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1. 发明授权

US09347038B2 Compositions and methods for processing sperm 有权
标题翻译：精子加工的组成和方法
公开(公告)号：US09347038B2
公开(公告)日：2016-05-24
申请号：US13823843
申请日：2012-06-01
申请人： Richard Lenz , Juan Moreno , Ramakrishnan Vishwanath
发明人： Richard Lenz , Juan Moreno , Ramakrishnan Vishwanath
IPC分类号： A01N1/02 , C12N5/076 , G01N15/14
CPC分类号： C12N5/0609 , A01N1/0226 , A01N1/0284 , C12N5/061 , C12N5/0612 , C12N2500/30 , C12N2500/38 , C12N2502/04 , G01N15/1459 , G01N2015/149
摘要： The present invention relates to compositions and methods for the handling of processed sperm including samples that are freshly collected, those transported as fresh samples, samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the cell. Trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the ability to fertilize, produce an embryo and a healthy offspring. The present invention relates to novel compounds that can be added to the sperm cell sample to reduce the traumatic effects of physical stress during mild as well as extensive sperm cell processing, methods of using the compounds in standard sperm processing procedures, the end products made from these methods including sperm and embryos, as well as methods of using those end products in assisted reproductive biology techniques in animals.
摘要翻译：本发明涉及用于处理加工精子的组合物和方法，包括新鲜收集的样品，作为新鲜样品运输的样品，被冷冻和解冻的样品，分为一个或多个亚种群的样品，以及另外处理或处理的样品对细胞造成创伤。创伤可以降低精子的活力，生育力，生存力和整体完整性，降低受精，产生胚胎和健康后代的能力。本发明涉及可以添加到精子细胞样品中以减轻轻度和广泛精子细胞处理期间物理应激的创伤作用的新型化合物，在标准精子加工程序中使用化合物的方法，由这些方法包括精子和胚胎，以及在动物的辅助生殖生物学技术中使用这些终产物的方法。

2. 发明申请

US20130183656A1 COMPOSITIONS AND METHODS FOR IMPROVING THE QUALITY OF PROCESSED SPERM 有权
标题翻译：用于改善加工质量的组合物和方法
公开(公告)号：US20130183656A1
公开(公告)日：2013-07-18
申请号：US13823843
申请日：2012-06-01
申请人： Richard Lenz , Juan Moreno , Ramakrishnan Vishwanath
发明人： Richard Lenz , Juan Moreno , Ramakrishnan Vishwanath
IPC分类号： A01N1/02
CPC分类号： C12N5/0609 , A01N1/0226 , A01N1/0284 , C12N5/061 , C12N5/0612 , C12N2500/30 , C12N2500/38 , C12N2502/04 , G01N15/1459 , G01N2015/149
摘要： The present invention relates to compositions and methods for the handling of processed sperm including samples that are freshly collected, those transported as fresh samples, samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the cell. Trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the ability to fertilize, produce an embryo and a healthy offspring. The present invention relates to novel compounds that can be added to the sperm cell sample to reduce the traumatic effects of physical stress during mild as well as extensive sperm cell processing, methods of using the compounds in standard sperm processing procedures, the end products made from these methods including sperm and embryos, as well as methods of using those end products in assisted reproductive biology techniques in animals.
摘要翻译：本发明涉及用于处理加工精子的组合物和方法，包括新鲜收集的样品，作为新鲜样品运输的样品，被冷冻和解冻的样品，分为一个或多个亚种群的样品，以及另外处理或处理的样品对细胞造成创伤。创伤可以降低精子的活力，生育力，生存力和整体完整性，降低受精，产生胚胎和健康后代的能力。本发明涉及可以添加到精子细胞样品中以减轻轻度和广泛精子细胞处理期间物理应激的创伤作用的新型化合物，在标准精子加工程序中使用化合物的方法，由这些方法包括精子和胚胎，以及在动物的辅助生殖生物学技术中使用这些终产物的方法。

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