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    • 2. 发明申请
    • Method for Whole Surrounding Surface Display of Target Proteins Using Bacterial Exoporium
    • 使用细菌外植体的靶蛋白整体表面显示方法
    • US20070269838A1
    • 2007-11-22
    • US10572224
    • 2003-12-30
    • Sang LeeTae ParkJong ParkSeok LeeJae-Gu PanHeung-Chae JungSoo-Keun Choi
    • Sang LeeTae ParkJong ParkSeok LeeJae-Gu PanHeung-Chae JungSoo-Keun Choi
    • C12P21/06C12N1/21C07K14/195C07K14/52
    • C40B40/02C12N15/1037
    • The present invention relates to a method for expressing a target protein on an exosporium forming the outermost surface of bacterial spores. More particularly, the present invention relates to a method for expressing a target protein on the surface of cells and spores using an exosporium as a matrix for surface expression, and methods for the production of a protein array, the production of antibodies, the separation of a certain substance from a mixture, bioconversion, and the improvement of a target protein, which are characterized by using the cells or spores having the target protein that was expressed on the surface by the above expression method. The method for expressing the target protein on the surface of the spore outer membrane of the gene carriers according to the present invention has effects in that a variety of the target proteins can be expressed and the level of surface expression of the target protein is increased compared to the existing technology, and also the structural stability of the gene carriers having the target protein expressed on their surface, the viability of the host, and the rapidity of the screening method, are greatly increased.
    • 本发明涉及在形成细菌孢子的最外表面的外孢上表达靶蛋白的方法。 更具体地说,本发明涉及使用外鎓作为表面表达基质在细胞和孢子表面上表达靶蛋白的方法,以及用于产生蛋白质阵列,产生抗体的方法,分离 特定于使用具有通过上述表达方法在表面表达的靶蛋白的细胞或孢子的来自混合物的某种物质,生物转化和靶蛋白的改良。 根据本发明的用于在基因载体的孢子外膜的表面上表达靶蛋白的方法具有以下效果:可以表达多种靶蛋白,并且与目标蛋白的表面表达水平相比提高了靶蛋白的表达表达水平 现有技术,以及表面上具有靶蛋白的基因载体的结构稳定性,宿主的活力以及筛选方法的快速性都大大提高。
    • 3. 发明申请
    • Electron emission device and electron emission display using the same
    • 电子发射器件和使用其的电子发射显示器
    • US20060006788A1
    • 2006-01-12
    • US11138218
    • 2005-05-25
    • Sang LeeJong Choi
    • Sang LeeJong Choi
    • H01J1/62H01J63/04
    • H01J1/30
    • An electron emission device and an electron emission display, in which a driving electrode is protected from being damaged when an overcurrent instantly flows therein. The electron emission device includes a first driving electrode disposed on a plate, a second driving electrode disposed on the plate and insulated from the first driving electrode, and an electron emission portion connected to the first driving electrode. The electron emission portion emits electrons in response to a voltage difference between the first driving electrode and the second driving electrode. The second driving electrode has at least two separate portions, and the at least two separate portions are coupled to each other by at least one band having a predetermined width adapted to electrically isolate at least one portion of the second driving electrode from the electron emission portion when an overcurrent is applied between the second driving electrode and the electron emission portion.
    • 电子发射装置和电子发射显示器,其中当过电流瞬时流过其中时,保护驱动电极不被损坏。 电子发射装置包括设置在板上的第一驱动电极,设置在板上并与第一驱动电极绝缘的第二驱动电极和连接到第一驱动电极的电子发射部分。 电子发射部分响应于第一驱动电极和第二驱动电极之间的电压差发射电子。 所述第二驱动电极具有至少两个分开的部分,并且所述至少两个分离部分通过具有预定宽度的至少一个带彼此耦合,所述至少一个带适于将所述第二驱动电极的至少一部分与所述电子发射部分 当在第二驱动电极和电子发射部分之间施加过电流时。
    • 4. 发明申请
    • Method for fabricating a biochip using the high density carbon nanotube film or pattern
    • 使用高密度碳纳米管膜或图案制造生物芯片的方法
    • US20050019791A1
    • 2005-01-27
    • US10805044
    • 2004-03-19
    • Hee JungSang LeeDae JungByung KimYoung Ko
    • Hee JungSang LeeDae JungByung KimYoung Ko
    • B82B3/00B05D3/00B82B1/00C12M1/00C12M1/34C12N15/09C12Q1/68G01N33/543G01N33/551
    • G01N33/54353B82Y30/00G01N33/551Y10S977/742
    • The present invention relates to a CNT-biochip comprising a bio-receptor which is attached by means of an exposed chemical functional group on a surface of a high density CNT film or pattern which is produced by laminating repeatedly carbon nanotubes (CNT) by chemical bond on the substrate modified with amine groups, and a method for fabricating the same. According to the present invention, it is possible to fabricate various types of CNT-biochips by chemical or physicochemical bonding of various bio-receptors to a CNT pattern (or film) containing exposed carboxyl groups or a CNT pattern (or film) modified by various chemical functional groups. Also, it is possible to fabricate a CNT-biochip comprising bio-receptors attached evenly with high density on a surface of a CNT film where chemical functional groups are abundant and present evenly. Further, the CNT-biochip is applicable to next generation biochips which measure an electrical or electrochemical signal using both conductor and semiconductor properties of the CNT, thereby not needing labeling. Particularly, upon fluorescent measurement of DNA hybridization using the CNT-DNA chip according to the present invention, it is possible to show more distinct signals, thereby producing excellent results. The CNT-DNA chip is useful for genotyping, mutation detection, pathogen identification and the like.
    • 本发明涉及一种CNT生物芯片,其包含通过暴露的化学官能团在高密度CNT膜或图案的表面上附着的生物受体,其通过化学键层叠多次碳纳米管(CNT)制备 在用胺基改性的基材上,以及其制造方法。 根据本发明,可以通过各种生物受体与包含暴露的羧基的CNT图案(或膜)的化学或物理化学键合或通过各种改变的CNT图案(或膜)来制造各种类型的CNT-生物芯片 化学官能团。 此外,可以制造CNT-生物芯片,其包含在CNT膜的表面上高度均匀地附着的生物受体,其中化学官能团丰富并均匀存在。 此外,CNT-生物芯片适用于使用CNT的导体和半导体性质测量电或电化学信号的下一代生物芯片,因此不需要标记。 特别是在使用本发明的CNT-DNA芯片进行DNA杂交的荧光测定时,可以显示更多不同的信号,从而产生优异的结果。 CNT-DNA芯片可用于基因分型,突变检测,病原体鉴定等。
    • 10. 发明申请
    • Camera module having an array lens
    • 相机模块具有阵列透镜
    • US20080007623A1
    • 2008-01-10
    • US11822301
    • 2007-07-03
    • Sang LeeHo JeongSeok LeeHo YouSung Kim
    • Sang LeeHo JeongSeok LeeHo YouSung Kim
    • H04N5/225H04N9/04
    • H04N9/04G02B13/001G02B13/006G02B13/0085G02B13/009H01L27/14618H01L2924/0002H04N5/2253H04N5/2254H04N5/2257H01L2924/00
    • In a camera module having an array lens, a first lens group has at least two lenses. A second lens group has a plurality of lenses corresponding to the lenses of the first lens group, the second lens group stacked below the first lens group and interposing a spacer part therebetween. An image sensor has an imaging region where light passing through the first and second lens groups is imaged. Also, a shielding unit shields portions excluding apertures of the lenses of the first and second lens groups, the shielding unit disposed between the first and second lens groups. The camera module has a lower optical system along an optical axis for smaller size, keeps light refracted from an adjacent lens from affecting an image, blocks leakage of light for imaging and increases definition of the image through signal processing.
    • 在具有阵列透镜的相机模块中,第一透镜组具有至少两个透镜。 第二透镜组具有对应于第一透镜组的透镜的多个透镜,第二透镜组堆叠在第一透镜组下方并且在其间插入间隔部分。 图像传感器具有通过第一和第二透镜组的光成像的成像区域。 此外,屏蔽单元屏蔽除了第一和第二透镜组的透镜的孔的部分,屏蔽单元设置在第一和第二透镜组之间。 相机模块沿着光轴具有较小的光学系统,以便较小的尺寸,保持相邻透镜的光线不会影响图像,阻止用于成像的光的泄漏,并通过信号处理增加图像的定义。