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1. 发明授权

US4636194A Burr-hole flow control valve 失效
标题翻译：钻孔流量控制阀
公开(公告)号：US4636194A
公开(公告)日：1987-01-13
申请号：US796299
申请日：1985-11-08
申请人： Rudolf R. Schulte , Gary P. East , Marga M. Bryant , Alfons Heindl
发明人： Rudolf R. Schulte , Gary P. East , Marga M. Bryant , Alfons Heindl
IPC分类号： A61M27/00 , A61M5/00
CPC分类号： A61M27/006
摘要： A surgically implantable flow control valve positionable over a burr-hole through a patient's skull is provided for use in shunt systems for controlling the release of entrapped body fluids. The valve includes a relatively rigid, unitized molded plastic base having a planar valve seat portion, an inlet passageway through the base which terminates at an inlet port situated within the planar valve seat portion of the base, a resilient membrane which is molded of a material different from the material of the plastic base and which is secured to the base in a manner surrounding and covering the inlet port, and an outlet separated from the inlet by the resilient membrane. Radiopaque indicators and markers are provided which permit a surgeon to ascertain specific information about the device and the functioning of the shunt system which would otherwise be unavailable without additional surgery.
摘要翻译：提供了一种通过患者颅骨定位在钻孔上方的手术可植入流量控制阀，用于分流系统中，用于控制截留体液的释放。该阀包括相对刚性的组合成型的塑料底座，其具有平面阀座部分，通过底座的入口通道，其终止于位于基座的平面阀座部分内的入口端口，弹性膜由材料模制不同于塑料基底的材料，并且以围绕和覆盖入口的方式固定到基部，以及通过弹性膜与入口分离的出口。提供了不透射线的指示器和标记，其允许外科医生确定关于装置的特定信息和分流系统的功能，否则在没有另外的手术的情况下将不可用。

2. 发明授权

US4552553A Flow control valve 失效
标题翻译：流量控制阀
公开(公告)号：US4552553A
公开(公告)日：1985-11-12
申请号：US574997
申请日：1984-01-30
申请人： Rudolf R. Schulte , Gary P. East , Marga M. Bryant , Alfons Heindl
发明人： Rudolf R. Schulte , Gary P. East , Marga M. Bryant , Alfons Heindl
IPC分类号： A61M27/00 , A61M39/00 , A61M5/00
CPC分类号： A61M27/006
摘要： For use in controlling the release of entrapped body fluids, a surgically implantable flow control valve is provided which includes a molded plastic base separating an inlet chamber from an outlet chamber and including one or more apertures passing from the inlet chamber to the outlet chamber, and a resilient membrane which is molded of a material different from the material of the plastic base and which is secured to the base covering the aperture or apertures through the base on the outlet chamber side of the base.
摘要翻译：为了用于控制捕获的体液的释放，提供了一种手术可植入的流量控制阀，其包括将入口室与出口室分隔开并包括从入口室通向出口腔室的一个或多个孔的模制塑料基座，以及弹性膜由不同于塑料基材的材料的材料模制，并且固定到覆盖孔或孔的底座上，穿过底座的出口腔侧。

3. 发明授权

US4761158A Subcutaneous infusion reservoir and pump system 失效
标题翻译：皮下输液槽和泵系统
公开(公告)号：US4761158A
公开(公告)日：1988-08-02
申请号：US75332
申请日：1987-07-20
申请人： Rudolf R. Schulte , Gary P. East , Alfons Heindl
发明人： Rudolf R. Schulte , Gary P. East , Alfons Heindl
IPC分类号： A61M5/142 , A61M5/00
CPC分类号： A61M5/1428
摘要： A totally subcutaneously implantable infusion reservoir and pump system includes a variable capacity reservoir for receiving and storing fluid medication for delivery to a catheter which directs the medication to a specific infusion location in the body. In a preferred form of the invention, a control assembly is interposed between the reservoir and the catheter to facilitate and control the transfer of the medication from the reservoir to the catheter in a safe and efficient manner. This control assembly includes a normally closed valve and a pump, both of which are manually actuable by percutaneous pressure when subcutaneously implanted, and defines a portion of a fluid flow conduit between the reservoir and the catheter. Moreover, the control assembly is constructed to prevent the backflow of fluid from the catheter to the reservoir, as well as the unrestricted flow of medication through the control assembly when the normally closed valve is opened. This is accomplished by requiring at least two deliberate and sequential applications of selective pressure to the control assembly before any medication stored in the reservoir can be transferred to the catheter.
摘要翻译：完全皮下植入的输注储液器和泵系统包括可变容量储存器，用于接收和存储流体药物以输送到导管，其将药物引导至身体中的特定输注位置。在本发明的优选形式中，控制组件插入在储存器和导管之间，以便以安全和有效的方式促进和控制药物从储存器转移到导管。该控制组件包括常闭阀和泵，当皮下注入时，它们都可通过经皮压力手动地致动，并限定储液器和导管之间的一部分流体流动导管。此外，控制组件被构造成防止流体从导管向贮存器的回流，以及当常开的阀打开时通过控制组件的药物的不受限制的流动。这是通过在存储在储存器中的任何药物可以转移到导管之前要求至少两次故意和顺序地施加选择性压力来实现的。

4. 发明授权

US4560375A Flow control valve 失效
标题翻译：流量控制阀
公开(公告)号：US4560375A
公开(公告)日：1985-12-24
申请号：US575165
申请日：1984-01-30
申请人： Rudolf R. Schulte , Gary P. East , Marga M. Bryant , Alfons Heindl
发明人： Rudolf R. Schulte , Gary P. East , Marga M. Bryant , Alfons Heindl
IPC分类号： A61M27/00 , A61M5/00
CPC分类号： A61M27/006
摘要： A surgically implantable flow control valve is provided for use in shunt systems for controlling the release of entrapped body fluids. The valve includes a relatively rigid, unitized molded plastic base separating an inlet chamber from an outlet chamber and including one or more apertures passing from the inlet chamber to the outlet chamber, and a resilient membrane which is molded of a material different from the material of the plastic base and which is secured to the base in a manner covering the apertures through the base on the outlet chamber side of the base. Fluid flow occluders on the base facilitate both proximal and distal flushing, and radiopaque indicators and markers permit a surgeon to ascertain specific information about the device and the functioning of the shunt system which would otherwise be unavailable without additional surgery.
摘要翻译：提供外科可植入的流量控制阀，用于分流系统中用于控制截留的体液的释放。该阀包括相对刚性的组合模制塑料底座，其将入口室与出口室分隔开并且包括从入口室通向出口室的一个或多个孔，以及弹性膜，其由不同于塑料基座，并以覆盖基座的方式通过底座的出口腔侧固定到基座上。基座上的流体阻塞器便于近端和远端冲洗，并且不透射线的指示器和标记允许外科医生确定关于装置的特定信息和分流系统的功能，否则在没有另外的手术的情况下将不可用。

5. 发明授权

US4816016A Subcutaneous infusion reservoir and pump system 失效
标题翻译：皮下输液槽和泵系统
公开(公告)号：US4816016A
公开(公告)日：1989-03-28
申请号：US170271
申请日：1988-03-18
申请人： Rudolf R. Schulte , Gary P. East , Alfons Heindl
发明人： Rudolf R. Schulte , Gary P. East , Alfons Heindl
IPC分类号： A61M5/142 , A61M5/00
CPC分类号： A61M5/1428
摘要： A totally subcutaneously implantable infusion reservoir and pump system includes a variable capacity reservoir for receiving and storing fluid medication for delivery to a catheter which directs the medication to a specific infusion location in the body. In a preferred form of the invention, a control assembly is interposed between the reservoir and the catheter to facilitate and control the transfer of the medication from the reservoir to the catheter in a safe and efficient manner. This control assembly includes a normally closed valve and a pump, both of which are manually actuable by percutaneous pressure when subcutaneously implanted, and defines a portion of a fluid flow conduit between the reservoir and the catheter. Moreover, the control assembly is constructed to prevent the backflow of fluid from the catheter to the reservoir, as well as the unrestricted flow of medication through the control assembly when the normally closed valve is opened. This is accomplished by requiring at least two deliberate and sequential applications of selective pressure to the control assembly before any medication stored in the reservoir can be transferred to the catheter.
摘要翻译：完全皮下植入的输注储液器和泵系统包括可变容量储存器，用于接收和存储流体药物以输送到导管，其将药物引导至身体中的特定输注位置。在本发明的优选形式中，控制组件插入在储存器和导管之间，以便以安全和有效的方式促进和控制药物从储存器转移到导管。该控制组件包括常闭阀和泵，当皮下注入时，它们都可通过经皮压力手动地致动，并限定储液器和导管之间的一部分流体流动导管。此外，控制组件被构造成防止流体从导管向贮存器的回流，以及当常开的阀打开时通过控制组件的药物的不受限制的流动。这是通过在存储在储存器中的任何药物可以转移到导管之前要求至少两次故意和顺序地施加选择性压力来实现的。

6. 发明授权

US4681560A Subcutaneous infusion reservoir and pump system 失效
公开(公告)号：US4681560A
公开(公告)日：1987-07-21
申请号：US850943
申请日：1986-04-11
申请人： Rudolf R. Schulte , Gary P. East , Alfons Heindl
发明人： Rudolf R. Schulte , Gary P. East , Alfons Heindl
IPC分类号： A61M5/142 , A61M5/00
CPC分类号： A61M5/1428
摘要： A totally subcutaneously implantable infusion reservoir and pump system includes a variable capacity reservoir for receiving and storing fluid medication for delivery to a catheter which directs the medication to a specific infusion location in the body. In a preferred form of the invention, a control assembly is interposed between the reservoir and the catheter to facilitate and control the transfer of the medication from the reservoir to the catheter in a safe and efficient manner. This control assembly includes a normally closed valve and a pump, both of which are manually actuable by percutaneous pressure when subcutaneously implanted, and defines a portion of a fluid flow conduit between the reservoir and the catheter. Moreover, the control assembly is constructed to prevent the backflow of fluid from the catheter to the reservoir, as well as the unrestricted flow of medication through the control assembly when the normally closed valve is opened. This is accomplished by requiring at least two deliberate and sequential applications of selective pressure to the control assembly before any medication stored in the reservoir can be transferred to the catheter.

7. 外观设计

USD273993S Catheter clip 失效
公开(公告)号：USD273993S
公开(公告)日：1984-05-22
申请号：US346367
申请日：1982-02-05
申请人： Rudolf R. Schulte , Alfons Heindl
设计人： Rudolf R. Schulte , Alfons Heindl

8. 发明授权

US4861331A Implantable shunt system and method of assembly 失效
标题翻译：可植入分流系统及组装方法
公开(公告)号：US4861331A
公开(公告)日：1989-08-29
申请号：US184749
申请日：1988-04-22
申请人： Gary P. East , Stephen W. Laguette , Alfons Heindl , Leanne M. Lintula
发明人： Gary P. East , Stephen W. Laguette , Alfons Heindl , Leanne M. Lintula
IPC分类号： A61M25/00 , A61M1/00 , A61M27/00 , F16K15/14
CPC分类号： A61M27/006 , F16K15/148 , Y10T137/789
摘要： A surgically implantable shunt system, including a flow control valve and an antechamber, is provided for controlling the release of entrapped body fluids. The flow control valve includes a pair of molded plastic bases situated, respectively, adjacent to an inlet and an outlet of the valve, which bases are situated within a flexible encasement. Each base includes an outer housing, a valve membrane carrier positioned within the housing, and a flow control member. The flow control members each include a rigid nail-like central support and a separate flexible resilient membrane positioned on the central support. A first flow control member is capable of selectively occluding the valve inlet, but is normally spaced from its base to permit free fluid flow through the inlet. The second flow control member is generally arch-shaped and resiliently biased to contact its respective base generally along the outer edge of the membrane in a manner permitting only controlled one-way flow through the valve. The antechamber permits injection of medication into the shunt between a proximal catheter and the distal flow control valve, and pumping of the medication in either direction. Additionally, a method for assembling the shunt system in a quick and economical manner is provided, which utilizes tapered grommets to anchor components in place prior to adhesively securing tubing to the flexible encasement.

9. 发明授权

US4995856A Ventriculostomy reservoir 失效
标题翻译：脑室造影术
公开(公告)号：US4995856A
公开(公告)日：1991-02-26
申请号：US365906
申请日：1989-06-14
申请人： Alfons Heindl , Stephen W. Laguette , Leanne M. Lintula
发明人： Alfons Heindl , Stephen W. Laguette , Leanne M. Lintula
IPC分类号： A61M37/00 , A61M1/00 , A61M27/00
CPC分类号： A61M27/006
摘要： A ventriculostomy reservoir includes a rigid base and an elastomeric cap which is positioned over the base to enclose a reservoir well. A rigid cap insert is captured by the lower portion of the cap and is positioned for engagement with the base. The cap insert and the base are configured so that the cap may be snap-fit onto the base in a manner forming a fluid-tight seal therebetween. In one form of the invention, the cap insert includes a cylindrical portion which extends downwardly from a flange-like portion captured within the cap, to fit within an upwardly extending wall portion of the base. The cylindrical portion includes an encircling protrusion on an exterior surface thereof which engages and fits within an encircling detent provided on the interior surface of the wall portion to snap-fit the cap to the base. In a second embodiment of the invention the cap insert exteriorly surrounds an upper end of the base, and a similar protrusion and detent arrangement is utilized to snap-fit the cap to the base. In a third embodiment of the invention the cap insert overlies an upper end of the base and is secured to the base through an interference fit both on interior and exterior surfaces of the wall portion of the base.

10. 发明授权

US5137529A Injection port 失效
标题翻译：注射口
公开(公告)号：US5137529A
公开(公告)日：1992-08-11
申请号：US679658
申请日：1991-04-02
申请人： David A. Watson , Mark J. Licata , Alfons Heindl , Edward C. Leicht
发明人： David A. Watson , Mark J. Licata , Alfons Heindl , Edward C. Leicht
IPC分类号： A61M39/02
CPC分类号： A61M39/0208 , A61M2039/0072 , A61M2039/0229 , A61M2039/0241 , A61M2205/32 , Y10S128/12
摘要： A subcutaneously implantable injection port includes an elastomeric outer housing which encloses an easily assemblage multi-piece rigid base structure. An injection chamber is defined between an upper septum, formed integrally with the elastomeric outer housing, and the underlying base structure. The outer housing includes an upper dome and a lower reinforced sheet. The septum, which is formed integrally with the upper dome, includes a septum flange which is compressed, interiorly of the outer housing, between two base members. A filter extends across the injection chamber dividing it into upper and lower portions. A needle guard, provided by one of the base components, prevents contact between a needle inserted into the injection chamber and the filter. An outlet connector integrally formed with one of the base components extends through the outer housing for connecting a catheter or the like, with the lower portion of the injection chamber. In assembling the injection port, a first base member or rigid outer ring is placed adjacent to an interior surface of the elastomeric outer housing. A filter is placed within a second base member and held securely in place thereon by a third base member which provides the needle guard and fits within the second base member in an interference fit. This assembly is pushed into the first base member in a manner compressing the septum flange and creating a fluid-tight injection chamber.
摘要翻译：皮下可植入的注射口包括弹性体外壳，其包围容易组装的多片刚性基底结构。注射室限定在与弹性体外壳一体形成的上隔膜和下面的基础结构之间。外壳包括上穹顶和下加强片。与上部圆顶一体形成的隔膜包括在两个基部构件之间被压缩在外部壳体内部的隔膜凸缘。过滤器延伸穿过注射室，将其分成上部和下部。由一个基本部件提供的针护罩防止插入注射室中的针与过滤器之间的接触。与其中一个基座部件整体形成的出口连接件延伸穿过外壳体，用于连接导管等与注射室的下部。在组装注射口时，第一底部构件或刚性外环邻近弹性体外壳的内表面放置。过滤器放置在第二基座构件内并且通过提供针护罩的第三基座构件牢固地保持在适当位置，并以过盈配合装配在第二基座构件内。该组件以压缩隔膜凸缘并产生流体密封的注射室的方式被推入第一基件。

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