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    • 2. 发明授权
    • Solid phase extraction apparatus
    • 固相萃取装置
    • US5439593A
    • 1995-08-08
    • US158179
    • 1993-11-23
    • Thomas E. Price
    • Thomas E. Price
    • B01D15/00B01D15/08G01N30/00G01N30/60G01N30/84
    • B01D15/08B01D15/22G01N30/6091G01N2030/009
    • Apparatus for retaining a sorbent bed without permitting voids to be created and that can be readily handled by automated systems is disclosed. A solid phase extraction apparatus is disclosed that is most preferably comprised of a body that contains a sorbent bed and a cap that forms an axial sliding seal with the body. A sleeve is provided to retain the body and create an outside geometry similar to that of a standard glass vial. The sliding seal permits voids in the sorbent bed to be eliminated by axial compressive sealing forces. In a most preferred embodiment, conical sealing surfaces are provided at each end of the disclosed cartridge to facilitate removal of the cartridge after the axial sealing forces are released. The cap and the body are also provided with surfaces compatible with luer fittings, that provide flexibility and permit the use of the invention with existing fluid flow systems.
    • 公开了用于保持吸附剂床而不允许产生空隙并且可以由自动化系统容易地处理的装置。 公开了一种固相萃取装置,其最优选由包含吸附剂床和与主体形成轴向滑动密封的盖体构成。 提供套筒以保持身体并产生类似于标准玻璃小瓶的外部几何形状。 滑动密封允许通过轴向压缩密封力消除吸附剂床中的空隙。 在最优选的实施例中,锥形密封表面设置在所公开的盒的每个端部处,以便在释放轴向密封力之后便于移除盒。 盖和主体还具有与鲁尔接头相容的表面,其提供柔性并且允许本发明与现有的流体流动系统一起使用。