimoto , Yoshiharu Ishibashi , Takuji Suzuki , Yasutoshi Ishihara , Kazuya Okamoto
发明人： Satoshi Aida , Mariko Shibata , Katsuhiko Fujimoto , Yoshiharu Ishibashi , Takuji Suzuki , Yasutoshi Ishihara , Kazuya Okamoto
IPC分类号： A61B5/055 , A61B18/00 , A61B19/00 , A61F7/00 , A61N7/02 , G01R33/28
CPC分类号： A61N7/022 , A61N7/02 , G01R33/28 , A61B2090/374
摘要： An ultrasonic wave medical treatment apparatus capable of preventing the displacement of the focal point of the ultrasonic waves from the treatment target portion within the patient, eliminating a need for re-positioning of the ultrasonic wave applicator with respect to the patient, and taking MR images to be utilized during the treatment at a high resolution. In this apparatus, the ultrasonic wave applicator can be integrally incorporated within a treatment table for carrying the patient into the MRI gantry for taking the MR images. The surface coil for taking the MR images can be provided on a surface film of a water bag in the ultrasonic wave applicator, or on a body cavity probe on which the ultrasonic transducer is also provided. The mixing rate of the coupling fluid can be adjusted, and the impedance matching between the ultrasonic transducer and the driving circuit can be maintained by minimizing the reflected electric power from the ultrasonic transducer.
摘要翻译：一种超声波医疗处理装置，其能够防止超声波的焦点从患者体内的治疗对象部位移位，消除了超声波施加器相对于患者重新定位的需要，并且取MR图像以高分辨率在治疗期间使用。在该装置中，超声波施加器可以整体地结合在处理台内，用于将病人携带到用于拍摄MR图像的MRI台架中。用于拍摄MR图像的表面线圈可以设置在超声波施加器中的水袋的表面膜上，也可以设置在也设置有超声波换能器的体腔探针上。可以调节耦合流体的混合速率，并且可以通过使来自超声换能器的反射电力最小化来维持超声换能器与驱动电路之间的阻抗匹配。

2. 发明授权

US5590653A Ultrasonic wave medical treatment apparatus suitable for use under guidance of magnetic resonance imaging 失效
标题翻译：超声波医疗器械适用于磁共振成像引导下使用
公开(公告)号：US5590653A
公开(公告)日：1997-01-07
申请号：US207670
申请日：1994-03-09
申请人： Satoshi Aida , Mariko Shibata , Katsuhiko Fujimoto , Yoshiharu Ishibashi , Takuji Suzuki , Yasutoshi Ishihara , Kazuya Okamoto
发明人： Satoshi Aida , Mariko Shibata , Katsuhiko Fujimoto , Yoshiharu Ishibashi , Takuji Suzuki , Yasutoshi Ishihara , Kazuya Okamoto
IPC分类号： A61B5/055 , A61B18/00 , A61B19/00 , A61F7/00 , A61N7/02 , G01R33/28
CPC分类号： A61N7/022 , A61N7/02 , G01R33/28 , A61B2090/374
摘要： An ultrasonic wave medical treatment apparatus capable of preventing the displacement of the focal point of the ultrasonic waves from the treatment target portion within the patient, eliminating a need for re-positioning of the ultrasonic wave applicator with respect to the patient, and taking MR images to be utilized during the treatment at a high resolution. In this apparatus, the ultrasonic wave applicator can be integrally incorporated within a treatment table for carrying the patient into the MRI gantry for taking the MR images. The surface coil for taking the MR images can be provided on a surface film of a water bag in the ultrasonic wave applicator, or on a body cavity probe on which the ultrasonic transducer is also provided. The mixing rate of the coupling fluid can be adjusted, and the impedance matching between the ultrasonic transducer and the driving circuit can be maintained by minimizing the reflected electric power from the ultrasonic transducer.
摘要翻译：一种超声波医疗处理装置，其能够防止超声波的焦点从患者体内的治疗对象部位移位，消除了超声波施加器相对于患者重新定位的需要，并且取MR图像以高分辨率在治疗期间使用。在该装置中，超声波施加器可以整体地结合在处理台内，用于将病人携带到用于拍摄MR图像的MRI台架中。用于拍摄MR图像的表面线圈可以设置在超声波施加器中的水袋的表面膜上，也可以设置在也设置有超声波换能器的体腔探针上。可以调节耦合流体的混合速率，并且可以通过使来自超声换能器的反射电力最小化来维持超声换能器与驱动电路之间的阻抗匹配。

3. 发明授权

US5694936A Ultrasonic apparatus for thermotherapy with variable frequency for suppressing cavitation 失效
标题翻译：用于抑制空化的具有可变频率的热疗的超声波装置
公开(公告)号：US5694936A
公开(公告)日：1997-12-09
申请号：US528263
申请日：1995-09-14
申请人： Katsuhiko Fujimoto , Yoshiharu Ishibashi , Mariko Shibata , Takuji Suzuki , Satoshi Aida , Shiroh Saitoh , Kazuya Okamoto
发明人： Katsuhiko Fujimoto , Yoshiharu Ishibashi , Mariko Shibata , Takuji Suzuki , Satoshi Aida , Shiroh Saitoh , Kazuya Okamoto
IPC分类号： A61B17/00 , A61B17/22 , A61N7/00 , A61N7/02
CPC分类号： A61N7/02 , A61B2017/00176 , A61B2017/22009 , A61N2007/0065 , A61N2007/0073
摘要： An ultrasonic diagnosis apparatus for raising tissue temperature for hypothermic treatments, including an ultrasonic source for generating an ultrasonic treatment wave and a driving means for driving the ultrasonic source such that a frequency of the ultrasonic treatment wave generated by the ultrasonic source changes with time. The frequency of the ultrasonic treatment wave is changed along the time axis. By this change in frequency, some bubbles formed by cavitation as a result of the ultrasonic treatment wave are divided, and some bubbles are collapsed and therefore eliminated. Side effect cavitation and spread of a thermal degeneration area is suppressed, and thermal degeneration can be accurately induced in a desired area, thereby realizing a reliable, safe ultrasonic thermotherapy. Since cavitation is positively suppressed, the total treatment period can be shortened because cavitation would otherwise interfere with and slow down the thermal degeneration process. Therefore, treatment throughput can be improved as compared with a case in which cavitation is left to naturally break and disappear.
摘要翻译：一种用于提高低温治疗的组织温度的超声波诊断装置，包括用于产生超声波处理波的超声波源和用于驱动超声波源的驱动装置，使得由超声波源产生的超声波处理波的频率随时间而变化。超声波处理波的频率沿时间轴变化。通过这种频率变化，由于超声波处理波而产生的由空穴形成的一些气泡被分割，并且一些气泡被折叠并因此被消除。抑制热变性区域的副作用空化和扩散，可以在期望的区域中精确地诱导热变性，从而实现可靠，安全的超声波热疗。由于气穴被积极地抑制，所以总处理时间可以缩短，因为空化会妨碍和减慢热变性过程。因此，与空穴自然断裂和消失的情况相比，能够提高处理量。

4. 发明授权

US5722411A Ultrasound medical treatment apparatus with reduction of noise due to treatment ultrasound irradiation at ultrasound imaging device 失效
标题翻译：超声波治疗装置，超声波成像装置处理超声波照射引起的噪声降低
公开(公告)号：US5722411A
公开(公告)日：1998-03-03
申请号：US681451
申请日：1996-07-23
申请人： Takuji Suzuki , Satoshi Aida , Katsuhiko Fujimoto , Mariko Shibata , Yoshiharu Ishibashi , Mamoru Izumi , Shiroh Saitoh , Kazuya Okamoto
发明人： Takuji Suzuki , Satoshi Aida , Katsuhiko Fujimoto , Mariko Shibata , Yoshiharu Ishibashi , Mamoru Izumi , Shiroh Saitoh , Kazuya Okamoto
IPC分类号： A61B5/055 , A61B8/00 , A61B17/00 , A61B19/00 , A61N7/02 , G01R33/28 , G01R33/48
CPC分类号： G01R33/28 , A61N7/02 , G01R33/4804 , A61B2017/00694 , A61B2017/00707 , A61B2017/00716 , A61B2090/374 , A61B2090/504 , A61B5/055 , A61B6/506 , A61B8/00
摘要： An ultrasound medical treatment apparatus includes an ultrasound applicator for applying ultrasound irradiation to a treatment target. The treatment apparatus also includes an ultrasound imaging device that transmits ultrasound pulses to image the treatment target. The treatment apparatus is capable of reducing noises occurring at an ultrasound imaging device due to the ultrasound irradiation generated by the ultrasound application during ultrasound medical treatment. The noises may be reduced by increasing a transmission power of the ultrasound pulses. Alternatively, the noises may be reduced by subtracting pre-recorded noise components from the ultrasound pulses received by the ultrasound imaging device, where the pre-recorded noise components are characteristic of noise occurring at the ultrasound imaging device due to the ultrasound irradiation generated by the ultrasound applicator.
摘要翻译：超声波医疗装置包括用于对治疗对象进行超声波照射的超声波施加器。治疗装置还包括超声波成像装置，其发射超声脉冲以对治疗目标进行成像。该处理装置能够在超声波医疗中由于超声波应用产生的超声波照射而能够减少超声波摄像装置产生的噪声。可以通过增加超声脉冲的发射功率来减小噪声。或者，可以通过从由超声成像装置接收的超声波脉冲中减去预先记录的噪声分量来减少噪声，其中预先记录的噪声分量是由于由超声成像装置产生的超声波照射而在超声成像装置处发生的噪声的特征超声波施加器。

5. 发明授权

US5553618A Method and apparatus for ultrasound medical treatment 失效
标题翻译：超声医疗方法和装置
公开(公告)号：US5553618A
公开(公告)日：1996-09-10
申请号：US209528
申请日：1994-03-14
申请人： Takuji Suzuki , Satoshi Aida , Katsuhiko Fujimoto , Mariko Shibata , Yoshiharu Ishibashi , Mamoru Izumi , Shiroh Saitoh , Kazuya Okamoto
发明人： Takuji Suzuki , Satoshi Aida , Katsuhiko Fujimoto , Mariko Shibata , Yoshiharu Ishibashi , Mamoru Izumi , Shiroh Saitoh , Kazuya Okamoto
IPC分类号： A61B5/055 , A61B8/00 , A61B17/00 , A61B19/00 , A61N7/02 , G01R33/28 , G01R33/48 , A61B6/00
CPC分类号： G01R33/28 , A61N7/02 , G01R33/4804 , A61B2017/00694 , A61B2017/00707 , A61B2017/00716 , A61B2090/374 , A61B2090/504 , A61B5/055 , A61B6/506 , A61B8/00
摘要： An ultrasound medical treatment system capable of determining the hot spot at high spatial resolution, and preventing the displacement of the hot spot from the focal point. In the system, the imaging device for obtaining image data of a treatment portion containing a treatment target and an irradiation device for applying radiation onto the treatment target are controlled in such a manner that the imaging device is controlled to obtain hot spot detection image data after the irradiation device is controlled to apply radiation at a prescribed level, so that a hot spot indicating a change due to a temperature change caused by the radiation at the prescribed level can be detected from the hot spot detection image data. The irradiation device is then controlled to apply a treatment radiation at a treatment level higher than the prescribed level according to the detected hot spot.
摘要翻译：一种能够以高空间分辨率确定热点并防止热点从焦点位移的超声医疗系统。在该系统中，控制用于获得含有处理对象的处理部分的图像数据的成像装置和用于向处理对象施加辐射的照射装置，使得成像装置被控制以获得热点检测图像数据照射装置被控制为以规定的水平施加辐射，从而可以从热点检测图像数据检测到指示由于由规定水平的辐射导致的温度变化的变化的热点。然后根据检测到的热点，照射装置被控制为以高于规定水平的处理水平施加治疗放射线。

6. 发明授权

US5916161A Magnetic resonance imaging apparatus with temperature measurement function 失效
标题翻译：具有温度测量功能的磁共振成像装置
公开(公告)号：US5916161A
公开(公告)日：1999-06-29
申请号：US713430
申请日：1996-09-13
申请人： Yasutoshi Ishihara , Kazuya Okamoto
发明人： Yasutoshi Ishihara , Kazuya Okamoto
IPC分类号： G01R33/48 , A61B5/00 , A61B5/055
CPC分类号： A61B5/015 , A61B5/055
摘要： A magnetic resonance imaging apparatus capable of measuring a temperature increase due to an application of RF magnetic fields for data acquisition purpose, and notifying an information on the measured temperature increase regularly to an operator, so as to secure the safety of a body to be examined. In this magnetic resonance imaging apparatus, the image data acquisition operation is controlled to acquire a phase information associated with a temperature change in an interior of the body to be examined, by displacing either an observation start timing or a radio frequency magnetic field application timing for a prescribed magnetic resonance signal in the magnetic resonance signal sequence from a normal timing for acquiring image data.
摘要翻译：一种磁共振成像装置，其能够测量由于应用RF磁场而导致的温度升高以用于数据采集目的，并且向操作者通知关于所测量的温度升高的信息，以确保要检查的身体的安全性。在该磁共振成像装置中，控制图像数据获取操作，通过将观察开始定时或射频磁场施加定时移位，来取得与被检体内部的温度变化相关的相位信息，从用于获取图像数据的正常定时的磁共振信号序列中规定的磁共振信号。

7. 发明授权

US06194899B1 Temperature monitoring method, temperature monitoring apparatus and magnetic resonance apparatus 失效
标题翻译：温度监测方法，温度监测仪和磁共振仪
公开(公告)号：US06194899B1
公开(公告)日：2001-02-27
申请号：US09251488
申请日：1999-02-17
申请人： Yasutoshi Ishihara , Masaaki Umeda , Hidehiro Watanabe , Kazuya Okamoto
发明人： Yasutoshi Ishihara , Masaaki Umeda , Hidehiro Watanabe , Kazuya Okamoto
IPC分类号： G01V300
CPC分类号： G01R33/4804
摘要： An absolute temperature measuring pulse sequence is executed and, subsequently, a relative temperature measuring pulse sequence is repeatedly executed. Since while a relative temperature can be measured from phase information, an absolute temperature requires frequency information, a time required in the relative temperature measuring pulse can be made shorter than that required in the absolute temperature measuring pulse sequence. Since the relative temperature reveals a temperature variation, if an absolute temperature at a given time is known, an absolute temperature at a subsequent time can be calculated from the relative temperature. Thus, a local internal temperature of the subject can be measured, with a shorter temporal resolution, with the use of the absolute temperature and relative temperature.
摘要翻译：执行绝对温度测量脉冲序列，随后重复执行相对温度测量脉冲序列。由于可以从相位信息测量相对温度，所以绝对温度需要频率信息，相对温度测量脉冲所需的时间可以比绝对温度测量脉冲序列要短。由于相对温度显示温度变化，如果在给定时间内的绝对温度是已知的，则可以从相对温度计算随后时间的绝对温度。因此，可以使用绝对温度和相对温度，以较短的时间分辨率来测量受试者的局部内部温度。

8. 发明授权

US09545218B2 RF coil device and magnetic resonance imaging apparatus 有权
标题翻译： RF线圈装置和磁共振成像装置
公开(公告)号：US09545218B2
公开(公告)日：2017-01-17
申请号：US13403315
申请日：2012-02-23
申请人： Miyuki Ota , Sadanori Tomiha , Shinji Mitsui , Mitsuo Takagi , Hiroki Motohashi , Kazuya Okamoto , Junichi Makita
发明人： Miyuki Ota , Sadanori Tomiha , Shinji Mitsui , Mitsuo Takagi , Hiroki Motohashi , Kazuya Okamoto , Junichi Makita
IPC分类号： G01R33/44 , A61B5/055 , G01R33/34
CPC分类号： A61B5/0555 , G01R33/34084
摘要： In one embodiment, an RF coil device includes a base board, a belt member, a first coil element, a second coil element inside the base board, and a connecting unit. Both ends of the belt member are respectively connected to mutually separated places on the base board, so that the center part of the belt member is located on the anterior surface of the base board. The belt member is curved to form airspace between the center part thereof and the anterior surface for letting an arm pass through in interdigitation state. The first coil element includes first and second partial coils inside the belt member, and becomes a loop coil element by their connection. The connecting unit detachably connects the base board to the belt member, and mutually connects the first and second partial coils in the interdigitation state.
摘要翻译：在一个实施例中，RF线圈装置包括基板，带部件，第一线圈元件，基板内部的第二线圈元件和连接单元。带构件的两端分别连接到基板上相互分开的位置，使得带构件的中心部分位于基板的前表面上。带构件弯曲以在其中心部分和前表面之间形成空腔，以使臂在交叉状态下通过。第一线圈元件包括带部件内的第一和第二部分线圈，并且通过它们的连接成为环形线圈元件。连接单元将基板可拆卸地连接到带构件，并且以交叉状态相互连接第一和第二部分线圈。

9. 发明授权

US08643362B2 Magnetic resonance imaging apparatus having controller that sets carrier frequencies outside detected interference bands 有权
标题翻译：具有控制器的磁共振成像设备，其将载波频率设置在检测到的干扰频带
公开(公告)号：US08643362B2
公开(公告)日：2014-02-04
申请号：US13048314
申请日：2011-03-15
申请人： Takahiro Sekiguchi , Koji Akita , Toshiyuki Nakanishi , Kazuya Okamoto , Sojuro Kato
发明人： Takahiro Sekiguchi , Koji Akita , Toshiyuki Nakanishi , Kazuya Okamoto , Sojuro Kato
IPC分类号： G01R33/44
CPC分类号： G01R33/3692 , G01R33/3607
摘要： According to one embodiment, a apparatus includes a coil, a clock generator, an echo transmitter, a carrier generator, a clock transmitter, a regenerator, an receiver, a reconstructor, a detector, and a controller. The echo transmitter generates and transmits an echo transmission signal synchronously with a clock signal generated by the clock generator to wirelessly transmit an echo signal output from the col. The carrier generator generates a carrier signal have a frequency within a variable range. The clock transmitter wirelessly transmits a clock transmission signal. The regenerator regenerates the clock signal based on the transmitted clock transmission signal. The receiver extracts the echo signal synchronously with the regenerated clock signal from the transmitted echo transmission signal. The detector detects a frequency of an interference wave. The controller controls the carrier generator to generate the carrier signal having a frequency which comparatively small interference with respect to the detected frequency.
摘要翻译：根据一个实施例，一种装置包括线圈，时钟发生器，回波发射器，载波发生器，时钟发射器，再生器，接收器，重建器，检测器和控制器。回波发射机与由时钟发生器产生的时钟信号同步地生成和发送回波发送信号，以无线地发送从该列输出的回波信号。载波发生器产生具有可变范围内的频率的载波信号。时钟发射机无线传输时钟传输信号。再生器基于发送的时钟传输信号再生时钟信号。接收机从发送的回波发送信号中与再生的时钟信号同步地提取回波信号。检测器检测到干扰波的频率。控制器控制载波发生器以产生具有相对于检测到的频率具有相对小的干扰的频率的载波信号。

10. 发明授权

US08299848B2 Multi-layered semiconductor apparatus 有权
标题翻译：多层半导体装置
公开(公告)号：US08299848B2
公开(公告)日：2012-10-30
申请号：US12694008
申请日：2010-01-26
申请人： Isao Sugaya , Kazuya Okamoto
发明人： Isao Sugaya , Kazuya Okamoto
IPC分类号： H01L25/00
CPC分类号： H01L23/34 , H01L21/563 , H01L23/3128 , H01L23/36 , H01L23/473 , H01L25/0657 , H01L2224/0554 , H01L2224/05573 , H01L2224/05611 , H01L2224/05639 , H01L2224/05644 , H01L2224/05647 , H01L2224/05655 , H01L2224/13025 , H01L2224/16145 , H01L2224/16225 , H01L2225/06541 , H01L2225/06589 , H01L2924/00014 , H01L2924/15311 , H01L2924/15321 , H01L2224/05599 , H01L2224/0555 , H01L2224/0556
摘要： Provided is a multi-layered semiconductor apparatus with improved heat diffusion and improved heat release. The multi-layered semiconductor apparatus (100) includes a plurality of layered semiconductor chips (20-1, 20-2) that each include at least one circuit region, and the circuit regions are arranged such that heat generated by the circuit regions as a result of the circuit regions being driven is spread out. The multi-layered semiconductor apparatus (100) further comprises a heat releasing section (50) that releases the heat generated by the circuit regions, and the circuit regions are arranged such that there is less thermal resistance between the heat releasing section and circuit regions that generate a greater amount of heat per unit area.
摘要翻译：提供了一种具有改进的热扩散和改进的放热的多层半导体装置。多层半导体装置（100）包括多个分层半导体芯片（20-1,20-2），每个半导体芯片包括至少一个电路区域，并且电路区域被布置成使得由电路区域产生的热量作为驱动电路区域的结果展开。所述多层半导体装置（100）还包括释放由所述电路区域产生的热的放热部（50），所述电路区域配置成使得所述散热部与所述电路区之间的热阻较小，每单位面积产生更大的热量。

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