专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US09504457B2 Systems and methods for closing a vessel wound 有权
标题翻译：关闭容器伤口的系统和方法
公开(公告)号：US09504457B2
公开(公告)日：2016-11-29
申请号：US13183603
申请日：2011-07-15
申请人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
发明人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
IPC分类号： A61B17/08 , A61B17/00 , A61B17/04 , A61B17/06
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B2017/00004 , A61B2017/00367 , A61B2017/00637 , A61B2017/00659 , A61B2017/0404 , A61B2017/0414 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/06176
摘要： Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravacularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.
摘要翻译：血管伤口闭合系统和密封目标血管中穿刺伤口的方法，例如从先前介入手术发生的那些穿刺伤口。密封构件在血管内部署到靶容器中，并且锚定构件被部署在目标血管的外侧。密封构件和锚定构件通过缝合线连接，缝合线可以被拉伸以将密封构件和锚定构件相对于彼此紧固，以便实现穿刺伤口的密封。紧固后，缝合线被固定以保持密封构件和锚固构件相对于彼此以便保持密封。优选地，锚固构件，缝合线和密封构件由生物相容的生物可再吸收材料构成，其在已经实现了穿刺伤口的密封之后被吸收到身体中。密封构件，缝合线和锚固构件通过导线或通过导引器的输送杆或其它部件从前述介入过程传送。

2. 发明授权

US08267942B2 Systems and methods for closing a vessel wound 有权
标题翻译：关闭容器伤口的系统和方法
公开(公告)号：US08267942B2
公开(公告)日：2012-09-18
申请号：US11317478
申请日：2005-12-23
申请人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
发明人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B2017/00004 , A61B2017/00367 , A61B2017/00637 , A61B2017/00659 , A61B2017/0404 , A61B2017/0414 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/06176
摘要： Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravascularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.
摘要翻译：血管伤口闭合系统和密封目标血管中穿刺伤口的方法，例如从先前介入手术发生的那些穿刺伤口。密封构件在血管内部署到靶容器中，并且锚定构件部署在靶血管的血管外。密封构件和锚定构件通过缝合线连接，缝合线可以被拉伸以将密封构件和锚定构件相对于彼此紧固，以便实现穿刺伤口的密封。紧固后，缝合线被固定以保持密封构件和锚固构件相对于彼此以便保持密封。优选地，锚固构件，缝合线和密封构件由生物相容的生物可再吸收材料构成，其在已经实现了穿刺伤口的密封之后被吸收到身体中。密封构件，缝合线和锚固构件通过导线或通过导引器的输送杆或其它部件从前述介入过程传送。

3. 发明授权

US09474645B2 Punctal plugs for the delivery of active agents 有权
标题翻译：用于递送活性剂的针刺塞
公开(公告)号：US09474645B2
公开(公告)日：2016-10-25
申请号：US11759269
申请日：2007-06-07
申请人： Han Cui , Zhigang Li , Edgar V. Menezes , Aruna Nathan , Michael J. Trezza, II
发明人： Han Cui , Zhigang Li , Edgar V. Menezes , Aruna Nathan , Michael J. Trezza, II
IPC分类号： A61F2/00 , A61F13/00 , A61F2/14 , A61F9/00 , A61F9/007 , A61K9/00
CPC分类号： A61F9/0017 , A61F9/00772 , A61K9/0051
摘要： The invention provides punctal plugs for the delivery of active agent to one or both of the tear fluid of the eye and to the nasolacrimal duct that comprise a body, at least one cap, and optionally a collarette.
摘要翻译：本发明提供了用于将活性剂递送到眼睛的泪液和包括身体，至少一个帽和任选的肩胛骨的鼻泪管的一个或两个的泪点。

4. 发明申请

US20130164347A1 MULTILAYER POLYMERIC DRUG DELIVERY SYSTEM 审中-公开
标题翻译：多层聚合物药物输送系统
公开(公告)号：US20130164347A1
公开(公告)日：2013-06-27
申请号：US13724483
申请日：2012-12-21
申请人： Michel Gensini , Michael J. Trezza, II , Abla Abu-Zayyad Creasey
发明人： Michel Gensini , Michael J. Trezza, II , Abla Abu-Zayyad Creasey
IPC分类号： A61K9/00
CPC分类号： A61L15/44 , A61K9/7084 , A61L15/28 , A61L2300/602 , C08L1/26
摘要： The invention relates to a customizable, solvent-free sustained release medical device for wound closure, wound healing, and the sustained release of an active. The device of the invention is composed of at least a polymeric carrier layer and optionally an oxidized regenerated cellulose layer(s). Polymeric barrier layers can be added to modify the release profile (burst, time of release, etc.) of the selected bioactive agent(s).
摘要翻译：本发明涉及可定制的无溶剂的持续释放医疗装置，用于伤口闭合，伤口愈合和活性物质的持续释放。本发明的装置由至少一种聚合物载体层和任选的氧化再生纤维素层组成。可以加入聚合物阻挡层以改变所选择的生物活性剂的释放曲线（爆发，释放时间等）。

5. 发明申请

US20110270307A1 SYSTEMS AND METHODS FOR CLOSING A VESSEL WOUND 审中-公开
标题翻译：用于封闭船只的系统和方法
公开(公告)号：US20110270307A1
公开(公告)日：2011-11-03
申请号：US13183603
申请日：2011-07-15
申请人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
发明人： David Szabo , David Gale , Paul Johnson , Valerie Scott , Ben Morris , Greg Furnish , Trevor Beckett , Michael J. Trezza, II
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B2017/00004 , A61B2017/00367 , A61B2017/00637 , A61B2017/00659 , A61B2017/0404 , A61B2017/0414 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/06176
摘要： Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravascularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.
摘要翻译：血管伤口闭合系统和密封目标血管中穿刺伤口的方法，例如从先前介入手术发生的那些穿刺伤口。密封构件在血管内部署到靶容器中，并且锚定构件部署在靶血管的血管外。密封构件和锚定构件通过缝合线连接，缝合线可以被拉伸以将密封构件和锚定构件相对于彼此紧固，以便实现穿刺伤口的密封。紧固后，缝合线被固定以保持密封构件和锚固构件相对于彼此以便保持密封。优选地，锚固构件，缝合线和密封构件由生物相容的生物可再吸收材料构成，其在已经实现了穿刺伤口的密封之后被吸收到身体中。密封构件，缝合线和锚固构件通过导线或通过导引器的输送杆或其它部件从前述介入过程传送。

6. 发明申请

US20110022007A1 OPHTHALMIC DEVICES FOR THE CONTROLLED RELEASE OF ACTIVE AGENTS 有权
标题翻译：用于控制释放活性剂的透明设备
公开(公告)号：US20110022007A1
公开(公告)日：2011-01-27
申请号：US12779238
申请日：2010-05-13
申请人： Zhigang Li , Michael J. Trezza, II , Maureen J. Borgia , Aruna Nathan , Bret A. Coldren
发明人： Zhigang Li , Michael J. Trezza, II , Maureen J. Borgia , Aruna Nathan , Bret A. Coldren
IPC分类号： A61F9/00
CPC分类号： A61F9/0017 , A61F9/00772 , A61F2250/0068 , A61K9/0043 , A61K9/0051
摘要： The invention provides devices useful for the delivery of active agents to the eye in a controlled manner. In the devices of the invention, the active agent is present within the device in a continuous or discontinuous concentration gradient.
摘要翻译：本发明提供了用于以受控方式将活性剂递送至眼睛的装置。在本发明的装置中，活性剂以连续或不连续的浓度梯度存在于装置内。

7. 发明授权

US09173773B2 Punctal plugs for the delivery of active agents 有权
标题翻译：用于递送活性剂的针刺塞
公开(公告)号：US09173773B2
公开(公告)日：2015-11-03
申请号：US11759327
申请日：2007-06-07
申请人： Maureen J. Borgia , Hassan Chaouk , Han Cui , Walter Laredo , Zhigang Li , Aruna Nathan , Michael J. Trezza, II
发明人： Maureen J. Borgia , Hassan Chaouk , Han Cui , Walter Laredo , Zhigang Li , Aruna Nathan , Michael J. Trezza, II
IPC分类号： A61F2/00 , A61F13/00 , A61F9/007 , A61F9/00 , A61M31/00
CPC分类号： A61F9/00772 , A61F9/0017 , A61M31/002
摘要： The invention provides punctal plugs for the delivery of active agent to one or both of the tear fluid of the eye and to the nasolacrimal duct. The plugs of the invention have a body, a reservoir contained within the body, and optionally a collarette. The reservoir has at least one opening and contains a polymeric material and at least one active agent.
摘要翻译：本发明提供了用于将活性剂递送到眼睛的泪液和鼻泪管中的一种或两种的泪点塞。本发明的塞子具有主体，容纳在主体内的储存器，以及可选地是围兜。储存器具有至少一个开口并且包含聚合材料和至少一种活性剂。

8. 发明授权

US08377042B2 Ophthalmic devices for the controlled release of active agents 有权
标题翻译：用于控释活性剂的眼科装置
公开(公告)号：US08377042B2
公开(公告)日：2013-02-19
申请号：US12779238
申请日：2010-05-13
申请人： Zhigang Li , Michael J. Trezza, II , Maureen J. Borgia , Aruna Nathan , Bret A. Coldren
发明人： Zhigang Li , Michael J. Trezza, II , Maureen J. Borgia , Aruna Nathan , Bret A. Coldren
IPC分类号： A61K9/22
CPC分类号： A61F9/0017 , A61F9/00772 , A61F2250/0068 , A61K9/0043 , A61K9/0051
摘要： The invention provides devices useful for the delivery of active agents to the eye in a controlled manner. In the devices of the invention, the active agent is present within the device in a continuous or discontinuous concentration gradient.
摘要翻译：本发明提供了用于以受控方式将活性剂递送至眼睛的装置。在本发明的装置中，活性剂以连续或不连续的浓度梯度存在于装置内。

9. 发明授权

US08337415B2 Tissue harvesting, mincing, and transport device 失效
标题翻译：组织收割，切碎和运输装置
公开(公告)号：US08337415B2
公开(公告)日：2012-12-25
申请号：US12709738
申请日：2010-02-22
申请人： Michael J. Trezza, II , John A. Hibner , Joseph C. Hueil , Patrick A. Mescher
发明人： Michael J. Trezza, II , John A. Hibner , Joseph C. Hueil , Patrick A. Mescher
IPC分类号： A61B10/00
CPC分类号： A61B17/320016 , A61B10/0275 , A61B10/0283 , A61B2010/0208
摘要： A device comprises a needle, probe, holster, and tissue collection chamber. A motor simultaneously powers a vacuum pump, translates and rotates a cutter, and translates a plunger. The needle includes a piercing tip and an interior shelf that divides the needle into a cutter lumen and lateral lumen. The cutter and shelf include apertures configured to mince a portion of a tissue specimen that has been severed by the cutter and forced through the apertures by compressive force from the plunger as well as vacuum force. The apertures of the shelf and the apertures of the rotating cutter cooperate to shear the tissue being compressed by the plunger. The minced tissue is then transported to the tissue collection chamber under vacuum force with the assistance of a fluid flush. Collected minced tissue may then be further processed as desired for a given medical treatment or procedure.
摘要翻译：一种装置包括针，探针，皮套和组织收集室。马达同时为真空泵供电，平移和旋转切割器，并平移柱塞。针包括穿刺尖端和将针分成切割器腔和侧腔的内部搁架。切割器和搁板包括孔，该孔被构造成切割由切割器切断的组织样本的一部分并且通过来自柱塞的压力强制通过孔以及真空力。搁板的孔和旋转切割器的孔协作以剪切被柱塞压缩的组织。然后在液体冲洗的帮助下，将切碎的组织在真空力下输送到组织收集室。然后可以根据需要进一步处理收集的切碎的组织用于给定的医疗处理或程序。

10. 发明申请

US20110208087A1 Tissue Harvesting, Mincing, and Transport Device 失效
标题翻译：组织收获，挖掘和运输装置
公开(公告)号：US20110208087A1
公开(公告)日：2011-08-25
申请号：US12709738
申请日：2010-02-22
申请人： Michael J. Trezza, II , John A. Hibner , Joseph C. Hueil , Patrick A. Mescher
发明人： Michael J. Trezza, II , John A. Hibner , Joseph C. Hueil , Patrick A. Mescher
IPC分类号： A61B10/02
CPC分类号： A61B17/320016 , A61B10/0275 , A61B10/0283 , A61B2010/0208
摘要： A device comprises a needle, probe, holster, and tissue collection chamber. A motor simultaneously powers a vacuum pump, translates and rotates a cutter, and translates a plunger. The needle includes a piercing tip and an interior shelf that divides the needle into a cutter lumen and lateral lumen. The cutter and shelf include apertures configured to mince a portion of a tissue specimen that has been severed by the cutter and forced through the apertures by compressive force from the plunger as well as vacuum force. The apertures of the shelf and the apertures of the rotating cutter cooperate to shear the tissue being compressed by the plunger. The minced tissue is then transported to the tissue collection chamber under vacuum force with the assistance of a fluid flush. Collected minced tissue may then be further processed as desired for a given medical treatment or procedure.
摘要翻译：一种装置包括针，探针，皮套和组织收集室。马达同时为真空泵供电，平移和旋转切割器，并平移柱塞。针包括穿刺尖端和将针分成切割器腔和侧腔的内部搁架。切割器和搁板包括孔，该孔被构造成切割由切割器切断的组织样本的一部分，并通过来自柱塞的压力强制通过孔以及真空力。搁板的孔和旋转切割器的孔协作以剪切被柱塞压缩的组织。然后在液体冲洗的帮助下，将切碎的组织在真空力下输送到组织收集室。然后可以根据需要进一步处理收集的切碎的组织用于给定的医疗处理或程序。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式