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1. 发明申请

US20160354219A1 BALLOON WITH MANDREL SUPPORT GUIDEWIRE 审中-公开
标题翻译：气球支持GUIDEWIRE
公开(公告)号：US20160354219A1
公开(公告)日：2016-12-08
申请号：US15115522
申请日：2015-01-29
申请人： Gregory Sullivan , Stephen Griffin
发明人： Gregory Sullivan , Stephen Griffin
IPC分类号： A61F2/958 , A61M25/00 , A61M25/01 , A61M25/10
CPC分类号： A61F2/958 , A61M25/0054 , A61M25/0102 , A61M25/104 , A61M2025/0081 , A61M2025/1063 , A61M2025/1084
摘要： A coil-reinforced medical device delivery mechanism including a stiff proximal end for enhanced pushability and a soft distal end, including a free floating tip portion, for increased maneuverability and decreased breakage. The system utilizes a non-compliant balloon mounted on a flexible, single lumen shaft device with a support mandrel construction.
摘要翻译：一种线圈增强医疗装置输送机构，其包括用于增强推力的刚性近端和包括自由浮动尖端部分的软远端，用于增加机动性并减少断裂。该系统使用安装在具有支撑心轴结构的柔性单腔轴装置上的不合规球囊。

2. 发明授权

US08973239B2 Catheter having an ultra soft tip and methods for making the same 有权
标题翻译：导管具有超柔软的尖端和制造相同的方法
公开(公告)号：US08973239B2
公开(公告)日：2015-03-10
申请号：US12906884
申请日：2010-10-18
申请人： Stephen Griffin , Huey Quoc Chan , Elaine Lim , Lex P. Jansen , Anthony F. Tassoni, Jr.
发明人： Stephen Griffin , Huey Quoc Chan , Elaine Lim , Lex P. Jansen , Anthony F. Tassoni, Jr.
IPC分类号： A61F2/958 , A61M25/10 , A61M25/00
CPC分类号： A61M25/10 , A61M25/0069 , A61M2025/1093 , Y10T29/49826
摘要： An intravascular balloon catheter having an ultra soft tip. The catheter includes a braided reinforcement member extending substantially the length of the elongate shaft. A balloon is disposed at the distal end of the elongate shaft. An ultra soft tip is formed from a distal portion of balloon material extending distal of the distal end of the elongate shaft.
摘要翻译：具有超软尖端的血管内气囊导管。导管包括基本上沿细长轴的长度延伸的编织加强件。气球设置在细长轴的远端。超软尖端由从细长轴远端延伸的球囊材料的远端部分形成。

3. 发明授权

US08277438B2 Guide catheter with removable support 有权
标题翻译：导管带可移动支撑
公开(公告)号：US08277438B2
公开(公告)日：2012-10-02
申请号：US12797374
申请日：2010-06-09
申请人： Stephen Griffin , Gregory E. Mirigian
发明人： Stephen Griffin , Gregory E. Mirigian
IPC分类号： A61M25/00
CPC分类号： A61M25/01 , A61M25/104 , A61M2025/0004 , A61M2025/0059 , A61M2025/0681
摘要： Catheters such as guide catheters can be configured for delivery of devices to vasculature portions such as intracranial spaces while retaining a desired level of flexibility. A catheter having an elongate shaft can include removable support means that can provide column support to the elongate shaft. The elongate shaft can include anchoring means that releasably secure the removable support means. The catheter can be deployed within a patient's vasculature, followed by deploying the removable support means.
摘要翻译：诸如引导导管的导管可以被配置为将装置输送到脉管系部分，例如颅内空间，同时保持期望的柔性水平。具有细长轴的导管可以包括可移除的支撑装置，其可以向细长轴提供柱支撑。细长轴可以包括可释放地固定可移除支撑装置的锚固装置。导管可以部署在患者的脉管系统内，随后部署可移除的支撑装置。

4. 发明申请

US20110319928A1 Sacrificial Anode Stent System 失效
标题翻译：牺牲阳极支架系统
公开(公告)号：US20110319928A1
公开(公告)日：2011-12-29
申请号：US13227202
申请日：2011-09-07
申请人： Stephen Griffin , Brent C. Gerberding
发明人： Stephen Griffin , Brent C. Gerberding
IPC分类号： A61F2/01 , A61F2/82
CPC分类号： A61F2/91 , A61B17/12022 , A61B17/12036 , A61B17/12118 , A61B17/1214 , A61B2017/12063 , A61F2/915 , A61F2002/3008 , A61F2002/823 , A61F2002/91541 , A61F2002/91558 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2250/0054 , A61F2250/0098 , Y10S623/903
摘要： A sacrificial anode stent system comprises a stent having at least one sacrificial anode portion and a vaso-occlusive device. The vaso-occlusive device has at least one portion with a potential different from that of the sacrificial anode portion of the stent.
摘要翻译：牺牲阳极支架系统包括具有至少一个牺牲阳极部分和血管闭塞装置的支架。血管闭塞装置具有与支架的牺牲阳极部分不同的潜力的至少一部分。

5. 发明授权

US07918806B2 Guide wire with adjustable flexibility 有权
标题翻译：导丝可调节灵活
公开(公告)号：US07918806B2
公开(公告)日：2011-04-05
申请号：US11352753
申请日：2006-02-13
申请人： Stephen Griffin , Gregory E. Mirigian
发明人： Stephen Griffin , Gregory E. Mirigian
IPC分类号： A61M25/00
CPC分类号： A61M25/09 , A61M2025/0915 , A61M2025/09175
摘要： A guide wire with a distal portion having adjustable flexibility. The guide wire may include a distal polymeric member and a heat source. The heat source may be activated to cause the polymeric member to increase in temperature and increase in flexibility. The increase in flexibility of the distal portion of the guide wire enhances the ability of the guide wire to navigate tortuous vasculature to a target site. After the guide wire has been navigated to the target site, the heat source may be deactivated to cause the polymeric member to decrease in temperature and increase in stiffness. The increase in stiffness of the distal portion of the guide wire enhances support provided for devices (e.g., catheters) advanced thereon.
摘要翻译：导丝，其具有可调节的柔性的远端部分。导丝可以包括远端聚合物构件和热源。可以激活热源以使聚合物部件的温度升高并且柔性增加。引导线的远端部分的柔性的增加增强了引导线将弯曲脉管系统导航到目标部位的能力。在引导线已经导航到目标部位之后，热源可以被去活，以使聚合物部件降低温度并增加刚度。引导线的远端部分的刚度的增加增强了对在其上推进的装置（例如，导管）提供的支撑。

6. 发明申请

US20110034989A1 RAPID-EXCHANGE BALLOON CATHETER SHAFT AND METHOD 有权
标题翻译：快速交换气囊导管轴和方法
公开(公告)号：US20110034989A1
公开(公告)日：2011-02-10
申请号：US12906976
申请日：2010-10-18
申请人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
发明人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
IPC分类号： A61F2/84
CPC分类号： A61M25/10 , A61F2/915 , A61F2/958 , A61F2002/91558 , A61F2230/0054 , A61F2250/0018 , A61M25/0054 , A61M2025/0183
摘要： A balloon catheter or stent delivery system for medical treatment of a patient has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a rapid-exchange configuration, and a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near a proximal leg of the balloon. An inner tubular body defines a guidewire lumen extending from a distal guidewire port at the catheter distal end to a proximal port located at a position between the balloon and the hub. A distal leg of the balloon is directly or indirectly affixed to the inner body, and a proximal leg of the balloon is affixed to the distal end of the outer body. The hypotube has an aperture for accepting the inner body proximal end, and a circumferential cut pattern. The cut pattern adds flexibility, and may extend from the hypotube distal end to a position proximal of the proximal guidewire port. The cut pattern may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The hypotube has a fluid-tight covering such as a heat-shrink polymer, so the outer body supports pressure of an inflation medium. The proximal guidewire port may be positioned on or between the individual portions of the cut pattern, or at a position beyond the cut pattern.
摘要翻译：用于患者医疗的球囊导管或支架输送系统具有近端毂，球囊和改进的轴设计。导管轴具有快速交换构造，以及管状外体，其包括从导管近端延伸到球囊的近端腿处或附近的位置的海波管。内部管状体限定从导管远端处的远端导丝端口延伸到位于气囊和轮毂之间的位置的近端口的导丝管腔。球囊的远端腿直接或间接地固定到内体上，并且气球的近端腿固定到外体的远端。海波管具有用于接纳内体近端的孔和圆周切割图案。切割图案增加了柔性，并且可以从海波管远端延伸到近端导丝端口的近端。切割图案可以具有任何期望的形状，例如包括螺旋形，螺旋形起伏路径或具有拐点的重叠蛇形路径。海波管具有流体密封的覆盖物，例如热收缩聚合物，因此外壳支撑膨胀介质的压力。近端导丝端口可以定位在切割图案的各个部分之间或之间，或位于切割图案之外的位置。

7. 发明授权

US07815600B2 Rapid-exchange balloon catheter shaft and method 有权
标题翻译：快速交换球囊导管轴和方法
公开(公告)号：US07815600B2
公开(公告)日：2010-10-19
申请号：US12008509
申请日：2008-01-11
申请人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
发明人： Laila Al-Marashi , David Grewe , Stephen Griffin , Elaine Lim , David Majercak , Roger Stevens
IPC分类号： A61M31/00
CPC分类号： A61M25/10 , A61F2/915 , A61F2/958 , A61F2002/91558 , A61F2230/0054 , A61F2250/0018 , A61M25/0054 , A61M2025/0183
摘要： A rapid-exchange balloon catheter or stent delivery system, for medically treating a patient, has a proximal hub, a balloon, and an improved shaft design. The catheter shaft has a tubular outer body that includes a hypotube extending from the catheter proximal end to a position at or near the proximal leg of the balloon. An inner tubular body defines a guidewire lumen and extends from a distal guidewire port at the catheter distal end to proximal guidewire port located between the balloon and the proximal hub. The hypotube has an aperture for accepting the inner body proximal end and a circumferential cut pattern. The cut pattern adds flexibility and may have any desired shape, including a spiral, a helical undulating path, or an overlapping serpentine path with inflection points, for example. The proximal guidewire port may be positioned on or in between the individual portions of the cut pattern.
摘要翻译：用于医疗治疗患者的快速交换气囊导管或支架输送系统具有近端毂，球囊和改进的轴设计。导管轴具有管状外体，其包括从导管近端延伸到球囊近端腿处或附近的位置的海波管。内管状体限定了导丝内腔，并且从导管远端处的远端导丝端口延伸到位于气囊和近端毂之间的近端导丝端口。海波管具有用于接纳内体近端和圆周切割图案的孔。切割图案增加了柔性，并且可以具有任何期望的形状，例如包括螺旋形，螺旋形波形路径或具有拐点的重叠蛇形路径。近端导丝端口可以定位在切割图案的各个部分之间或之中。

8. 发明授权

US07670302B2 Super elastic guidewire with shape retention tip 有权
标题翻译：具有形状保持尖端的超弹性导丝
公开(公告)号：US07670302B2
公开(公告)日：2010-03-02
申请号：US10025668
申请日：2001-12-18
申请人： Stephen Griffin , Ronald A. Saharjian
发明人： Stephen Griffin , Ronald A. Saharjian
IPC分类号： A61M25/00
CPC分类号： A61L31/022 , A61L31/10 , A61L2400/16 , A61M25/09 , A61M2025/09141
摘要： A guidewire having a super elastic core surrounded by a shape memory polymer jacket. The super elastic core wire permits the guidewire to be navigated through tortuous vasculature without undergoing plastic deformation, and the shape memory polymer jacket permits the guidewire to be shaped by the physician.
摘要翻译：具有由形状记忆聚合物护套包围的超弹性芯的导丝。超弹性芯线允许导丝通过曲折的脉管系统导航，而不会发生塑性变形，并且形状记忆聚合物护套允许导线由医生成形。

9. 发明申请

US20100004671A1 METHODS AND DEVICES FOR THE TREATMENT OF ANEURYSMS 有权
标题翻译：用于治疗神经系统的方法和装置
公开(公告)号：US20100004671A1
公开(公告)日：2010-01-07
申请号：US12489158
申请日：2009-06-22
申请人： Brent Gerberding , Stephen Griffin , Yem Chin , Jennifer Jandak , Anthony R. Tremaglio, JR. , Lee Guterman , Alyssa Dassa , Richard Hudson
发明人： Brent Gerberding , Stephen Griffin , Yem Chin , Jennifer Jandak , Anthony R. Tremaglio, JR. , Lee Guterman , Alyssa Dassa , Richard Hudson
IPC分类号： A61M29/00
CPC分类号： A61B17/12113 , A61B17/0057 , A61B17/12022 , A61B17/12036 , A61B17/1204 , A61B17/12118 , A61B17/12172 , A61B17/12186 , A61B90/39 , A61B2017/00867 , A61B2017/12063 , A61B2090/065
摘要： A device for at least partially occluding an aneurysm is disclosed. The device includes a first elongate member having a distal end. A bridge is positioned proximate the distal end and transformable between a delivery configuration and a deployed configuration. A second elongate member is movable relative to the first elongate member, the first and second elongate members being configured such that one can be moved relative to the other in order to transform the bridge between the delivery and deployed configurations.
摘要翻译：公开了一种用于至少部分闭塞动脉瘤的装置。该装置包括具有远端的第一细长构件。桥接器定位在远端附近并且可在传送配置和部署配置之间进行变换。第二细长构件相对于第一细长构件是可移动的，第一和第二细长构件被构造成使得一个可以相对于另一个移动，以便在递送和展开配置之间转换桥梁。

10. 发明授权

US07632242B2 Catheter including a compliant balloon 有权
标题翻译：导管包括顺应气球
公开(公告)号：US07632242B2
公开(公告)日：2009-12-15
申请号：US11008452
申请日：2004-12-09
申请人： Stephen Griffin , Huey Quoc Chan , Elaine Lim , Nhan Hue To
发明人： Stephen Griffin , Huey Quoc Chan , Elaine Lim , Nhan Hue To
IPC分类号： A61M29/00
CPC分类号： A61M25/1002 , A61B17/22032 , A61M25/0054 , A61M25/0105 , A61M25/10
摘要： A catheter having an elongate shaft including a plurality of apertures disposed along at least a length of the shaft to facilitate bending. The catheter includes an inflatable balloon, wherein a subset of the plurality of apertures provides fluid communication from an inflation lumen to the inflatable balloon.
摘要翻译：一种具有细长轴的导管，包括沿轴的至少一段长度设置的多个孔，以便于弯曲。导管包括可充气气囊，其中多个孔的子集提供从充气腔向可膨胀气囊的流体连通。

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