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1. 发明申请

US20080096927A1 Combination Therapy for Treating Cyclooxygenase-2 Mediated Diseases or Conditions in Patients at Risk of Thrombotic Cardiovascular Events 审中-公开
标题翻译：治疗环氧合酶-2介导的疾病或病情的组合治疗患有血栓性心血管事件风险的患者
公开(公告)号：US20080096927A1
公开(公告)日：2008-04-24
申请号：US11660195
申请日：2005-08-19
申请人： Thomas Simon , Alise Reicin , Richard Hunt
发明人： Thomas Simon , Alise Reicin , Richard Hunt
IPC分类号： A61K31/4439 , A61K31/365 , A61K31/444 , A61P19/00 , A61P9/00
CPC分类号： A61K45/06 , A61K31/4152 , A61K31/4439 , A61K2300/00
摘要： The invention encompasses a pharmaceutical composition comprising a therapeutically effective amount of a cyclooxygenase-2 selective inhibitor selected from rofecoxib and etoricoxib or a pharmaceutically acceptable salt thereof, and a therapeutically effective amount of a proton pump inhibitor selected from the group consisting of: omeprazole, lansoprazole, rabeprazole, pantoprazole, and esomeprazole, or a pharmaceutically acceptable salt of any of the aforementioned, in combination with a pharmaceutically acceptable carrier. The invention also encompasses a method for treating a cyclooxygenase-2 mediated disease or condition in a human patient at risk of a thrombotic cardiovascular event, wherein the patient is on aspirin therapy to reduce the risk of the thrombotic cardiovascular event, comprising administering to the patient this pharmaceutical composition.
摘要翻译：本发明包括药物组合物，其包含治疗有效量的选自罗非昔布和依托昔康的环加氧酶-2选择性抑制剂或其药学上可接受的盐，以及治疗有效量的选自以下的质子泵抑制剂：奥美拉唑，兰索拉唑，雷贝拉唑，泮托拉唑和艾美拉唑，或任何上述药学上可接受的盐与药学上可接受的载体组合。本发明还包括用于治疗患有血栓性心血管事件危险的人类患者中环氧合酶-2介导的疾病或病症的方法，其中所述患者服用阿司匹林治疗以降低血栓性心血管事件的风险，包括给予患者该药物组合物。

2. 发明申请

US20050215611A1 Combination therapy for treating cyclooxygenase-2 mediated diseases in patients at risk of thrombotic cardiovascular events 审中-公开
标题翻译：在血栓性心血管事件危险的患者中治疗环氧合酶-2介导的疾病的组合疗法
公开(公告)号：US20050215611A1
公开(公告)日：2005-09-29
申请号：US10513085
申请日：2003-05-09
申请人： Richard Hunt , Thomas Simon
发明人： Richard Hunt , Thomas Simon
IPC分类号： A61K31/415
CPC分类号： A61K31/415
摘要： The present invention encompasses a method for treating a chronic cyclooxygenase-2 mediated disease or condition and reducing the risk of a thrombotic cardiovascular event in a human patient in need of such treatment and at risk of a thrombotic cardiovascular event comprising orally concomitantly or sequentially administering to said patient a cyclooxygenase-2 selective inhibitor in an amount effective to treat the cyclooxygenase-2 mediated disease or condition and nitric oxide releasing aspirin in an amount effective to reduce the risk of the thrombotic cardiovascular event while maintaining a high level of upper gastrointestinal safety and tolerability. The invention also encompasses a method for treating a chronic cyclooxygenase-2 mediated disease or condition and reducing the risk of a thrombotic cardiovascular event in a human patient in need of such treatment and at risk of a thrombotic cardiovascular event comprising orally concomitantly or sequentially administering to said patient a nitric oxide releasing-cyclooxygenase-2 selective inhibitor in an amount effective to treat the cyclooxygenase-2 mediated disease or condition and aspirin in an amount effective to reduce the risk of the thrombotic cardiovascular event while maintaining a high level of upper gastrointestinal safety and tolerability. Pharmaceutical compositions are also encompassed.
摘要翻译：本发明包括一种治疗慢性环氧合酶-2介导的疾病或病症并减少需要这种治疗的人类患者血栓性心血管事件的风险并且具有血栓性心血管事件的风险的方法，包括口服伴随地或依次给予所述患者以有效治疗环氧合酶-2介导的疾病或病症和一氧化氮释放阿司匹林的量的环氧合酶-2选择性抑制剂的量有效降低血栓形成心血管事件的风险，同时保持高水平的上消化道安全性，耐受性本发明还包括一种治疗慢性环氧合酶-2介导的疾病或病症并降低需要这种治疗的人类患者血栓性心血管事件的风险并且具有血栓性心血管事件的风险的方法，其包括口服同时或依次给予所述患者以有效治疗环氧合酶-2介导的疾病或病症和阿司匹林的量的一氧化氮释放 - 环氧合酶-2选择性抑制剂，其量可有效降低血栓形成心血管事件的风险，同时保持高水平的上消化道安全性和耐受性。也包括药物组合物。

3. 发明申请

US20070294044A1 Baud Rate Detection 有权
标题翻译：波特率检测
公开(公告)号：US20070294044A1
公开(公告)日：2007-12-20
申请号：US11629986
申请日：2005-07-01
申请人： Richard Hunt
发明人： Richard Hunt
IPC分类号： G01R23/02
CPC分类号： H04L25/0262
摘要： A method is provided of characterising a data stream of binary symbols, the method comprising sampling the stream at a predetermined rate sufficient to capture at least two samples per binary symbol, identifying the shortest continuous run of samples having the same logic level and assigning a symbol rate to the stream on the basis that the identified run is one symbol in length.
摘要翻译：提供了表征二进制符号的数据流的方法，该方法包括以足以捕获每个二进制符号的至少两个样本的预定速率对流进行采样，识别具有相同逻辑电平的样本的最短连续运行并分配符号基于所识别的运行是长度为一个符号的流量。

4. 发明申请

US20060275717A1 Apparatus and method for extracting condensate 有权
公开(公告)号：US20060275717A1
公开(公告)日：2006-12-07
申请号：US11344288
申请日：2006-01-30
申请人： Joseph Jensen , Michael Faust , Mark Carne , Alan Jackson , Richard Hunt , Brian Kenvyn
发明人： Joseph Jensen , Michael Faust , Mark Carne , Alan Jackson , Richard Hunt , Brian Kenvyn
IPC分类号： F23D11/44
CPC分类号： B64D13/00 , Y02T50/44
摘要： An environmental control system (ECS) for an aircraft may be employed to regulate temperature of air entering a cabin of the aircraft. During conditioning of the air, condensate may form in the air. A multiple-stage condensate extraction unit may be incorporated into the ECS to remove the condensate. The extraction unit may be provided with two fluid collection stages built into a cylindrical duct. The duct may have a bend therein. One of the collection stages may be positioned on an upstream side of the bend while the second one of the stages may be positioned on a downstream side thereof. The combination of the two stages and their positioning on either side of the bend may provide a particularly compact and efficient condensate extraction unit.

5. 发明申请

US20050166629A1 Air conditioning system 审中-公开
标题翻译：空调系统
公开(公告)号：US20050166629A1
公开(公告)日：2005-08-04
申请号：US10874025
申请日：2004-06-22
申请人： Richard Axe , Richard Hunt
发明人： Richard Axe , Richard Hunt
IPC分类号： B64D13/06 , F25B9/00 , F28B9/00 , F25D9/00 , F25D17/04
CPC分类号： F25B9/004 , B64D13/06 , B64D2013/0688 , Y02T50/56
摘要： An air cycle air conditioning system for conditioning recirculating air from an enclosure includes an enclosure air recirculation loop, a first expansion turbine to which hot pressurized working air is provided, a heat exchanger to which a proportion of the hot pressurized working air is provided, from upstream of the first expansion turbine, and in which heat is exchanged to the cooler expanded air from the first expansion turbine. The working air from the heat exchanger expanded by the first expansion turbine and the cooled pressurized working air from the heat exchanger are combined prior to feeding the combined flows to a second expansion turbine. The system including a mixing apparatus in which the recirculating enclosure air from the loop and the cooled combined working air flows from the second expansion turbine are mixed prior to being provided to the enclosure.
摘要翻译：用于调节来自外壳的再循环空气的空气循环空调系统包括外壳空气再循环回路，设置热加压工作空气的第一膨胀涡轮机，设置有一部分热加压工作空气的热交换器，在第一膨胀涡轮机的上游，并且其中热量从第一膨胀涡轮机更换到较冷的膨胀空气。来自热交换器的工作空气由第一膨胀涡轮机膨胀，并且来自热交换器的冷却的加压工作空气在将组合流供给到第二膨胀涡轮机之前组合。包括混合装置的系统在其被提供到外壳之前被混合，在该混合装置中将来自环路的再循环外壳和冷却的组合工作空气从第二膨胀涡轮流出。

6. 外观设计

USD490587S1 Caring clown lollipop 失效
标题翻译：关心小丑棒棒糖
公开(公告)号：USD490587S1
公开(公告)日：2004-06-01
申请号：US29168939
申请日：2002-10-11
申请人： Richard Hunt , Justin Reid
设计人： Richard Hunt , Justin Reid

7. 发明授权

US08301214B1 System and method for providing multi-conductive layer metallic interconnects for superconducting integrated circuits 有权
标题翻译：用于为超导集成电路提供多导电层金属互连的系统和方法
公开(公告)号：US08301214B1
公开(公告)日：2012-10-30
申请号：US12986720
申请日：2011-01-07
申请人： Sergey K. Tolpygo , Denis Amparo , Richard Hunt , John Vivalda , Daniel Yohannes
发明人： Sergey K. Tolpygo , Denis Amparo , Richard Hunt , John Vivalda , Daniel Yohannes
IPC分类号： H01L23/48 , H01L27/00
CPC分类号： H01L39/2493 , H01L23/48 , H01L27/18 , H01L39/025 , H01L39/223 , H01L2924/0002 , H01L2924/00011 , H01L2924/00
摘要： Superconducting integrated circuits require several wiring layers to distribute bias and signals across the circuit, which must cross each other both with and without contacts. All wiring lines and contacts must be fully superconducting, and in the prior art each wiring layer comprises a single metallic thin film. An alternative wiring layer is disclosed that comprises sequential layers of two or more different metals. Such a multi-metallic wiring layer may offer improved resistance to impurity diffusion, better surface passivation, and/or reduction of stress, beyond that which is attainable with a single-metallic wiring layer. The resulting process leads to improved margin and yield in an integrated circuit comprising a plurality of Josephson junctions. Several preferred embodiments are disclosed, for both planarized and non-planarized processes. These preferred and other methods may be applied to digital circuits based on Rapid Single Flux Quantum logic, and to quantum computing using Josephson junction qubits.
摘要翻译：超导集成电路需要多个布线层，以跨越电路分配偏置和信号，这些电路必须彼此交叉，有触点和不带触点。所有布线和触点必须是完全超导的，并且在现有技术中，每个布线层包括单个金属薄膜。公开了包括两种或更多种不同金属的连续层的替代布线层。这样的多金属布线层可以提供改善的杂质扩散阻力，更好的表面钝化和/或应力的减少，超过单金属布线层可达到的。所产生的过程导致包括多个约瑟夫逊结的集成电路中的边缘和产量得到改善。对于平面化和非平面化处理都公开了几个优选实施例。这些优选和其它方法可以应用于基于快速单通量量子逻辑的数字电路，以及使用约瑟夫逊结量子位的量子计算。

8. 发明申请

US20070006607A1 Closed loop air conditioning system 有权
公开(公告)号：US20070006607A1
公开(公告)日：2007-01-11
申请号：US11156802
申请日：2005-06-20
申请人： Richard Hunt
发明人： Richard Hunt
IPC分类号： F25D9/00
CPC分类号： B64D13/06 , B64D2013/0644 , Y02T50/56
摘要： A closed loop air conditioning system for an aircraft includes a compressor stage including at least one power driven compressor, for compressing working fluid, a first expansion turbine over which compressed working fluid is expanded and cooled, a first heat load heat exchanger in which heat from a first heat load is exchanged to the expanded and cooled working fluid, a second expansion turbine over which working fluid from the first heat exchanger is further expanded and cooled, and a second heat load heat exchanger in which heat from a second heat load is exchanged to the further expanded and cooled working fluid.

9. 发明申请

US20060144233A1 Oxygen supply system 失效
标题翻译：供氧系统
公开(公告)号：US20060144233A1
公开(公告)日：2006-07-06
申请号：US10537524
申请日：2003-12-04
申请人： Richard Axe , Richard Hunt
发明人： Richard Axe , Richard Hunt
IPC分类号： B01D53/00
CPC分类号： B64D13/06 , B64D2013/0677 , Y02T50/56
摘要： A method of providing gas to a system which separates from a pressurised supply gas, product gas, includes conditioning the supply gas by both cooling and drying the supply gas.
摘要翻译：向与加压供给气体产品气体分离的系统提供气体的方法包括通过冷却和干燥供应气体来调节供应气体。

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