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1. 发明授权

US06887852B1 Pharmaceutical preparation of recombinant factor VIII lyophilized without albumin as a stabilizer 有权
标题翻译：重组因子VIII的药物制剂冻干，无白蛋白作为稳定剂
公开(公告)号：US06887852B1
公开(公告)日：2005-05-03
申请号：US10912167
申请日：2004-08-06
申请人： Sang Hoon Paik , Yong Nam Shin , Jean Man Kim , Jae Wook Huh , Jung Sik Lee , Ki Sung Kwon , Ji Hyun Chun
发明人： Sang Hoon Paik , Yong Nam Shin , Jean Man Kim , Jae Wook Huh , Jung Sik Lee , Ki Sung Kwon , Ji Hyun Chun
IPC分类号： A61K38/16 , A61K9/19 , A61K38/37 , A61K47/18 , C07K14/755 , A61K38/00 , A61K35/14 , C12P21/02
CPC分类号： A61K9/19 , A61K38/37 , A61K47/183 , C07K14/755
摘要： Disclosed is a lyophilized preparation of recombinant factor VIII used as a therapeutic preparation of hemophilia A. The lyophilized preparation of recombinant factor VIII is prepared by performing lyophilization using a mixture comprising 6 to 100 mM of L-arginine, 3.5 to 50 mM of L-isoleucine, and 10 to 100 mM of L-glutamic acid as a stabilizer for stabilizing the recombinant factor VIII which exhibits an unstable activity during lyophilization, rather than using human blood derived albumin.
摘要翻译：公开了用作血友病A的治疗制剂的重组因子VIII的冻干制剂。重组因子VIII的冻干制剂通过使用包含6至100mM L-精氨酸，3.5至50mM L- 异亮氨酸和10至100mM的L-谷氨酸作为稳定重组因子VIII的稳定剂，其在冻干期间表现出不稳定的活性，而不是使用人血清白蛋白。

2. 发明授权

US09295655B2 Fentanyl transdermal patch 有权
标题翻译：芬太尼透皮贴剂
公开(公告)号：US09295655B2
公开(公告)日：2016-03-29
申请号：US14004889
申请日：2012-03-13
申请人： Young Kwen Choi , Jung Ju Kim , Jung Sik Lee , Sung Soo Kim
发明人： Young Kwen Choi , Jung Ju Kim , Jung Sik Lee , Sung Soo Kim
IPC分类号： A61K9/70 , A61K31/4468 , A61M35/00 , A61F13/02 , A61L15/44 , A61L15/58 , A61K31/454
CPC分类号： A61K9/7076 , A61F13/02 , A61F13/0206 , A61F13/0246 , A61F13/0253 , A61F13/0256 , A61K9/7053 , A61K31/4468 , A61K31/454 , A61L15/44 , A61L15/58 , A61L2300/402 , A61M35/00 , F04C2270/0421 , C08L33/08
摘要： Provided is a fentanyl transdermal patch comprising an acrylic-rubber hybrid as a drug-adhesive layer. The fentanyl transdermal patch can maintain constant fentanyl skin permeability for three days by maintaining close contact with the skin such that desorption, release by moisture and sweat, and skin stimulation are all improved.
摘要翻译：本发明提供一种芬太尼透皮贴剂，其包含作为药物 - 粘合剂层的丙烯酸 - 橡胶杂化物。通过与皮肤保持紧密接触，芬太尼透皮贴剂可以保持芬太尼皮肤的不断渗透，持续三天，从而改善了解吸，水分和汗水释放以及皮肤刺激。

3. 发明申请

US20140005617A1 FENTANYL TRANSDERMAL PATCH 有权
公开(公告)号：US20140005617A1
公开(公告)日：2014-01-02
申请号：US14004889
申请日：2012-03-13
申请人： Young Kwen Choi , Jung Ju Kim , Jung Sik Lee , Sung Soo Kim
发明人： Young Kwen Choi , Jung Ju Kim , Jung Sik Lee , Sung Soo Kim
IPC分类号： A61K9/70 , A61K31/4468 , A61M35/00
CPC分类号： A61K9/7076 , A61F13/02 , A61F13/0206 , A61F13/0246 , A61F13/0253 , A61F13/0256 , A61K9/7053 , A61K31/4468 , A61K31/454 , A61L15/44 , A61L15/58 , A61L2300/402 , A61M35/00 , F04C2270/0421 , C08L33/08
摘要： Provided is a fentanyl transdermal patch comprising an acrylic-rubber hybrid as a drug-adhesive layer. The fentanyl transdermal patch can maintain constant fentanyl skin permeability for three days by maintaining close contact with the skin such that desorption, release by moisture and sweat, and skin stimulation are all improved.
摘要翻译：本发明提供一种芬太尼透皮贴剂，其包含作为药物 - 粘合剂层的丙烯酸 - 橡胶杂化物。通过与皮肤保持紧密接触，芬太尼透皮贴剂可以保持芬太尼皮肤的不断渗透，持续三天，从而改善了解吸，水分和汗水释放以及皮肤刺激。

4. 发明授权

US09338337B2 Camera module having a dust trap 有权
标题翻译：相机模块有一个除尘器
公开(公告)号：US09338337B2
公开(公告)日：2016-05-10
申请号：US14348774
申请日：2012-09-28
申请人： Jung Sik Lee
发明人： Jung Sik Lee
IPC分类号： H04N5/225 , H04N3/14 , G03B17/08
CPC分类号： H04N5/2252 , G03B17/08 , H04N5/2253 , H04N5/2254 , H04N5/2257
摘要： The present invention relates to a camera module, the camera module including a base supporting a filter member mounted on a position corresponding to that of an image sensor mounted on a PCB (Printed Circuit Board), a dust trap unit mounted about the filter member of the base to collect soils including dust introduced into the filter member, wherein the dust trap unit includes an epoxy reception groove formed with one or more ribs formed at a periphery of the filter member mounted at the base, and a dust trap epoxy coated on an inside of the epoxy receptin groove.
摘要翻译：相机模块本发明涉及一种相机模块，该相机模块包括支撑安装在安装在PCB（印刷电路板）上的图像传感器的位置的位置上的过滤器部件的基座;安装在过滤器部件用于收集包括引入过滤构件的灰尘的污物的基底，其中所述除尘单元包括形成有安装在所述基部的所述过滤构件的周边处形成有一个或多个肋的环氧树脂接收槽和涂覆在所述过滤构件上的防尘圈环氧树脂在环氧树脂接收槽内。

5. 发明授权

US08986756B2 Composition comprising the extract of combined herbs for preventing and treating liver disease 有权
标题翻译：包含用于预防和治疗肝脏疾病的组合草药提取物的组合物
公开(公告)号：US08986756B2
公开(公告)日：2015-03-24
申请号：US12520534
申请日：2007-12-18
申请人： Jung Sik Lee
发明人： Jung Sik Lee
IPC分类号： A61K36/79 , A61K36/282 , A61K36/06 , A61K36/481 , A61K36/07 , A23L1/30
CPC分类号： A61K36/07 , A23L33/105 , A23V2002/00 , A61K36/282 , A61K36/481 , A61K36/79 , A61K2300/00 , A23V2200/30 , A23V2250/21 , A23V2200/32
摘要： The present invention is related to a combined herb composition comprising herbs of Coriolus versicolor, Astragalus membranaceus Bunge, and additionally comprising at least one herb selected from group consisting of Schisandra chinensis, and Artemisia capillaris, according to the need for the prevention and treatment of liver disease and methods of using the above crude drug composition and pharmaceutical composition as hepato-protective agent.
摘要翻译：本发明涉及一种组合的草本植物组合物，其包含芫荽子草黄芪，另外包含至少一种选自中国五味子和青蒿的草药，根据对肝脏的预防和治疗的需要使用上述生药组合物和药物组合物作为肝保护剂的疾病和方法。

6. 发明申请

US20130165875A1 TRANSDERMAL ABSORPTION PREPARATION 审中-公开
标题翻译：超吸收制剂
公开(公告)号：US20130165875A1
公开(公告)日：2013-06-27
申请号：US13642960
申请日：2011-04-21
申请人： Young Kweon Choi , Jung Ju Kim , Seong Su Kim , Jung Sik Lee , Seong Min Park
发明人： Young Kweon Choi , Jung Ju Kim , Seong Su Kim , Jung Sik Lee , Seong Min Park
IPC分类号： A61M35/00
CPC分类号： A61K9/7061 , A61K9/7053 , A61K9/7076 , A61K31/4045
摘要： The present, invention relates to a transdermal absorption preparation. The transdermal absorption preparation of the present invention comprises a drug-containing adhesive layer, a drug-protective layer and a release layer, wherein the drug-containing adhesive layer contains ropinirole or a salt thereof, rubber, an adhesion-imparting resin, an antioxidant, and a transdermal absorption promoter. Also, the present invention provides a transdermal absorption preparation comprising a drug-containing adhesive layer, a drug-protective layer, and a release layer, wherein the drug-containing adhesive layer contains ropinirole or a salt thereof, acrylic rubber, an anti-crystallisation agent, and a transdermal absorption promoter. When the transdermal absorption preparation of the present invention is used for the treatment of Parkinson's disease or restless leg syndrome, no side effect due to an increase in the initial drug concentration in blood occurs and the skin penetration effect of the drug is excellent.
摘要翻译：本发明涉及一种透皮吸收制剂。本发明的透皮吸收制剂包含含药物的粘合剂层，药物保护层和剥离层，其中含药物的粘合剂层含有罗哌尼罗或其盐，橡胶，赋形树脂，抗氧化剂，和透皮吸收促进剂。另外，本发明提供了含有药物的粘合剂层，药物保护层和剥离层的透皮吸收制剂，其中含药物的粘合剂层含有罗哌尼罗或其盐，丙烯酸橡胶，抗结晶试剂和透皮吸收促进剂。当本发明的经皮吸收制剂用于治疗帕金森病或不宁腿综合征时，由于血液中初始药物浓度的增加而引起副作用，药物的皮肤渗透作用优异。

7. 发明申请

US20100092584A1 Composition Comprising the Extract of Combined Herbs for Preventing and Treating Liver Disease 有权
标题翻译：组合物包含用于预防和治疗肝病的组合草药提取物
公开(公告)号：US20100092584A1
公开(公告)日：2010-04-15
申请号：US12520534
申请日：2007-12-18
申请人： Jung Sik Lee
发明人： Jung Sik Lee
IPC分类号： A61K36/282 , A61K36/00
CPC分类号： A61K36/07 , A23L33/105 , A23V2002/00 , A61K36/282 , A61K36/481 , A61K36/79 , A61K2300/00 , A23V2200/30 , A23V2250/21 , A23V2200/32
摘要： The present invention is related to a combined herb composition comprising herbs of Coriolus versicolor, Astragalus membranaceus Bunge, and additionally comprising at least one herb selected from group consisting of Schisandra chinensis, and Artemisia capillaris, according to the need for the prevention and treatment of liver disease and methods of using the above crude drug composition and pharmaceutical composition as hepato-protective agent.
摘要翻译：本发明涉及一种组合的草本植物组合物，其包含芫荽子草黄芪，另外包含至少一种选自中国五味子和青蒿的草药，根据对肝脏的预防和治疗的需要使用上述生药组合物和药物组合物作为肝保护剂的疾病和方法。

8. 发明授权

US6074648A Galenic preparation for prevention and treatment of hepatocarcinoma 失效
标题翻译： Galenic预防和治疗肝癌的准备
公开(公告)号：US6074648A
公开(公告)日：2000-06-13
申请号：US130488
申请日：1998-08-07
申请人： Jung Sik Lee
发明人： Jung Sik Lee
IPC分类号： A61K36/00 , A47C1/035 , A61K20060101 , A61K36/068 , A61K36/233 , A61K36/28 , A61K36/282 , A61K36/31 , A61K36/48 , A61K36/539 , A61K36/708 , A61K36/748 , A61K36/884 , A61K36/896 , A61P20060101 , A61P1/16 , A61P35/00 , G11B27/00 , A61K35/78
CPC分类号： A61K36/884 , A61K36/068 , A61K36/233 , A61K36/28 , A61K36/282 , A61K36/31 , A61K36/48 , A61K36/539 , A61K36/708 , A61K36/896
摘要： The present invention relates to a galenic preparation for prevention and treatment of hepatocarcinoma. More specifically, the present invention relates to a galenic preparation which comprises an injectable composition having a good preventive and therapeutic effect particularly against hepatitis B virus and containing 4 kinds of main natural drugs, i.e., Hedyotidis herba, Curcumae longae rhizoma, Polygonati cuspidati radix and Sophorae tonkinesis radix; and an oral composition having a preventive and therapeutic effect against fatty liver and hepatic cirrhosis and containing 10 kinds of natural drugs, i.e., Hedyotidis herba, Paridis rhizoma, Polygoni cuspidati radix, Sophorae tonkinesis radix, Gentianae scabrae radix, Rhei rhizoma, Forsythiae fructus, Paeoniae radix rubra, Curcumae longae rhizoma and Acori graminei rhizoma, and which can effectively prevent the development of hepatic diseases including hepatitis, fatty liver and hepatic cirrhosis into hepatocarcinoma and treat hepatocarcinoma by combined administration of two kinds of the compositions.
摘要翻译：本发明涉及一种预防和治疗肝癌的盖仑制剂。更具体地说，本发明涉及一种包衣制剂，其包含具有良好的预防和治疗效果，特别是针对乙型肝炎病毒的可注射组合物，并含有4种主要天然药物，即Hedyotidis herba，Curcumae longae rhizoma，Polygonati cuspidati radix和苦参碱并具有对脂肪肝和肝硬化的预防和治疗作用的口服组合物，并且含有10种天然药物，即Hedyotidis herba，Paridis rhizoma，Polygoni cuspidati radix，Sophorae tonkinesis radix，Gentianae scabrae radix，Rhei rhizoma，Forsythiae fructus，芍药，莪术和禾本科，可有效预防肝炎，脂肪肝，肝硬化等肝病发展为肝癌，并通过联合给药两种组合物治疗肝癌。

9. 发明申请

US20140247389A1 Camera Module 有权
标题翻译：相机模块
公开(公告)号：US20140247389A1
公开(公告)日：2014-09-04
申请号：US14348774
申请日：2012-09-28
申请人： Jung Sik Lee
发明人： Jung Sik Lee
IPC分类号： H04N5/225
CPC分类号： H04N5/2252 , G03B17/08 , H04N5/2253 , H04N5/2254 , H04N5/2257
摘要： The present invention relates to a camera module, the camera module including a base supporting a filter member mounted on a position corresponding to that of an image sensor mounted on a PCB (Printed Circuit Board), a dust trap unit mounted about the filter member of the base to collect soils including dust introduced into the filter member, wherein the dust trap unit includes an epoxy reception groove formed with one or more ribs formed at a periphery of the filter member mounted at the base, and a dust trap epoxy coated on an inside of the epoxy receptin groove.
摘要翻译：相机模块本发明涉及一种相机模块，该相机模块包括支撑安装在安装在PCB（印刷电路板）上的图像传感器的位置的位置上的过滤器部件的基座;安装在过滤器部件用于收集包括引入过滤构件的灰尘的污物的基底，其中所述除尘单元包括形成有安装在所述基部的所述过滤构件的周边处形成有一个或多个肋的环氧树脂接收槽和涂覆在所述过滤构件上的防尘圈环氧树脂在环氧树脂接收槽内。

10. 发明授权

US5916555A Pharmaceutical composition for treatment of diabetes 失效
标题翻译：用于治疗糖尿病的药物组合物
公开(公告)号：US5916555A
公开(公告)日：1999-06-29
申请号：US961069
申请日：1997-10-30
申请人： Jung Sik Lee , Chung San Kong , Song Deuk Lee , Kyung Eun Kwak
发明人： Jung Sik Lee , Chung San Kong , Song Deuk Lee , Kyung Eun Kwak
IPC分类号： A61K36/00 , A61K20060101 , A61K35/37 , A61K35/38 , A61K35/56 , A61K35/62 , A61K36/066 , A61K36/07 , A61K36/48 , A61P20060101 , A61P3/10 , A61P7/02 , A61K35/70 , A61K35/78
CPC分类号： A61K36/00 , A61K36/07
摘要： The present invention relates to a pharmaceutical composition containing a combination of natural drugs for treatment of diabetes. More specifically, the present invention relates to a composition containing 17 kinds of main natural drugs, i. e. Cordyceps, Bezoar bovis, Carthami flos, Astragali radix, Hirudo, Polygoni cuspidati radix, Polygonati falcati rhizoma, Euonymi lignum suberalatum, Corni fructus, Moutan cortex, Lycii cortex radicis, Lycii fructus, Atractylodis rhizoma alba, Atractylodis rhizoma, Coptidis rhizoma, Puerariae radix and Rehmaniae radix crudae. In addition to 17 kinds of main natural drugs, if desired, the composition of the present invention can contain one or more supplementary natural drugs selected from the group consisting of Liriopsis tuber, Cistanchis herba, Adenophorae radix, Salviae radix, Ginseng radix rubra, Anemarrhenae rhizoma, Pachymae fungus, Phellodendri cortex, Mori radicis cortex, Schizandrae fructus, Galli stomachichum corium, Trichosanthis radix, Rhei rhizoma, Dioscoreae rhizoma, Alisma rhizoma, Polygoni multiflori radix, Galla rhois, Formica fusca L., Sanchi ginseng, Margaritum and Gecko. The composition of the present invention is an agent for prevention of diabetes and for prevention and treatment of complications concomitant with diabetes by decreasing the blood sugar level of diabetic patients, but not decreasing the blood sugar level of normal person, and decreasing the blood lipid level, and therefore, is particularly effective for treatment of noninsulin-dependent diabetes (Type II diabetes) as well as insulin-dependent diabetes (Type I diabetes).
摘要翻译：本发明涉及含有用于治疗糖尿病的天然药物的组合的药物组合物。更具体地说，本发明涉及含有17种主要天然药物的组合物， e。冬虫夏草，牛蒡子，枸杞，黄芪，水蛭，茯苓，枸杞，枸杞子，枸杞子，枸杞子，枸杞子，白术，白术，黄连，葛根和Rehmaniae radix crudae。除了17种主要天然药物之外，如果需要，本发明的组合物可以含有一种或多种补充天然药物，其选自由Liriopsis tuber，Cistanchis herba，Adenophorae radix，Salviae radix，Ginseng radix rubra，Anemarrhenae 根瘤菌，双子叶真菌，黄柏属皮质，山茱萸皮，五味子，五味子，天竺葵，枸杞，枸杞，茯苓，茯苓，枸杞，玛格丽特和壁虎。本发明的组合物是通过降低糖尿病患者的血糖水平，但不降低正常人的血糖水平，降低血脂水平，来预防糖尿病，预防和治疗伴随糖尿病并发症的药剂因此，对于治疗非胰岛素依赖性糖尿病（II型糖尿病）以及胰岛素依赖性糖尿病（I型糖尿病）是特别有效的。

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