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1. 发明授权

US07074186B2 Transmit based axial whitening 有权
标题翻译：基于透射的轴向美白
公开(公告)号：US07074186B2
公开(公告)日：2006-07-11
申请号：US10668915
申请日：2003-09-23
申请人： Rickard C. Loftman , Karen E. Morgan , Erkan Mumcuoglu , Kutay F. Ustuner , Zoran Banjanin
发明人： Rickard C. Loftman , Karen E. Morgan , Erkan Mumcuoglu , Kutay F. Ustuner , Zoran Banjanin
IPC分类号： A61B8/00 , A61B8/12 , A61B8/14
CPC分类号： G01S15/895 , G01S7/52026 , G01S7/52046
摘要： Transmit based axial whitening is provided. Ultrasonic waveforms to be transmitted are designed to provide for wideband imaging characteristics prior to detection. Rather than transmitting a waveform having a spectral magnitude as white or flat as possible, waveforms with adjusted spectral content, such as spectrally bi-modal waveforms are generated in order to compensate for subsequent effects. Prior to detection, a more wideband or whiter signal response is provided in response to the transmitted waveform. Any of various alterations of the transmit waveform, such as asymmetric, spectrally bi-modal or other characteristics in anticipation of a system transfer function or physical phenomena through which the signal passes electronically or acoustically to result in a wideband or white spectral magnitude and generally linear spectral phase is used. The transmit waveform is altered to improve the imaging characteristics of the downstream processing.
摘要翻译：提供基于发射的轴向增白。要发射的超声波形被设计成在检测之前提供宽带成像特性。不会发送具有尽可能白色或平坦的光谱幅度的波形，而是产生具有调整的光谱含量（诸如光谱双模态波形）的波形，以便补偿随后的效果。在检测之前，响应于传输的波形提供更宽带或更白的信号响应。发射波形的各种改变中的任何一种，例如在预期系统传递函数或物理现象的情况下的不对称，光谱双模式或其他特性，信号通过该物理现象通过电子或声学通过以产生宽带或白色光谱幅度并且通常为线性使用光谱相位。改变发射波形以改善下游处理的成像特性。

2. 发明申请

US20090306512A1 Coherent Image Formation for Dynamic Transmit Beamformation 有权
标题翻译：用于动态发射信号的相干图像形成
公开(公告)号：US20090306512A1
公开(公告)日：2009-12-10
申请号：US12477783
申请日：2009-06-03
申请人： Rickard C. Loftman , Kutay F. Ustuner , Charles E. Bradley
发明人： Rickard C. Loftman , Kutay F. Ustuner , Charles E. Bradley
IPC分类号： A61B8/14
CPC分类号： G01S7/52046 , G01S7/5202 , G01S7/5209 , G01S7/52095 , G10K11/346
摘要： Retrospective dynamic transmit beamformation is provided in medical ultrasound imaging. Using parallel receive beamformation, sets of data representing locations in at least a common field of view are obtained, each set in response to a transmit with a spatially distinct phase front. The common field of view receive data are time aligned and amplitude weighted for retrospective transmit focusing and retrospective transmit apodization, respectively. A time offset, such as of a cycle or more in some cases, is applied to the receive data for retrospective transmit focusing. The offset is selected to emulate shifting the transmit delay profile to be tangentially intersecting with the dynamic receive delay profile for each location which is the desired transmit delay profile. A weight is applied to the receive data for retrospective transmit apodization. The weight is selected based on the desired transmit apodization profile. The offset and weighted data representing a same location from different transmit events is coherently combined. The number of sets of data offset, weighted and combined may vary as a function of depth for dynamic transmit beamformation.
摘要翻译：在医学超声成像中提供回溯动态发射波束形成。使用并行接收波束形成，获得在至少公共视场中表示位置的数据集合，每个集合响应于具有空间上不同相位前沿的传输。对于追溯发射聚焦和追溯发射变迹，共同视野接收数据分别对时间对齐和幅度加权。在一些情况下，例如周期或更多的时间偏移被应用于用于追溯发射聚焦的接收数据。选择该偏移以模拟将发射延迟分布移动为与期望的发射延迟分布的每个位置的动态接收延迟分布切线相交。将加权应用于接收数据用于追溯发射变迹。基于所需的发射变迹轮廓来选择权重。表示来自不同发送事件的相同位置的偏移和加权数据被一致地组合。数据偏移量，加权和组合的数量可以随动态传输波束形成的深度而变化。

3. 发明授权

US08241216B2 Coherent image formation for dynamic transmit beamformation 有权
标题翻译：用于动态发射波束形成的相干图像形成
公开(公告)号：US08241216B2
公开(公告)日：2012-08-14
申请号：US12477783
申请日：2009-06-03
申请人： Rickard C. Loftman , Kutay F. Ustuner , Charles E. Bradley
发明人： Rickard C. Loftman , Kutay F. Ustuner , Charles E. Bradley
IPC分类号： A61B8/00
CPC分类号： G01S7/52046 , G01S7/5202 , G01S7/5209 , G01S7/52095 , G10K11/346
摘要： Retrospective dynamic transmit beamformation is provided in medical ultrasound imaging. Using parallel receive beamformation, sets of data representing locations in at least a common field of view are obtained, each set in response to a transmit with a spatially distinct phase front. The common field of view receive data are time aligned and amplitude weighted for retrospective transmit focusing and retrospective transmit apodization, respectively. A time offset, such as of a cycle or more in some cases, is applied to the receive data for retrospective transmit focusing. The offset is selected to emulate shifting the transmit delay profile to be tangentially intersecting with the dynamic receive delay profile for each location which is the desired transmit delay profile. A weight is applied to the receive data for retrospective transmit apodization. The weight is selected based on the desired transmit apodization profile. The offset and weighted data representing a same location from different transmit events is coherently combined. The number of sets of data offset, weighted and combined may vary as a function of depth for dynamic transmit beamformation.
摘要翻译：在医学超声成像中提供回溯动态发射波束形成。使用并行接收波束形成，获得在至少公共视场中表示位置的数据集合，每个集合响应于具有空间上不同相位前沿的传输。对于追溯发射聚焦和追溯发射变迹，共同视野接收数据分别对时间对齐和幅度加权。在一些情况下，例如周期或更多的时间偏移被应用于用于追溯发射聚焦的接收数据。选择该偏移以模拟将发射延迟分布移动为与期望的发射延迟分布的每个位置的动态接收延迟分布切线相交。将加权应用于接收数据用于追溯发射变迹。基于所需的发射变迹轮廓来选择权重。表示来自不同发送事件的相同位置的偏移和加权数据被一致地组合。数据偏移量，加权和组合的数量可以随动态传输波束形成的深度而变化。

4. 发明授权

US08690781B2 Coherent image formation for dynamic transmit beamformation 有权
标题翻译：用于动态发射波束形成的相干图像形成
公开(公告)号：US08690781B2
公开(公告)日：2014-04-08
申请号：US13538744
申请日：2012-06-29
申请人： Rickard C. Loftman , Kutay F. Ustuner , Charles E. Bradley
发明人： Rickard C. Loftman , Kutay F. Ustuner , Charles E. Bradley
IPC分类号： A61B8/00
CPC分类号： G01S7/52046 , G01S7/5202 , G01S7/5209 , G01S7/52095 , G10K11/346
摘要： Using parallel receive beamformation, sets of data representing locations in at least a common field of view are obtained, each set in response to a transmit with a spatially distinct phase front. The common field of view receive data are time aligned and amplitude weighted for retrospective transmit focusing and retrospective transmit apodization, respectively. A time offset is applied to the receive data for retrospective transmit focusing. The offset is selected to emulate shifting the transmit delay profile to be tangentially intersecting with the dynamic receive delay profile for each location which is the desired transmit delay profile. A weight is applied to the receive data for retrospective transmit apodization. The offset and weighted data representing a same location from different transmit events is coherently combined. The number of sets of data offset, weighted and combined may vary as a function of depth for dynamic transmit beamformation.
摘要翻译：使用并行接收波束形成，获得在至少公共视场中表示位置的数据集合，每个集合响应于具有空间上不同相位前沿的传输。对于追溯发射聚焦和追溯发射变迹，共同视野接收数据分别对时间对齐和幅度加权。时间偏移被应用于用于追溯发射聚焦的接收数据。选择该偏移以模拟将发射延迟分布移动为与期望的发射延迟分布的每个位置的动态接收延迟分布切线相交。将加权应用于接收数据用于追溯发射变迹。表示来自不同发送事件的相同位置的偏移和加权数据被一致地组合。数据偏移量，加权和组合的数量可以随动态传输波束形成的深度而变化。

5. 发明申请

US20120283568A1 Coherent Image Formation for Dynamic Transmit Beamformation 有权
标题翻译：用于动态发射信号的相干图像形成
公开(公告)号：US20120283568A1
公开(公告)日：2012-11-08
申请号：US13538744
申请日：2012-06-29
申请人： Rickard C. Loftman , Kutay F. Ustuner , Charles E. Bradley
发明人： Rickard C. Loftman , Kutay F. Ustuner , Charles E. Bradley
IPC分类号： A61B8/14
CPC分类号： G01S7/52046 , G01S7/5202 , G01S7/5209 , G01S7/52095 , G10K11/346
摘要： Using parallel receive beamformation, sets of data representing locations in at least a common field of view are obtained, each set in response to a transmit with a spatially distinct phase front. The common field of view receive data are time aligned and amplitude weighted for retrospective transmit focusing and retrospective transmit apodization, respectively. A time offset is applied to the receive data for retrospective transmit focusing. The offset is selected to emulate shifting the transmit delay profile to be tangentially intersecting with the dynamic receive delay profile for each location which is the desired transmit delay profile. A weight is applied to the receive data for retrospective transmit apodization. The offset and weighted data representing a same location from different transmit events is coherently combined. The number of sets of data offset, weighted and combined may vary as a function of depth for dynamic transmit beamformation.
摘要翻译：使用并行接收波束形成，获得在至少公共视场中表示位置的数据集合，每个集合响应于具有空间上不同相位前沿的传输。对于追溯发射聚焦和追溯发射变迹，共同视野接收数据分别对时间对齐和幅度加权。时间偏移被应用于用于追溯发射聚焦的接收数据。选择该偏移以模拟将发射延迟分布移动为与期望的发射延迟分布的每个位置的动态接收延迟分布切线相交。将加权应用于接收数据用于追溯发射变迹。表示来自不同发送事件的相同位置的偏移和加权数据被一致地组合。数据偏移量，加权和组合的数量可以随动态传输波束形成的深度而变化。

6. 发明授权

US06679844B2 Automatic gain compensation for multiple mode or contrast agent imaging 有权
标题翻译：多模式或造影剂成像的自动增益补偿
公开(公告)号：US06679844B2
公开(公告)日：2004-01-20
申请号：US10176274
申请日：2002-06-20
申请人： Rickard C. Loftman , Ismayil M. Guracar , Patrick J. Phillips , Zafer Zamboglu
发明人： Rickard C. Loftman , Ismayil M. Guracar , Patrick J. Phillips , Zafer Zamboglu
IPC分类号： A61B800
CPC分类号： G01S7/52033 , A61B8/481 , G01S7/52026
摘要： The gain for multiple mode imaging and/or contrast agent imaging is automatically adjusted. The gain algorithm separately determines gain parameters for two different types of imaging, such as tissue and contrast agent imaging. The gain based on the contrast agent image may be optimized to provide maximum sensitivity, such as by mapping noise values measured prior to injection of contrast agent to low values within the dynamic range or somewhat below the display dynamic range. The automatic gain based on the contrast agent image may be free of variance calculations. One of the two gain parameters is selected as the system gain, or the two gain parameters are combined to form the system gain. The presence of contrast agents within the image may be determined, and different gain parameters used based on the presence or absence of contrast agents. Various ones or combinations of the gain adjustments summarized above may be used.
摘要翻译：自动调整多模式成像和/或造影剂成像的增益。增益算法分别确定两种不同类型成像的增益参数，如组织和造影剂成像。基于造影剂图像的增益可以被优化以提供最大灵敏度，例如通过将在造影剂注射之前测量的噪声值映射到在动态范围内或稍低于显示动态范围的低值。基于造影剂图像的自动增益可以没有方差计算。选择两个增益参数之一作为系统增益，或者将两个增益参数组合以形成系统增益。可以确定图像内的造影剂的存在，并且基于造影剂的存在或不存在使用不同的增益参数。可以使用上面概述的各种增益调整或组合。

7. 发明授权

US07887484B2 Automatic velocity scale identification for medical diagnostic ultrasound 有权
标题翻译：医用诊断超声波自动速度刻度识别
公开(公告)号：US07887484B2
公开(公告)日：2011-02-15
申请号：US11202676
申请日：2005-08-12
申请人： Seshadri Srinivasan , Bhaskar Ramamurthy , Ismayil M. Guracar , Patrick J. Phillips , Rickard C. Loftman
发明人： Seshadri Srinivasan , Bhaskar Ramamurthy , Ismayil M. Guracar , Patrick J. Phillips , Rickard C. Loftman
IPC分类号： A61B8/00
CPC分类号： A61B8/06 , A61B8/08 , A61B8/488 , G01S7/5205 , G01S7/52058 , G01S15/584
摘要： Velocity scale is automatically determined for ultrasound imaging. Receive signals corresponding to different pulse repetition intervals are used to estimate velocities. The different velocities are used to determine the velocity scale. For example, the different pulse repetition intervals are obtained by selecting different sets of signals from a group of signals for a scan line. As another example, the different pulse repetition intervals are obtained by transmitting for a scan line with changing, such as increasing, pulse repetition intervals. The lower pulse repetition interval of a pair of intervals associated with a sign change in the phase is used for the velocity scale. In yet another example, at least two demodulation frequencies are used for a broadband transmit in at least two sets, each set with a different pulse repetition interval. Velocities are estimated for a greater number of pulse repetition intervals than transmitted using the broadband pulses.
摘要翻译：自动确定超声波成像的速度刻度。接收与不同脉冲重复间隔对应的信号用于估算速度。不同的速度用于确定速度刻度。例如，通过从扫描线的一组信号中选择不同的信号组来获得不同的脉冲重复间隔。作为另一示例，通过用改变的脉冲重复间隔等增加扫描线来发送不同的脉冲重复间隔。与相位中的符号变化相关联的一对间隔的较低脉冲重复间隔用于速度刻度。在另一个示例中，至少两个解调频率用于至少两组中的宽带传输，每组具有不同的脉冲重复间隔。对于使用宽带脉冲传输的脉冲重复间隔的数量，估计速度。

8. 发明授权

US06589182B1 Medical diagnostic ultrasound catheter with first and second tip portions 有权
标题翻译：具有第一和第二末端部分的医疗诊断超声导管
公开(公告)号：US06589182B1
公开(公告)日：2003-07-08
申请号：US09781694
申请日：2001-02-12
申请人： Rickard C. Loftman , Randall L. Schlesinger , John I. Jackson , Lex J. Garbini , Douglas B. Dull
发明人： Rickard C. Loftman , Randall L. Schlesinger , John I. Jackson , Lex J. Garbini , Douglas B. Dull
IPC分类号： A61B800
CPC分类号： A61B8/4281 , A61B8/12 , A61B8/4483
摘要： The preferred embodiments described herein provide a medical diagnostic ultrasound catheter with a tip portion carrying an ultrasound transducer. The tip portion comprises a first portion that is in the acoustic path of the ultrasound transducer, and a second portion that is outside the acoustic path of the ultrasound transducer. The first and second portions comprise different acoustic and mechanical properties. For example, the mechanical properties of the second portion can give the catheter tip sufficient durability to withstand normal use without bowing, while the acoustic properties of the first portion can give the catheter tip desired acoustic properties. This may be especially important for small diameter catheters (e.g., maximum cross-sectional dimensions less than or equal to about 10 French or 8 French) where the stiffness of the catheter tip is reduced.
摘要翻译：本文所述的优选实施例提供具有携带超声换能器的尖端部分的医疗诊断超声导管。尖端部分包括在超声波换能器的声学路径中的第一部分和位于超声换能器的声路之外的第二部分。第一和第二部分包括不同的声学和机械特性。例如，第二部分的机械特性可以使导管尖端具有足够的耐久性以经受正常使用而不会弯曲，而第一部分的声学特性可使导管尖端具有预期的声学特性。这对于导管尖端的刚度减小的小直径导管（例如，小于或等于约10 French或8 French的最大横截面尺寸）可能是特别重要的。

9. 发明授权

US07534210B2 Methods for adaptively varying gain during ultrasound agent quantification 有权
标题翻译：在超声波定量中自适应变化增益的方法
公开(公告)号：US07534210B2
公开(公告)日：2009-05-19
申请号：US10770724
申请日：2004-02-03
申请人： James E. Chomas , Rickard C. Loftman , Constantine Simopoulos
发明人： James E. Chomas , Rickard C. Loftman , Constantine Simopoulos
IPC分类号： A61B8/00
CPC分类号： A61B8/481 , G01S7/52033 , G01S7/52041 , G01S7/5205
摘要： Methods are provided for automatic setting of parameters for contrast agent quantification. Various processes may improve quantification. For example, for consistency in contrast agent quantification, a gain or other setting of an ultrasound system is automatically determined in response to destruction of the contrast agent or at the initiation of the contrast agent quantification procedure. Automatic setting of an adaptive gain provides equalized image intensity for each repetition of a contrast agent quantification procedure based on a same triggering event, the destruction of contrast agent. By synchronizing the adaptive setting algorithms with contrast agent destruction, similar base line information is provided for each iteration of a contrast agent quantification procedure. As another example, the contrast agent gain setting treats acoustic signals representing tissue or other non-contrast agent structure as noise, mapping the tissue values to a substantially constant low value within the dynamic range. As yet another example, by segmenting out blood pools or other areas of contrast agent likely to have contrast agents even after destruction, the resulting gain is more likely sensitive to the detection of perfused contrast agents.
摘要翻译：提供了用于自动设置造影剂定量参数的方法。各种过程可以提高定量。例如，为了对比剂定量的一致性，响应于造影剂的破坏或在造影剂定量程序开始时自动确定超声系统的增益或其他设置。自适应增益的自动设置为每次重复造影剂定量过程提供均衡的图像强度，该对比剂定量过程基于相同的触发事件，破坏造影剂。通过使自适应设置算法与造影剂破坏同步，为造影剂定量过程的每次迭代提供类似的基线信息。作为另一示例，造影剂增益设置将表示组织或其他非造影剂结构的声学信号视为噪声，将组织值映射到动态范围内的基本上恒定的低值。作为另一个例子，即使在破坏后，通过分割血液池或可能具有造影剂的造影剂的其它区域，所得到的增益更可能对灌注的造影剂的检测敏感。

10. 发明授权

US06790181B2 Overlapped scanning for multi-directional compounding of ultrasound images 有权
公开(公告)号：US06790181B2
公开(公告)日：2004-09-14
申请号：US10243453
申请日：2002-09-13
申请人： Anming He Cai , Rickard C. Loftman
发明人： Anming He Cai , Rickard C. Loftman
IPC分类号： A61B800
CPC分类号： G01S7/52085 , G01S7/52034 , G01S7/5206 , G01S7/5209 , G01S7/52095 , G01S15/8952 , G01S15/8995
摘要： An image formed from compounded frames of ultrasound data acquired with different steering angles is displayed. Each component frame is associated with a scan of the entire displayed region. A majority of scan lines for each component frame are pointed in one direction or the same relative direction, and a minority of the scan lines are steered at different angles within each component frame to scan the rest of the display region, but with a different steering angle for the majority of scan lines of each of the component frames. As a result, the benefits of spatial compounding component frames associated with different steering angles are provided without having to apply filtering to reduce line artifacts.

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