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1. 发明授权

US07079620B2 Method and apparatus for determining a magnification factor a radiographic image 有权
公开(公告)号：US07079620B2
公开(公告)日：2006-07-18
申请号：US10099698
申请日：2002-03-13
申请人： Regis Vaillant , Franciso Sureda , Jean Lienard
发明人： Regis Vaillant , Franciso Sureda , Jean Lienard
IPC分类号： A61B6/02 , G03C9/00
CPC分类号： A61B6/504 , A61B5/1075 , A61B6/588 , A61B6/589
摘要： A method and apparatus for determining a magnification factor in a radiography device of the type comprising an X-ray source and means for acquiring images placed facing the source, the source and the means for acquiring images being mounted so as to rotate about at least one axis with respect to a support on which an object to be X-rayed is intended to be positioned. The method and the apparatus implementing the method comprises: acquiring at least two images corresponding to two different angular positions of the source and of the recording means with respect to the support; identifying on these images projections of at least one point of the X-rayed object; and determining the magnification factor of at least one of the images, first, as a function of the angular displacement of the source and of the recording means between the acquisitions of the images in question and, secondly, as a function of the positions on these images of the identified projections.

2. 发明申请

US20090022376A1 METHOD FOR PROCESSING IMAGES IN INTERVENTIONAL RADIOSCOPY TO DETECT GUIDING INSTRUMENTATION EQUIPMENT 有权
标题翻译：用于检测导引仪器设备的传统放射线图像处理方法
公开(公告)号：US20090022376A1
公开(公告)日：2009-01-22
申请号：US12139579
申请日：2008-06-16
申请人： Vincent Bismuth , Vincent Auvray , Jean Lienard , Regis Vaillant
发明人： Vincent Bismuth , Vincent Auvray , Jean Lienard , Regis Vaillant
IPC分类号： G06K9/00
CPC分类号： G06T5/20 , G06K9/4609 , G06K2209/057
摘要： A method for processing images in interventional radioscopy for detecting guiding instrumentation equipment. The method of the invention enables objects of longilinear or very curved shapes to be detected within the radioscopic image having very low contrast to noise ratios. In one embodiment, an algorithm enables the measured contrast to noise ratio of long or curved structures in the image to be considerably improved. To do this, an embodiment of the invention uses oriented, separable, recursive and rapid steerable detection filters. Said detection filters have a low calculation cost, even for long filters having several orientations
摘要翻译：用于检测导向仪器设备的介入式放射检查图像处理方法。本发明的方法能够在具有非常低的对比度噪声比的放射线图像内检测到具有长线形或非常弯曲形状的物体。在一个实施例中，算法使得能够显着改善图像中的长或弯曲结构的测量对比度与噪声比。为此，本发明的实施例使用定向的，可分离的，递归的和快速的可操纵的检测滤波器。所述检测滤波器具有低的计算成本，即使对于具有多个取向的长滤波器也是如此

3. 发明授权

US07440790B2 Method and apparatus for monitoring cardiac activity 有权
标题翻译：用于监测心脏活动的方法和装置
公开(公告)号：US07440790B2
公开(公告)日：2008-10-21
申请号：US11114378
申请日：2005-04-26
申请人： Jean Lienard , Regis Vaillant
发明人： Jean Lienard , Regis Vaillant
IPC分类号： A61B5/05 , A61B6/00 , A61B5/02 , G06K9/00 , G01N23/04
CPC分类号： A61B5/1128 , A61B5/024 , G06T7/20 , G06T2207/30048
摘要： A method and apparatus for monitoring cardiac activity starting from a series of images of the heart made by X-rays. Attenuation of the X-rays is sampled on an area subject to repetitive thickenings of at least one wall of the heart, and a repetitive attenuation signal is interpreted as a signal representative of the heart activity.
摘要翻译：从X射线制成的心脏系列图像开始的心脏活动监测方法和装置。在经受至少一个心脏壁的重复增厚的区域上采样X射线的衰减，并且重复的衰减信号被解释为表示心脏活动的信号。

4. 发明申请

US20110019878A1 SYSTEM AND METHOD TO COMPENSATE FOR RESPIRATORY MOTION IN ACQUIRED RADIOGRAPHY IMAGES 有权
标题翻译：补偿放射影像中呼吸运动的系统和方法
公开(公告)号：US20110019878A1
公开(公告)日：2011-01-27
申请号：US12508070
申请日：2009-07-23
申请人： Elisabeth Soubelet , Jean Lienard , Regis Vaillant
发明人： Elisabeth Soubelet , Jean Lienard , Regis Vaillant
IPC分类号： G06T7/00 , G06T7/20
CPC分类号： A61B6/466 , A61B5/7285 , A61B6/503 , A61B6/5247 , A61B6/5264 , A61B6/5288 , A61B6/541 , A61B8/5276 , A61B8/543 , A61B2017/00699 , A61B2034/2065 , G06T7/246 , G06T2207/30048
摘要： A system and method to compensate for respiratory motion in imaging of instruments introduced into the subject anatomy is provided. The system can include an imaging system in communication with a controller. The controller can include a memory with program instructions for execution by the processor to perform the steps of: detecting an illustration of at least a portion of the plurality of instruments introduced into the subject anatomy in a first image and a second image, comparing and calculating a displacement of the plurality of instruments between the first and second images, calculating one of an average or median displacement of the plurality of instruments between the first and second images, and applying one of the average and the median displacement to adjust at least a portion of the first or second images or a pre-acquired three-dimensional model of the internal region of
摘要翻译：提供了一种用于补偿引入到主题解剖结构中的仪器的成像中的呼吸运动的系统和方法。该系统可以包括与控制器通信的成像系统。控制器可以包括具有程序指令的存储器，用于由处理器执行以执行以下步骤：检测在第一图像和第二图像中引入到主题解剖结构中的多个乐器的至少一部分的图示，比较和计算在所述第一和第二图像之间移动所述多个乐器，计算所述第一和第二图像之间的所述多个乐器的平均或中间位移之一，并且应用所述平均和所述中间位移之一来调整至少一部分的第一或第二图像或内部区域的预先获取的三维模型

5. 发明授权

US07734328B2 System and method to enhance visualization of an object in a vascular vessel 失效
标题翻译：用于增强血管中物体可视化的系统和方法
公开(公告)号：US07734328B2
公开(公告)日：2010-06-08
申请号：US11614209
申请日：2006-12-21
申请人： Regis Vaillant , Jean Lienard , Vincent Bismuth
发明人： Regis Vaillant , Jean Lienard , Vincent Bismuth
IPC分类号： A61B5/05
CPC分类号： A61B6/12 , G06T7/00
摘要： An imaging system of an object in an imaged subject is provided. The imaging system includes an image detector and a guidewire in support of a pair of markers. The imaging system also includes a controller in communication with the image detector. The controller includes a processor in communication to execute a series of programmable instructions stored in a memory, the programmable instructions including acquiring a plurality of acquired images, detecting a position of the pair of markers, calculating a first mathematical representation of an alignment of the guidewire between the markers and a second mathematical representation of an alignment of the guidewire not between the markers, and registering the first and second mathematical representations of the guidewire extending through the object relative to more than one of the acquired images so as to locate the object in at least one of the acquired images.
摘要翻译：提供了成像对象中的对象的成像系统。成像系统包括图像检测器和支撑一对标记的导丝。成像系统还包括与图像检测器通信的控制器。控制器包括处理器，其通信以执行存储在存储器中的一系列可编程指令，所述可编程指令包括获取多个获取的图像，检测所述一对标记的位置，计算所述导丝对准的第一数学表示在所述标记之间和所述导丝的对准的第二数学表示之间，而不是在所述标记之间，并且相对于多于一个所获取的图像登记延伸穿过所述对象的所述导丝的所述第一和第二数学表示，以将所述对象定位在所获取的图像中的至少一个。

6. 发明申请

US20080154122A1 SYSTEM AND METHOD TO ENHANCE VISUALIZATION OF AN OBJECT IN A VASCULAR VESSEL 失效
标题翻译：一种用于增强血管中物体可视化的系统和方法
公开(公告)号：US20080154122A1
公开(公告)日：2008-06-26
申请号：US11614209
申请日：2006-12-21
申请人： Regis Vaillant , Jean Lienard , Vincent Bismuth
发明人： Regis Vaillant , Jean Lienard , Vincent Bismuth
IPC分类号： A61B5/05
CPC分类号： A61B6/12 , G06T7/00
摘要： An imaging system of an object in an imaged subject is provided. The imaging system includes an image detector and a guidewire in support of a pair of markers. The imaging system also includes a controller in communication with the image detector. The controller includes a processor in communication to execute a series of programmable instructions stored in a memory, the programmable instructions including acquiring a plurality of acquired images, detecting a position of the pair of markers, calculating a first mathematical representation of an alignment of the guidewire between the markers and a second mathematical representation of an alignment of the guidewire not between the markers, and registering the first and second mathematical representations of the guidewire extending through the object relative to more than one of the acquired images so as to locate the object in at least one of the acquired images.
摘要翻译：提供了成像对象中的对象的成像系统。成像系统包括图像检测器和支撑一对标记的导丝。成像系统还包括与图像检测器通信的控制器。控制器包括处理器，其通信以执行存储在存储器中的一系列可编程指令，所述可编程指令包括获取多个获取的图像，检测所述一对标记的位置，计算所述导丝对准的第一数学表示在所述标记之间和所述导丝的对准的第二数学表示之间，而不是在所述标记之间，并且相对于多于一个所获取的图像登记延伸穿过所述对象的所述导丝的所述第一和第二数学表示，以将所述对象定位在所获取的图像中的至少一个。

7. 发明授权

US08233688B2 Method of detection and compensation for respiratory motion in radiography cardiac images synchronized with an electrocardiogram signal 有权
标题翻译：与心电图信号同步的放射照相心脏图像中呼吸运动的检测和补偿方法
公开(公告)号：US08233688B2
公开(公告)日：2012-07-31
申请号：US12054989
申请日：2008-03-25
申请人： Elisabeth Soubelet , Jean Lienard , Laurence Gavit-Houdant , Regis Vaillant
发明人： Elisabeth Soubelet , Jean Lienard , Laurence Gavit-Houdant , Regis Vaillant
IPC分类号： A61B6/00 , G06K9/00
CPC分类号： A61B6/12 , A61B5/7289 , A61B6/032 , A61B6/503 , A61B6/5217 , A61B6/5235 , A61B6/541 , A61B8/5238 , G01R33/48 , G01R33/4812 , G01R33/56509 , G01R33/5673
摘要： A method of detection and compensation for respiratory motion improves the registration between a 3D pre-operation image and X-ray images acquired during a cardiac intervention. By synchronizing the X-ray images with the electrocardiogram, the disclosed method thus eliminates the motion related to the heart cycle from these images, thus isolating the contribution of the respiratory motion. From this point, an algorithm is proposed capable of attributing the motion remaining in the radiography images to respiration. The algorithm also enables this motion to be detected and compensated for in order to obtain a registration between 3D cardiac images and radiography images.
摘要翻译：呼吸运动的检测和补偿方法改善了3D预处理图像与在心脏干预期间获取的X射线图像之间的配准。通过使X射线图像与心电图同步，所公开的方法从而消除了与这些图像相关的心脏周期运动，从而隔离了呼吸运动的贡献。从这一点上，提出了一种能够将放射摄影图像中剩余的运动归因于呼吸的算法。该算法还使得能够检测和补偿该运动，以便获得3D心脏图像和放射摄影图像之间的配准。

8. 发明申请

US20100208973A1 RADIOLOGICAL IMAGING METHOD AND DEVICE 审中-公开
标题翻译：放射成像方法和装置
公开(公告)号：US20100208973A1
公开(公告)日：2010-08-19
申请号：US12706004
申请日：2010-02-16
申请人： Jean Lienard , Regis Vaillant , Benoit Leny , Pierre-Luc Georgy
发明人： Jean Lienard , Regis Vaillant , Benoit Leny , Pierre-Luc Georgy
IPC分类号： G06K9/00 , G21K4/00
CPC分类号： A61B6/504 , A61B6/12 , A61B6/481 , A61B6/5235 , G06T5/50
摘要： A method for radiological imaging of a region of interest including blood vessels. The method has the steps of acquiring a real-time fluoroscopic image of the region of interest by exposing the region of interest to a first dose of X-rays, the fluoroscopic image showing background structures and instrument introduced into the vessels; subtracting a mask image from the acquired real-time fluoroscopic image to generate a subtracted fluoroscopic image showing only the instrument; combining the subtracted fluoroscopic image and a pre-recorded diagnostic image of the region of interest showing only the blood vessels to generate a combined image showing both the blood vessels and the instrument; and displaying the combined image on a screen for viewing. The mask image is determined from a fluoroscopic image acquired prior to the introduction of the instrument into the vessels by exposing the region to an X-ray does equivalent to the first dose.
摘要翻译：一种用于包括血管在内的感兴趣区域的放射成像的方法。该方法具有以下步骤：通过将感兴趣区域暴露于第一剂量的X射线，透视图像显示背景结构和引入血管的仪器来获取感兴趣区域的实时透视图像; 从获取的实时透视图像中减去掩模图像，以产生仅显示仪器的减去的透视图像; 将减去的透视图像和仅显示血管的感兴趣区域的预先记录的诊断图像组合以产生显示出血管和仪器的组合图像; 并在屏幕上显示组合图像以供观看。掩模图像是通过将该区域暴露于与第一剂量相当的X射线确定之前，从将仪器引入血管之前获得的透视图像来确定的。

9. 发明申请

US20050288570A1 Method and apparatus for monitoring cardiac activity 有权
标题翻译：用于监测心脏活动的方法和装置
公开(公告)号：US20050288570A1
公开(公告)日：2005-12-29
申请号：US11114378
申请日：2005-04-26
申请人： Jean Lienard , Regis Vaillant
发明人： Jean Lienard , Regis Vaillant
IPC分类号： A61B5/024 , A61B5/05 , A61B5/11 , G06T7/00 , G06T7/20
CPC分类号： A61B5/1128 , A61B5/024 , G06T7/20 , G06T2207/30048
摘要： A method and apparatus for monitoring cardiac activity starting from a series of images of the heart made by X-rays. Attenuation of the X-rays is sampled on an area subject to repetitive thickenings of at least one wall of the heart, and a repetitive attenuation signal is interpreted as a signal representative of the heart activity.
摘要翻译：从X射线制成的心脏系列图像开始的心脏活动监测方法和装置。在经受至少一个心脏壁的重复增厚的区域上采样X射线的衰减，并且重复的衰减信号被解释为表示心脏活动的信号。

10. 发明授权

US08718338B2 System and method to compensate for respiratory motion in acquired radiography images 有权
标题翻译：补偿摄影图像中呼吸运动的系统和方法
公开(公告)号：US08718338B2
公开(公告)日：2014-05-06
申请号：US12508070
申请日：2009-07-23
申请人： Elisabeth Soubelet , Jean Lienard , Regis Vaillant
发明人： Elisabeth Soubelet , Jean Lienard , Regis Vaillant
IPC分类号： G06K9/00 , A61B5/05 , A61B6/00 , G01N23/00 , A61B6/08
CPC分类号： A61B6/466 , A61B5/7285 , A61B6/503 , A61B6/5247 , A61B6/5264 , A61B6/5288 , A61B6/541 , A61B8/5276 , A61B8/543 , A61B2017/00699 , A61B2034/2065 , G06T7/246 , G06T2207/30048
摘要： A system and method to compensate for respiratory motion in imaging of instruments introduced into the subject anatomy is provided. The system can include an imaging system in communication with a controller. The controller can include a memory with program instructions for execution by the processor to perform the steps of: detecting an illustration of at least a portion of the plurality of instruments introduced into the subject anatomy in a first image and a second image, comparing and calculating a displacement of the plurality of instruments between the first and second images, calculating one of an average or median displacement of the plurality of instruments between the first and second images, and applying one of the average and the median displacement to adjust at least a portion of the first or second images or a pre-acquired three-dimensional model of the internal region of interest.
摘要翻译：提供了一种用于补偿引入到主题解剖结构中的仪器的成像中的呼吸运动的系统和方法。该系统可以包括与控制器通信的成像系统。控制器可以包括具有程序指令的存储器，用于由处理器执行以执行以下步骤：检测在第一图像和第二图像中引入到主题解剖结构中的多个乐器的至少一部分的图示，比较和计算在所述第一和第二图像之间移动所述多个乐器，计算所述第一和第二图像之间的所述多个乐器的平均或中间位移之一，并且应用所述平均和所述中间位移之一来调整至少一部分的第一或第二图像或所感兴趣的内部区域的预先获取的三维模型。

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