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1. 发明授权

US06697676B2 Medical electrical lead having an expandable electrode assembly 有权
标题翻译：具有可扩张电极组件的医用电线
公开(公告)号：US06697676B2
公开(公告)日：2004-02-24
申请号：US09836015
申请日：2001-04-17
申请人： Roger Dahl , Duane Zytkovicz , Stephen Sundquist , Thomas M. Soukup
发明人： Roger Dahl , Duane Zytkovicz , Stephen Sundquist , Thomas M. Soukup
IPC分类号： A61N104
CPC分类号： A61N1/056 , A61N2001/0578
摘要： An implantable device including an elastically compressible member coupled to a distal end of a lead and further coupled to at least one electrode. The compressible member is in a contracted state when the electrode is being delivered to an implant site. At the implant site, the compressible member is expanded to urge the electrode into contact with tissue. Compressible member further includes a keyed structure to engage a stiffening member such as a stylet. The stiffening member is used both to deliver the electrode to the implant site, and to rotate the compressible member, if necessary, so that the electrode contacts predetermined body tissue. According to one aspect of the invention, an introducer having an inner lumen with a diameter that is smaller than that of the compressible member may be used to disengage the stiffening member from the compressible member. In one embodiment, compressible member includes a conductor wound to form multiple turns that are aligned during electrode delivery, but which expand into a non-aligned configuration after deployment. In another embodiment, compressible member includes a spring clip that has a compressed profile during delivery, and an expanded profile after deployment.
摘要翻译：一种可植入装置，其包括耦合到引线的远端并进一步耦合到至少一个电极的弹性可压缩构件。当电极被输送到植入部位时，可压缩构件处于收缩状态。在植入位置，可压缩构件被膨胀以促使电极与组织接触。可压缩构件还包括用于接合诸如探针之类的加强构件的键合结构。加强构件用于将电极输送到植入位置，并且如果需要，可旋转可压缩构件，使得电极接触预定的身体组织。根据本发明的一个方面，可以使用具有直径小于可压缩构件直径的内腔的导引器来使加强构件从可压缩构件脱离。在一个实施例中，可压缩构件包括缠绕以形成多个匝的导体，其在电极传递期间对准，但在展开之后扩展成不对准构造。在另一个实施例中，可压缩构件包括弹簧夹，其在输送期间具有压缩轮廓，并且在展开之后具有扩展轮廓。

2. 发明授权

US06934589B2 System and method for placing endocardial leads 失效
标题翻译：放置心内膜导管的系统和方法
公开(公告)号：US06934589B2
公开(公告)日：2005-08-23
申请号：US09827108
申请日：2001-04-05
申请人： Stephen Sundquist , Arnold Thornton , Roger Dahl , Duane Zytkovicz , Kenneth C. Gardeski
发明人： Stephen Sundquist , Arnold Thornton , Roger Dahl , Duane Zytkovicz , Kenneth C. Gardeski
IPC分类号： A61N1/05 , A61N1/00
CPC分类号： A61N1/056 , A61N2001/0578 , A61N2001/0585
摘要： An improved system and method for deploying medical electrical leads is disclosed. The system includes a guiding device such as a guidewire used to navigate the vascular system of a body. The guiding device includes a fixation member that can be deployed to maintain the guiding device at a desired location within the vascular system. The fixation member may be an inflatable device such as a balloon, or alternatively, may be an expandable device constructed of flexible fibers that has both an expanded and a contracted state. The system may further include a coupling member located adjacent to the guiding device. The coupling member may be a rail extending distally from a proximal end of the guiding device to a point proximal the fixation member. In an alternative embodiment of the invention, the coupling member is a channel included in the body of the guiding device adapted to slidably engage an electrode assembly. The coupling member is adapted to allow the electrode assembly to be slid to the distal end of the coupling member and deployed at a predetermined implant site. In one embodiment of the invention, the coupling member is movable with respect to the guiding device. This allows the coupling member to be re-positioned to multiple implant sites to deploy more than one electrode while the fixation mechanism remains stationary within a patient's vascular system. According to yet another aspect of the invention, the guiding device includes a lumen to delivery fluoro visible medium.
摘要翻译：公开了用于部署医疗电引线的改进的系统和方法。该系统包括诸如用于导航身体的血管系统的导丝的引导装置。引导装置包括可以部署以将引导装置保持在血管系统内的期望位置的固定构件。固定构件可以是诸如气囊的可充气装置，或者可替代地，可以是由具有膨胀和收缩状态的柔性纤维构成的可扩张装置。该系统还可以包括邻近引导装置定位的联接构件。联接构件可以是从引导装置的近端向靠近固定构件的点向远侧延伸的轨道。在本发明的替代实施例中，联接构件是包括在引导装置的主体中的通道，其适于可滑动地接合电极组件。联接构件适于允许电极组件滑动到联接构件的远端并且在预定的植入位置展开。在本发明的一个实施例中，联接构件可相对于引导装置移动。这允许将联接构件重新定位到多个植入位置以展开多于一个电极，同时固定机构在患者的血管系统内保持静止。根据本发明的另一方面，引导装置包括用于输送氟可见介质的内腔。

3. 发明授权

US06249708B1 Fluted channel construction for a multi-conductor catheter lead 失效
标题翻译：用于多导体导管引线的沟槽结构
公开(公告)号：US06249708B1
公开(公告)日：2001-06-19
申请号：US08918321
申请日：1997-08-26
申请人： Randy S. Nelson , Roger Dahl , Duane Zytkovicz
发明人： Randy S. Nelson , Roger Dahl , Duane Zytkovicz
IPC分类号： A61N105
CPC分类号： A61N1/056
摘要： A multi-conductor fluted channel construction catheter lead is comprised of an elongated flexible tubular inner body member having a peripheral surface on which a plurality of longitudinally-oriented fluted channels are defined. A plurality of elongated conductors are provided with at least one conductor being disposed within one of the fluted channels and operably connected at a distal portion to an electrode and at a proximal portion to a connector. An outer insulative sheath member surrounds the inner body member and the conductors. A method of constructing a fluted channel catheter lead is also disclosed.
摘要翻译：多导体槽纹通道构造导管引线由细长的柔性管状内主体构件组成，其具有外周表面，多个纵向定向的沟槽通道限定在外周表面上。多个细长导体设置有至少一个导体，其布置在一个沟槽通道内，并且在远端部分可操作地连接到电极，并且在近端部分处连接到连接器。外绝缘护套构件围绕内体构件和导体。还公开了一种构建槽纹通道导管引线的方法。

4. 发明授权

US06697677B2 System and method for placing a medical electrical lead 有权
标题翻译：放置医用电线的系统和方法
公开(公告)号：US06697677B2
公开(公告)日：2004-02-24
申请号：US09826730
申请日：2001-04-05
申请人： Roger Dahl , Brad D. Pedersen , Duane Zytkovicz , Kenneth C. Gardeski
发明人： Roger Dahl , Brad D. Pedersen , Duane Zytkovicz , Kenneth C. Gardeski
IPC分类号： A61N105
CPC分类号： A61N1/056 , A61N2001/0578 , A61N2001/058 , A61N2001/0585
摘要： An improved system and method that is capable of delivering multiple electrode assemblies to predetermined implant sites within a body is disclosed. The system includes an elongated member such as an introducer sheath. The introducer includes an elongated channel along at least a distal end portion of the introducer. The elongated channel opens to the exterior surface of the introducer through an elongated slot. One or more electrode assemblies may be retained within the elongated channel such that the leads exit the introducer via the elongated slot. The elongated introducer further includes a lumen that is in fluid communication with channel through openings, or gaps. The electrode assemblies are loaded within the channel at predetermined positions with respect to the openings. A distal end of a stiffening member such as a stylet may then be advanced within the lumen and through a selected one of the openings to engage an electrode assembly. The distal end of the stylet, along with the electrode assembly, is pushed in a distal direction within the channel until the electrode assembly exits the channel at a predetermined implant site. The stylet is then de-coupled from the electrode assembly, and the distal end is again retracted into the lumen. The distal end of the stiffening member may be re-directed into a different opening to engage a second electrode assembly. After the introducer is repositioned at a second implant site, the second electrode assembly may be deployed in a manner similar to that discussed above. The process may be repeated to deploy an array of electrodes. According to one aspect of the invention, the stylet distal end is canted to extend from the lumen of the introducer into the channel.
摘要翻译：公开了能够将多个电极组件递送到体内预定植入部位的改进的系统和方法。该系统包括细长构件，例如导引器护套。导引器包括沿导引器的至少远端部分的细长通道。细长通道通过细长的槽向导引器的外表面开口。一个或多个电极组件可以保持在细长通道内，使得引线经由细长槽离开导引器。细长导引器还包括与通道通过开口或间隙流体连通的内腔。电极组件相对于开口在预定位置处装载在通道内。然后，诸如探针之类的加强构件的远端可以在内腔内并通过选定的一个开口进入以接合电极组件。探针的远端与电极组件一起沿通道内的远端方向推动，直到电极组件在预定的植入部位离开通道。然后将探针从电极组件脱耦合，并且远端再次缩回到内腔中。加强构件的远端可以被重新引导到不同的开口中以接合第二电极组件。在导引器在第二植入位置重新定位之后，第二电极组件可以以与上述相似的方式展开。可以重复该过程以展开电极阵列。根据本发明的一个方面，探针的远端倾斜以从导引器的内腔延伸到通道中。

5. 发明授权

US5782898A System for anchoring mid-lead electrode on an endocardial catheter lead 失效
标题翻译：用于在心内膜导管引线上固定中间引线电极的系统
公开(公告)号：US5782898A
公开(公告)日：1998-07-21
申请号：US729900
申请日：1996-10-15
申请人： Roger Dahl , Duane Zytkovicz
发明人： Roger Dahl , Duane Zytkovicz
IPC分类号： A61N1/05
CPC分类号： A61N1/057
摘要： A system for passively anchoring mid-lead electrodes on an endocardial catheter lead includes at least one fibrosis-anchoring opening positioned along the exterior surface of the catheter lead body proximal or distal to the mid-lead electrodes for passively securing the catheter lead against the interior wall of the heart. Within the fibrosis-anchoring openings a suitable material is provided for anchoring the catheter lead body to the heart wall by fibrosis. Preferably, the fibrosis-anchoring openings comprise at least a pair of openings positioned only partially around the exterior of the catheter lead body at locations both proximal and distal to the mid-lead electrodes, with the catheter lead body between the fibrosis-anchoring openings being pre-formed to bias the mid-lead electrodes against the heart wall.
摘要翻译：用于在心内膜导管引线上被动地固定中间引线电极的系统包括至少一个纤维化锚定开口，沿着导管引线体的外表面位于中间引线电极的近端或远端，用于被动地将导管引线固定在内部心脏的墙壁在纤维化锚定开口内，提供合适的材料用于通过纤维化将导管引线体锚固到心脏壁。优选地，纤维化锚定开口包括至少一对开口，该对开口仅位于导联引线体的外部位于中间引线电极的近端和远端的位置处，导线引线主体位于纤维化锚定开口之间预先形成以将中间引线电极偏压抵靠心壁。

6. 发明授权

US5213115A Inflation system for a balloon catheter 失效
标题翻译：气球导管系统
公开(公告)号：US5213115A
公开(公告)日：1993-05-25
申请号：US601431
申请日：1990-10-23
申请人： Duane Zytkovicz , Thomas J. McEvoy , Gregory G. Brucker
发明人： Duane Zytkovicz , Thomas J. McEvoy , Gregory G. Brucker
IPC分类号： A61M25/00 , A61F2/958 , A61M5/48
CPC分类号： A61M25/104 , A61M25/01 , A61M25/1018 , A61M5/488
摘要： An inflation system for pressurization and depressurization of a balloon catheter. The inflation system includes a syringe, including a syringe barrel, a plunger with expandable thread, a handle with cam, a syringe end cap, pressure gauge, flexible tubing, and connectors. The syringe is structured such that part of the syringe barrel has an internal thread which engages the expandable threads of the plunger. In the disengaged mode, the plunger slides freely within the syringe barrel allowing for rapid motion to purge, pressurize, or depressurize the inflation system. Once pressure reaches a predetermined level in the system, the cam on the handle causes the threads to automatically lock against the syringe barrel, and continued pressurization or depressurization is accomplished by the rotation of the plunger handle with respect to the syringe barrel. One advantage of the inflation system is that only one step is necessary for locking the syringe for controlled pressurization and depressurization.
摘要翻译：用于气囊导管加压和减压的充气系统。充气系统包括注射器，包括注射器筒，具有可扩展螺纹的柱塞，具有凸轮的手柄，注射器端盖，压力计，柔性管和连接器。注射器被构造成使得注射器筒的一部分具有接合柱塞的可膨胀螺纹的内螺纹。在分离模式中，柱塞在注射器筒内自由滑动，允许快速运动以吹扫，加压或减压充气系统。一旦压力在系统中达到预定水平，手柄上的凸轮就会导致螺纹自动锁定注射器筒，并且通过柱塞手柄相对于注射器筒的旋转来实现持续的加压或减压。膨胀系统的一个优点是只需要一个步骤来锁定注射器以进行受控的加压和减压。

7. 发明授权

US5056528A Pressure gauge: gelatinous filled bourdon tube 失效
标题翻译：压力表：凝胶填充的布尔登管
公开(公告)号：US5056528A
公开(公告)日：1991-10-15
申请号：US568085
申请日：1990-08-16
申请人： Duane Zytkovicz , Thomas J. McEvoy
发明人： Duane Zytkovicz , Thomas J. McEvoy
IPC分类号： G01L7/04
CPC分类号： G01L7/04
摘要： A pressure gauge including a bourdon tube where a substantial portion of the pressure gauge is filled with a silicone gel, gelatinous material, or any other suitable materials.
摘要翻译：包括布尔登管的压力表，其中大部分压力表填充有硅胶，凝胶状材料或任何其它合适的材料。

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