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1. 发明授权

US08574201B2 Syringe piston with check valve seal 有权
公开(公告)号：US08574201B2
公开(公告)日：2013-11-05
申请号：US12972263
申请日：2010-12-17
申请人： Sarnath Chattaraj , Poonam S. Gulati , Lance P. Hoffman , Kiem Dang
发明人： Sarnath Chattaraj , Poonam S. Gulati , Lance P. Hoffman , Kiem Dang
IPC分类号： A61M5/315
CPC分类号： A61M5/36 , A61M5/31511 , A61M5/31513 , Y10T29/49826
摘要： A fluid syringe of the type used with fluid infusion devices is presented here. The fluid syringe generally includes a barrel, a piston, and a check valve seal. The barrel has an interior wall and a sealed main fluid chamber. The piston is slidably coupled within the barrel, and the piston has a piston seal forming an interference fluid seal against the interior wall. The check valve seal is coupled to the piston, and it is located between the piston seal and the main fluid chamber. The check valve seal forms an interference fluid seal against the interior wall when the piston is unloaded, and it disengages the interior wall to allow gas flow from the main fluid chamber toward the piston seal when the piston is loaded.

2. 发明授权

US09265890B2 Syringe piston with finned sealing cover 有权
标题翻译：注射器活塞带翅片密封盖
公开(公告)号：US09265890B2
公开(公告)日：2016-02-23
申请号：US13415740
申请日：2012-03-08
申请人： Sarnath Chattaraj , Poonam S. Gulati , Kiem Dang , Jocelyn Anne Montebon
发明人： Sarnath Chattaraj , Poonam S. Gulati , Kiem Dang , Jocelyn Anne Montebon
IPC分类号： A61M5/315
CPC分类号： A61M5/31511 , A61M5/31513
摘要： Syringe pistons for a fluid syringe, and related sealing elements, are presented here. A syringe piston includes a piston body having a fluid end, an actuator end, and an outer seal-retaining surface between the fluid end and the actuator end. The syringe piston may utilize a piston sealing sleeve or a piston sealing cover. The sleeve can be coupled to the piston body around the outer seal-retaining surface, the piston sealing sleeve having a fin-shaped fluid seal element to form an interference fluid seal with an interior wall of a syringe barrel. The sealing cover can be coupled overlying the tip of the piston body. The cover has a fin-shaped fluid seal element to form an interference fluid seal with an interior wall of a syringe barrel.
摘要翻译：用于流体注射器的注射器活塞以及相关的密封元件。注射器活塞包括具有流体端的活塞体，致动器端和在流体端和致动器端之间的外部密封保持面。注射器活塞可以利用活塞密封套筒或活塞密封盖。套筒可以围绕外密封件保持表面联接到活塞体，活塞密封套管具有翅片形流体密封元件，以与注射器筒的内壁形成干涉流体密封。密封盖可以联接在活塞体的尖端上。盖具有翅片状流体密封元件，以与注射器筒的内壁形成干涉流体密封。

3. 发明申请

US20110152820A1 BARRIER COATINGS FOR FLUIDS CONTACTING MEDICAL DEVICES 审中-公开
标题翻译：用于流体接触医疗器械的障碍涂层
公开(公告)号：US20110152820A1
公开(公告)日：2011-06-23
申请号：US12974914
申请日：2010-12-21
申请人： Sarnath Chattaraj , Kiem Dang , Poonam S. Gulati
发明人： Sarnath Chattaraj , Kiem Dang , Poonam S. Gulati
IPC分类号： A61L31/14 , B65D81/24 , A61J1/14 , B05D3/06 , B65B1/04
CPC分类号： A61M5/14546
摘要： The invention relates to methods and materials that, for example, function to increase the barrier properties of containers including polymeric drug medication reservoirs and related containers such as infusion set tubing. Embodiments of the invention include aqueous container systems having containers coated with a composition selected to have one or more material properties including an ability to reduce the diffusion or permeation of compounds such as oxygen, carbon dioxide, and preservatives (e.g. phenol, benzyl alcohol and m-cresol) into or through a wall of the container.
摘要翻译：本发明涉及例如用于增加包括聚合物药物药物储存器在内的容器和相关容器（例如输液管）的阻隔性能的方法和材料。本发明的实施方案包括水性容器系统，其具有涂覆有组合物的容器，所述组合物被选择为具有一种或多种材料性质，包括减少化合物如氧气，二氧化碳和防腐剂（例如苯酚，苄醇和m）的扩散或渗透的能力甲酚）插入或穿过容器的壁。

4. 发明申请

US20060041296A1 Novel medical electrode configurations 审中-公开
标题翻译：新型医用电极配置
公开(公告)号：US20060041296A1
公开(公告)日：2006-02-23
申请号：US10924024
申请日：2004-08-23
申请人： Ryan Bauer , Kiem Dang , John Sommer
发明人： Ryan Bauer , Kiem Dang , John Sommer
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0565 , A61N1/057 , A61N2001/0585
摘要： A medical electrode includes an active surface extending from a first end to a second end and has a maximum outer diameter exceeding an outer diameter of the both the first end and the second end. The electrode further includes a recess formed in the active surface and an agent held in the recess and adapted to disperse out from the recess upon implantation of the electrode.
摘要翻译：医疗电极包括从第一端延伸到第二端的有效表面，并且具有超过第一端和第二端的外径的最大外径。所述电极还包括形成在所述活性表面中的凹部和保持在所述凹部中并适于在注入所述电极时从所述凹部分散出的试剂。

5. 发明申请

US20060041297A1 Novel electrode assembly for medical electrical leads 审中-公开
标题翻译：用于医疗电线的新型电极组件
公开(公告)号：US20060041297A1
公开(公告)日：2006-02-23
申请号：US10924054
申请日：2004-08-23
申请人： Ryan Bauer , Kiem Dang , John Sommer
发明人： Ryan Bauer , Kiem Dang , John Sommer
IPC分类号： A61N1/05
CPC分类号： A61N1/0568 , A61N2001/0585
摘要： A lumen seal of a medical electrical lead includes an outer surface adapted to form a portion of an exterior surface of the medical electrical lead and an inner surface adapted to seal off a lumen of the lead and yet allow passage of an elongate member that is slidably engaged within the lumen of the lead. The seal further includes a portion in which an agent is embedded, the agent adapted to disperse from the portion out through the outer surface of the seal.
摘要翻译：医疗电引线的管腔密封件包括适于形成医用电线的外表面的一部分的外表面和适于密封引线内腔的内表面，并允许可滑动地延伸的细长构件通过从事导管内腔。密封件还包括其中嵌入有试剂的部分，所述试剂适于从部分通过密封件的外表面分散出来。

6. 发明申请

US20050064038A1 Active agent delivery systems including a single layer of a miscible polymer blend, medical devices, and methods 审中-公开
标题翻译：活性剂递送系统，包括单层可混溶聚合物共混物，医疗装置和方法
公开(公告)号：US20050064038A1
公开(公告)日：2005-03-24
申请号：US10916159
申请日：2004-08-11
申请人： Thomas Dinh , Randall Sparer , SuPing Lyu , Kiem Dang , Christopher Hobot
发明人： Thomas Dinh , Randall Sparer , SuPing Lyu , Kiem Dang , Christopher Hobot
IPC分类号： A61K9/00 , A61K47/34 , A61L27/34 , A61L27/54 , A61L31/10 , A61L31/16 , A61K9/14
CPC分类号： A61K9/0024 , A61K47/34 , A61L27/34 , A61L27/54 , A61L31/10 , A61L31/16 , A61L2300/45 , A61L2300/602
摘要： An active agent delivery system that includes two or more active agents in a layer of a miscible polymer blend having at least two miscible polymers; wherein delivery of at least one of the active agents occurs predominantly under permeation control; and further wherein the permeability of the active agent that is to be released faster is greater than the permeability of the other one or more active agents.
摘要翻译：一种活性剂递送系统，其包含在具有至少两种可混溶聚合物的可混溶聚合物共混物层中的两种或更多种活性剂; 其中至少一种活性剂的递送主要在渗透控制下发生; 并且其中待释放的活性剂的渗透性比其它一种或多种活性剂的渗透性大。

7. 发明申请

US20050064005A1 Active agent delivery systems including a miscible polymer blend, medical devices, and methods 审中-公开
标题翻译：包括可混溶聚合物共混物，医疗装置和方法的活性剂递送系统
公开(公告)号：US20050064005A1
公开(公告)日：2005-03-24
申请号：US10916162
申请日：2004-08-11
申请人： Thomas Dinh , Randall Sparer , SuPing Lyu , Kiem Dang , Christopher Hobot
发明人： Thomas Dinh , Randall Sparer , SuPing Lyu , Kiem Dang , Christopher Hobot
IPC分类号： A61F2/00 , A61F2/82 , A61K9/00 , A61L27/34 , A61L27/54 , A61L29/08 , A61L29/16 , A61L31/04 , A61L31/10 , A61L31/16 , A61K9/14
CPC分类号： A61L31/16 , A61F2/07 , A61F2/82 , A61F2250/0067 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/16 , A61L31/10 , A61L2300/41 , A61L2300/416 , A61L2300/45 , A61L2300/602 , A61L2300/61
摘要： An active agent delivery system that includes two or more active agents and two or more layers of polymers; wherein at least one layer includes miscible polymer blend comprising two or more miscible polymers; and further wherein delivery of at least one active agent occurs predominantly under permeation control.
摘要翻译：包含两种或更多种活性剂和两层或多层聚合物的活性剂递送系统; 其中至少一层包括包含两种或更多种可混溶聚合物的混溶性聚合物共混物; 并且其中至少一种活性剂的递送主要在渗透控制下进行。

8. 发明授权

US07065394B2 Guide catheter 失效
公开(公告)号：US07065394B2
公开(公告)日：2006-06-20
申请号：US10016114
申请日：2001-12-12
申请人： Christopher M. Hobot , Stanten C. Spear , James F. Kelley , Jennifer L. Braunschweig , Kiem Dang , Kenneth C. Gardeski
发明人： Christopher M. Hobot , Stanten C. Spear , James F. Kelley , Jennifer L. Braunschweig , Kiem Dang , Kenneth C. Gardeski
IPC分类号： A61B5/05
CPC分类号： A61M25/0108 , A61L29/02 , A61L29/18 , A61M25/005
摘要： A guide catheter has properties that promote enhanced visibility of the guide catheter using fluoroscopic or ultrasonic imaging techniques. The tip of the guide catheter may incorporate a material that is both fluoro and echo visible. The first material also may be provided in various amounts along the length of the guide catheter. In addition, the guide catheter may incorporate a reinforcing braid that includes one or more strands of a second material that is radio-opaque. As a result, the result guide catheter achieves improved radio-opacity and echogenicity.

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