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1. 发明授权

US4137160A Device for separating low density material such as gas bubbles from a liquid, and the use thereof in a dialysis delivery system 失效
标题翻译：用于从液体中分离低密度材料如气泡的装置及其在透析递送系统中的用途
公开(公告)号：US4137160A
公开(公告)日：1979-01-30
申请号：US739878
申请日：1976-11-08
申请人： Wendell V. Ebling , Rene G. Lamadrid , Earl G. Phillips
发明人： Wendell V. Ebling , Rene G. Lamadrid , Earl G. Phillips
IPC分类号： A61M1/16 , B01D19/00 , B01D13/00
CPC分类号： B01D19/0057 , A61M1/1658 , B01D61/30
摘要： A device, which may be used in a dialysis system, is disclosed for separating low density material such as gas bubbles from a liquid by swirling the liquid, to cause the bubbles to migrate toward the center of the swirling liquid. A liquid storage chamber having side walls of generally circular cross-section of the longitudinal axis is provided. A port is provided for removing the bubbles or the like, positioned adjacent the longitudinal axis of the chamber. A liqud inlet passes into the chamber in such a position as to pass liquid into the chamber circumferentially about the side walls, to provide swirling of liquid passing into the chamber. In accordance with this invention, outlet means and pump means are provided for removing bubble-free liquid from the chamber at a point spaced from the inlet but adjacent the side wall. A first conduit conveys a portion of the bubble-free liquid so removed to a desired site of use, while a second conduit conveys the balance of the bubble-free liquid so removed back to the liquid inlet for reentry into the chamber, to enhance the swirling action of fluid in the chamber.
摘要翻译：公开了一种可用于透析系统中的装置，用于通过旋转液体从液体中分离诸如气泡的低密度材料，从而使气泡向旋转液体的中心迁移。提供具有纵向轴线的大致圆形横截面的侧壁的液体储存室。设置有用于除去邻近室的纵向轴线定位的气泡等的端口。液体入口进入腔室，使得液体沿着侧壁周向地进入腔室中，以提供通向腔室的液体旋转的位置。根据本发明，提供出口装置和泵装置，用于在与入口间隔开但邻近侧壁的点处从室中除去无气泡的液体。第一导管将一部分无气泡的液体输送到所需的使用位置，而第二导管将无气泡液体的平衡输送到液体入口以重新进入腔室，以增强流体在腔室中的旋动作用。

2. 发明授权

US4227420A Pressure coupling mechanism in a pressure monitoring assembly 失效
标题翻译：压力监测组件中的压力耦合机构
公开(公告)号：US4227420A
公开(公告)日：1980-10-14
申请号：US47568
申请日：1979-06-11
申请人： Rene G. Lamadrid
发明人： Rene G. Lamadrid
IPC分类号： A61B5/0215 , G01L7/08 , G01L19/00
CPC分类号： G01L7/08 , A61B5/0215 , G01L19/0023
摘要： The pressure monitoring assembly monitors changes in pressure of a fluid passing through the assembly. This is accomplished by passing a liquid through a pressure transfer device having first and second chambers therein separated by a flexible diaphragm. The first chamber has air therein and pressure changes are transmitted across the diaphragm from the second chamber through which the liquid flows. The assembly further includes a pressure transducer and a pressure coupling mechanism for coupling the pressure transfer device to the pressure transducer. The pressure coupling mechanism includes a body having a cylindrical chamber and a piston positioned for movement therein with a piston shaft protruding from a coupling end of the body. The shaft is biased outward from the coupling end of the body by a spring. The coupling end has an O ring seal which forms a seal with the pressure transfer device around an orifice in a wall of the second chamber when the pressure coupling mechanism is mounted to the pressure transfer device. The piston shaft has a through-bore to the cylindrical chamber so that air is trapped in an air passageway comprising the first chamber, the through-bore and the cylindrical chamber. As the pressure transfer device is latched to the pressure coupling mechanism, the shaft and piston are pushed against the spring toward the pressure transducer which is mounted to the body at one end of the cylindrical chamber thereby compressing the trapped air in the air passageway.
摘要翻译：压力监测组件监测通过组件的流体的压力变化。这是通过使液体通过其中由柔性隔膜分隔的第一和第二室的压力传递装置来实现的。第一腔室具有空气，压力变化通过隔膜从液体流过的第二腔室传播。组件还包括用于将压力传递装置耦合到压力传感器的压力传感器和压力耦合机构。压力联接机构包括具有圆柱形腔体的主体和定位成用于在其中移动的活塞，活塞轴从主体的联接端突出。轴通过弹簧从主体的联接端向外偏压。联接端具有O形密封件，当压力联接机构安装到压力传递装置时，O形密封件与压力传递装置围绕第二腔室壁的孔口形成密封。活塞轴具有通向圆柱形室的通孔，使得空气被捕获在包括第一室，通孔和圆筒室的空气通道中。当压力传递装置被锁定到压力联接机构时，轴和活塞被压靠弹簧推向压力传感器，压力传感器在圆柱形腔室的一端安装到主体，从而压缩空气通道中被捕获的空气。

3. 发明授权

US4087185A Blood leak detector 失效
标题翻译：血液检漏仪
公开(公告)号：US4087185A
公开(公告)日：1978-05-02
申请号：US588513
申请日：1975-06-19
申请人： Rene G. Lamadrid
发明人： Rene G. Lamadrid
IPC分类号： A61M1/16 , G01N21/85 , G01N21/26
CPC分类号： G01N21/85 , A61M1/1692
摘要： A detector of blood in dialyzing solution, which operates by measuring the optical density of the dialyzing solution, is prevented from improper indication arising from the presence of bubbles in the dialyzing solution, by shaping the fluid passages to channel the bubbles away from the optical sensing path.
摘要翻译：通过测量透析溶液的光密度进行操作的透析溶液中的血液检测器被防止透析溶液中存在气泡而引起的不适当的指示，通过使流体通道成形以使气泡远离光学感测路径。

4. 发明授权

US4256442A Improved pressure plate movement system for a peristaltic pump 失效
标题翻译：改进的蠕动泵压板运动系统
公开(公告)号：US4256442A
公开(公告)日：1981-03-17
申请号：US31140
申请日：1979-04-18
申请人： Rene G. Lamadrid , Herbert M. Cullis
发明人： Rene G. Lamadrid , Herbert M. Cullis
IPC分类号： F04B43/12 , F04B45/06
CPC分类号： F04B43/1284 , A61M5/14232
摘要： An improved peristaltic pump includes a pivotably mounted pressure plate which, together with the pump roller elements, defines the pump chamber. The pivotal mounting of the pressure plate facilitates accessibility to the pump chamber in order to simplify the pump tube loading and unloading procedures. The mounting system for the pressure plate includes a mechanically-advantaged four-bar linkage arrangement which automatically retains the pressure plate in either its fully open or fully closed position as a result of an over-center type locking construction. The pump also includes a mechanism for adjusting the volume flow rate characteristic of a pump tube. This is particularly adaptable for a dual-tube system wherein a predetermined volume flow rate ratio is to be achieved.
摘要翻译：改进的蠕动泵包括可枢转地安装的压力板，其与泵辊元件一起限定泵室。压力盘的枢转安装有助于泵室的可及性，以简化泵管的装载和卸载程序。用于压力板的安装系统包括机械优势的四杆联动装置，其由于过中型锁定结构而将压板自动保持在其完全打开或完全关闭位置。泵还包括用于调节泵管的体积流量特性的机构。这对于要实现预定体积流量比的双管系统特别适用。

5. 发明授权

US4283004A Vibration attenuation support assembly for a centrifugal liquid processing apparatus 失效
标题翻译：用于离心液体处理设备的振动衰减支撑组件
公开(公告)号：US4283004A
公开(公告)日：1981-08-11
申请号：US66576
申请日：1979-08-15
申请人： Rene G. Lamadrid
发明人： Rene G. Lamadrid
IPC分类号： B01D21/26 , B04B5/04 , B01D43/00
CPC分类号： B04B5/0442 , B01D21/262 , B01D2221/08 , B01D2221/10
摘要： The vibration attenuation support assembly is utilized in a centrifugal liquid processing apparatus for supporting a rotor assembly, a non-rotatable arm fixed to and forming part of the support assembly and a prime mover and for attenuating vibrations created by an unbalanced mass in the rotating parts of the apparatus. The apparatus comprises a cabinet having sidewalls and a floor and a rotor assembly mounted on the support assembly mounted on the floor. Tubings are coupled directly between a source of the liquid outside of the rotor to receptacles within the rotor without the use of fluid seals and are supported from the stationary arm. The rotor assembly includes structure for guiding the tubings from the stationary arm to the rotor and a drive train mechanism and prime mover for rotating the tubings at a first speed and for rotating the rotor at a second speed twice the first speed. The support assembly includes a weldment for supporting the rotor assembly and prime mover and includes four elastomeric members for mounting the weldment on the floor. The support assembly has a mass greater than the unbalanced mass and in one embodiment the support assembly together with the rotor assembly and prime mover have a mass of approximately 150 kilograms and the unbalanced mass is 30 grams acting at a radius of 5 inches at a rotation of 1400 revolutions per minute.
摘要翻译：振动衰减支持组件用于离心液体处理装置中，用于支撑转子组件，固定到支撑组件的一部分上的不可旋转的臂和原动机，并且用于衰减由旋转部件中的不平衡质量产生的振动的装置。该装置包括具有侧壁和底板的壳体和安装在安装在地板上的支撑组件上的转子组件。管道直接连接在转子外部的液体源与转子内的容器之间，而不使用流体密封件，并从固定臂支撑。转子组件包括用于将管道从固定臂引导到转子的结构，以及用于以第一速度旋转管道并且以第二速度以第二速度旋转转子的传动系机构和原动机。支撑组件包括用于支撑转子组件和原动机的焊件，并且包括用于将焊件安装在地板上的四个弹性部件。支撑组件具有大于不平衡质量的质量，并且在一个实施例中，支撑组件与转子组件和原动机一起具有大约150千克的质量，并且不平衡质量为30克，在旋转时以5英寸的半径作用每分钟1400转。

6. 发明授权

US4227814A Optical density detector 失效
标题翻译：光密度检测器
公开(公告)号：US4227814A
公开(公告)日：1980-10-14
申请号：US8274
申请日：1979-02-01
申请人： Charles Soodak , Rene G. Lamadrid , David Lohr
发明人： Charles Soodak , Rene G. Lamadrid , David Lohr
IPC分类号： A61M1/16 , A61M1/36 , B04B5/04 , B04B13/00 , G01N21/03 , G01N21/85
CPC分类号： G01N21/85 , A61M1/1692 , A61M1/3696 , B04B13/00 , B04B5/0442 , A61M2205/3313 , G01N2021/0364
摘要： The optical detector is particularly adapted for use with an apparatus for separating blood into its components and is of the type including a centrifuge for centrifuging whole blood to separate same into the components thereof and of the type wherein plasma is withdrawn from the centrifuge through a flexible, light transmitting tubing and the spillover of red blood cells into the plasma withdrawn is monitored by the optical detector. The optical detector comprises a block having a slot across the top face thereof, the inner portion of the slot having a width less than the outer diameter of the tubing which is received in the slot such that when the tubing is pressed into the slot, it is squeezed from a circular cross section to an oval cross section to present two flat portions of the tubing adjacent opposite sidewalls of the slot. A first cavity is situated in the block behing a first sidewall of the slot and a second cavity is situated in the block behind a second sidewall of the slot. Apertures are provided in the sidewalls and light from a light source is directed along the axis of the apertures, through lenses in the cavities which seal the cavities from the slot and through the tubing in the slot from the first cavity to the second cavity where a photosensor is located. The photosensor is operable to generate an electrical signal which is indicative of the light sensed and which can be utilized for measuring the optical density of the plasma flowing through the tubing.
摘要翻译：光学检测器特别适用于将血液分离成其组分的装置，其类型包括用于离心全血以将其分离成其组分的离心机，以及其中通过柔性的离心机将血浆从离心机中取出的类型，透光管和红血细胞溢出进入血浆，由光学检测器监测。光学检测器包括具有横跨其顶面的槽的块，槽的内部部分具有小于容纳在槽中的管道的外径的宽度，使得当管道被压入槽中时从圆形横截面挤压到椭圆形横截面，以呈现与狭槽相对侧壁相邻的管道的两个平坦部分。第一腔位于所述块中，所述槽中的所述槽的第一侧壁和第二腔位于所述槽的后面的所述槽的第二侧壁的后面。在侧壁中提供孔径，并且来自光源的光线沿着孔的轴线被引导通过空腔中的透镜，其将空腔从狭缝密封并且通过槽中的管道从第一腔体到第二腔室，其中光电传感器位于。光传感器可操作以产生指示所感测的光并且可用于测量流过管道的等离子体的光密度的电信号。

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