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1. 发明申请

US20050137524A1 Ductal lavage catheter having an off-axis tip 失效
标题翻译：具有离轴尖端的导管灌洗导管
公开(公告)号：US20050137524A1
公开(公告)日：2005-06-23
申请号：US10746950
申请日：2003-12-23
申请人： Robert Sakal , Ellen Sheets , Meghan Brennan , Greg Furnish , Charles Whatley , Ben Morris , Indi Gunasekara
发明人： Robert Sakal , Ellen Sheets , Meghan Brennan , Greg Furnish , Charles Whatley , Ben Morris , Indi Gunasekara
IPC分类号： A61B10/00 , A61B17/22 , A61B17/34 , A61M1/00 , A61M25/00 , A61M31/00
CPC分类号： A61M25/0068 , A61B10/0041 , A61B10/0045 , A61B17/3421 , A61B2017/22074 , A61B2217/005 , A61M25/008 , A61M2025/0073
摘要： A ductal access device is provided for accessing a breast duct and collecting biological material from within the duct. The access device may include an elongated member having an outer diameter sized for positioning within the breast duct and an internal lumen for infusing a fluid into the breast duct and collecting fluid from the breast duct. The elongated member may include a central axis extending through the internal lumen and a different axis being parallel to the central axis defining an off-axis configuration. An elongated distal tip extends beyond the distal end of the internal lumen and along the different axis. The elongated distal tip has a closed distal end for navigating within the breast duct. The elongated distal tip may include an internal passageway that is sized to slidiably or removably receive an elongated introducer.
摘要翻译：提供导管进入装置用于进入乳房管道并从管道内收集生物材料。进入装置可以包括细长构件，其具有尺寸适于定位在乳房管道内的外径和用于将流体输入乳房管道并从乳房管道收集流体的内腔。细长构件可以包括延伸穿过内部内腔的中心轴线，并且不同的轴线平行于限定离轴构造的中心轴线。细长的远端尖端延伸超过内腔的远端并沿着不同的轴线。细长的远侧末端具有用于在乳房导管内导航的封闭远端。细长的远侧末端可以包括内部通道，其尺寸设计成可滑动地或可移除地容纳细长的导引器。

2. 发明申请

US20050137498A1 Medical instrument for accessing a breast duct for performing a medical procedure 有权
标题翻译：用于进行执行医疗程序的乳房管道的医疗器械
公开(公告)号：US20050137498A1
公开(公告)日：2005-06-23
申请号：US10746128
申请日：2003-12-23
申请人： Robert Sakal , Meghan Brennan , Greg Furnish , Charles Whatley , Ben Morris
发明人： Robert Sakal , Meghan Brennan , Greg Furnish , Charles Whatley , Ben Morris
IPC分类号： A61B10/00 , A61B19/00 , A61M1/00 , A61M1/06
CPC分类号： A61M1/0058 , A61B10/0041 , A61B10/0045 , A61B2090/034
摘要： A medical instrument including a ductal access device comprising a low profile, ergonomic manifold hub usable to introduce fluids into a breast duct and collect ductal fluid samples including ductal epithelial cells and clumps of ductal epithelial cells from within a breast duct. The ductal access device also comprises an elongated access catheter having a distal end, one lumen and dimensions which permit introduction of the distal end through a ductal orifice so that a distal end of the catheter may be positioned distal to the ductal sphincter of a human breast. The medical instrument may also include at least one spacing member for adjustably positioning the manifold hub a desired distance above the surface of the nipple. The spacing member may control the insertion depth of the catheter into the duct. The medical instrument may also include at least one member for anchoring the device to the breast.
摘要翻译：一种医疗器械，其包括导管进入装置，其包括用于将流体引入乳房导管中的低轮廓人体工程学的歧管轮毂，并从乳房导管内收集包括导管上皮细胞和导管上皮细胞团的导管流体样品。导管进入装置还包括细长的进入导管，其具有远端，一个内腔和尺寸，其允许远端通过导管孔引入，使得导管的远端可位于人乳房的导管括约肌的远侧。医疗器械还可以包括至少一个间隔构件，用于将歧管座可调节地定位在乳头表面上方所需的距离。间隔构件可以将导管的插入深度控制在管道中。医疗器械还可以包括用于将装置锚定到乳房的至少一个构件。

3. 发明申请

US20070035042A1 Medical instrument for accessing a breast duct for performing a medical procedure 审中-公开
标题翻译：用于进行执行医疗程序的乳房管道的医疗器械
公开(公告)号：US20070035042A1
公开(公告)日：2007-02-15
申请号：US11504995
申请日：2006-08-16
申请人： Robert Sakal , Meghan Brennan , Greg Furnish , Charles Whatley , Ben Morris
发明人： Robert Sakal , Meghan Brennan , Greg Furnish , Charles Whatley , Ben Morris
IPC分类号： B01D47/00
CPC分类号： A61M1/0058 , A61B10/0041 , A61B10/0045 , A61B2090/034
摘要： A medical instrument including a ductal access device comprising a low profile, ergonomic manifold hub usable to introduce fluids into a breast duct and collect ductal fluid samples including ductal epithelial cells and clumps of ductal epithelial cells from within a breast duct. The ductal access device also comprises an elongated access catheter having a distal end, one lumen and dimensions which permit introduction of the distal end through a ductal orifice so that a distal end of the catheter may be positioned distal to the ductal sphincter of a human breast. The medical instrument may also include at least one spacing member for adjustably positioning the manifold hub a desired distance above the surface of the nipple. The spacing member may control the insertion depth of the catheter into the duct. The medical instrument may also include at least one member for anchoring the device to the breast.
摘要翻译：一种医疗器械，其包括导管进入装置，其包括用于将流体引入乳房导管中的低轮廓人体工程学的歧管轮毂，并从乳房导管内收集包括导管上皮细胞和导管上皮细胞团的导管流体样品。导管进入装置还包括细长的进入导管，其具有远端，一个内腔和尺寸，其允许远端通过导管孔引入，使得导管的远端可位于人乳房的导管括约肌的远侧。医疗器械还可以包括至少一个间隔构件，用于将歧管座可调节地定位在乳头表面上方所需的距离。间隔构件可以将导管的插入深度控制在管道中。医疗器械还可以包括用于将装置锚定到乳房的至少一个构件。

4. 发明申请

US20060195065A1 Ductal lavage microcatheter with user activated valve and nitinol introducer 审中-公开
标题翻译：导管灌洗微导管，用户激活阀和镍钛诺导引器
公开(公告)号：US20060195065A1
公开(公告)日：2006-08-31
申请号：US11415029
申请日：2006-05-01
申请人： Robert Sakal , Meghan Brennan , Douglas Macarthur , Ben Morris , Todd Hall , Simon Furnish
发明人： Robert Sakal , Meghan Brennan , Douglas Macarthur , Ben Morris , Todd Hall , Simon Furnish
IPC分类号： A61M5/178 , A61B5/00 , B65D81/00 , F16K7/04
CPC分类号： A61M25/01 , A61B10/0041 , A61B10/0045 , A61M25/0102 , A61M39/06 , A61M2025/0042 , A61M2210/1007
摘要： A medical instrument including a ductal access device comprising a low profile, ergonomic manifold hub usable to introduce fluids into a breast duct and collect ductal fluid samples including ductal epithelial cells and clumps of ductal epithelial cells from within a breast duct. The ductal access device also comprises an elongated access catheter having a distal end, one lumen and dimensions which permit introduction of the distal end through a ductal orifice so that a distal end of the catheter may be positioned distal to the ductal sphincter of a human breast. The medical instrument may also include and activate valve and a Nitinol introducer.
摘要翻译：一种医疗器械，其包括导管进入装置，其包括用于将流体引入乳房导管中的低轮廓人体工程学的歧管轮毂，并从乳房导管内收集包括导管上皮细胞和导管上皮细胞团的导管流体样品。导管进入装置还包括细长的进入导管，其具有远端，一个内腔和尺寸，其允许远端通过导管孔引入，使得导管的远端可位于人乳房的导管括约肌的远侧。医疗器械还可以包括并激活阀和镍钛诺导入器。

5. 发明申请

US20050137574A1 Ductal lavage microcatheter with user activated valve and Nitinol introducer 有权
标题翻译：导管灌洗微导管与用户激活阀和镍钛杆菌导引器
公开(公告)号：US20050137574A1
公开(公告)日：2005-06-23
申请号：US10746117
申请日：2003-12-23
申请人： Robert Sakal , Meghan Brennan , Douglas Macarthur , Ben Morris , Todd Hall , Simon Furnish
发明人： Robert Sakal , Meghan Brennan , Douglas Macarthur , Ben Morris , Todd Hall , Simon Furnish
IPC分类号： A61B10/00 , A61M31/00
CPC分类号： A61M25/01 , A61B10/0041 , A61B10/0045 , A61M25/0102 , A61M39/06 , A61M2025/0042 , A61M2210/1007
摘要： A medical instrument including a ductal access device comprising a low profile, ergonomic manifold hub usable to introduce fluids into a breast duct and collect ductal fluid samples including ductal epithelial cells and clumps of ductal epithelial cells from within a breast duct. The ductal access device also comprises an elongated access catheter having a distal end, one lumen and dimensions which permit introduction of the distal end through a ductal orifice so that a distal end of the catheter may be positioned distal to the ductal sphincter of a human breast. The medical instrument may also include and activate valve and a Nitinol introducer.
摘要翻译：一种医疗器械，其包括导管进入装置，其包括用于将流体引入乳房导管中的低轮廓人体工程学的歧管轮毂，并从乳房导管内收集包括导管上皮细胞和导管上皮细胞团的导管流体样品。导管进入装置还包括细长的进入导管，其具有远端，一个内腔和尺寸，其允许远端通过导管孔引入，使得导管的远端可位于人乳房的导管括约肌的远侧。医疗器械还可以包括并激活阀和镍钛诺导入器。

6. 发明申请

US20070150002A1 Systems and methods for closing a vessel wound 有权
标题翻译：关闭容器伤口的系统和方法
公开(公告)号：US20070150002A1
公开(公告)日：2007-06-28
申请号：US11317478
申请日：2005-12-23
申请人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael Trezza
发明人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael Trezza
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B2017/00004 , A61B2017/00367 , A61B2017/00637 , A61B2017/00659 , A61B2017/0404 , A61B2017/0414 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/06176
摘要： Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravascularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.
摘要翻译：血管伤口闭合系统和密封目标血管中穿刺伤口的方法，例如从先前介入手术发生的那些穿刺伤口。密封构件在血管内部署到靶容器中，并且锚定构件部署在靶血管的血管外。密封构件和锚定构件通过缝合线连接，缝合线可以被拉伸以将密封构件和锚定构件相对于彼此紧固，以便实现穿刺伤口的密封。紧固后，缝合线被固定以保持密封构件和锚固构件相对于彼此以便保持密封。优选地，锚固构件，缝合线和密封构件由生物相容的生物可再吸收材料构成，其在已经实现了穿刺伤口的密封之后被吸收到身体中。密封构件，缝合线和锚固构件通过导线或通过导引器的输送杆或其它部件从前述介入过程传送。

7. 发明授权

US09504457B2 Systems and methods for closing a vessel wound 有权
标题翻译：关闭容器伤口的系统和方法
公开(公告)号：US09504457B2
公开(公告)日：2016-11-29
申请号：US13183603
申请日：2011-07-15
申请人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
发明人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
IPC分类号： A61B17/08 , A61B17/00 , A61B17/04 , A61B17/06
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B2017/00004 , A61B2017/00367 , A61B2017/00637 , A61B2017/00659 , A61B2017/0404 , A61B2017/0414 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/06176
摘要： Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravacularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.
摘要翻译：血管伤口闭合系统和密封目标血管中穿刺伤口的方法，例如从先前介入手术发生的那些穿刺伤口。密封构件在血管内部署到靶容器中，并且锚定构件被部署在目标血管的外侧。密封构件和锚定构件通过缝合线连接，缝合线可以被拉伸以将密封构件和锚定构件相对于彼此紧固，以便实现穿刺伤口的密封。紧固后，缝合线被固定以保持密封构件和锚固构件相对于彼此以便保持密封。优选地，锚固构件，缝合线和密封构件由生物相容的生物可再吸收材料构成，其在已经实现了穿刺伤口的密封之后被吸收到身体中。密封构件，缝合线和锚固构件通过导线或通过导引器的输送杆或其它部件从前述介入过程传送。

8. 发明授权

US08267942B2 Systems and methods for closing a vessel wound 有权
标题翻译：关闭容器伤口的系统和方法
公开(公告)号：US08267942B2
公开(公告)日：2012-09-18
申请号：US11317478
申请日：2005-12-23
申请人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
发明人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B2017/00004 , A61B2017/00367 , A61B2017/00637 , A61B2017/00659 , A61B2017/0404 , A61B2017/0414 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/06176
摘要： Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravascularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.
摘要翻译：血管伤口闭合系统和密封目标血管中穿刺伤口的方法，例如从先前介入手术发生的那些穿刺伤口。密封构件在血管内部署到靶容器中，并且锚定构件部署在靶血管的血管外。密封构件和锚定构件通过缝合线连接，缝合线可以被拉伸以将密封构件和锚定构件相对于彼此紧固，以便实现穿刺伤口的密封。紧固后，缝合线被固定以保持密封构件和锚固构件相对于彼此以便保持密封。优选地，锚固构件，缝合线和密封构件由生物相容的生物可再吸收材料构成，其在已经实现了穿刺伤口的密封之后被吸收到身体中。密封构件，缝合线和锚固构件通过导线或通过导引器的输送杆或其它部件从前述介入过程传送。

9. 发明申请

US20110270307A1 SYSTEMS AND METHODS FOR CLOSING A VESSEL WOUND 审中-公开
标题翻译：用于封闭船只的系统和方法
公开(公告)号：US20110270307A1
公开(公告)日：2011-11-03
申请号：US13183603
申请日：2011-07-15
申请人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
发明人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B2017/00004 , A61B2017/00367 , A61B2017/00637 , A61B2017/00659 , A61B2017/0404 , A61B2017/0414 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/06176
摘要： Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravascularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.
摘要翻译：血管伤口闭合系统和密封目标血管中穿刺伤口的方法，例如从先前介入手术发生的那些穿刺伤口。密封构件在血管内部署到靶容器中，并且锚定构件部署在靶血管的血管外。密封构件和锚定构件通过缝合线连接，缝合线可以被拉伸以将密封构件和锚定构件相对于彼此紧固，以便实现穿刺伤口的密封。紧固后，缝合线被固定以保持密封构件和锚固构件相对于彼此以便保持密封。优选地，锚固构件，缝合线和密封构件由生物相容的生物可再吸收材料构成，其在已经实现了穿刺伤口的密封之后被吸收到身体中。密封构件，缝合线和锚固构件通过导线或通过导引器的输送杆或其它部件从前述介入过程传送。

10. 发明申请

US20110152842A1 Drainage Catheter Tip Shape Configuration 有权
标题翻译：排水导管尖端形状配置
公开(公告)号：US20110152842A1
公开(公告)日：2011-06-23
申请号：US12641265
申请日：2009-12-17
申请人： Richard Graffam , Ben Morris , Chuck Bourgeois
发明人： Richard Graffam , Ben Morris , Chuck Bourgeois
IPC分类号： A61M27/00 , A61M25/09
CPC分类号： A61M25/0102 , A61M25/0017 , A61M25/0041 , A61M25/0052 , A61M25/007 , A61M25/04 , A61M27/00 , A61M2025/0163
摘要： A percutaneous catheter includes a longitudinal catheter shaft having a distal end, a proximal end, a hollow portion, and a wall portion, a wire embedded within said wall portion at said distal end wherein said wire forms a pigtail curve when in a relaxed state, and a stylet capable of entering said hollow portion of said longitudinal catheter at said proximal end wherein said stylet substantially straightens said longitudinal catheter at said distal end.
摘要翻译：经皮导管包括具有远端，近端，中空部分和壁部分的纵向导管轴，在所述远端处嵌入所述壁部分内的线，其中当处于松弛状态时，所述线形成猪尾线曲线，以及能够在所述近端进入所述纵向导管的所述中空部分的探针，其中所述探针在所述远端基本上拉直所述纵向导管。

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