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    • 1. 发明授权
    • Methods and devices for image-guided manipulation or sensing or anatomic structures
    • 用于图像引导操作或感测解剖结构的方法和装置
    • US08172757B2
    • 2012-05-08
    • US12213386
    • 2008-06-18
    • Ronen JaffeBradley H. StraussBrian K. Courtney
    • Ronen JaffeBradley H. StraussBrian K. Courtney
    • A61B8/12
    • A61B8/4461A61B5/0066A61B5/0084A61B5/0086A61B8/0833A61B8/0883A61B8/12A61B8/445A61B8/483A61B18/14A61B18/18
    • Forward-looking ultrasound transducers are positioned at the tip of a transseptal catheter to facilitate transseptal puncture and interventions within the left atrium, pulmonary veins and mitral valve. Catheter devices and systems are guided by forward-looking ultrasound or optical coherence tomography imaging for penetrating from one location within a mammalian patient's body to another location, and/or performing diagnostic or therapeutic interventions. A penetrator, diagnostic, or interventional device (eg. probe, biopsy apparatus, electrode, needle) is positioned at the catheter tip and is advanceable from the catheter to a target location outside of the lumen in which the catheter is positioned. The imaging probe uses forward-looking ultrasound or optical coherence tomography that allows one to locate both the target and the medical device. The operator may then adjust the position and/or rotational orientation of the catheter such that when the medical device is subsequently advanced it will either enter or be deployed at the target location.
    • 前瞻性超声换能器定位在经血管导管的尖端,以促进经腔穿刺和左心房,肺静脉和二尖瓣内的干预。 导管装置和系统由前瞻性超声或光学相干断层摄影成像引导,用于从哺乳动物患者体内的一个位置穿透到另一个位置,和/或执行诊断或治疗干预。 穿透器,诊断或介入装置(例如探针,活检装置,电极,针)定位在导管尖端处,并且可从导管前进到导管定位在其内的外部的目标位置。 成像探针使用前瞻性超声或光学相干断层扫描,其允许定位靶和医疗装置。 然后,操作者可以调整导管的位置和/或旋转取向,使得当医疗装置随后前进时,它将进入或部署在目标位置。
    • 2. 发明申请
    • Methods and devices for image-guided manipulation or sensing or anatomic structures
    • 用于图像引导操作或感测解剖结构的方法和装置
    • US20090088648A1
    • 2009-04-02
    • US12213386
    • 2008-06-18
    • Ronen JaffeBradley H. StraussBrian K. Courtney
    • Ronen JaffeBradley H. StraussBrian K. Courtney
    • A61B8/14
    • A61B8/4461A61B5/0066A61B5/0084A61B5/0086A61B8/0833A61B8/0883A61B8/12A61B8/445A61B8/483A61B18/14A61B18/18
    • Forward-looking ultrasound transducers are positioned at the tip of a transseptal catheter to facilitate transseptal puncture and interventions within the left atrium, pulmonary veins and mitral valve. Catheter devices and systems are guided by forward-looking ultrasound or optical coherence tomography imaging for penetrating from one location within a mammalian patient's body to another location, and/or performing diagnostic or therapeutic interventions. A penetrator, diagnostic, or interventional device (eg. probe, biopsy apparatus, electrode, needle) is positioned at the catheter tip and is advanceable from the catheter to a target location outside of the lumen in which the catheter is positioned. The imaging probe uses forward-looking ultrasound or optical coherence tomography that allows one to locate both the target and the medical device. The operator may then adjust the position and/or rotational orientation of the catheter such that when the medical device is subsequently advanced it will either enter or be deployed at the target location.
    • 前瞻性超声换能器定位在经血管导管的尖端,以促进经腔穿刺和左心房,肺静脉和二尖瓣内的干预。 导管装置和系统由前瞻性超声或光学相干断层摄影成像引导,用于从哺乳动物患者体内的一个位置穿透到另一个位置,和/或执行诊断或治疗干预。 穿透器,诊断或介入装置(例如探针,活检装置,电极,针)定位在导管尖端处,并且可从导管前进到导管定位在其内的外部的目标位置。 成像探针使用前瞻性超声或光学相干断层扫描,其允许定位靶和医疗装置。 然后,操作者可以调整导管的位置和/或旋转取向,使得当医疗装置随后前进时,它将进入或部署在目标位置。
    • 5. 发明授权
    • Fluid exchange system for controlled and localized irrigation and aspiration
    • 用于控制和局部灌溉和抽吸的流体交换系统
    • US06878128B2
    • 2005-04-12
    • US10819409
    • 2004-04-06
    • John M. MacMahonThomas G. GoffBrian K. Courtney
    • John M. MacMahonThomas G. GoffBrian K. Courtney
    • A61B17/22A61B17/00A61M1/00A61M25/00A61M5/178A61M3/00A61M5/00
    • A61M1/0058A61M1/0009A61M1/0064A61M1/0068
    • The control of fluid introduction into and out of body conduits such as vessels, is of great concern in medicine. As the development of more particular treatments to vessels and organs continues it is apparent that controlled introduction and removal of fluids is necessary. Fluid delivery and removal from such sites, usually referred to as irrigation and aspiration, using fluid exchange devices that control also need to be considerate of potential volume and/or pressure in the vessel or organ are described together with catheter and lumen configurations to achieve the fluid exchange. The devices include several electrically or mechanically controlled embodiments and produce both controlled and localized flow with defined volume exchange ratios for fluid management. The applications in medicine include diagnostic, therapeutic, imaging, and uses for the introduction or removal of concentrations of emboli within body cavities.
    • 液体导入和流出体液导管如血管的控制在医学上是非常关注的。 随着对血管和器官的更特殊的治疗的发展继续,显然需要控制引入和去除流体。 与导管和管腔配置一起描述使用控制的流体交换装置(通常称为灌注和抽吸)的流体输送和移除也需要考虑容器或器官中的潜在体积和/或压力,以实现 流体交换。 这些装置包括几个电气或机械控制的实施例,并产生具有限定的用于流体管理的体积交换比的受控和局部流。 药物中的应用包括用于引入或去除体腔内栓塞浓度的诊断,治疗,成像和用途。
    • 9. 发明授权
    • Fluid exchange system for controlled and localized irrigation and aspiration
    • 用于控制和局部灌溉和抽吸的流体交换系统
    • US07530976B2
    • 2009-05-12
    • US10903521
    • 2004-07-30
    • John M. MacMahonThomas G. GoffBrian K. Courtney
    • John M. MacMahonThomas G. GoffBrian K. Courtney
    • A61M5/178A61M31/00
    • A61M1/0058A61M1/0009A61M1/0064A61M1/0068
    • The control of fluid introduction into and out of body conduits such as vessels, is of great concern in medicine. As the development of more particular treatments to vessels and organs continues it is apparent that controlled introduction and removal of fluids is necessary. Fluid delivery and removal from such sites, usually referred to as irrigation and aspiration, using fluid exchange devices that control also need to be considerate of potential volume and/or pressure in the vessel or organ are described together with catheter and lumen configurations to achieve the fluid exchange. The devices include several electrically or mechanically controlled embodiments and produce both controlled and localized flow with defined volume exchange ratios for fluid management. The applications in medicine include diagnostic, therapeutic, imaging, and uses for the introduction or removal of concentrations of emboli within body cavities.
    • 液体导入和流出体液导管如血管的控制在医学上是非常关注的。 随着对血管和器官的更特殊的治疗的发展继续,显然需要控制引入和去除流体。 与导管和管腔配置一起描述使用控制的流体交换装置(通常称为灌注和抽吸)的流体输送和移除也需要考虑容器或器官中的潜在体积和/或压力,以实现 流体交换。 这些装置包括几个电气或机械控制的实施例,并产生具有限定的用于流体管理的体积交换比的受控和局部流。 药物中的应用包括用于引入或去除体腔内栓塞浓度的诊断,治疗,成像和用途。
    • 10. 发明授权
    • Embolization protection system for vascular procedures
    • 血管手术栓塞保护系统
    • US07108677B2
    • 2006-09-19
    • US09872068
    • 2001-05-31
    • Brian K. CourtneyJohn M. MacMahonThomas G. Goff
    • Brian K. CourtneyJohn M. MacMahonThomas G. Goff
    • A61M29/00
    • A61B17/22A61B17/22031A61B2017/22067A61B2017/22082A61B2017/22084A61F2/013A61F2002/018A61F2230/0006A61F2230/008
    • Apparatus and methods are described for effective removal of emboli or harmful fluids during vascular procedures, such as angiography, balloon angioplasty, stent deployment, laser angioplasty, atherectomy, intravascular ultrasonography and other therapeutic and diagnostic procedures. A catheter with an occluder mounted at its distal end creates an occlusion proximal to the lesion. The catheter provides a pathway for introducing a treatment catheter. Prior to, during or subsequent to the procedure, suction is activated to establish retrograde flow to remove emboli from the site. Additionally, a thin catheter with a distal fluid ejection nozzle maybe introduced distal to the treatment site to rinse emboli from the treatment site. The suction flow and/or ejected fluid flow may be varied in a pulsatile manner to simulate regular blood flow and/or perturb settled emboli into being captured that may otherwise not be collected. The method establishes a protective environment before any devices enter the site to be treated.
    • 描述了用于在血管手术(例如血管造影术,球囊血管成形术,支架展开,激光血管成形术,粥样斑块切除术,血管内超声检查和其他治疗和诊断程序)的血管手术中有效去除栓塞或有害流体的装置和方法。 具有安装在其远端的封堵器的导管在损伤附近产生闭塞。 导管提供用于引入治疗导管的途径。 在手术之前,期间或之后,吸力被激活以建立逆行流动以从现场除去栓塞。 此外,具有远端液体喷射嘴的薄导管可以在治疗部位的远端引入,以从治疗部位冲洗栓塞。 抽吸流体和/或排出的流体流动可以以脉动方式变化,以模拟正常血液流动和/或扰乱沉积的栓塞,从而可能不被收集。 该方法在任何设备进入待处理场所之前建立保护环境。