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1. 发明授权

US07989042B2 Medical devices with highly flexible coated hypotube 有权
标题翻译：具有高柔性涂层海波管的医疗设备
公开(公告)号：US07989042B2
公开(公告)日：2011-08-02
申请号：US10996976
申请日：2004-11-24
申请人： Robert Z. Obara , Gregory E. Mirigian , Huey Quoc Chan , John E. Ortiz , Stephen Griffin
发明人： Robert Z. Obara , Gregory E. Mirigian , Huey Quoc Chan , John E. Ortiz , Stephen Griffin
IPC分类号： A61B5/00 , A61M25/00
CPC分类号： A61L29/14 , A61L29/085 , Y10T428/1321 , Y10T428/1352 , Y10T428/139 , Y10T428/2913
摘要： Hypotubes such as micromachined hypotubes can include one or more tie layers appropriate for subsequent application of a hydrophilic coating. In particular, a medical device may include a micromachined hypotube having a level of flexibility and a tie layer disposed over the hypotube such that the medical device has a level of flexibility at least substantially equivalent to the level of flexibility of the hypotube.
摘要翻译：诸如微加工的海波管之类的低管可以包括适于随后应用亲水涂层的一个或多个连接层。特别地，医疗装置可以包括具有柔性水平的微加工海波管和设置在海波管上方的连接层，使得医疗装置具有至少基本上等于海波管的柔性水平的柔性水平。

2. 发明授权

US5715827A Ultra miniature pressure sensor and guide wire using the same and method 失效
标题翻译：超微型压力传感器和导丝采用相同的方法
公开(公告)号：US5715827A
公开(公告)日：1998-02-10
申请号：US710062
申请日：1996-09-09
申请人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
发明人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
IPC分类号： A61B5/0215 , A61F2/958 , A61M25/00 , A61M25/09 , G01L9/00 , A61B5/00
CPC分类号： G01L19/141 , A61B5/0215 , A61B5/6851 , A61M25/09 , G01L19/0084 , G01L19/147 , G01L19/149 , G01L9/0054 , A61M2025/0002 , A61M2025/09008 , A61M2025/09083 , A61M25/10
摘要： A guidewire having pressure sensing capabilities for measuring the pressure of liquid in a vessel comprising a flexible elongate member and having proximal and distal extremities and having an outside diameter of 0.018" or less. The distal extremity of said flexible elongate member is adapted to be disposed in the liquid in said vessel. A housing is carried by the flexible elongate member and has a diameter substantially the same as the diameter of the flexible elongate member. The housing has a space therein with a pressure sensor mounted in the space in the housing. The pressure sensor has a diaphragm that is sensitive to changes of pressure in the liquid in the vessel. The diaphragm is rectangular in shape and is bordered by a rim surrounding the well. A backing plate is formed of an insulating material bonded to the crystal and serves to reinforce the rim of the crystal of semiconductor material. The backing plate has a cavity therein underlying the diaphragm and is in substantial registration with the diaphragm. The cavity serves to provide a pressure reference.
摘要翻译：一种具有用于测量容器中的液体压力的压力传感能力的导丝，包括柔性细长构件并且具有近端和远端，外径为0.018“或更小。所述柔性细长构件的远端适于设置在所述容器中的液体中。壳体由柔性细长构件承载并且具有与柔性细长构件的直径基本相同的直径。壳体具有安装在壳体的空间中的压力传感器的空间。压力传感器具有对容器中的液体中的压力变化敏感的隔膜。隔膜是矩形的形状，并且围绕着井的边缘。背板由结合到晶体上的绝缘材料形成，用于加强半导体材料晶体的边缘。背板在其下面具有腔室，并且与隔膜基本上对准。腔用于提供压力参考。

3. 发明授权

US06767327B1 Method of measuring blood pressure and velocity proximally and distally of a stenosis 有权
标题翻译：测量血压和速度近端和远端狭窄的方法
公开(公告)号：US06767327B1
公开(公告)日：2004-07-27
申请号：US09644111
申请日：2000-08-21
申请人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
发明人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
IPC分类号： A61B500
CPC分类号： G01L19/141 , A61B5/0215 , A61B5/6851 , A61B8/06 , A61B8/12 , A61M25/09 , A61M25/10 , A61M2025/0002 , A61M2025/09008 , A61M2025/09083 , G01L9/0054 , G01L19/0084 , G01L19/147 , G01L19/149
摘要： A method of measuring blood pressure and velocity proximally and distally of a stenosis in a vessel carrying blood includes the steps of providing a guide wire having both a pressure sensor and a velocity sensor disposed on a distal region of the guide wire, introducing the guide wire into the vessel, advancing the guide wire to position the pressure sensor and the velocity sensor proximally and distally of the stenosis, and measuring the blood pressure and velocity proximally and distally of the stenosis with the pressure sensor and the velocity sensor.
摘要翻译：一种在携带血液的容器中向近端和远端测量血压和速度的方法，包括提供具有设置在导丝的远侧区域上的压力传感器和速度传感器两者的导丝的步骤，将引导线进入容器，推进导丝以将压力传感器和速度传感器定位在近端和远端的狭窄处，并用压力传感器和速度传感器测量近端和远端狭窄的血压和速度。

4. 发明授权

US08419647B2 Ultra miniature pressure sensor 有权
标题翻译：超微型压力传感器
公开(公告)号：US08419647B2
公开(公告)日：2013-04-16
申请号：US13169174
申请日：2011-06-27
申请人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
发明人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
IPC分类号： A61B5/02
CPC分类号： G01L19/141 , A61B5/0215 , A61B5/6851 , A61B8/06 , A61B8/12 , A61M25/09 , A61M25/10 , A61M2025/0002 , A61M2025/09008 , A61M2025/09083 , G01L9/0054 , G01L19/0084 , G01L19/147 , G01L19/149
摘要： A method of measuring blood pressure and velocity proximally and distally of a stenosis in a vessel carrying blood includes the steps of providing a guide wire having both a pressure sensor and a velocity sensor disposed on a distal region of the guide wire, introducing the guide wire into the vessel, advancing the guide wire to position the pressure sensor and the velocity sensor proximally and distally of the stenosis, and measuring the blood pressure and velocity proximally and distally of the stenosis with the pressure sensor and the velocity sensor.
摘要翻译：一种在携带血液的容器中向近端和远端测量血压和速度的方法，包括提供具有设置在导丝的远侧区域上的压力传感器和速度传感器两者的导丝的步骤，将引导线进入容器，推进导丝以将压力传感器和速度传感器定位在近端和远端的狭窄处，并用压力传感器和速度传感器测量近端和远端狭窄的血压和速度。

5. 发明授权

US06976965B2 Ultra miniature pressure sensor 失效
标题翻译：超微型压力传感器
公开(公告)号：US06976965B2
公开(公告)日：2005-12-20
申请号：US10247043
申请日：2002-09-19
申请人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
发明人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
IPC分类号： A61B5/0215 , A61F2/958 , A61M25/00 , A61M25/09 , G01L9/00 , A61B5/00
CPC分类号： G01L19/141 , A61B5/0215 , A61B5/6851 , A61B8/06 , A61B8/12 , A61M25/09 , A61M25/10 , A61M2025/0002 , A61M2025/09008 , A61M2025/09083 , G01L9/0054 , G01L19/0084 , G01L19/147 , G01L19/149
摘要： A guide wire having pressure sensing capabilities for measuring the pressure of liquid in a vessel comprising a flexible elongate member and having proximal and distal extremities and having an outside diameter of 0.018″ or less. The distal extremity of said flexible elongate member is adapted to be disposed in the liquid in said vessel. A housing is carried by the flexible elongate member and has a diameter substantially the same as the diameter of the flexible elongate member. The housing has a space therein with a pressure sensor mounted in the space in the housing. The pressure sensor has a diaphragm that is sensitive to changes of pressure in the liquid in the vessel. The diaphragm is rectangular in shape and is bordered by a rim surrounding the well. A backing plate is formed of an insulating material bonded to the crystal and serves to reinforce the rim of the crystal of semiconductor material. The backing plate has a cavity therein underlying the diaphragm and is in substantial registration with the diaphragm. The cavity serves to provide a pressure reference.
摘要翻译：一种导丝，其具有用于测量容器中液体的压力的压力感测能力，该容器包括柔性细长构件并具有近端和远端，外径为0.018“或更小。所述柔性细长构件的远端适于设置在所述容器中的液体中。壳体由柔性细长构件承载并且具有与柔性细长构件的直径基本相同的直径。壳体具有安装在壳体的空间中的压力传感器的空间。压力传感器具有对容器中的液体中的压力变化敏感的隔膜。隔膜是矩形的形状，并且围绕着井的边缘。背板由结合到晶体上的绝缘材料形成，用于加强半导体材料晶体的边缘。背板在其下面具有腔室，并且与隔膜基本上对准。腔用于提供压力参考。

6. 发明授权

US6106476A Ultra miniature pressure sensor and guide wire using the same and method 失效
标题翻译：超微型压力传感器和导丝采用相同的方法
公开(公告)号：US6106476A
公开(公告)日：2000-08-22
申请号：US912879
申请日：1997-08-15
申请人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
发明人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
IPC分类号： A61B5/0215 , A61F2/958 , A61M25/00 , A61M25/09 , G01L9/00 , A61B5/00
CPC分类号： G01L19/141 , A61B5/0215 , A61B5/6851 , A61M25/09 , G01L19/0084 , G01L19/147 , G01L19/149 , G01L9/0054 , A61M2025/0002 , A61M2025/09008 , A61M2025/09083 , A61M25/10
摘要： A guide wire having pressure sensing capabilities for measuring the pressure of liquid in a vessel comprising a flexible elongate member and having proximal and distal extremities and having an outside diameter of 0.018" or less. The distal extremity of said flexible elongate member is adapted to be disposed in the liquid in said vessel. A housing is carried by the flexible elongate member and has a diameter substantially the same as the diameter of the flexible elongate member. The housing has a space therein with a pressure sensor mounted in the space in the housing. The pressure sensor has a diaphragm that is sensitive to changes of pressure in the liquid in the vessel. The diaphragm is rectangular in shape and is bordered by a rim surrounding the well. A backing plate is formed of an insulating material bonded to the crystal and serves to reinforce the rim of the crystal of semiconductor material. The backing plate has a cavity therein underlying the diaphragm and is in substantial registration with the diaphragm. The cavity serves to provide a pressure reference.
摘要翻译：一种导丝，其具有用于测量容器中液体的压力的压力感测能力，该容器包括柔性细长构件并具有近端和远端，外径为0.018“或更小。所述柔性细长构件的远端适于设置在所述容器中的液体中。壳体由柔性细长构件承载并且具有与柔性细长构件的直径基本相同的直径。壳体具有安装在壳体的空间中的压力传感器的空间。压力传感器具有对容器中的液体中的压力变化敏感的隔膜。隔膜是矩形的形状，并且围绕着井的边缘。背板由结合到晶体上的绝缘材料形成，用于加强半导体材料晶体的边缘。背板在其下面具有腔室，并且与隔膜基本上对准。腔用于提供压力参考。

7. 发明申请

US20110251497A1 Ultra Miniature Pressure Sensor 有权
标题翻译：超微型压力传感器
公开(公告)号：US20110251497A1
公开(公告)日：2011-10-13
申请号：US13169174
申请日：2011-06-27
申请人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
发明人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
IPC分类号： A61B5/0215
CPC分类号： G01L19/141 , A61B5/0215 , A61B5/6851 , A61B8/06 , A61B8/12 , A61M25/09 , A61M25/10 , A61M2025/0002 , A61M2025/09008 , A61M2025/09083 , G01L9/0054 , G01L19/0084 , G01L19/147 , G01L19/149
摘要： A method of measuring blood pressure and velocity proximally and distally of a stenosis in a vessel carrying blood includes the steps of providing a guide wire having both a pressure sensor and a velocity sensor disposed on a distal region of the guide wire, introducing the guide wire into the vessel, advancing the guide wire to position the pressure sensor and the velocity sensor proximally and distally of the stenosis, and measuring the blood pressure and velocity proximally and distally of the stenosis with the pressure sensor and the velocity sensor.
摘要翻译：一种在携带血液的容器中向近端和远端测量血压和速度的方法，包括提供具有设置在导丝的远侧区域上的压力传感器和速度传感器两者的导丝的步骤，将引导线进入容器，推进导丝以将压力传感器和速度传感器定位在近端和远端的狭窄处，并用压力传感器和速度传感器测量近端和远端狭窄的血压和速度。

8. 发明授权

US07967762B2 Ultra miniature pressure sensor 有权
标题翻译：超微型压力传感器
公开(公告)号：US07967762B2
公开(公告)日：2011-06-28
申请号：US11650064
申请日：2007-01-04
申请人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
发明人： Paul D. Corl , Robert Z. Obara , John E. Ortiz
IPC分类号： A61B5/02
CPC分类号： G01L19/141 , A61B5/0215 , A61B5/6851 , A61B8/06 , A61B8/12 , A61M25/09 , A61M25/10 , A61M2025/0002 , A61M2025/09008 , A61M2025/09083 , G01L9/0054 , G01L19/0084 , G01L19/147 , G01L19/149
摘要： A method of measuring blood pressure and velocity proximally and distally of a stenosis in a vessel carrying blood includes the steps of providing a guide wire having both a pressure sensor and a velocity sensor disposed on a distal region of the guide wire, introducing the guide wire into the vessel, advancing the guide wire to position the pressure sensor and the velocity sensor proximally and distally of the stenosis, and measuring the blood pressure and velocity proximally and distally of the stenosis with the pressure sensor and the velocity sensor.
摘要翻译：一种在携带血液的容器中向近端和远端测量血压和速度的方法，包括提供具有设置在导丝的远侧区域上的压力传感器和速度传感器两者的导丝的步骤，将引导线进入容器，推进导丝以将压力传感器和速度传感器定位在近端和远端的狭窄处，并用压力传感器和速度传感器测量近端和远端狭窄的血压和速度。

9. 发明授权

US5523745A Tongue activated communications controller 失效
标题翻译：舌激活通信控制器
公开(公告)号：US5523745A
公开(公告)日：1996-06-04
申请号：US233611
申请日：1994-04-18
申请人： Daniel Fortune , John E. Ortiz , Hien N. Tran
发明人： Daniel Fortune , John E. Ortiz , Hien N. Tran
IPC分类号： A61F4/00 , G09B21/00 , H01H3/14 , H04Q7/00
CPC分类号： G09B21/00 , A61F4/00 , H01H3/14
摘要： A tongue activated communications controller for use by disabled or other persons to control a wide variety of devices, and which includes a dental appliance fitted to the user's palate, and a keyboard with a plurality of tongue activatable switches for generating a signal depending upon which switch has been selected, and upon the status of a battery voltage level. The communications controller includes a radio frequency transmitter which uses magnetic flux linkage for transmitting the signal. The communications controller further includes a receiver for converting the transmitted signal into digital form, and also includes a micro-processor based controller unit for processing the received data, and for communicating with the attached devices which the user wishes to control. Data is sent from the transmitter using a fixed transmission time, digital pulse code modulation technique to achieve ultra low power consumption in the transmitter. The controller unit processes the encoded data signal from the receiver by measuring and storing the intervals between level transitions, and then by processing these intervals in non-real time.
摘要翻译：舌头激活的通信控制器用于由残疾人或其他人使用以控制各种各样的设备，并且其包括安装在用户口蹄上的牙科器具以及具有多个舌状活动开关的键盘，用于根据哪个开关已经被选择，并且在电池电压电平的状态下。通信控制器包括使用磁通链接发送信号的射频发射器。通信控制器还包括用于将所发送的信号转换为数字形式的接收器，还包括用于处理接收到的数据并用于与用户希望控制的附接设备通信的基于微处理器的控制器单元。使用固定传输时间，数字脉冲编码调制技术从发射机发送数据，实现发射机超低功耗。控制器单元通过测量和存储电平转换之间的间隔，然后以非实时处理这些间隔来处理来自接收器的编码数据信号。

10. 发明申请

US20090105802A1 STENT DELIVERY CATHETER 审中-公开
标题翻译： STENT输送管
公开(公告)号：US20090105802A1
公开(公告)日：2009-04-23
申请号：US12337069
申请日：2008-12-17
申请人： William S. Henry , John E. Ortiz
发明人： William S. Henry , John E. Ortiz
IPC分类号： A61F2/06
CPC分类号： A61F2/97 , A61F2/95 , A61F2/966
摘要： A self-expanding stent delivery assembly includes a shaft having a proximal end, a distal end, a distal region, a lumen, and a longitudinal axis. A retractable sheath having an outer surface, a proximal end and a distal end is co-axially disposed around the shaft distal region. A stent is disposed co-axially between the shaft and the retractable sheath. A tubular tapered tip is affixed to the retractable sheath distal end. The tubular tapered tip has an elongate region predisposed to fracturing. Methods of delivering a self-expanding stent are also described.
摘要翻译：自扩张支架输送组件包括具有近端，远端，远侧区域，内腔和纵向轴线的轴。具有外表面，近端和远端的可伸缩护套共轴地设置在轴远侧区域周围。支架同轴地设置在轴和可缩回护套之间。管状锥形尖端固定到可缩回护套远端。管状锥形尖端具有易于断裂的细长区域。还描述了递送自扩张支架的方法。

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