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1. 发明授权

US5750399A Isoflavone reductase promoter 失效
标题翻译：异黄酮还原酶启动子
公开(公告)号：US5750399A
公开(公告)日：1998-05-12
申请号：US339129
申请日：1994-11-14
申请人： Richard A. Dixon , Nancy L. Paiva , Abraham Oommen
发明人： Richard A. Dixon , Nancy L. Paiva , Abraham Oommen
IPC分类号： A01H5/00 , C12N5/10 , C12N9/02 , C12N15/00 , C12N15/09 , C12N15/82 , C12R1/91 , C12N5/04 , C12N15/29
CPC分类号： C12N9/001 , C12N15/8239
摘要： The invention relates to a promoter and associated control elements derived from the isoflavone reductase gene. The upstream activating region and portions thereof have been characterized as to their ability to control the transcription of operably linked foreign structural genes in legumes as well as in plants which lack the isoflavonoid pathway.
摘要翻译：本发明涉及由异黄酮还原酶基因衍生的启动子和相关控制元件。上游活化区及其部分已被表征为它们在豆类以及缺乏异黄酮途径的植物中控制可操作连接的外来结构基因转录的能力。

2. 发明授权

US07959000B2 Device for collection, storage, retrieval and shipping of hair follicles from animals 有权
公开(公告)号：US07959000B2
公开(公告)日：2011-06-14
申请号：US12054839
申请日：2008-03-25
申请人： Abraham Oommen
发明人： Abraham Oommen
IPC分类号： B65D73/00 , B65D81/02
CPC分类号： A61B10/0096
摘要： The present invention relates to a novel device for the collection, storage, shipping and retrieval of hair follicles from animals for the purpose of isolating DNA or other genetic material from the follicles for analysis. The device has outer flaps for the protection as well as identification of the samples and an inner part where samples are placed. The inner device has thicker base and a clear plastic cover, the easy peel back of which is facilitated by a) low tack adhesives that hold the two together and b) a touch cut on one end, through the base sheet which creates a grip. This makes the device convenient and easy to use, and yet a robust collection device for hair follicles from animals in a farm or real-life situation. Hair follicles can be punched out through the inner device for direct DNA isolation and analysis.

3. 发明申请

US20090078064A1 INSTRUMENT FOR SIMULTANEOUS ANALYSIS OF MULTIPLE SAMPLES USING MULTIPLE DIFFERENTIAL MOBILITY ANALYZERS 审中-公开
标题翻译：使用多个差分移动分析仪同时分析多个样本的仪器
公开(公告)号：US20090078064A1
公开(公告)日：2009-03-26
申请号：US12187054
申请日：2008-08-06
申请人： Abraham Oommen
发明人： Abraham Oommen
IPC分类号： G01N15/02
CPC分类号： G01N15/0266 , G01N2001/2223
摘要： A differential mobility analyzer that is capable of analyzing more than one sample simultaneously, comprising an aerosol generator, a particle classifier and/or a particle counter is disclosed.
摘要翻译：公开了能够同时分析多于一个样品的差分迁移率分析仪，其包括气溶胶发生器，颗粒分级器和/或颗粒计数器。

4. 发明申请

US20050263420A1 Device for collection, storage, retrieval and shipping of hair follicles from animals 有权
标题翻译：从动物收集，储存，检索和运送毛囊的装置
公开(公告)号：US20050263420A1
公开(公告)日：2005-12-01
申请号：US10857669
申请日：2004-05-29
申请人： Abraham Oommen
发明人： Abraham Oommen
IPC分类号： A61B10/00 , A61L15/00
CPC分类号： A61B10/0096
摘要： The present invention relates to a novel device for the collection, storage, shipping and retrieval of hair follicles from animals for the purpose of isolating DNA or other genetic material from the follicles for analysis. The device has outer flaps for the protection as well as identification of the samples and an inner part where samples are placed. The inner device has thicker base and a clear plastic cover, the easy peel back of which is facilitated by a) low tack adhesives that hold the two together and b) a touch cut on one end, through the base sheet which creates a grip. This makes the device convenient and easy to use, and yet a robust collection device for hair follicles from animals in a farm or real-life situation. Hair follicles can be punched out through the inner device for direct DNA isolation and analysis.
摘要翻译：本发明涉及一种用于从动物收集，储存，运送和回收毛囊的新型装置，用于从毛囊中分离DNA或其他遗传物质用于分析。该装置具有用于保护的外部翼片以及样品的识别以及放置样品的内部部件。内部装置具有较厚的基部和透明的塑料盖，其容易的剥离由以下方式促进：a）将两者夹在一起的低粘性粘合剂，以及b）一端的触摸切口，通过形成抓握的基片。这使得设备方便和易于使用，而且还具有强大的收集装置，用于在农场或现实生活中的动物的毛囊。可以通过内部装置冲洗毛囊直接进行DNA分离和分析。

5. 发明申请

US20110265582A1 Device for collection, storage, retrieval and shipping of hair follicles from animals 有权
标题翻译：从动物收集，储存，检索和运送毛囊的装置
公开(公告)号：US20110265582A1
公开(公告)日：2011-11-03
申请号：US13068239
申请日：2011-05-06
申请人： Abraham Oommen
发明人： Abraham Oommen
IPC分类号： G01N1/04
CPC分类号： A61B10/0096
摘要： The present invention relates to a novel device for the collection, storage, shipping and retrieval of hair follicles from animals for the purpose of isolating DNA or other genetic material from the follicles for analysis. The device has outer flaps for the protection as well as identification of the samples and an inner part where samples are placed. The inner device has thicker base and a clear plastic cover, the easy peel back of which is facilitated by a) low tack adhesives that hold the two together and b) a touch cut on one end, through the base sheet which creates a grip. This makes the device convenient and easy to use, and yet a robust collection device for hair follicles from animals in a farm or real-life situation. Hair follicles can be punched out through the inner device for direct DNA isolation and analysis.
摘要翻译：本发明涉及一种用于从动物收集，储存，运送和回收毛囊的新型装置，用于从毛囊中分离DNA或其他遗传物质用于分析。该装置具有用于保护的外部翼片以及样品的识别以及放置样品的内部部件。内部装置具有较厚的基部和透明的塑料盖，其容易的剥离由以下方式促进：a）将两者夹在一起的低粘性粘合剂，以及b）一端的触摸切口，通过形成抓握的基片。这使得设备方便和易于使用，而且还具有强大的收集装置，用于在农场或现实生活中的动物的毛囊。可以通过内部装置冲洗毛囊直接进行DNA分离和分析。

6. 发明授权

US08622215B2 Device for collection, storage, retrieval and shipping of hair follicles from animals 有权
标题翻译：从动物收集，储存，检索和运送毛囊的装置
公开(公告)号：US08622215B2
公开(公告)日：2014-01-07
申请号：US13068239
申请日：2011-05-06
申请人： Abraham Oommen
发明人： Abraham Oommen
IPC分类号： B65D73/00 , B65D81/02
CPC分类号： A61B10/0096
摘要： The present invention relates to a novel device for the collection, storage, shipping and retrieval of hair follicles from animals for the purpose of isolating DNA or other genetic material from the follicles for analysis. The device has outer flaps for the protection as well as identification of the samples and an inner part where samples are placed. The inner device has thicker base and a clear plastic cover, the easy peel back of which is facilitated by a) low tack adhesives that hold the two together and b) a touch cut on one end, through the base sheet which creates a grip. This makes the device convenient and easy to use, and yet a robust collection device for hair follicles from animals in a farm or real-life situation. Hair follicles can be punched out through the inner device for direct DNA isolation and analysis.
摘要翻译：本发明涉及一种用于从动物收集，储存，运送和回收毛囊的新型装置，用于从毛囊中分离DNA或其他遗传物质用于分析。该装置具有用于保护的外部翼片以及样品的识别以及放置样品的内部部件。内部装置具有较厚的基部和透明的塑料盖，其容易的剥离由以下方式促进：a）将两者保持在一起的低粘性粘合剂，以及b）一端的触摸切口，通过形成抓握的基片。这使得设备方便和易于使用，而且还具有强大的收集装置，用于在农场或现实生活中的动物的毛囊。可以通过内部装置冲洗毛囊直接进行DNA分离和分析。

7. 发明授权

US07470399B2 Device for collection, storage, retrieval and shipping of hair follicles from animals 有权
标题翻译：从动物收集，储存，检索和运送毛囊的装置
公开(公告)号：US07470399B2
公开(公告)日：2008-12-30
申请号：US10857669
申请日：2004-05-29
申请人： Abraham Oommen
发明人： Abraham Oommen
IPC分类号： B65D73/00 , B65D81/02
CPC分类号： A61B10/0096
摘要： The present invention relates to a novel device for the collection, storage, shipping and retrieval of hair follicles from animals for the purpose of isolating DNA or other genetic material from the follicles for analysis. The device has outer flaps for the protection as well as identification of the samples and an inner part where samples are placed. The inner device has thicker base and a clear plastic cover, the easy peel back of which is facilitated by a) low tack adhesives that hold the two together and b) a touch cut on one end, through the base sheet which creates a grip. This makes the device convenient and easy to use, and yet a robust collection device for hair follicles from animals in a farm or real-life situation. Hair follicles can be punched out through the inner device for direct DNA isolation and analysis.
摘要翻译：本发明涉及一种用于从动物收集，储存，运送和回收毛囊的新型装置，用于从毛囊中分离DNA或其他遗传物质用于分析。该装置具有用于保护的外部翼片以及样品的识别以及放置样品的内部部件。内部装置具有较厚的基部和透明的塑料盖，其容易的剥离由以下方式促进：a）将两者夹在一起的低粘性粘合剂，以及b）一端的触摸切口，通过形成抓握的基片。这使得设备方便和易于使用，而且还具有强大的收集装置，用于在农场或现实生活中的动物的毛囊。可以通过内部装置冲洗毛囊直接进行DNA分离和分析。

8. 发明授权

US5723298A Cycle labeling and sequencing with thermostable polymerases 失效
标题翻译：循环标记和用热稳定聚合酶测序
公开(公告)号：US5723298A
公开(公告)日：1998-03-03
申请号：US714562
申请日：1996-09-16
申请人： Abraham Oommen , Steve Roemer
发明人： Abraham Oommen , Steve Roemer
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6869
摘要： The present invention provides a novel method for labeling and sequencing nucleic acid molecules, particularly DNA molecules in which an internally labeled, partially extended primer is elongated in a cycled primer extension reaction. An unlabeled DNA primer is contacted with a DNA template in the presence of suboptimal amounts of four dNTPs, one of which is labeled with a detectable marker which may be a fluorescent or visible fluorophor, and infared fluorophor or a radioactive label. This small, labeled primer extension product is then transferred to a new reaction where chain terminated primer extension products for DNA analysis are prepared.
摘要翻译：本发明提供了用于标记和测序核酸分子的新方法，特别是在循环引物延伸反应中内部标记的部分延伸的引物伸长的DNA分子。在不适当数量的四种dNTP存在下，将未标记的DNA引物与DNA模板接触，其中一种用可检测的标记物标记，其可以是荧光或可见的荧光体，并且可以用荧光荧光标记或放射性标记进行标记。然后将这种小的标记的引物延伸产物转移到新的反应中，其中制备用于DNA分析的链终止引物延伸产物。

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