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1. 发明授权

US09561001B2 Fluid handling cassette system for body fluid analyzer 有权
标题翻译：流体处理盒系统用于体液分析仪
公开(公告)号：US09561001B2
公开(公告)日：2017-02-07
申请号：US12986112
申请日：2011-01-06
申请人： Richard Keenan , Jeff Chiou , Jennifer Gable , Ken Li , Roger Tong , Mike Recknor , James R. Braig
发明人： Richard Keenan , Jeff Chiou , Jennifer Gable , Ken Li , Roger Tong , Mike Recknor , James R. Braig
IPC分类号： G01N33/50 , A61B5/157
CPC分类号： A61B5/157 , G01N33/50
摘要： A fluid handling system for use in bodily fluid analysis. The system comprises a first fluid handling module configured to interface with a main instrument. The first fluid handling module has a first fluid handling network and the first fluid handling network includes an infusate passage and an infusion fluid pressure member suitable for moving fluid within the infusate passage. The fluid handling system also has a second fluid handling module separate from the first module which is configured to interface with the main instrument. The second fluid handling module has a second fluid handling network and at least one sample analysis cell which is accessible via the second fluid handling network. The first and second modules are configured to interconnect and provide fluid communication between the first and second fluid handling network and the sample cells.
摘要翻译：用于体液分析的流体处理系统。该系统包括被配置为与主仪器接口的第一流体处理模块。第一流体处理模块具有第一流体处理网络，并且第一流体处理网络包括适于在输注通道内移动流体的输注通道和输液流体压力构件。流体处理系统还具有与第一模块分离的第二流体处理模块，第一模块被配置为与主仪器相接触。第二流体处理模块具有第二流体处理网络和可经由第二流体处理网络访问的至少一个样品分析单元。第一和第二模块被配置为在第一和第二流体处理网络和样品池之间互连并提供流体连通。

2. 发明申请

US20110218411A1 FLUID HANDLING CASSETTE SYSTEM FOR BODY FLUID ANALYZER 有权
标题翻译：液体流动分析仪的流体处理系统
公开(公告)号：US20110218411A1
公开(公告)日：2011-09-08
申请号：US12986112
申请日：2011-01-06
申请人： Richard Keenan , Jeff Chiou , Jennifer Gable , Ken Li , Roger Tong , Mike Recknor , James R. Braig
发明人： Richard Keenan , Jeff Chiou , Jennifer Gable , Ken Li , Roger Tong , Mike Recknor , James R. Braig
IPC分类号： A61B5/157 , G01N33/50
CPC分类号： A61B5/157 , G01N33/50
摘要： A fluid handling system for use in bodily fluid analysis. The system comprises a first fluid handling module configured to interface with a main instrument. The first fluid handling module has a first fluid handling network and the first fluid handling network includes an infusate passage and an infusion fluid pressure member suitable for moving fluid within the infusate passage. The fluid handling system also has a second fluid handling module separate from the first module which is configured to interface with the main instrument. The second fluid handling module has a second fluid handling network and at least one sample analysis cell which is accessible via the second fluid handling network. The first and second modules are configured to interconnect and provide fluid communication between the first and second fluid handling network and the sample cells.
摘要翻译：用于体液分析的流体处理系统。该系统包括被配置为与主仪器接口的第一流体处理模块。第一流体处理模块具有第一流体处理网络，并且第一流体处理网络包括适于在输注通道内移动流体的输注通道和输液流体压力构件。流体处理系统还具有与第一模块分离的第二流体处理模块，第一模块被配置为与主仪器相接触。第二流体处理模块具有第二流体处理网络和可经由第二流体处理网络访问的至少一个样品分析单元。第一和第二模块被配置为在第一和第二流体处理网络和样品池之间互连并提供流体连通。

3. 发明申请

US20070239096A1 ANTI-CLOTTING APPARATUS AND METHODS FOR FLUID HANDLING SYSTEM 有权
标题翻译：用于流体处理系统的防粘装置和方法
公开(公告)号：US20070239096A1
公开(公告)日：2007-10-11
申请号：US11734242
申请日：2007-04-11
申请人： Richard Keenan , Jeff Chiou
发明人： Richard Keenan , Jeff Chiou
IPC分类号： A61M37/00
CPC分类号： G01N29/00 , A61B5/14532 , A61B5/14546 , A61B5/14557 , A61M1/3672 , A61M5/1723 , A61M2005/1404 , A61M2205/3306 , A61M2230/201
摘要： Methods and apparatus are provided for determining the concentration of an analyte in a sample, such as an analyte in a sample of bodily fluid. In some embodiments, a method for maintaining clear passageways in an extracorporeal blood flow system includes intermittently providing one or more anti-clotting agents to a passageway of the extracorporeal blood flow system. In some embodiments, an extracorporeal blood flow system includes a passageway and a device operatively connected to provide one or more anti-clotting agents to a least a portion of said passageway.
摘要翻译：提供了用于确定样品（例如体液样品中的分析物）中的分析物的浓度的方法和装置。在一些实施方案中，用于在体外血流系统中维持清晰通道的方法包括间歇地向体外血流系统的通道提供一种或多种抗凝血剂。在一些实施方案中，体外血液流动系统包括通路和操作性连接的装置，以向所述通道的至少一部分提供一种或多种抗凝血剂。

4. 发明授权

US08425444B2 Anti-clotting apparatus and methods for fluid handling system 有权
标题翻译：用于流体处理系统的抗凝装置和方法
公开(公告)号：US08425444B2
公开(公告)日：2013-04-23
申请号：US11734242
申请日：2007-04-11
申请人： Richard Keenan , Jeff Chiou
发明人： Richard Keenan , Jeff Chiou
IPC分类号： A61M37/00
CPC分类号： G01N29/00 , A61B5/14532 , A61B5/14546 , A61B5/14557 , A61M1/3672 , A61M5/1723 , A61M2005/1404 , A61M2205/3306 , A61M2230/201
摘要： Methods and apparatus are provided for determining the concentration of an analyte in a sample, such as an analyte in a sample of bodily fluid. In some embodiments, a method for maintaining clear passageways in an extracorporeal blood flow system includes intermittently providing one or more anti-clotting agents to a passageway of the extracorporeal blood flow system. In some embodiments, an extracorporeal blood flow system includes a passageway and a device operatively connected to provide one or more anti-clotting agents to a least a portion of said passageway.
摘要翻译：提供了用于确定样品（例如体液样品中的分析物）中的分析物的浓度的方法和装置。在一些实施方案中，用于在体外血流系统中维持清晰通道的方法包括间歇地向体外血流系统的通道提供一种或多种抗凝血剂。在一些实施方案中，体外血液流动系统包括通路和操作性连接的装置，以向所述通道的至少一部分提供一种或多种抗凝血剂。

5. 发明授权

US08140140B2 Analyte detection system for multiple analytes 有权
标题翻译：多种分析物的分析物检测系统
公开(公告)号：US08140140B2
公开(公告)日：2012-03-20
申请号：US11314176
申请日：2005-12-21
申请人： Bernhard B. Sterling , James R. Braig , Kenneth G. Witte , Peter Rule , Richard Keenan , W. Dale Hall
发明人： Bernhard B. Sterling , James R. Braig , Kenneth G. Witte , Peter Rule , Richard Keenan , W. Dale Hall
IPC分类号： A61B5/1455
CPC分类号： A61M5/1723 , A61B5/14532 , A61B5/14546 , A61B5/14557 , A61B5/1495 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150755 , A61B5/150862 , A61B5/150992 , A61B5/153 , A61B5/155 , A61B5/157 , A61M5/14212 , A61M5/14232 , A61M5/16854 , A61M2205/12 , A61M2230/20 , A61M2230/201 , G01N1/14 , G01N21/05 , G01N21/274 , G01N21/35 , G01N2021/0346
摘要： An apparatus for analyzing the composition of bodily fluid. The apparatus comprises a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient; and a pump unit in operative engagement with the fluid handling network. The pump unit has an infusion mode in which the pump unit is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode in which the pump unit is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus further comprises a spectroscopic analyzer positioned to analyze at least a portion of the sample; a processor in communication with or incorporated into the spectroscopic analyzer; and stored program instructions executable by the processor to obtain measurements of two or more properties of the sample. In one implementation, the pump unit comprises a first pump operable in the infusion mode but not in the sample draw mode, and a second pump operable in the sample draw mode but not in the infusion mode.
摘要翻译：一种用于分析体液组成的装置。该装置包括流体处理网络，其包括被配置为保持患者体内与体液的流体连通的患者端; 以及与所述流体处理网络操作地接合的泵单元。泵单元具有输注模式，其中泵单元可操作以通过患者端向患者输送输注流体，以及抽样模式，其中泵单元可操作以从患者抽取体液样本，通过病人结束所述设备还包括定位成分析样品的至少一部分的光谱分析仪; 与光谱分析仪通信或并入其中的处理器; 以及可由处理器执行的存储的程序指令，以获得样本的两个或多个属性的测量。在一个实施方案中，泵单元包括可在输液模式中操作但不在样品抽取模式中的第一泵，以及可在样品抽取模式中操作但不在输注模式中的第二泵。

6. 发明授权

US07972296B2 Fluid component analysis system and method for glucose monitoring and control 有权
标题翻译：用于葡萄糖监测和控制的流体成分分析系统和方法
公开(公告)号：US07972296B2
公开(公告)日：2011-07-05
申请号：US12249831
申请日：2008-10-10
申请人： James R. Braig , Richard Keenan , Peter Rule , Gil Rivas , Mahesh Seetharaman
发明人： James R. Braig , Richard Keenan , Peter Rule , Gil Rivas , Mahesh Seetharaman
IPC分类号： A61M31/00
CPC分类号： A61B5/4839 , A61B5/1427 , A61B5/14532 , A61B5/14535 , A61B5/14546 , A61B5/1455 , A61B5/14557 , A61B5/1495 , A61B5/15003 , A61B5/150221 , A61B5/150229 , A61B5/150267 , A61B5/150755 , A61B5/150786 , A61B5/150862 , A61B5/150992 , A61B5/153 , A61B5/155 , A61B5/157 , A61B5/412 , A61B5/7475 , A61M5/16827 , A61M5/1723 , A61M2005/1404 , A61M2005/14208 , A61M2005/1726 , A61M2205/12 , A61M2205/3303 , A61M2209/084 , A61M2230/201 , G06F19/00 , G06F19/3468
摘要： Disclosed are methods and apparatus for determining analyte concentration in a sample such as bodily fluid. Systems and methods disclosed herein can also include a treatment dosing system to infuse or inject a treatment drug (e.g. insulin or glucose) and provide glycemic control. The dose of the treatment drug may be based on the concentration of the analyte or the average value for the concentration of the analyte and/or the rate of change of the value of the concentration of the analyte.
摘要翻译：公开了用于测定诸如体液的样品中的分析物浓度的方法和装置。本文公开的系统和方法还可以包括注射或注射治疗药物（例如胰岛素或葡萄糖）并提供血糖控制的治疗剂量系统。治疗药物的剂量可以基于分析物的浓度或分析物浓度的平均值和/或分析物浓度值的变化率。

7. 发明授权

US07905260B2 Router dust collection assembly 有权
标题翻译：路由器集尘装置
公开(公告)号：US07905260B2
公开(公告)日：2011-03-15
申请号：US12349083
申请日：2009-01-06
申请人： Richard Keenan
发明人： Richard Keenan
IPC分类号： B27G19/00 , B23Q11/00
CPC分类号： B23Q11/0046 , Y10T83/207 , Y10T409/304088
摘要： A dust collector is provided for use with a router that is mounted to the underside of a router table. The device serves as a means for collecting dust from both upper and lower surfaces of a cutting tool. The dust collector includes a flexible cup attachable to the underside of the router table, a vacuum hose opening on the cup connectable to a workshop vacuum hose and reducer fitting in combination are attachable to a router table fence and to one of two small openings of a “T” connector fitting on the other end, a vacuum hose attachable to the vacuum hose opening of the cup on one end and attachable to the other of two small openings of the “T” connector on the other end, a larger opening on the “T” connector connectable to a vacuum hose of a workshop vacuum, which in combination.
摘要翻译：提供集尘器用于安装在路由器台的下侧的路由器。该装置用作从切割工具的上表面和下表面收集灰尘的装置。集尘器包括可连接到路面工作台的下侧的柔性杯，可连接到车间真空软管的杯子上的真空软管开口和组合的减速器配件可附接到路由器台栅栏和两个小的开口之一在另一端的“T”型连接器配件，一端连接到杯子的真空软管开口的真空软管，并可连接到另一端的“T”连接器的两个小开口中的另一个，另一端的较大开口 “T”连接器可连接到车间真空的真空软管，它们组合在一起。

8. 发明申请

US20080284167A1 LOW-VOLUME FITTINGS 审中-公开
标题翻译：低容量配件
公开(公告)号：US20080284167A1
公开(公告)日：2008-11-20
申请号：US12122009
申请日：2008-05-16
申请人： Eugene Lim , Richard Keenan , Michael Butler
发明人： Eugene Lim , Richard Keenan , Michael Butler
IPC分类号： F16L25/00
CPC分类号： F16L25/10 , A61M39/10 , A61M2039/1033 , A61M2206/11 , A61M2206/20
摘要： Fitting that is compatible with standard fittings is described. In one embodiment, the end of one of a matched set of fittings is provided with an elastomeric material. The elastomeric material deforms when the matched fittings are coupled, resulting in a reduced volume. In certain embodiments, a tube is provided through the tube which is attached at a proximal end and extends to the distal end of the elastomeric material. When the fitting are coupled the tube protrudes past the end of the elastomeric material and into the coupled fitting. In certain embodiments the fitting otherwise conforms to International Standard ISO 594.
摘要翻译：描述与标准配件兼容的配件。在一个实施例中，匹配的一组配件之一的端部设置有弹性体材料。当匹配的配件联接时，弹性体材料变形，导致体积减小。在某些实施例中，通过管提供管，其在近端附接并延伸到弹性体材料的远端。当配件联接时，管突出穿过弹性体材料的端部并且进入联接的配件中。在某些实施例中，该装置否则符合国际标准ISO 594。

9. 发明申请

US20080072663A1 ACCURATE AND TIMELY BODY FLUID ANALYSIS 审中-公开
标题翻译：精确和及时的体液分析
公开(公告)号：US20080072663A1
公开(公告)日：2008-03-27
申请号：US11839487
申请日：2007-08-15
申请人： Richard Keenan , Jeffrey Chiou , Roger Tong , Michael Recknor , Ken Li , James Braig , David Callicoat , Jennifer Gable
发明人： Richard Keenan , Jeffrey Chiou , Roger Tong , Michael Recknor , Ken Li , James Braig , David Callicoat , Jennifer Gable
IPC分类号： G01N33/00 , B01J19/00 , B04B5/10
CPC分类号： G01N35/1095 , A61B5/14532 , A61B5/14557 , A61B5/15003 , A61B5/150221 , A61B5/150229 , A61B5/150236 , A61B5/150244 , A61B5/150267 , A61B5/150305 , A61B5/150755 , A61B5/150786 , A61B5/150824 , A61B5/153 , A61B5/157 , A61M1/3621 , A61M5/14 , A61M5/1415 , A61M2005/1404 , A61M2005/1726 , A61M2230/201 , B01L3/502 , B01L3/50273 , B01L3/52 , B01L2200/10 , B01L2300/0816 , B01L2400/0478 , B01L2400/0633 , G01N21/35
摘要： A method of extracting and analyzing bodily fluids from a patient at the point of care for the patient is provided. The method comprises establishing fluid communication between an analyte detection system and a bodily fluid in the patient. A portion of the bodily fluid is drawn from the patient. A first component of the bodily fluid is separated from the drawn portion, while the analyte detection system remains in fluid communication with the patient. The analyte detection system analyzes the first component to measure a concentration of an analyte in an accurate and timely manner.
摘要翻译：提供了在患者护理点从患者提取和分析体液的方法。该方法包括在患者体内建立分析物检测系统和体液之间的流体连通。体液的一部分从患者身上抽出。分析物检测系统与患者保持流体连通，将体液的第一组分与拉出部分分离。分析物检测系统分析第一个成分，以准确和及时的方式测量分析物的浓度。

10. 发明申请

US20070083143A1 Anti-Clotting Apparatus and Methods for Fluid Handling System 有权
标题翻译：抗凝装置及流体处理系统的方法
公开(公告)号：US20070083143A1
公开(公告)日：2007-04-12
申请号：US11314731
申请日：2005-12-21
申请人： James Braig , Richard Keenan
发明人： James Braig , Richard Keenan
IPC分类号： A61M37/00
CPC分类号： A61B5/157 , A61B5/14532 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150755 , A61B5/150862 , A61B5/150992 , A61B5/153 , A61B5/155 , A61M5/14212 , A61M2230/20 , G01N21/35
摘要： A method for maintaining clear passageways in an extracorporeal blood flow system. The method comprises intermittently providing one or more anti-clotting agents to a passageway of the extracorporeal blood flow system. Also disclosed is an extracorporeal blood flow system. The system comprises a passageway, and a device operatively connected to provide one or more anti-clotting agents to a least a portion of said passageway.
摘要翻译：一种用于在体外血液流动系统中保持清晰通道的方法。该方法包括间歇地向体外血液流通系统的通道提供一种或多种抗凝血剂。还公开了一种体外血液流动系统。该系统包括通道和可操作地连接以向所述通道的至少一部分提供一种或多种抗凝血剂的装置。

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