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1. 发明授权

US06534281B2 Immunoassay for measuring human C-peptide and kit therefor 有权
公开(公告)号：US06534281B2
公开(公告)日：2003-03-18
申请号：US09878380
申请日：2001-06-12
申请人： Sachiko Kitajima , Yoshihiro Kurano , Kaoru Nakatsubo , Isao Nishizono
发明人： Sachiko Kitajima , Yoshihiro Kurano , Kaoru Nakatsubo , Isao Nishizono
IPC分类号： C07K1400
CPC分类号： G01N33/74 , G01N2333/62 , Y10S436/80 , Y10S436/809 , Y10S436/811 , Y10T436/25125
摘要： An immunoassay for selectively measuring human C-peptide as well as a kit therefor is disclosed. In the method, human C-peptide contained in a sample, a first anti-human C-peptide antibody, and a second anti-human C-peptide antibody which is immobilized on a solid support are reacted to form an immune complex among these three components. The formed immune complex is separated from the non-reacted antibodies and sample; and then the separated immune complex is quantified. The first antibody recognizes an epitope existing in the region from 1st to 16th amino acid residue from the N-terminal of the human C-peptide, and the second antibody recognizes an epitope existing in the region from 1st to 16th amino acid residue from the N-terminal of human C-peptide; with the proviso that the first and second antibodies do not recognize the same epitope so that they can simultaneously bind to said human C-peptide.

2. 发明授权

US07504173B2 Constituent part for fuel cell 有权
标题翻译：燃料电池组成部分
公开(公告)号：US07504173B2
公开(公告)日：2009-03-17
申请号：US10275282
申请日：2001-05-22
申请人： Yuichi Kuroki , Yoshihiro Kurano , Tomohiro Inoue
发明人： Yuichi Kuroki , Yoshihiro Kurano , Tomohiro Inoue
IPC分类号： H01M8/02 , H01M2/08 , H01M4/96 , H01M4/94
CPC分类号： H01M8/0234 , H01M8/0213 , H01M8/0271 , H01M8/0276 , H01M8/0284 , H01M8/0286 , H01M8/1004 , H01M2008/1095
摘要： In order to provide a constituting part for a fuel battery in which a number of steps of assembling the constituting parts for the fuel battery can be reduced, and in which the replacing property and the maintenance property of fuel battery cell parts can be improved and the cost for parts can be reduced, the structure is made such that a separator made of a carbon plate or substantially similar material, a gas diffusion layer made of a carbon fiber or substantially similar material, and a gasket made of a liquid rubber cured material or substantially similar material are integrally formed, and further, gaskets are respectively provided on both surfaces of a pair of gas diffusion layers holding an independent electrolyte membrane from both sides thereof between the pair.
摘要翻译：为了提供能够减少组装燃料电池的构成部件的多个步骤的燃料电池的构成部件，能够提高燃料电池单元部件的替换性能和维护性能，可以降低部件成本，其结构使得由碳板或基本相似的材料制成的隔板，由碳纤维或基本上相似的材料制成的气体扩散层和由液体橡胶固化材料制成的垫圈或大致相同的材料一体形成，并且在一对气体扩散层的两面分别设置有保持独立电解质膜的两面的垫圈。

3. 发明申请

US20070148525A1 Gasket 有权
标题翻译：垫片
公开(公告)号：US20070148525A1
公开(公告)日：2007-06-28
申请号：US11708547
申请日：2007-03-14
申请人： Yuichi Kuroki , Kazuhisa Senda , Yoshihiro Kurano , Tomohiro Inoue
发明人： Yuichi Kuroki , Kazuhisa Senda , Yoshihiro Kurano , Tomohiro Inoue
IPC分类号： H01M2/08 , F16J15/02
CPC分类号： H01M8/0276 , F16J15/0818 , F16J15/104 , F16J15/122 , F16J15/123 , F16J2015/085 , F16J2015/0856 , H01M8/0273 , H01M8/0284
摘要： In order to provide a gasket which has a good handling property as a gasket used for a fuel battery or a gasket for an HDD, can be easily integrated with the other end mounting member even in the case that the other end mounting member such as a separator or the like is a material having low strength or a thin plate, and has good mounting workability, a gasket is having a sheet-shaped gasket mounting member provided with a sticking function on one face, and a gasket main body made of a rubber-type elastic member integrated with the sheet-shaped gasket mounting member, and the gasket is mounted to the other end mounting member on the basis of the sticking function of the sheet-shaped gasket mounting member.
摘要翻译：为了提供具有良好的处理性能的垫圈，作为用于燃料电池的垫圈或用于HDD的垫圈，即使在另一端安装构件例如隔板等是具有低强度或薄板的材料，并且具有良好的安装加工性，垫圈具有在一个面上具有粘着功能的片状衬垫安装构件，以及由橡胶制成的衬垫主体与片状衬垫安装构件一体形成的弹性构件，并且基于片状衬垫安装构件的粘附功能将衬垫安装到另一端安装构件。

4. 发明授权

US5306617A Phenytoin derivatives 失效
标题翻译：苯妥英衍生物
公开(公告)号：US5306617A
公开(公告)日：1994-04-26
申请号：US744411
申请日：1991-08-13
申请人： Takafumi Uchida , Hiroshi Ishikawa , Koichi Koyama , Yoshihiro Kurano , Yoshiaki Uchida
发明人： Takafumi Uchida , Hiroshi Ishikawa , Koichi Koyama , Yoshihiro Kurano , Yoshiaki Uchida
IPC分类号： C12Q1/68 , C07H19/10 , C07H21/00 , C07H5/04 , C07H17/00 , C07H19/06
CPC分类号： C07H21/00
摘要： A phenytoin derivative represented by formula (I) ##STR1## wherein Ph denotes a phenyl group,X denotes --O--, --NH-- or --CH.sub.2 --,Y denotes --CO-- or --CH.sub.2 --,Z denotes a hydrogen atom or a hydroxyl group,M denotes a salt-forming cation, andm and n are each an integer of 0 to 8 and m+n is at least 2.Said compound is useful to produce a phenytoin-labelled DNA or RNA probe. When using such a probe, DNA or RNA in the specimen can be detected with high sensitivity.
摘要翻译：式（I）表示的苯妥英衍生物（*化学结构*）（I）（*化学结构*）其中Ph表示苯基，X表示-O-，-NH-或-CH2-，Y表示-CO- 或-CH 2 - ，Z表示氢原子或羟基，M表示形成盐的阳离子，m和n各自为0至8的整数，m + n至少为2.所述化合物可用于产生苯妥英标记的DNA或RNA探针。当使用这样的探针时，可以高灵敏度地检测样品中的DNA或RNA。

5. 发明授权

US08628894B2 Fuel cell sealing structure comprising stepped gas diffusion layers 有权
标题翻译：包括阶梯式气体扩散层的燃料电池密封结构
公开(公告)号：US08628894B2
公开(公告)日：2014-01-14
申请号：US13124032
申请日：2009-10-06
申请人： Toshihiro Shimazoe , Yoshihiro Kurano , Shigeru Watanabe
发明人： Toshihiro Shimazoe , Yoshihiro Kurano , Shigeru Watanabe
IPC分类号： H01M8/02 , H01M8/10
CPC分类号： H01M8/0276 , H01M8/0258 , H01M8/0284 , H01M2008/1095
摘要： To effectively prevent deformation of an MEA and shift of GDLs, first GDLs, second GDLs, and separators are layered in order at both sides of the MEA in the thickness direction thereof, the gaskets which sandwich an end portion of the MEA outside the first GDLs and the second GDLs are made from rubber or a synthetic resin material having rubber-like elasticity and integrally provided on the separators respectively, the first GDLs have end portions which are formed so as to protrude beyond outer peripheries of the second GDLs, and the gaskets have support step portions which can position and support the end portions of the first GDLs at the same height as the support height by the second GDLs.
摘要翻译：为了有效地防止MEA的变形和GDL的移动，在MEA的厚度方向上的第一GDL，第二GDL和分离器的顺序层叠，在第一GDL之外夹着MEA的端部的垫圈并且第二GDL由橡胶或具有橡胶状弹性的合成树脂材料制成，并且分别一体地设置在隔板上，第一GDL具有形成为突出超过第二GDL的外周的端部，并且垫圈具有能够通过第二GDL以与支撑高度相同的高度来定位和支撑第一GDL的端部的支撑台阶部分。

6. 发明申请

US20120107718A1 FUEL CELL SEALING STRUCTURE 有权
标题翻译：燃料电池密封结构
公开(公告)号：US20120107718A1
公开(公告)日：2012-05-03
申请号：US13378642
申请日：2010-05-27
申请人： Takeshi Masaka , Yoshihiro Kurano , Shinichiro Taguchi , Kenichi Kikuchi , Tetsuya Urakawa
发明人： Takeshi Masaka , Yoshihiro Kurano , Shinichiro Taguchi , Kenichi Kikuchi , Tetsuya Urakawa
IPC分类号： H01M8/02 , H01M8/10
CPC分类号： H01M8/0273 , H01M8/0202 , H01M8/0247 , H01M8/0267 , H01M8/0276 , H01M8/0284 , H01M8/04029 , H01M8/1007 , Y02E60/521
摘要： A fuel cell sealing structure has a power generating body, and first and second separators arranged in both sides in a thickness direction of the power generating body. On a surface in one side in a thickness direction of the first separator, formed integrally first and second sealing protrusions respectively brought into close contact with an outer peripheral portion of the power generating body and the second separator in an outer peripheral side of the first sealing protrusion, and a short circuit prevention rib protruding in line with the first and second sealing protrusions by an electrically insulating rubber-like elastic material. On a surface in another side thereof, formed integrally a third sealing protrusion brought into close contact with a surface in an opposite side to the power generating body in the second separator, by the electrically insulating rubber-like elastic material.
摘要翻译：燃料电池密封结构具有发电体，并且在发电体的厚度方向上的两侧配置有第一和第二隔板。在第一隔板的厚度方向的一侧的表面上，一体地形成有第一密封突起和第二密封突起，分别在第一密封件的外周侧与发电体的外周部和第二隔板紧密接触突出部以及通过电绝缘橡胶状弹性材料与第一密封突起和第二密封突起一直突出的防短路肋。在其另一侧的表面上，通过电绝缘橡胶状弹性材料一体地形成与第二隔板中的发电体相反侧的表面紧密接触的第三密封突起。

7. 发明授权

US07829238B2 Fuel cell having a gasket integrally formed through gas diffusion layer 有权
标题翻译：具有通过气体扩散层一体形成的垫圈的燃料电池
公开(公告)号：US07829238B2
公开(公告)日：2010-11-09
申请号：US11783972
申请日：2007-04-13
申请人： Yuichi Kuroki , Yoshihiro Kurano , Tomohiro Inoue , Atsushi Oma , Yasuji Ogami , Kazuo Saito
发明人： Yuichi Kuroki , Yoshihiro Kurano , Tomohiro Inoue , Atsushi Oma , Yasuji Ogami , Kazuo Saito
IPC分类号： H01M2/08 , H01M4/94 , H01M8/02
CPC分类号： H01M8/0286 , H01M8/023 , H01M8/0247 , H01M8/0271 , H01M8/0276 , H01M8/0284 , H01M2008/1095 , Y02P70/56
摘要： In order to prevent an electrolyte membrane from being broken, and make an assembling steps of a cell easy, in a fuel cell provided with a membrane electrode complex in which catalyst layers are respectively arranged on both surfaces of a electrolyte membrane, first and second gas diffusion layers which are arranged on both surfaces of the electrode complex, separators for respectively supplying reaction gas to the first and second gas diffusion layers, and a gasket for sealing the reaction gas, the gasket is formed on a surface of the gas diffusion layer so as to oppose to the separator, at least the gasket forming portion of the gas diffusion layer has a lower void content than the portion in contact with the catalyst layer, and the gasket arranged in the first and second gas diffusion layers is integrally formed at least via a through hole passing through the first and second gas diffusion layers.
摘要翻译：为了防止电解质膜破裂，并且容易地进行电池的组装步骤，在具有膜电极复合体的燃料电池中，其中催化剂层分别设置在电解质膜的两个表面上，第一和第二气体布置在电极复合体的两个表面上的扩散层，用于分别向第一和第二气体扩散层供应反应气体的隔板和用于密封反应气体的垫圈，在气体扩散层的表面上形成垫圈，为了与隔板相对，至少气体扩散层的垫圈形成部分具有比与催化剂层接触的部分更低的空隙含量，并且布置在第一和第二气体扩散层中的衬垫至少一体地形成通过穿过第一和第二气体扩散层的通孔。

8. 发明授权

US06291198B1 Antibody that recognizes pyrazine derivative and method for measuring 1,2-dicarbonyl derivative using said antibody 失效
标题翻译：识别吡嗪衍生物的抗体和使用所述抗体测量1,2-二羰基衍生物的方法
公开(公告)号：US06291198B1
公开(公告)日：2001-09-18
申请号：US09134388
申请日：1998-08-14
申请人： Yoshiaki Uchida , Yoshihiro Kurano , Satoru Ito
发明人： Yoshiaki Uchida , Yoshihiro Kurano , Satoru Ito
IPC分类号： G01N33545
CPC分类号： G01N33/5308 , C07K16/44 , G01N33/6893 , Y10S530/807
摘要： A method for simply measuring a 1,2-dicarbonyl derivative in multiple specimens is provided, which comprises converting a 1,2-dicarbonyl derivative to a pyrazine derivative represented by the formula (I): wherein R1 and R2 independently represent a hydrogen atom, a methyl group, a hydroxymethyl group, a hydroxyethyl group, a dihydroxyethyl group, a dihydroxypropyl group, a trihydroxypropyl group, or a trihydroxybutyl group, A represents a group that binds to the pyrazine ring to form a 6-membered aromatic hydrocarbon group, a 5- or 6-membered aromatic heterocyclic group, or a 5- or 6-membered alicyclic hydrocarbon group, and R3 represents a linking residue, wherein said 5-membered ring formed by A may have 1 or 2 substituents and said 6-membered ring may have 1 to 3 substituents, in addition to R3 and measuring the pyrazine derivative by an immunological method using an antibody that recognizes the pyrazine derivative.
摘要翻译：提供简单测定多个试样中的1,2-二羰基衍生物的方法，其包括将1,2-二羰基衍生物转化为由式（I）表示的吡嗪衍生物：其中R1和R2独立地表示氢原子，甲基，羟甲基，羟乙基，二羟基乙基，二羟丙基，三羟基丙基或三羟基丁基，A表示与吡嗪环结合形成6元芳族烃基的基团， 5元或6元芳族杂环基，或5元或6元脂环烃基，R3表示连接残基，其中由A形成的所述5元环可以具有1或2个取代基，所述6元环除了R3之外还可以具有1至3个取代基，并且通过使用识别吡嗪衍生物的抗体的免疫学方法测量吡嗪衍生物。

9. 发明授权

US09269967B2 Gasket 有权
标题翻译：垫片
公开(公告)号：US09269967B2
公开(公告)日：2016-02-23
申请号：US13700578
申请日：2011-05-26
申请人： Takeshi Masaka , Yoshihiro Kurano , Shotaro Koga
发明人： Takeshi Masaka , Yoshihiro Kurano , Shotaro Koga
IPC分类号： H01M8/02 , F16J15/10 , H01M2/08
CPC分类号： H01M8/0271 , F16J15/104 , H01M2/08 , H01M8/0273 , H01M8/0276 , H01M8/0286 , Y02E60/50
摘要： Provided is a gasket which can improve a handling property of the gasket by enhancing a rigidity of a carrier, can secure a space saving without increasing a thickness of the gasket, and can improve a yield ratio of a resin material, in the gasket of a type that a gasket body is integrated with the resin carrier. A planar gasket used by being pinched between two members superposed with each other has a gasket body achieving a seal action, and a carrier retaining the gasket body, the carrier is formed as a predetermined planar shape by a metal mold with a resin material, and is formed as a stepped shape by setting a partial portion which is superposed with the gasket body on a plane to a thin portion, and setting the other portion which is not superposed with the gasket body on the plane to a thick portion.
摘要翻译：提供一种垫圈，其可以通过增强载体的刚性来改善垫圈的操作性能，可以在不增加垫圈厚度的情况下确保节省空间，并且可以提高垫圈中的树脂材料的屈服比表示垫片主体与树脂载体一体化。通过夹在两个彼此重叠的部件之间使用的平面垫圈具有实现密封作用的垫圈主体和保持垫圈主体的托架，托架通过具有树脂材料的金属模形成为预定的平面形状，并且通过将与衬垫体重叠的局部部分设置在平面上而形成为台阶形状，并将其与垫圈主体不重叠的另一部分设置在厚度部分上。

10. 发明申请

US20130065158A1 GASKET 有权
标题翻译：垫子
公开(公告)号：US20130065158A1
公开(公告)日：2013-03-14
申请号：US13700578
申请日：2011-05-26
申请人： Takeshi Masaka , Yoshihiro Kurano , Shotaro Koga
发明人： Takeshi Masaka , Yoshihiro Kurano , Shotaro Koga
IPC分类号： H01M8/02 , H01M2/08
CPC分类号： H01M8/0271 , F16J15/104 , H01M2/08 , H01M8/0273 , H01M8/0276 , H01M8/0286 , Y02E60/50
摘要： Provided is a gasket which can improve a handling property of the gasket by enhancing a rigidity of a carrier, can secure a space saving without increasing a thickness of the gasket, and can improve a yield ratio of a resin material, in the gasket of a type that a gasket body is integrated with the resin carrier. A planar gasket used by being pinched between two members superposed with each other has a gasket body achieving a seal action, and a carrier retaining the gasket body, the carrier is formed as a predetermined planar shape by a metal mold with a resin material, and is formed as a stepped shape by setting a partial portion which is superposed with the gasket body on a plane to a thin portion, and setting the other portion which is not superposed with the gasket body on the plane to a thick portion.
摘要翻译：提供一种垫圈，其可以通过增强载体的刚性来改善垫圈的操作性能，可以在不增加垫圈厚度的情况下确保节省空间，并且可以提高垫圈中的树脂材料的屈服比表示垫片主体与树脂载体一体化。通过夹在两个彼此重叠的部件之间使用的平面垫圈具有实现密封作用的垫圈主体和保持垫圈主体的托架，托架通过具有树脂材料的金属模形成为预定的平面形状，并且通过将与衬垫体重叠的局部部分设置在平面上而形成为台阶形状，并将其与垫圈主体不重叠的另一部分设置在厚度部分上。

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