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1. 发明授权

US4997847A Biologically active compounds 失效
标题翻译：生物活性化合物
公开(公告)号：US4997847A
公开(公告)日：1991-03-05
申请号：US235061
申请日：1988-08-22
申请人： Robert J. Ife , David G. Cooper , Robert A. Slater , Karlheinz Stegmeier , Ernst-Christian Witte
发明人： Robert J. Ife , David G. Cooper , Robert A. Slater , Karlheinz Stegmeier , Ernst-Christian Witte
IPC分类号： A61K31/195 , A61K31/19 , A61K31/34 , A61K31/341 , A61K31/38 , A61K31/381 , A61K31/63 , A61P7/02 , C07C303/36 , C07C311/19 , C07C311/29 , C07D307/64 , C07D333/34
CPC分类号： A61K31/19 , A61K31/34 , A61K31/38 , A61K31/63 , C07D307/64 , C07D333/34
摘要： The invention relates to phenylsulphonamidolkanoic acids which have thromboxane A.sub.2 receptor antagonist activity.

2. 发明授权

US06305235B1 Variable height sensor tree 失效
标题翻译：可变高度传感器树
公开(公告)号：US06305235B1
公开(公告)日：2001-10-23
申请号：US09168607
申请日：1998-10-09
申请人： John D. Geurian , David G. Cooper , Xuong P. Hong
发明人： John D. Geurian , David G. Cooper , Xuong P. Hong
IPC分类号： G01D2100
CPC分类号： G01F23/0007
摘要： A variable position sensing device is provided. The device includes a fixed track attached to a track holder. An adjustable sensor holder is adapted to receive a sensor and is capable of sliding and locking into position on the fixed track. The sensor device has particular applicability and the semiconductor manufacturing industry for setting sensors at different positions in a liquid chemical holding vessel.
摘要翻译：提供了可变位置检测装置。该装置包括固定轨道，该轨道固定在轨道支架上。可调节的传感器支架适于接收传感器并且能够滑动并锁定到固定轨道上的位置。传感器装置具有特别的适用性，以及半导体制造工业，用于在液体化学容器内的不同位置设置传感器。

3. 发明授权

US5338752A Substituted 2-imidazolone derivatives, their preparation and pharmaceutical compositions 失效
标题翻译：取代的2-咪唑啉酮衍生物，其制备方法和药物组合物
公开(公告)号：US5338752A
公开(公告)日：1994-08-16
申请号：US30094
申请日：1993-05-10
申请人： Deirdre M. B. Hickey , David G. Cooper , Albert A. Jaxa-Chamiec
发明人： Deirdre M. B. Hickey , David G. Cooper , Albert A. Jaxa-Chamiec
IPC分类号： A61K31/415 , A61K31/675 , A61P7/02 , A61P9/08 , C07D233/70 , C07D403/06 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/14 , C07F9/6506 , C07D257/04 , C07D233/32 , C07F9/06
CPC分类号： C07D403/06 , C07D233/70 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/14 , C07F9/65061
摘要： ##STR1## Substituted 4,5-diaryl-2-imidazolones of structure (I), in which each group AR is the same or different and is optionally substituted phenyl or optionally substituted heteroaryl; R
1 is hydrogen, alkyl, optionally substituted phenyl or optionally substituted heteroaryl; n is 4 to 12; and X is 5-tetrazolyl, SO
3 H, P(O)(OR)
2 , P(O)(OH)
2 or P(O)(R)(OR) in which R is hydrogen acceptable salt thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, inter alia, in the treatment of cardiovascular disorders.
摘要翻译： PCT No.PCT / GB91 / 01543 Sec。 371日期：1993年5月10日 102（e）日期1993年5月10日PCT 1991年9月10日PCT PCT。出版物WO92 / 04331 （I）结构（I）的取代的4,5-二芳基-2-咪唑啉酮，其中每个基团AR相同或不同，并且是任选取代的苯基或任选取代的杂芳基; R 1是氢，烷基，任选取代的苯基或任选取代的杂芳基; n为4〜12; 和X是其中R是其氢可接受的盐的5-四唑基，SO 3 H，P（O）（OR）2，P（O）（OH）2或P（O）（R）（OR），含有它们的药物组合物及其在治疗中的用途，特别是治疗心血管疾病。

4. 发明授权

US4771058A 3,4-diamino-1,2,5-thiadiazole-1-oxides having histamine H.sub.1 -antagonist activity 失效
标题翻译：具有组胺H1-拮抗剂活性的3,4-二氨基-1,2,5-噻二唑-1-氧化物
公开(公告)号：US4771058A
公开(公告)日：1988-09-13
申请号：US873009
申请日：1986-06-11
申请人： David G. Cooper , George S. Sach
发明人： David G. Cooper , George S. Sach
IPC分类号： C07D417/12 , C07D417/14 , A61K31/44
CPC分类号： C07D417/12 , C07D417/14
摘要： The invention relates to a class of 3,4-diamino-1,2,5-thiadiazole-1-oxides which have histamine H.sub.1 -antagonist activity. A preferred compound of the invention is 3-[3-(5-bromo-3-methylpyrid-2-ylamino)-propylamino]-4-amino-1,2,5-thiadiazole-1-oxide.
摘要翻译：本发明涉及具有组胺H1-拮抗剂活性的一类3,4-二氨基-1,2,5-噻二唑-1-氧化物。本发明优选的化合物是3- [3-（5-溴-3-甲基吡啶-2-基氨基） - 丙氨基] -4-氨基-1,2,5-噻二唑-1-氧化物。

5. 发明授权

US4432887A De-emulsification agents of microbiological origin 失效
标题翻译：微生物来源的脱乳化剂
公开(公告)号：US4432887A
公开(公告)日：1984-02-21
申请号：US298734
申请日：1981-09-02
申请人： James E. Zajic , David G. Cooper
发明人： James E. Zajic , David G. Cooper
IPC分类号： B01D17/04 , C02F3/34 , C10G33/00 , C12P1/04 , C12P1/06 , C02C5/02
CPC分类号： C12P1/04 , B01D17/047 , C02F3/34 , C10G33/00 , C12P1/06
摘要： There is provided a process for breaking or at least destabilizing oil-in-water emulsions and water-in-oil emulsions, which comprises adding to the emulsion a broth or portion of a broth resulting from the culture therein of specifically selected bacterial microorganisms of the genus Nocardia, Rhodococcus, Arthrobacter, Corynebacterium or Mycobacterium. In particular, the microorganisms, Nocardia amarae, Rhodococcus aurantiacus and Rhodococcus rubropertinctus have been found to yield broths, following cultivation, having exceptionally good properties as de-emulsifying agents.
摘要翻译：提供了一种用于破坏或至少不稳定水包油乳液和油包水乳液的方法，其包括向其中加入肉汤或其中培养的肉汤的部分特定选择的细菌微生物诺卡氏菌属，红球菌属，节杆菌属，棒状杆菌属或分枝杆菌属。特别地，已经发现微生物，诺卡氏菌，红球菌和红球菌，在培养后产生肉汤，具有特别好的脱乳剂特性。

6. 外观设计

USD388804S Electronic camera 失效
公开(公告)号：USD388804S
公开(公告)日：1998-01-06
申请号：US59517
申请日：1996-09-12
申请人： Samuel F. Swayze , David G. Cooper , Kevin R. Young
设计人： Samuel F. Swayze , David G. Cooper , Kevin R. Young

7. 发明授权

US5272929A Transmission shaft carrying at least two gears 失效
标题翻译：传动轴承载至少两个齿轮
公开(公告)号：US5272929A
公开(公告)日：1993-12-28
申请号：US733799
申请日：1991-07-22
申请人： Melvern W. Fletcher , Trevor Pitchford , David G. Cooper
发明人： Melvern W. Fletcher , Trevor Pitchford , David G. Cooper
IPC分类号： B23P15/14 , F16D1/06 , F16D1/08 , F16H3/02 , F16H55/17 , F16H57/00 , F16H3/08
CPC分类号： F16H57/0025 , F16D1/0876 , F16D2001/103 , Y10T74/19167 , Y10T74/19233
摘要： A gear shaft assembly (42) is provided including a shaft (5) having a first set of gear teeth (6) formed integrally in a second portion (51) thereof and extensions of said teeth extend axially over an adjacent reduced diameter second portion (50) for receivably mounting a second gear (7) for rotation with the shaft.

8. 发明授权

US5029953A Ultraviolet optical isolator utilizing the KDP-isomorphs 失效
标题翻译：紫外光隔离器利用KDP同构物
公开(公告)号：US5029953A
公开(公告)日：1991-07-09
申请号：US597847
申请日：1990-10-17
申请人： James L. Dexter , John F. Reintjes, Jr. , Joseph E. Landry , David G. Cooper
发明人： James L. Dexter , John F. Reintjes, Jr. , Joseph E. Landry , David G. Cooper
IPC分类号： G02F1/09
CPC分类号： G02F1/093 , Y10S372/703
摘要： An ultraviolet optical isolater which utilizes a KDP-isomorph crystal as optical element is disclosed. In a preferred embodiment, the ultraviolet optical isolator comprises: an input polarizer for linearly polrizing an input beam of ultraviolet light in a first plane of polarization; means for rotating the plane of polarization of the linarly polarized ultraviolet light from the input polarizer by substantially 45 degrees in a first direction; a Faraday rotator including an optical element made of a KDP-isomorph crystal in which the plane of polarization of the rotated linearly polarized ultraviolet light from the rotating means is rotated about an optical axis of the optical element, a plurality of permanent magnets sequentially coupled together with altnerating polarities for developing a magnetic field along the optical axis of the optical element in order to cause the optical element to rotate the plane of polarization of the rotated linearly polarized ultraviolet light from the rotating means by substantially another 45 degrees in the first direction to a second plane of polarization substantially orthogonal to the first plane of polarization, and means for moving the optical element so that the optical element is always enclosed by the plurality of permanent magnets; and an output polarizer for outputting the ultraviolet light in the second plane of polarization.
摘要翻译：公开了一种利用KDP同构晶体作为光学元件的紫外线光隔离器。在优选实施例中，紫外光隔离器包括：输入偏振器，用于在第一极化平面中线性地刺激输入紫外光束; 用于使来自所述输入偏振器的所述线偏振紫外光的偏振平面在第一方向上旋转45度的装置; 包括由KDP同构晶体制成的光学元件的法拉第旋转器，其中来自旋转装置的旋转的线偏振紫外光的偏振平面围绕光学元件的光轴旋转，多个永久磁体顺序耦合在一起具有用于沿光学元件的光轴显影磁场的等级极性，以便使光学元件将旋转的线性偏振紫外光的偏振平面从旋转装置沿第一方向旋转大约另一个45度，直到基本上与第一偏振平面正交的第二极化平面和用于移动光学元件使得光学元件总是被多个永磁体包围的装置; 以及用于输出第二偏振平面中的紫外光的输出偏振器。

9. 发明授权

US4902698A Benzenesulphonamidopyridyl compounds which are useful as thromboxane A.sub. 2 失效
标题翻译：可用作血栓烷A2拮抗剂的苯磺酰胺基吡啶基化合物
公开(公告)号：US4902698A
公开(公告)日：1990-02-20
申请号：US178663
申请日：1988-04-07
申请人： David G. Cooper
发明人： David G. Cooper
IPC分类号： A61K31/44 , A61K31/4418 , A61P7/02 , A61P9/08 , A61P9/10 , C07D213/70 , C07D213/76
CPC分类号： C07D213/70 , C07D213/76
摘要： The invention provides a class of alkanoic acids substituted with a benzenesulphonamidopyridyl group. The compounds have activity as thromboxane A.sub.2 -antagonists.

10. 发明授权

US4868515A Narrow-bandwidth unstable laser resonator 失效
标题翻译：窄带宽不稳定激光谐振器
公开(公告)号：US4868515A
公开(公告)日：1989-09-19
申请号：US260847
申请日：1988-10-21
申请人： John F. Reintjes , David G. Cooper
发明人： John F. Reintjes , David G. Cooper
IPC分类号： H01S3/081
CPC分类号： H01S3/0811
摘要： A narrow-bandwidth, unstable laser resonator comprising: an output sectionncluding a laser gain medium for generating and amplifying light, a first reflective element for reflecting and collimating light from the gain medium back through the gain medium, and a second reflective element having a hole therein, the second reflective element being responsive to the collimated light passed through the gain medium for reflecting most of the collimated light out of the unstable laser resonator as an output beam and for passing the remaining portion of the collimated light through the hole therein as a residual beam; and a feedback ring including an optical path, a beam splitter for passing a first portion of the residual beam into the optical path in a first direction, a frequency-narrowing element disposed at a position in the optical path where the first portion of the residual beam is collimated, the frequency-narrowing element being operative to narrow the frequency bandwidth of the first portion of the residual beam to produce a narrow-bandwidth collimated beam, a lens disposed in the optical path for focusing the narrow-bandwidth collimated beam to cause light from that beam to be reflected from the beam splitter and passed through the hole in the second reflective element as a narrow-bandwidth convergent beam before the narrow-bandwidth convergent beam before the narrow-bandwidth convergent beam is amplified by the gain medium.
摘要翻译：一种窄带宽不稳定的激光谐振器，包括：包括用于产生和放大光的激光增益介质的输出部分，用于通过增益介质反射和准直来自增益介质的光的第一反射元件，以及具有孔中，第二反射元件响应于准直光通过增益介质，用于将来自不稳定激光谐振器的大部分准直光作为输出光束反射，并将准直光的剩余部分通过其中的孔通过其中，作为剩余光束; 以及包括光路的反馈环，用于使剩余光束的第一部分沿第一方向通过光束的分束器，设置在光路中的残留物的第一部分处的位置处的频率变窄元件，光束被准直，所述频率变窄元件可操作以使残余光束的第一部分的频率带宽变窄以产生窄带宽准直光束，设置在光路中用于聚焦窄带准直光束的透镜导致来自该光束的光从分束器反射，并且在窄带宽收敛光束之前通过增益介质放大窄带收敛光束之前，作为窄带宽收敛光束穿过第二反射元件中的孔。

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