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1. 发明授权

US5876976A Method for reducing carryover contamination in an amplification procedure 失效
公开(公告)号：US5876976A
公开(公告)日：1999-03-02
申请号：US376762
申请日：1995-01-23
申请人： Rodney M. Richards , Theodore Jones , David L. Snitman , Gregory S. Brown
发明人： Rodney M. Richards , Theodore Jones , David L. Snitman , Gregory S. Brown
IPC分类号： C12N15/09 , C12N15/00 , C12Q1/68 , C12Q1/70 , C12P19/34
CPC分类号： C12Q1/6848 , C12Q1/6862 , C12Q1/703 , Y10S435/81
摘要： The present invention provides an efficient and economical method for reducing carryover contamination in an amplification procedure. The method of the present invention enables background caused by contaminant amplification product to be reduced or eliminated through the incorporation of at least one modification into the amplification product. The modified amplification product is readily distinguishable from the target sequence in a test sample. Prior to amplifying the target in a new test sample, the sample may be treated to selectively eliminate the contaminant amplification product so that it cannot be amplified in the new sample.

2. 发明授权

US5427929A Method for reducing carryover contamination in an amplification procedure 失效
标题翻译：在扩增过程中减少残留污染的方法
公开(公告)号：US5427929A
公开(公告)日：1995-06-27
申请号：US057192
申请日：1993-05-03
申请人： Rodney M. Richards , Theodore Jones , David L. Snitman , Gregory S. Brown
发明人： Rodney M. Richards , Theodore Jones , David L. Snitman , Gregory S. Brown
IPC分类号： C12N15/09 , C12N15/00 , C12Q1/68 , C12Q1/70 , C12P19/34
CPC分类号： C12Q1/6848 , C12Q1/6862 , C12Q1/703 , Y10S435/81
摘要： The present invention provides an efficient and economical method for reducing carryover contamination in an amplification procedure. The method of the present invention enables background caused by contaminant amplification product to be reduced or eliminated through the incorporation of at least one modification into the amplification product. The modified amplification product is readily distinguishable from the target sequence in a test sample. Prior to amplifying the target in a new test sample, the sample may be treated to selectively cleave the contaminant amplification product so that it cannot be amplified in the new sample.
摘要翻译：本发明提供了一种在放大过程中减少携带污染的有效且经济的方法。通过将至少一种修饰引入扩增产物，本发明的方法能够减少或消除由污染物扩增产物引起的背景。修饰的扩增产物可以容易地与测试样品中的靶序列区分开。在放大新的测试样品中的靶之前，可以处理样品以选择性地切割污染物扩增产物，使得其不能在新样品中扩增。

3. 发明授权

US6037152A Method for reducing carryover contamination in an amplification procedure 失效
标题翻译：在扩增过程中减少残留污染的方法
公开(公告)号：US6037152A
公开(公告)日：2000-03-14
申请号：US376763
申请日：1995-01-23
申请人： Rodney M. Richards , Theodore Jones , Gregory S. Brown
发明人： Rodney M. Richards , Theodore Jones , Gregory S. Brown
IPC分类号： C12N15/09 , C12N15/00 , C12Q1/68 , C12Q1/70 , C12P19/34 , C12N9/14 , C12N9/24
CPC分类号： C12Q1/6848 , C12Q1/6862 , C12Q1/703 , Y10S435/81
摘要： The present invention provides an efficient and economical method for reducing carryover contamination in an amplification procedure. The method of the present invention enables background caused by contaminant amplification product to be reduced or eliminated through the incorporation of at least one modification into the amplification product. The modified amplification product is readily distinguishable from the target sequence in a test sample. Prior to amplifying the target in a new test sample, the sample may be treated to selectively eliminate the contaminant amplification product so that it cannot be amplified in the new sample.
摘要翻译：本发明提供了一种在放大过程中减少携带污染的有效且经济的方法。通过将至少一种修饰引入扩增产物，本发明的方法能够降低或消除由污染物扩增产物引起的背景。修饰的扩增产物可以容易地与测试样品中的靶序列区分开。在放大新的测试样品中的靶之前，可以处理样品以选择性地消除污染物扩增产物，使得其不能在新样品中扩增。

4. 发明授权

US5650302A Method for reducing carryover contamination in an amplification procedure 失效
标题翻译：在扩增过程中减少残留污染的方法
公开(公告)号：US5650302A
公开(公告)日：1997-07-22
申请号：US469085
申请日：1995-06-05
申请人： Rodney M. Richards , Theodore Jones , Gregory S. Brown
发明人： Rodney M. Richards , Theodore Jones , Gregory S. Brown
IPC分类号： C12Q1/68 , C12Q1/70 , C12P19/34
CPC分类号： C12Q1/6848
摘要： The present invention provides an efficient and economical method for reducing carryover contamination in an amplification procedure. The method of the present invention enables background caused by contaminant amplification product to be reduced or eliminated through the incorporation of at least one modification into the amplification product. The modified amplification product is readily distinguishable from the target sequence in a test sample. Prior to amplifying the target in a new test sample, the sample may be treated to selectively eliminate the contaminant amplification product so that it cannot be amplified in the new sample.
摘要翻译：本发明提供了一种在放大过程中减少携带污染的有效且经济的方法。通过将至少一种修饰引入扩增产物，本发明的方法能够降低或消除由污染物扩增产物引起的背景。修饰的扩增产物可以容易地与测试样品中的靶序列区分开。在放大新的测试样品中的靶之前，可以处理样品以选择性地消除污染物扩增产物，使得其不能在新样品中扩增。

5. 发明授权

US07285401B1 Method and reagents for detecting nucleic acid sequences 失效
标题翻译：用于检测核酸序列的方法和试剂
公开(公告)号：US07285401B1
公开(公告)日：2007-10-23
申请号：US08480005
申请日：1995-06-07
申请人： Theodore Jones , Rodney M. Richards
发明人： Theodore Jones , Rodney M. Richards
IPC分类号： C12Q1/00
CPC分类号： C12Q1/6844
摘要： The present invention is directed to a method for detecting an amplification product. Amplification is accomplished through the use of a plurality of detection probes. The present invention is also directed to a method for detecting a target nucleic acid sequence by contacting a test sample with an excess of at least three pairs of nucleic acid amplification probes.
摘要翻译：本发明涉及一种检测扩增产物的方法。通过使用多个检测探针实现扩增。本发明还涉及通过使测试样品与过量的至少三对核酸扩增探针接触来检测靶核酸序列的方法。

6. 发明申请

US20070127912A1 Surveillance camera gimbal mechanism 有权
标题翻译：监视摄像机云台机制
公开(公告)号：US20070127912A1
公开(公告)日：2007-06-07
申请号：US11295013
申请日：2005-12-06
申请人： Theodore Jones , Kathleen Arnold
发明人： Theodore Jones , Kathleen Arnold
IPC分类号： G03B17/00
CPC分类号： F16M11/2014 , F16M11/10 , G02B7/005 , G08B13/1963
摘要： A surveillance camera gimbal mechanism. The mechanism utilizes a rotationally adjustable disk and support arrangement to afford smoothly adjustable, fastener-free, and stable diagonal adjustment that also provides axial compliance. The diagonal adjustment mechanism is integrated with a pan and tilt gimbal mechanism to allow smooth and stable single-point manual fixation of pan and tilt positions without creating depressions in the mating parts which make readjustment difficult.
摘要翻译：监视摄像机万向节机制。该机构采用可旋转调整的盘片和支撑装置，以提供平滑可调，无紧固件和稳定的对角线调整，同时提供轴向顺应性。对角调整机构与平移和俯仰万向架机构相结合，可以平稳稳定的单点手动固定平移和倾斜位置，而不会在配合部分产生凹陷，从而使调整变得困难。

7. 发明申请

US20060044406A1 Rotatable camera system including infrared communications links 失效
公开(公告)号：US20060044406A1
公开(公告)日：2006-03-02
申请号：US10926799
申请日：2004-08-26
申请人： Lonnel Swarr , Theodore Jones
发明人： Lonnel Swarr , Theodore Jones
IPC分类号： H04N5/232
CPC分类号： H04N5/23238 , H04N5/2251 , H04N5/23203
摘要： A camera system includes a camera assembly and a base. A mounting assembly rotatably mounts the camera assembly on the base. The camera assembly is rotatable through a range of 360 degrees relative to the base about an axis of rotation. The mounting assembly provides electrical communication between the camera assembly and the base. A first emitter and a first detector wirelessly communicate signals therebetween. One of the first emitter and the first detector is mounted on the camera assembly and the other of the first emitter and the first detector is mounted on the base. A second emitter and a second detector wirelessly communicate signals therebetween. One of the second emitter and the second detector is mounted on the camera assembly and the other of the second emitter and the second detector is mounted on the base.

8. 发明申请

US20060096802A1 Remote underwater laser acoustic source 有权
标题翻译：远程水下激光声源
公开(公告)号：US20060096802A1
公开(公告)日：2006-05-11
申请号：US11268400
申请日：2005-11-02
申请人： Theodore Jones , Antonio Ting , Phillip Sprangle , Leonard Bibee , Joseph Penano
发明人： Theodore Jones , Antonio Ting , Phillip Sprangle , Leonard Bibee , Joseph Penano
IPC分类号： G10K15/04
CPC分类号： G10K15/046
摘要： A method for generating an acoustic source in a liquid includes transmitting an optical pulse through the liquid so the optical pulse reaches ILIB through pulse compression and ionizes a liquid volume. The pulse compression is achieved through at least one of a) group velocity dispersion induced longitudinal compression of a frequency chirped optical pulse and b) transverse self focusing via a nonlinear optical Kerr effect. The acoustic source can be generated at a controllable remote location many meters from the optical source. The optical source can be a laser or other suitable optical device.
摘要翻译：用于在液体中产生声源的方法包括：通过液体传输光脉冲，使得光脉冲通过脉冲压缩达到I LIB，并离子化液体体积。脉冲压缩是通过a）组速度色散引起的频率啁啾光脉冲的纵向压缩和b）通过非线性光学克尔效应的横向自聚焦中的至少一个来实现的。声源可以在距离光源许多米的可控远程位置产生。光源可以是激光器或其他合适的光学器件。

9. 发明授权

US4699897A Biologically active peptides structurally related to regions within growth hormones 失效
标题翻译：生物活性肽结构上与生长激素内的区域有关
公开(公告)号：US4699897A
公开(公告)日：1987-10-13
申请号：US501024
申请日：1983-06-04
申请人： Theodore Jones , Christopher G. Rudman
发明人： Theodore Jones , Christopher G. Rudman
IPC分类号： C07K5/08 , A61K38/00 , A61K38/27 , A61K38/28 , A61P3/08 , A61P5/00 , C07K5/10 , C07K5/107 , C07K7/06 , C07K7/08 , C07K14/575 , C07K14/61 , A61K37/26
CPC分类号： C07K14/61 , C07K5/1016 , A61K38/00 , Y10S930/12
摘要： Disclosed are novel synthetic peptides having primary structural homology to a continuous sequence of amino acid residues of human growth hormone in a region spanning positions thirty-two to forty-six ("hGH.sub.32-46 ", or "deletion peptide"). In preferred forms, peptides of the invention comprehend: duplicate portions (i.e., sequence fragments) of hGH.sub.32-46 ; stereochemical analogs and fragment analogs of hGH.sub.32-46 including one or more amino acid residues in D-isomeric configuration; and, "interspecies" analogs and fragment analogs of hGH.sub.32-46 including one or more non-homologous amino acid residues duplicating variant residues present in corresponding positions in corresponding regions of heterologous species growth hormones. Peptides of the invention are administered to mammals contemporaneously with exogenous insulin to generate hypoglycemic effects greater than available through administration of insulin alone. A presently preferred heptapeptide has the sequence, NH.sub.2 -Glu-Glu-Ala-Tyr-Ile-Pro-Lys-COOH, and has insulin-potentiating activity greater than hGH.sub.32-46.
摘要翻译：公开了在跨越位置32至46位（“hGH32-46”或“缺失肽”）的区域中与人生长激素的氨基酸残基的连续序列具有初级结构同源性的新型合成肽。在优选形式中，本发明的肽包括hGH32-46的重复部分（即序列片段）; hGH32-46的立体化学类似物和片段类似物包括D-异构体构型中的一个或多个氨基酸残基; 以及hGH32-46的“种间”类似物和片段类似物，包括一个或多个重复存在于异源物种生长激素相应区域中相应位置的变体残基的非同源氨基酸残基。将本发明的肽与外源性胰岛素同时施用于哺乳动物，以产生比通过单独施用胰岛素可获得的降血糖作用更大的降血糖作用。目前优选的七肽具有序列NH2-Glu-Glu-Ala-Tyr-Ile-Pro-Lys-COOH，并且具有大于hGH32-46的胰岛素增强活性。

10. 发明申请

US20060024046A1 Compound dome window for a surveillance camera 有权
标题翻译：用于监控摄像机的复合穹顶窗
公开(公告)号：US20060024046A1
公开(公告)日：2006-02-02
申请号：US10967856
申请日：2004-10-18
申请人： Theodore Jones , Richard Wright
发明人： Theodore Jones , Richard Wright
IPC分类号： G03B17/00
CPC分类号： G08B13/19632 , G08B13/19619 , G08B13/1963
摘要： A surveillance camera assembly includes a dome window having a substantially cylindrical section with an inner surface and a first annular end. A substantially hemispherical section has a concave surface and a second annular end. The second annular end is joined to the first annular end of the substantially cylindrical section. The concave surface and the inner surface of the substantially cylindrical section conjointly define a cavity. Both the substantially cylindrical section and the substantially hemispherical section are substantially transparent when viewing outwardly from a position within the cavity. A surveillance camera is received in the cavity of the dome window and swivels relative to the dome window.
摘要翻译：监视摄像机组件包括具有大致圆柱形部分的圆顶窗口，其具有内表面和第一环形端。大致半球形部分具有凹面和第二环形端。第二环形端连接到大致圆柱形部分的第一环形端。基本圆柱形部分的凹面和内表面共同限定了空腔。当从空腔内的位置向外观察时，基本上圆柱形部分和基本上半球形部分都是基本透明的。监视摄像机被接收在穹顶窗的腔中并相对于穹顶窗转动。

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