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1. 发明授权

US07435221B1 System and method for detecting abnormal respiration based on intracardiac electrogram signals using a pattern recognition device 有权
标题翻译：使用模式识别装置，基于心内电描记信号检测异常呼吸的系统和方法
公开(公告)号：US07435221B1
公开(公告)日：2008-10-14
申请号：US11558819
申请日：2006-11-10
申请人： Rupinder Bharmi , Philip de Chazal , Gene A. Bornzin , Michael E. Benser
发明人： Rupinder Bharmi , Philip de Chazal , Gene A. Bornzin , Michael E. Benser
IPC分类号： A61B5/08 , A61B5/02 , A61B5/04
CPC分类号： A61B5/0452 , A61B5/0031 , A61B5/02405 , A61B5/0472 , A61B5/08 , A61B5/0803 , A61B5/0816 , A61B5/11 , A61B5/145 , A61B5/411 , A61B5/4818 , A61B5/7267 , A61N1/3601 , A61N1/365 , A61N1/37
摘要： Techniques are provided for detecting abnormal respiration within a patient based upon intracardiac electrogram (IEGM) signals or other electrical cardiac signals. Briefly, abnormal respiration is detected using a pattern recognition trained to discriminate normal and abnormal respiration based on morphological parameters and interval-based parameters extracted from the IEGM signals. In addition, techniques are described for distinguishing among different cardiac rhythm types within the patient while using one or more pattern classifiers or other pattern recognition devices.
摘要翻译：提供了用于基于心内电描记图（IEGM）信号或其他电心脏信号来检测患者内异常呼吸的技术。简而言之，使用根据从IEGM信号提取的形态参数和基于间隔的参数来鉴别正常和异常呼吸的训练的模式识别来检测异常呼吸。此外，描述了用于在使用一个或多个模式分类器或其他模式识别装置的同时区分患者内的不同心律类型之类的技术。

2. 发明授权

US07862515B2 Apparatus for detecting sleep apnea using electrocardiogram signals 有权
标题翻译：使用心电图信号检测睡眠呼吸暂停的装置
公开(公告)号：US07862515B2
公开(公告)日：2011-01-04
申请号：US11308429
申请日：2006-03-24
申请人： Philip de Chazal , Conor Heneghan , Elaine Sheridan
发明人： Philip de Chazal , Conor Heneghan , Elaine Sheridan
IPC分类号： A61B5/0402
CPC分类号： A61B5/4818 , A61B5/04325 , A61B5/0456 , A61B5/7203 , A61B5/7207 , A61B5/7264 , A61B5/7267 , G06F19/00 , G16H50/20
摘要： An apparatus for diagnosing sleep apnea only uses an electrocardiogram signal and a computer processor and associated computer code that are configured to analyze the electrocardiogram signal and classify each time period of the electrocardiogram signal as either apneic or normal. A diagnostic measure of sleep apnea for the human patient is provided based on classification results obtained by combining a results for various electrocardiogram signal time periods. A computer-readable medium has computer code that causes the computer to analyze an electrocardiogram signal relating to the human patient and classify each time period in a set of time periods as either apneic or normal. A diagnostic measure of sleep apnea is provided based on classification results obtained by combining a plurality of results from the set of time periods using either time or frequency domain processing, or both.
摘要翻译：用于诊断睡眠呼吸暂停的装置仅使用心电图信号和计算机处理器以及相关联的计算机代码，其被配置为分析心电图信号并将心电图信号的每个时间段分类为呼吸暂停或正常。基于通过组合各种心电图信号时间段的结果而获得的分类结果，提供了针对人类患者的睡眠呼吸暂停的诊断测量。计算机可读介质具有计算机代码，该计算机代码使得计算机分析与人类患者有关的心电图信号，并且在一组时间段内将呼吸暂停或正常的每个时间段分类。基于通过使用时间或频域处理组合来自所述一组时间段的多个结果或两者来获得的分类结果来提供睡眠呼吸暂停的诊断测量。

3. 发明申请

US20060184056A1 APPARATUS FOR DETECTING SLEEP APNEA USING ELECTROCARDIOGRAM SIGNALS 有权
标题翻译：使用电子信号检测睡眠APNEA的装置
公开(公告)号：US20060184056A1
公开(公告)日：2006-08-17
申请号：US11308429
申请日：2006-03-24
申请人： Philip de Chazal , Conor Heneghan , Elaine Sheridan
发明人： Philip de Chazal , Conor Heneghan , Elaine Sheridan
IPC分类号： A61B5/04
CPC分类号： A61B5/4818 , A61B5/04325 , A61B5/0456 , A61B5/7203 , A61B5/7207 , A61B5/7264 , A61B5/7267 , G06F19/00 , G16H50/20
摘要： An apparatus for diagnosing sleep apnea only uses an electrocardiogram signal and a computer processor and associated computer code that are configured to analyze the electrocardiogram signal and classify each time period of the electrocardiogram signal as either apneic or normal. A diagnostic measure of sleep apnea for the human patient is provided based on classification results obtained by combining a results for various electrocardiogram signal time periods. A computer-readable medium has computer code that causes the computer to analyze an electrocardiogram signal relating to the human patient and classify each time period in a set of time periods as either apneic or normal. A diagnostic measure of sleep apnea is provided based on classification results obtained by combining a plurality of results from the set of time periods using either time or frequency domain processing, or both.
摘要翻译：用于诊断睡眠呼吸暂停的装置仅使用心电图信号和计算机处理器以及相关联的计算机代码，其被配置为分析心电图信号并将心电图信号的每个时间段分类为呼吸暂停或正常。基于通过组合各种心电图信号时间段的结果而获得的分类结果，提供了针对人类患者的睡眠呼吸暂停的诊断测量。计算机可读介质具有计算机代码，该计算机代码使得计算机分析与人类患者有关的心电图信号，并且在一组时间段内将呼吸暂停或正常的每个时间段分类。基于通过使用时间或频域处理组合来自所述一组时间段的多个结果或两者来获得的分类结果来提供睡眠呼吸暂停的诊断测量。

4. 发明授权

US07025729B2 Apparatus for detecting sleep apnea using electrocardiogram signals 有权
公开(公告)号：US07025729B2
公开(公告)日：2006-04-11
申请号：US09952688
申请日：2001-09-14
申请人： Philip de Chazal , Conor Heneghan , Elaine Sheridan
发明人： Philip de Chazal , Conor Heneghan , Elaine Sheridan
IPC分类号： A61B5/0402
CPC分类号： A61B5/4818 , A61B5/04325 , A61B5/0456 , A61B5/7203 , A61B5/7207 , A61B5/7264 , A61B5/7267 , G06F19/00 , G16H50/20
摘要： There is provided a method of determining a diagnostic measure of sleep apnea including the following steps: acquiring an electrocardiogram signal, calculating a set of RR intervals and electrocardiogram-derived respiratory signal from said electrocardiogram, and hence calculating a set of spectral and time-domain measurements over time periods including power spectral density, mean, and standard deviation. These measurements are processed by a classifier model which has been trained on a pre-existing data base of electrocardiogram signals to provide a probability of a specific time period containing apneic episodes or otherwise. These probabilities can be combined to form an overall diagnostic measure. The system also provides a system and apparatus for providing a diagnostic measure of sleep apnea.

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