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    • 2. 发明授权
    • Method for passively determining the application of a sample fluid on an
analyte strip
    • 用于被动地确定样品流体在分析物条上的应用的方法
    • US6150124A
    • 2000-11-21
    • US315700
    • 1999-05-20
    • Richard Riedel
    • Richard Riedel
    • C12Q1/54G01N21/86C12Q1/00
    • G01N21/8483C12Q1/54Y10S435/97
    • The present invention relates to a method for passively determining the application of a sample fluid on an analyte strip using measurement of ambient light passing through the strip. Sample fluid, such as whole blood, is applied to a reagent matrix and the amount of ambient light transmitted through the matrix is periodically measured both before and after application of the sample fluid. A step increase of the transmitted light reading occurs after hydration of the strip, and the occurrence of this step increase is used to start a predetermined incubation period. At the expiration of the incubation period, another light transmission measurement is made which is indicative of an analyte concentration in the sample fluid (such as glucose concentration in a whole blood sample).
    • 本发明涉及一种通过使用通过条带的环境光的测量被动地确定样品流体在分析物条上的应用的方法。 将样品流体(例如全血)施加到试剂基质上,并且在施加样品流体之前和之后周期性地测量透过基质的环境光的量。 透射光读数的逐步增加发生在条带的水合之后,并且使用该步骤增加的发生来开始预定的潜伏期。 在孵育期满时,进行另一次透射测量,其表示样品流体中的分析物浓度(例如全血样品中的葡萄糖浓度)。
    • 3. 发明授权
    • Electrical plug type connector
    • 电插头型连接器
    • US09130299B2
    • 2015-09-08
    • US12148947
    • 2008-04-23
    • Otto NachbauerRichard RiedelChristian Eiletz
    • Otto NachbauerRichard RiedelChristian Eiletz
    • B23P19/00H01R13/00H01R13/52
    • H01R13/5202H01R13/745
    • Method for producing an electrically conductive connection between a component (1), which is positioned in a housing, is equipped with electrical contacts and is accessible from the outside through an opening located in a wall of the housing, and a feed source, using a plug-type element (6), which is equipped with electrical mating contacts (7) and is fitted to the end of an electrical line, which is connected to the feed source and has at least two insulated conductors (8). The plug-type element (6)together with conductors (8) connected thereto is first fixed on one end of a holder (9) made from plastic, whose outer dimensions are smaller than the clear width of the opening (4) of the housing (3). Then the plug-type element (6) is passed through the opening (4) of the housing (3) by means of the holder (9) and is plugged onto the contacts (2) of the component (1). Finally the holder (9) is detached from the plug-type element (6) once the end position of the plug-type element (6) has been reached, whilst remaining in the housing (3) or in its opening (4). The holder (9) may also support a closure (12) to close the opening (4).
    • 在位于壳体中的部件(1)之间产生导电连接的方法,其配备有电触点,并且可通过位于壳体的壁中的开口从外部进入,并且使用 插头式元件(6),其配备有电配合触点(7)并且安装到电线的端部,该电线连接到馈电源并且具有至少两个绝缘导体(8)。 插头式元件(6)连同其上的导体(8)首先固定在由塑料制成的保持器(9)的一端上,该外壳尺寸小于外壳的开口(4)的透明宽度 (3)。 然后,插头式元件(6)通过保持器(9)穿过壳体(3)的开口(4)并被插入到部件(1)的触点(2)上。 一旦达到插头式元件(6)的端部位置,同时保持在壳体(3)或其开口(4)中,则最后保持器(9)与插头型元件(6)分离。 保持器(9)还可以支撑封闭件(12)以封闭开口(4)。
    • 4. 发明申请
    • Electrical plug type connector
    • 电插头型连接器
    • US20080280481A1
    • 2008-11-13
    • US12148947
    • 2008-04-23
    • Otto NachbauerRichard RiedelChristian Eiletz
    • Otto NachbauerRichard RiedelChristian Eiletz
    • H01R13/56
    • H01R13/5202H01R13/745
    • Method for producing an electrically conductive connection between a component (1), which is positioned in a housing, is equipped with electrical contacts and is accessible from the outside through an opening located in a wall of the housing, and a feed source, using a plug-type element (6), which is equipped with electrical mating contacts (7) and is fitted to the end of an electrical line, which is connected to the feed source and has at least two insulated conductors (8). The plug-type element (6)together with conductors (8) connected thereto is first fixed on one end of a holder (9) made from plastic, whose outer dimensions are smaller than the clear width of the opening (4) of the housing (3). Then the plug-type element (6) is passed through the opening (4) of the housing (3) by means of the holder (9) and is plugged onto the contacts (2) of the component (1). Finally the holder (9) is detached from the plug-type element (6) once the end position of the plug-type element (6) has been reached, whilst remaining in the housing (3) or in its opening (4).
    • 在位于壳体中的部件(1)之间产生导电连接的方法,其配备有电触点,并且可通过位于壳体的壁中的开口从外部进入,并且使用 插头式元件(6),其配备有电配合触点(7)并且安装到电线的端部,该电线连接到馈电源并且具有至少两个绝缘导体(8)。 插头式元件(6)连同其上的导体(8)首先固定在由塑料制成的保持器(9)的一端上,该外壳尺寸小于外壳的开口(4)的透明宽度 (3)。 然后,插头式元件(6)通过保持器(9)穿过壳体(3)的开口(4)并被插入到部件(1)的触点(2)上。 一旦达到插头式元件(6)的端部位置,同时保持在壳体(3)或其开口(4)中,则最后保持器(9)与插头型元件(6)分离。
    • 5. 发明授权
    • Apparatus and method for analyzing a body fluid
    • 用于分析身体液体的装置和方法
    • US5246858A
    • 1993-09-21
    • US661810
    • 1991-02-27
    • Steven R. ArbuckleWilliam R. BoydMichael E. GrantMark A. GregoryRussell T. GrayFriedrich JostDaniel L. KennedyDino PerinRichard RiedelDavid E. StorvickJohn W. Stoughton
    • Steven R. ArbuckleWilliam R. BoydMichael E. GrantMark A. GregoryRussell T. GrayFriedrich JostDaniel L. KennedyDino PerinRichard RiedelDavid E. StorvickJohn W. Stoughton
    • G01N21/47G01N21/77G01N21/86G01N33/52
    • G01N21/8483G01N2021/478G01N2201/1214G01N2201/122G01N2201/12723Y10T436/10
    • A method and apparatus (10) for determining the remission of a chemistry (106) which reacts with a medically significant component of a body fluid. The remission of the chemistry (106) changes as it reacts. The method and apparatus (10) include irradiating the chemistry (106) with a radiation source (182), detecting remissions of radiation from the chemistry (106) with a radiation detector (300), providing a radiation pathway (164) between the source (182) and the chemistry (106), providing a remission pathway (164) between the chemistry (106) and the detector (300), and detecting the rate of change of remission of the chemistry (106) with respect to time. The irradiating, detecting and rate detecting steps and apparatus comprise initially irradiating the chemistry (106) at a first time rate and detecting remissions therefrom, comparing remission data from remission readings spaced apart by a first number of intervening remission readings, and determining when the difference between compared readings exceeds a first predetermined limit. The time rate of irradiation of the chemistry is changed once the difference between compared readings exceeds the first limit. Remission data from remission readings spaced apart by a second number of intervening remission readings are then compared. The method and apparatus next determine when the difference between compared readings no longer exceeds a second predetermined limit. The last remission reading is then converted to the concentration of the medically significant component of the body fluid.
    • 一种用于确定化学物质(106)的缓解的方法和装置(10),其与体液的医学上重要的组分反应。 化学物质(106)的缓解随着反应而发生变化。 该方法和装置(10)包括用辐射源(182)照射化学物质(106),用辐射检测器(300)检测来自化学物质(106)的辐射的放射,提供源之间的辐射通路(164) (106)和化学物质(106),在化学物质(106)和检测器(300)之间提供缓释途径(164),以及检测化学物质(106)相对于时间的缓解变化率。 照射,检测和速率检测步骤和装置包括首先以第一时间速率辐射化学物质(106)并检测其中的缓解,将缓释数据与间隔开的缓冲读数与第一数量的介入缓解读数进行比较,以及确定何时差异 比较读数超过第一预定极限。 一旦比较读数之间的差超过第一限制,化学物质的照射时间变化就会改变。 然后比较缓冲读数与间隔第二数量的介入缓解读数的缓解数据。 该方法和装置接下来确定比较读数之间的差异何时不再超过第二预定极限。 然后将最后的缓解读数转化为体液的医学重要组分的浓度。
    • 6. 发明申请
    • Arrangement for the local monitoring of functions
    • 安排地方监督职能
    • US20070024411A1
    • 2007-02-01
    • US11407388
    • 2006-04-19
    • Rainer LangOtto NachbauerMichael HelgertRichard Riedel
    • Rainer LangOtto NachbauerMichael HelgertRichard Riedel
    • H01C7/13
    • G01K1/12G01K7/22
    • A local monitoring of functions, in which a sensor is connected to a voltage source via an electrical conductor, in which the sensor is arranged, together with at least one further electrical or electronic component, on a printed circuit board (9) provided with conductor tracks, the sensor being electrically conductively connected, by means of the conductor tracks of the printed circuit board (9), to the component connected to the conductor tracks, and in which the printed circuit board (9) is arranged in a housing (15). In order to supply a secure and immovable hold, the printed circuit board (9) with conductors (7, 8) connected to the conductor tracks is arranged in a holder (17), which is made from a mechanically stable insulating material, accommodates the printed circuit board (9) and has limiting stops (19, 20, 21) for the printed circuit board (9) and laterally protruding latching elements (22, 23). The holder (17) with the printed circuit board (9) inserted is latched in the housing (15), in a prescribed position in the housing (15), by means of the latching elements (22, 23), and the housing (15) is filled with a compound (27) which surrounds the holder (17) and the printed circuit board (9) without any cavities.
    • 将传感器经由电导体连接到传感器的功能的局部监视与其中布置有传感器的至少一个另外的电气或电子部件连接在设置有导体的印刷电路板(9)上 轨道,传感器通过印刷电路板(9)的导体轨道导电连接到连接到导体轨道的部件,并且其中印刷电路板(9)布置在壳体(15)中 )。 为了提供牢固和不可移动的保持,连接到导体轨道的导体(7,8)的印刷电路板(9)布置在由机械稳定的绝缘材料制成的保持器(17)中, 印刷电路板(9),并具有用于印刷电路板(9)和横向突出的锁定元件(22,23)的限制止挡件(19,20,21)。 插入有印刷电路板(9)的保持器(17)通过闩锁元件(22,23)和壳体(15)在壳体(15)中的规定位置处被锁定在壳体(15)中 15)填充有围绕保持器(17)和印刷电路板(9)而没有任何空腔的化合物(27)。
    • 8. 发明授权
    • Compositions of and new uses for N-acylanilinobutyric acids
    • N-酰基酰氨基丁酸的组合物和新用途
    • US4205088A
    • 1980-05-27
    • US785959
    • 1977-04-08
    • Wolfgang SchoetensackRichard Riedel
    • Wolfgang SchoetensackRichard Riedel
    • A61K31/195
    • A61K31/195
    • Pharmaceutically-acceptable compositions containing, as an active ingredient, at least one N-acylanilinobutyric acid have uses unrelated to the choleretic activity suggested in U.S. Pat. No. 3,780,095. Moreover, the further uses generally involve administration of smaller doses than would be required to obtain a choleretic effect.The new uses include: (a) increasing the gastrointestinal enzyme secretion and (b) tonicizing the cardiovascular system. The increase of the gastrointestinal enzyme secretion is applied in the treatment of different diseases, such as treatment of sprue, treatment of indigestion, treatment of acute and chronic pancreatitis, therapy for degenerated intestine mucous membrane, treatment of stomach spasms, treatment of stomach ulcers, treatment of diseases where the application of an antigastrin is indicated. The tonicising of the cardiovascular system is applied in, e.g., increasing the circulation of blood in internal organs, increasing the heart force, treating disturbances in the liver function.
    • 含有作为活性成分的至少一种N-酰基酰氨基丁酸的药学上可接受的组合物具有与美国专利No。 3,780,095。 此外,进一步的用途通常包括施用比获得胆汁效果所需要的更小的剂量。 新用途包括:(a)增加胃肠酶分泌和(b)增强心血管系统。 胃肠酶分泌的增加用于治疗不同的疾病,如注射治疗,消化不良治疗,治疗急性和慢性胰腺炎,治疗退行性肠粘膜,治疗胃痉挛,治疗胃溃疡, 治疗应用抗胃酸素的疾病。 心血管系统的滋养应用于例如增加内脏中血液的循环,增加心脏力,治疗肝功能紊乱。