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1. 发明授权

US07063944B1 Human methionine synthase reductase: cloning, and methods for evaluating risk of, preventing, or treating neural tube defects, cardiovascular disease, cancer, and down's syndrome 失效
标题翻译：人甲硫氨酸合成酶还原酶：克隆和评估神经管缺陷，心血管疾病，癌症和衰老综合征的风险，预防或治疗的方法
公开(公告)号：US07063944B1
公开(公告)日：2006-06-20
申请号：US09487841
申请日：2000-01-19
申请人： Roy A. Gravel , Rima Rozen , Daniel Leclerc , Aaron Wilson , David Rosenblatt
发明人： Roy A. Gravel , Rima Rozen , Daniel Leclerc , Aaron Wilson , David Rosenblatt
IPC分类号： C12Q1/68 , C12Q1/00 , C12P19/34 , C07H21/04
CPC分类号： C12N9/1007
摘要： The invention features a novel gene encoding methionine synthase reductase. The invention also features a method for detecting an increased likelihood of hyperhomocysteinemia and, in turn, an increased or decreased likelihood of neural tube defects, cardiovascular disease, Down's Syndrome or cancer. The invention also features therapeutic methods for treating and/or reducing the risk of cardiovascular disease, Down's Syndrome, cancer, or neural tube defects. Also provided are the sequences of the human methionine synthase reductase gene and protein and compounds and kits for performing the methods of the invention.
摘要翻译：本发明的特征在于一种编码甲硫氨酸合成酶还原酶的新基因。本发明还特征在于一种用于检测高半胱氨酸血症的可能性增加的方法，反过来，增加或减少了神经管缺陷，心血管疾病，唐氏综合征或癌症的可能性。本发明还具有用于治疗和/或降低心血管疾病唐氏综合征，癌症或神经管缺陷风险的治疗方法。还提供了人甲硫氨酸合酶还原酶基因和蛋白质的序列，以及用于实施本发明方法的化合物和试剂盒。

2. 发明授权

US07045612B2 Human methionine synthase reductase: cloning, and methods for evaluating risk of neural tube defects, cardiovascular disease, and cancer 失效
标题翻译：人甲硫氨酸合成酶还原酶：克隆，评估神经管缺陷，心血管疾病和癌症风险的方法
公开(公告)号：US07045612B2
公开(公告)日：2006-05-16
申请号：US09371347
申请日：1999-08-10
申请人： Roy A. Gravel , Rima Rozen , Daniel Leclerc , Aaron Wilson , David Rosenblatt
发明人： Roy A. Gravel , Rima Rozen , Daniel Leclerc , Aaron Wilson , David Rosenblatt
IPC分类号： C12N15/53 , C12N9/02 , C12N15/00 , C12N5/00 , C12N1/20 , C12Q1/26 , C12P21/06 , C07H21/04
CPC分类号： C12N9/1007
摘要： The invention features a novel gene encoding methionine synthase reductase. The invention also features a method for detecting an increased likelihood of hyperhomocysteinemia and, in turn, an increased or decreased likelihood of neural tube defects, cardiovascular disease, or cancer. The invention also features therapeutic methods for treating and/or reducing the risk of cardiovascular disease, cancer, or neural tube defects. Also provided are the sequences of the human methionine synthase reductase gene and protein and compounds and kits for performing the methods of the invention.
摘要翻译：本发明的特征在于一种编码甲硫氨酸合成酶还原酶的新基因。本发明还特征在于一种用于检测增加的高同型半胱氨酸血症的可能性以及神经管缺陷，心血管疾病或癌症的增加或减少的可能性的方法。本发明还具有用于治疗和/或降低心血管疾病，癌症或神经管缺陷风险的治疗方法。还提供了人甲硫氨酸合酶还原酶基因和蛋白质的序列，以及用于实施本发明方法的化合物和试剂盒。

3. 发明申请

US20050191701A1 Human methionine synthase reductase: cloning, and methods for evaluating risk of neural tube deffects, cardiovascular disease, cancer and Down's Syndrome 审中-公开
标题翻译：人甲硫氨酸合成酶还原酶：克隆和评估神经管的影响，心血管疾病，癌症和唐氏综合征风险的方法
公开(公告)号：US20050191701A1
公开(公告)日：2005-09-01
申请号：US11119096
申请日：2005-04-29
申请人： Roy Gravel , Rima Rozen , Daniel Leclerc , Aaron Wilson , David Rosenblatt
发明人： Roy Gravel , Rima Rozen , Daniel Leclerc , Aaron Wilson , David Rosenblatt
IPC分类号： B60J7/10 , C12N9/10 , C12Q1/68
CPC分类号： C12N9/1007
摘要： The invention features a novel gene encoding methionine synthase reductase. The invention also features a method for detecting an increased likelihood of hyperhomocysteinemia and, in turn, an increased or decreased likelihood of neural tube defects, cardiovascular disease, Down's Syndrome or cancer. The invention also features therapeutic methods for treating and/or reducing the risk of cardiovascular disease, Down's Syndrome, cancer, or neural tube defects. Also provided are the sequences of the human methionine synthase reductase gene and protein and compounds and kits for performing the methods of the invention.
摘要翻译：本发明的特征在于一种编码甲硫氨酸合成酶还原酶的新基因。本发明还特征在于一种用于检测高半胱氨酸血症的可能性增加的方法，反过来，增加或减少了神经管缺陷，心血管疾病，唐氏综合征或癌症的可能性。本发明还具有用于治疗和/或降低心血管疾病唐氏综合征，癌症或神经管缺陷风险的治疗方法。还提供了人甲硫氨酸合酶还原酶基因和蛋白质的序列，以及用于实施本发明方法的化合物和试剂盒。

4. 发明申请

US20120056389A1 VEHICLE SUSPENSION AND PNEUMATIC SYSTEMS 有权
标题翻译：车辆悬挂和气动系统
公开(公告)号：US20120056389A1
公开(公告)日：2012-03-08
申请号：US13320841
申请日：2010-05-28
申请人： Daniel Leclerc , Christian De Grammont
发明人： Daniel Leclerc , Christian De Grammont
IPC分类号： B60G17/052
CPC分类号： B60G17/0155 , B60G11/27 , B60G11/58 , B60G17/0526 , B60G17/056 , B60G2200/132 , B60G2200/144 , B60G2202/12 , B60G2202/152 , B60G2204/124 , B60G2204/126 , B60G2204/143 , B60G2204/18 , B60G2204/20 , B60G2206/0116 , B60G2206/60 , B60G2300/07 , B60G2300/124 , B60G2400/51222 , B60G2500/2012 , B60G2500/2021 , B60G2500/203 , B60G2500/205 , B60G2500/302 , B60G2600/042 , B60G2600/07 , B60G2600/18 , B60G2600/20 , B60G2600/68 , B60G2800/012 , B60G2800/014 , B60G2800/9122 , B60G2800/914 , B62K5/01 , B62K5/027 , B62K2005/001
摘要： A vehicle has a frame, at least one front wheel connected to the frame, at least one front suspension assembly connecting the at least one front wheel to the frame, at least one rear wheel connected to the frame, and at least one rear suspension assembly connecting the at least one rear wheel to the frame. At least one of the at least one front and at least one rear suspension assemblies includes an air spring. A seat is connected to the frame. An engine is connected to the frame and is operatively connected to at least one of the wheels. An air compressor is connected to the frame and fluidly communicates with the at least one air spring for supplying air to the at least one air spring. A control unit is electrically connected to the air compressor for controlling an operation of the air compressor.
摘要翻译：车辆具有框架，连接到框架的至少一个前轮，连接至少一个前轮到框架的至少一个前悬架组件，连接到框架的至少一个后轮，以及至少一个后悬架组件将所述至少一个后轮连接到所述框架。所述至少一个前悬挂组件和至少一个后悬架组件中的至少一个包括空气弹簧。座椅连接到框架。发动机连接到框架并且可操作地连接到至少一个车轮。空气压缩机连接到框架并与至少一个空气弹簧流体连通，用于向至少一个空气弹簧供应空气。控制单元电连接到空气压缩机以控制空气压缩机的操作。

5. 发明授权

US06285326B1 Patch antenna 失效
标题翻译：补片天线
公开(公告)号：US06285326B1
公开(公告)日：2001-09-04
申请号：US09581143
申请日：2000-06-09
申请人： Frédéric Diximus , Daniel Leclerc
发明人： Frédéric Diximus , Daniel Leclerc
IPC分类号： H01Q138
CPC分类号： H01Q1/38 , H01Q1/40 , H01Q9/0407 , H01Q9/0421
摘要： The invention relates to a microstrip antenna for transmitting and receiving waves of wave length &lgr;. It comprises a first insulating plate and a first metallization effected on a face of said plate in order to form a ground plane; a second insulating plate and at least one second metallization effected on a face of said second plate and presenting dimensions smaller than those of the first metallization; at least one feedline connected to said first and second metallization; and spacer means fastened with the two plates in order to maintain the two plates in a predetermined relative position so that the two metallizations face each other and the second metallization is opposite the first.
摘要翻译：本发明涉及一种用于发送和接收波长羔羊波的微带天线。它包括第一绝缘板和在所述板的表面上实现的第一金属化，以形成接地平面; 第二绝缘板和在所述第二板的表面上实现的至少一个第二金属化，并且具有小于所述第一金属化的尺寸的尺寸; 连接到所述第一和第二金属化的至少一个馈线; 以及用两个板固定的间隔件，以便将两个板保持在预定的相对位置，使得两个金属化物彼此面对，并且第二金属化与第一金属化相反。

6. 发明授权

US06947006B2 Colinear antenna of the alternating coaxial type 失效
标题翻译：共轴天线的交替同轴型
公开(公告)号：US06947006B2
公开(公告)日：2005-09-20
申请号：US10734113
申请日：2003-12-15
申请人： Frédéric Diximus , David Oliveira , Daniel Leclerc
发明人： Frédéric Diximus , David Oliveira , Daniel Leclerc
IPC分类号： H01Q11/16 , H01Q21/10 , H01Q1/16
CPC分类号： H01Q21/10
摘要： The invention relates to an antenna of colinear type. It comprises a radiating portion comprising: three substantially rectilinear conductive wire elements that are mutually parallel, comprising a central conductor and two lateral conductors; and 2N radiating zones constituted by alternating first radiating zones and second radiating zones: each first radiating zone further comprising a cylindrical conductive element whose axis coincides with said central wire element and which is electrically connected to both of said lateral wire elements; and each second radiating zone further comprises two cylindrical conductive elements whose axes coincide substantially respectively with the lateral wire elements, said cylindrical elements being electrically connected to said central wire element.
摘要翻译：本发明涉及一种共线型天线。它包括辐射部分，包括：相互平行的三个基本上直线的导线元件，包括中心导体和两个横向导体; 以及由交替的第一辐射区域和第二辐射区域构成的2 N个辐射区域：每个第一辐射区域还包括圆柱形导电元件，该圆柱形导电元件的轴与所述中心线元件重合并且与两个所述侧线元件电连接; 并且每个第二辐射区域还包括两个圆柱形导电元件，其轴线基本上分别与横向线元件重合，所述圆柱形元件电连接到所述中心线元件。

7. 发明授权

US06903690B2 Internal antenna of small volume 失效
标题翻译：内部天线体积小
公开(公告)号：US06903690B2
公开(公告)日：2005-06-07
申请号：US10713048
申请日：2003-11-17
申请人： Daniel Leclerc , Ayoub Annabi , Frédédric Diximus
发明人： Daniel Leclerc , Ayoub Annabi , Frédédric Diximus
IPC分类号： H01Q1/24 , H01Q5/00 , H01Q5/371 , H01Q9/04 , H01Q1/38
CPC分类号： H01Q1/243 , H01Q5/371 , H01Q9/0421
摘要： An internal antenna of small volume comprising: a conductive ground plane; a first conductive surface placed in an antenna plane substantially parallel to the ground plane and partially surrounding a portion of the antenna plane, and presenting first and second ends; a second conductive surface forming a main radiating assembly disposed essentially in said portion of the antenna plane, said two conductive surfaces not being connected together by any conductive electrical connection; an antenna conductor connected to said second conductive surface; first electrical connection means for connecting a first end of the first conductive surface to a first zone of the ground plane; and second electrical connection means for connecting said first surface at least in the vicinity of the second end of the first conductive surface to a second zone of the ground plane that is distinct from the first zone; the assembly constituted by said first conductive surface, the portion of the ground plane electrically interconnecting the first and second zones, and the two connection means presenting an opening.
摘要翻译：一种体积小的内部天线，包括：导电接地平面; 第一导电表面，其放置在基本上平行于接地平面并且部分地围绕天线平面的一部分的天线平面中，并且呈现第一端和第二端; 形成基本上位于所述天线平面的所述部分中的主辐射组件的第二导电表面，所述两个导电表面不通过任何导电电连接连接在一起; 连接到所述第二导电表面的天线导体; 第一电连接装置，用于将第一导电表面的第一端连接到接地平面的第一区; 以及第二电连接装置，用于至少在第一导电表面的第二端附近将所述第一表面连接到与第一区不同的接地平面的第二区; 所述组件由所述第一导电表面构成，所述接地平面的部分电连接所述第一和第二区域，所述两个连接装置具有开口。

8. 发明授权

US06326919B1 Patch antenna 失效
标题翻译：补片天线
公开(公告)号：US06326919B1
公开(公告)日：2001-12-04
申请号：US09446901
申请日：2000-01-03
申请人： Frédéric Diximus , Daniel Leclerc , Roland Vincent
发明人： Frédéric Diximus , Daniel Leclerc , Roland Vincent
IPC分类号： H01Q136
CPC分类号： H01Q9/0471 , H01Q1/243 , H01Q1/245 , H01Q5/357 , H01Q9/0407 , H01Q9/0421 , H01Q9/0442 , H01Q9/045
摘要： The invention relates to an internal antenna element of the patch type for a portable device. The element comprises a body of dielectric material, a conductive plate covering the top face of the dielectric, and a conductive strip covering one of the side faces of the dielectric, the strip being electrically connected along its top edge to one of the edges of said plate and being provided with electrical connection means for connecting said conductive strip to a ground plane that is to be placed against the bottom face of the dielectric body, the other three side faces having no metallization, means passing through the dielectric body for electrically connecting the hot point of an antenna conductor to said plate, and capacitor-forming means for providing capacitance between the plate and the ground plane when the antenna element is mounted on the ground plane, and located close to the side face of the dielectric body that is remote from its side face covered by said conductive strip.
摘要翻译：本发明涉及用于便携式设备的贴片类型的内部天线元件。元件包括介电材料体，覆盖电介质的顶面的导电板和覆盖电介质的一个侧面的导电条，该带沿其顶部边缘电连接到所述电介质的边缘之一并且设置有用于将所述导电条连接到抵靠电介质体的底面的接地平面的电连接装置，其他三个侧面没有金属化，穿过电介质体的装置用于电连接天线导体到所述板的热点，以及电容器形成装置，用于当天线元件安装在接地平面上时，在板和接地平面之间提供电容，并且位于靠近远离电介质的侧面从其由所述导电带覆盖的侧面。

9. 发明授权

US06588537B2 Gear shift assembly for straddle-type vehicle 失效
公开(公告)号：US06588537B2
公开(公告)日：2003-07-08
申请号：US09891866
申请日：2001-06-26
申请人： Roger Rioux , Claude Gagnon , Norbert Korenjak , Daniel Leclerc , Ghislain Caron , Mihai Rasidescu
发明人： Roger Rioux , Claude Gagnon , Norbert Korenjak , Daniel Leclerc , Ghislain Caron , Mihai Rasidescu
IPC分类号： B60K2600
CPC分类号： B60K23/02 , B60W10/02 , B60W10/11 , B60W30/19 , B60W2300/185 , B60W2540/16 , B60W2710/1005 , B60Y2200/124 , F16H63/46 , Y10S180/908
摘要： A system reduces the amount of work exerted by an ATV operator to change transmission gears. The system includes a foot lever assembly with a mechanical portion, such as a mechanical linkage, attached to an automated portion, such as an electrical switch. When the ATV operator applies a predetermined amount of force to the foot lever assembly, a clutch assembly and a gear box are actuated in a single motion, assisted by the automated portion of the foot lever assembly. Thus, the operator is able to exert less work in order to change the gears.

10. 发明授权

US4811755A Process for controlling the flow of a gas in a valve and flow generator employing said process 失效
标题翻译：用于控制采用所述方法的阀门和流量发生器中的气体流动的方法
公开(公告)号：US4811755A
公开(公告)日：1989-03-14
申请号：US131578
申请日：1987-12-11
申请人： Guy Bourdon , Dominique Lampin , Daniel Leclerc
发明人： Guy Bourdon , Dominique Lampin , Daniel Leclerc
IPC分类号： F16K31/04 , G05D7/06
CPC分类号： G05D7/0635 , Y10T137/7759 , Y10T137/7761 , Y10T137/86389
摘要： The valve comprises a movable closure member and a seat in which the closure member is displaced relative to the seat for varying the gas flow through the valve. According to the invention, the process comprises causing the displacement of the movable closure member by means of a step-by-step motor as a function of the variation of the flow produced by each step according to the geometry of the valve, the type of flow employed and the pressure of the gas on the upstream and/or downstream side of the valve, and then producing a corresponding control signal for displacing in the desired direction the motor through the number of steps corresponding to the calculated flow, the displacement of the motor causing the correlative displacement of the movable closure member.
摘要翻译：阀包括可移动的关闭构件和座，在该座中闭合构件相对于座移动以改变通过该阀的气流。根据本发明，该方法包括通过逐步电动机使可动闭合件的移动作为根据阀的几何形状的每个步骤产生的流动的变化的函数，使用的流量和气体在阀的上游侧和/或下游侧的压力，然后产生相应的控制信号，以通过与计算出的流量对应的步数在期望方向上移动电动机，电动机引起可移动关闭构件的相关位移。

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