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    • 3. 发明申请
    • SYSTEM FOR THE DETECTION OF CARDIAC EVENTS
    • 检测心脏事件的系统
    • US20080064973A1
    • 2008-03-13
    • US11930027
    • 2007-10-30
    • David FischellTim FischellJonathan HarwoodRobert FischellSteven Johnson
    • David FischellTim FischellJonathan HarwoodRobert FischellSteven Johnson
    • A61B5/0402
    • A61B5/02455A61B5/0031A61B5/04012A61B5/0422A61B5/0452A61B5/0456A61B5/0468A61B5/0472A61B5/746A61B5/7465A61B2560/0209
    • Disclosed is a system for the detection of cardiac events (a guardian system) that includes an implanted device called a cardiosaver, a physician's programmer and an external alarm system. The system is designed to provide early detection of cardiac events such as acute myocardial infarction or exercise induced myocardial ischemia caused by an increased heart rate or exertion. The system can also alert the patient with a less urgent alarm if a heart arrhythmia is detected. Using one or more detection algorithms, the cardiosaver can detect a change in the patient's electrogram that is indicative of a cardiac event within five minutes after it occurs and then automatically warn the patient that the event is occurring. To provide this warning, the guardian system includes an internal alarm sub-system (internal alarm means) within the cardiosaver and/or an external alarm system (external alarm means). If the guardian system is put into a pacemaker, the algorithm can utilize a different analysis of the electrogram depending on whether or not the pacemaker is actually pacing the heart.
    • 公开了一种用于检测心脏事件(监护系统)的系统,其包括称为心脏切除器的植入装置,医师编程器和外部警报系统。 该系统旨在提供心脏事件的早期检测,例如由心率增加或运动引起的急性心肌梗死或运动诱发的心肌缺血。 如果检测到心律失常,该系统还可以警告患者不太紧急的警报。 使用一个或多个检测算法,心脏扫描器可以检测患者的电描记图中的变化,其指示在发生后五分钟内的心脏事件,然后自动向患者发出事件发生。 为了提供此警告,监护系统包括在心脏保护器内和/或外部报警系统(外部报警装置)内的内部报警子系统(内部报警装置)。 如果将监护人系统放入心脏起搏器,该算法可以根据起搏器是否实际起搏心脏,对电图进行不同的分析。
    • 6. 发明申请
    • Electrogram signal filtering in systems for detecting ischemia
    • 用于检测缺血的系统中的电图信号滤波
    • US20050137483A1
    • 2005-06-23
    • US10741141
    • 2003-12-22
    • Robert FischellDavid FischellTim Fischell
    • Robert FischellDavid FischellTim Fischell
    • A61B5/04A61B5/0402A61B5/0452A61N1/04A61N1/365A61N1/37
    • A61B5/0452A61B5/04012A61N1/3702
    • The present invention is a system that utilizes optimized high pass or band pass filtering to provide accurate detection of changes in the ST segment of an electrogram as detected by an implanted cardiosaver system, which ST segment changes are indicative of coronary ischemia. To accurately detect changes in the ST segment of the electrogram, the cardiosaver system uses either analog or digital high pass filtering having an electrogram voltage reduction of 6 dB at some frequency between 0.05 Hz and 1.0 Hz with less than 6 dB of attenuation at frequencies above 1.0 Hz. and more than 6 dB of attenuation for frequencies below 0.05 Hz. The optimized filter would include attenuation of electric power generation frequencies of either 50 Hz or 60 Hz to reduce electromagnetic interference. The system also includes both implanted and external portions that provide a patient alarm if coronary ischemia is sensed.
    • 本发明是一种利用优化的高通或带通滤波来提供由植入式心血管系统检测到的电描记图ST段变化的精确检测的系统,其中ST段改变指示冠状动脉缺血。 为了准确地检测电描记图ST段的变化,心脏扫描器系统使用模拟或数字高通滤波,其频率在0.05Hz至1.0Hz之间的某一频率处具有6dB的电压降,而在上述频率处具有小于6dB的衰减 1.0 Hz。 对于0.05Hz以下的频率,衰减超过6dB。 优化的滤波器将包括50Hz或60Hz的发电频率的衰减以减少电磁干扰。 该系统还包括植入和外部部分,如果感测到冠状动脉缺血则提供患者报警。
    • 9. 发明申请
    • Means and method for the accurate placement of a stent at the ostium of an artery
    • 支架在动脉口的准确放置的方法和方法
    • US20080082155A1
    • 2008-04-03
    • US11975196
    • 2007-10-18
    • Robert FischellTim FischellDavid FischellMark Zyzelewski
    • Robert FischellTim FischellDavid FischellMark Zyzelewski
    • A61F2/06
    • A61F2/95A61F2002/821A61F2250/0098
    • Disclosed is an ostial stent positioner that has the form of a wire for most of its length and having a short cylinder with a longitudinal slit and expandable legs situated at the positioner's distal end. The slit cylinder with its attached wire acts as an introducer sheath to introduce a stent delivery system with a stent into the artery that is to be stented. A second aspect of the present invention is a method for accurately placing a stent at the ostium of an artery that would have an ostial stenosis. Examples of such arteries that have ostial stenoses are the right and left main coronary arteries, a saphenous vein graft as used in coronary bypass surgery and the renal arteries. Also disclosed are designs for the slit cylinder that provides a variable diameter so as to fit snugly within guiding catheters having different inside diameters.
    • 公开了一种口腔支架定位器,其具有大部分长度的线的形式,并且具有短圆柱体,其具有位于定位器的远端处的纵向狭缝和可扩展腿。 具有连接线的狭缝圆柱体用作导引鞘,以将具有支架的支架输送系统引入到要被固定的动脉中。 本发明的第二方面是一种将支架精确地放置在具有口腔狭窄的动脉的口处的方法。 具有口腔狭窄的这种动脉的实例是右冠状动脉和左主动脉冠状动脉,用于冠状动脉旁路手术的隐静脉移植物和肾动脉。 还公开了用于狭缝筒的设计,其提供可变直径,以便紧密地配合在具有不同内径的引导导管内。