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1. 发明授权

US4973578A Synthetic peptides derived from the alpha-subunit of human lycoprotein hormones 失效
标题翻译：衍生自人类赖氨酸蛋白激素的α-亚基的合成肽
公开(公告)号：US4973578A
公开(公告)日：1990-11-27
申请号：US169375
申请日：1988-03-17
申请人： Robert J. Ryan , Daniel J. McCormick , John C. Morris , M. Cristine Charlesworth
发明人： Robert J. Ryan , Daniel J. McCormick , John C. Morris , M. Cristine Charlesworth
IPC分类号： A61K38/00 , C07K14/59
CPC分类号： C07K14/59 , A61K38/00 , Y10S530/85 , Y10S530/854
摘要： Synthetic peptides corresponding to .alpha.-subunit of human glycoprotein hormone amino acid regions .alpha.31-45, .alpha.21-35, .alpha.26-46 and .alpha.81-92; were found to inhibit binding of 125.sub.I-bTSH to human thyroid. Peptides corresponding to regions .alpha.26-46 and .alpha.31-45 were also found to potently inhibit the stimulation of adenylate cyclase activity by bTSH in a TSH bioassay using FRTL-5 cells and block the action of thyroid stimulating immunoglobulin.
摘要翻译：对应于人类糖蛋白激素氨基酸区域α-31-45，α21-35，α26-46和α81-92的α-亚单位的合成肽; 被发现抑制125I-bTSH与人甲状腺结合。还发现对应于α26-46和α31-45区的肽在使用FRTL-5细胞的TSH生物测定中有效抑制bTSH刺激腺苷酸环化酶活性并阻断甲状腺刺激免疫球蛋白的作用。

2. 发明授权

US5196513A Synthetic peptides derived from the beta-subunit of human thyroid stimulating hormone 失效
标题翻译：衍生自人类甲状腺激素激素的β亚基的合成肽
公开(公告)号：US5196513A
公开(公告)日：1993-03-23
申请号：US736030
申请日：1991-07-25
申请人： Robert J. Ryan , Daniel J. McCormick , John C. Morris
发明人： Robert J. Ryan , Daniel J. McCormick , John C. Morris
IPC分类号： A61K38/00 , C07K14/59 , C07K16/26
CPC分类号： C07K14/59 , C07K16/26 , A61K38/00
摘要： Synthetic peptides corresponding to beta -subunit of human thyroid stimulating hormone amino acid regions beta 1-15, beta 81-95, and beta 101-112, were found to potently inhibit the stimulation of adenylate cyclase activity by bTSH in a TSH bioassay using FRTL5 cells and block the action of thyroid stimulating immunoglobulin.
摘要翻译：对应于人类甲状腺刺激激素氨基酸区域β1-5，β81-95和β101-112的β亚单位的合成肽被发现在使用FRTL5的TSH生物测定中有效地抑制bTSH刺激腺苷酸环化酶活性细胞并阻断甲状腺刺激免疫球蛋白的作用。

3. 发明授权

US08155742B2 Remote communication system with availability indicator for an implantable medical device 有权
标题翻译：具有可植入医疗设备的可用性指示器的远程通信系统
公开(公告)号：US08155742B2
公开(公告)日：2012-04-10
申请号：US11380139
申请日：2006-04-25
申请人： James J. Ball , Robert J. Ryan
发明人： James J. Ball , Robert J. Ryan
IPC分类号： A61N1/08
CPC分类号： A61N1/37282
摘要： A medical information communication system and corresponding methods are described. The system can permit monitoring the performance of an implantable medical device (IMD) implanted within a body of a patient, monitoring the health of the patient, and/or remotely delivering a therapy to the patient through the IMD. The IMD can be capable of bi-directional communication with a clinician. Further, the system can comprise a communication availability indicator to indicate whether the IMD is available for communication.
摘要翻译：描述医疗信息通信系统及相应的方法。该系统可以允许监测植入在患者身体内的可植入医疗装置（IMD）的性能，监测患者的健康，和/或通过IMD远程地向患者传递治疗。 IMD能够与临床医生进行双向通信。此外，系统可以包括用于指示IMD是否可用于通信的通信可用性指示符。

4. 发明授权

US4228050A Conductive molding composition 失效
标题翻译：导电成型组合物
公开(公告)号：US4228050A
公开(公告)日：1980-10-14
申请号：US3363
申请日：1979-01-15
申请人： Carl J. Martin , Marvin J. Voelker , Robert J. Ryan
发明人： Carl J. Martin , Marvin J. Voelker , Robert J. Ryan
IPC分类号： G11B11/06 , C08L27/06 , G11B9/06 , G11B11/00 , G11B11/08 , C08L91/00 , H04N5/76 , H04N5/82
CPC分类号： G11B9/068
摘要： An improved molding composition having a bulk resistivity below about 500 ohm-cm at 900 megahertz for compression molding video discs comprising sufficient conductive carbon black particles to obtain the desired conductivity, from about 1.5 to 4 percent by weight of stabilizers, from about 1 to 3 percent by weight of at least two lubricants, up to 10 percent by weight of plasticizers and processing aids, the remainder being a polyvinylchloride based resin, with the proviso that not more than about 5 percent by weight of liquid additives are present in said molding composition. Video discs molded from said composition have improved dimensional stability.
摘要翻译：一种改进的模制组合物，其具有在900兆赫兹下的体积电阻率低于约500欧姆 - 厘米的压缩模塑视频盘，其包含足够的导电炭黑颗粒以获得所需的导电率，约1.5至4重量％的稳定剂，约1至3 至少两种润滑剂的重量百分比，至多10重量％的增塑剂和加工助剂，其余为聚氯乙烯基树脂，条件是在所述模塑组合物中不超过约5重量％的液体添加剂。由所述组合物模制的视盘具有改进的尺寸稳定性。

5. 发明授权

US4129536A Vinyl chloride based injection molding composition 失效
标题翻译：氯乙烯基注塑组合物
公开(公告)号：US4129536A
公开(公告)日：1978-12-12
申请号：US818280
申请日：1977-07-25
申请人： Carl J. Martin , Robert J. Ryan
发明人： Carl J. Martin , Robert J. Ryan
IPC分类号： C08L27/00 , C08K5/58 , C08L1/00 , C08L27/06 , C08L33/00 , C08L33/02 , C08L33/08 , C08F15/00 , C08F114/02 , G11B3/44
CPC分类号： C08L27/06 , C08L33/08
摘要： A vinyl chloride based injection molding composition comprises a vinyl chloride-propylene copolymer, a mercapto tin stabilizer, an acrylic processing aid and an ester wax lubricant. This composition has excellent flow characteristics and can form molded articles with sub-micron dimensional details and excellent surface characteristics.
摘要翻译：一种基于氯乙烯的注塑组合物包括氯乙烯 - 丙烯共聚物，巯基锡稳定剂，丙烯酸加工助剂和酯蜡润滑剂。该组合物具有优异的流动特性，并且可以形成具有亚微米尺寸细节和优异表面特性的模制品。

6. 发明授权

US5861548A Apparatus and method utilizing signal modulation detection for analyzing the internal pressure of containers 失效
标题翻译：用于分析容器内部压力的信号调制检测装置和方法
公开(公告)号：US5861548A
公开(公告)日：1999-01-19
申请号：US71787
申请日：1998-05-01
申请人： Robert G. Melvin, II , Robert J. Ryan
发明人： Robert G. Melvin, II , Robert J. Ryan
IPC分类号： G01L11/04 , G01M3/24 , G01N29/06 , G01N29/12 , G01N29/34 , G01N29/42 , G01M3/00 , G01L9/10 , G01N29/04
CPC分类号： G01N29/42 , G01L11/04 , G01M3/24 , G01N29/0609 , G01N29/12 , G01N29/346 , G01N29/348 , G01N2291/014 , G01N2291/015 , G01N2291/02872 , G01N2291/2695
摘要： A method for analyzing the internal pressure of a closed container includes inducing vibration in a surface of the container; detecting sound resulting from the vibration; deriving information representing the detecting sound; and determining whether this information corresponds to a predetermined spectral frequency condition and a predetermined spectral amplitude condition. To ensure that the test results are not affected by modulating distortion which may be present in the information, the information is tested for the presence of a modulating distortion, and if so processed to compensate for the effects of this modulating distortion, prior to being tested against the predetermined spectral conditions. Alternatively or in addition, one or both of the upper and lower amplitude limits which define the spectral amplitude condition may be reset periodically to allow for slow changes in manufacturing conditions by accumulating amplitude data from a plurality of containers judged to have an acceptable internal pressure, analyzing this amplitude data to derive an average value and a deviation therefrom, and resetting one or both of the amplitude limits in dependence upon the derived average value and deviation.
摘要翻译：用于分析密闭容器的内部压力的方法包括在容器的表面中引起振动; 检测振动产生的声音; 导出表示检测声音的信息; 以及确定该信息是否对应于预定的频谱频率条件和预定的频谱幅度条件。为了确保测试结果不受信号中可能存在的调制失真的影响，测试信息是否存在调制失真，如果这样进行处理以补偿此调制失真的影响，则在测试之前抵抗预定的光谱条件。或者或另外，定义频谱幅度条件的上限和下限幅度之一或两者可以周期性复位，以允许通过累积来自被判定为具有可接受的内部压力的多个容器的振幅数据来制造条件的缓慢变化，分析该振幅数据以导出平均值及其偏差，并且根据导出的平均值和偏差来重置振幅极限中的一个或两个。

7. 发明授权

US5203919A Method and compositions for stabilizing concrete residues 失效
标题翻译：用于稳定混凝土残留物的方法和组合物
公开(公告)号：US5203919A
公开(公告)日：1993-04-20
申请号：US861152
申请日：1992-03-27
申请人： Gregory S. Bobrowski , Robert J. Ryan
发明人： Gregory S. Bobrowski , Robert J. Ryan
IPC分类号： C04B18/16 , C04B24/00 , C04B24/16 , C04B24/26 , C04B24/42 , C04B28/02
CPC分类号： C04B28/02 , C04B18/16 , C04B24/003 , C04B24/16 , C04B24/2652 , C04B24/42 , C04B2103/20 , Y02W30/95
摘要： Method and compositions for the stabilization (prevention of hardening) of concrete residues in Ready-Mix truck drums.
摘要翻译：混合罐车桶中混凝土残留物的稳定化（防止硬化）的方法和组合物。

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