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1. 发明授权

US5757006A Articulating detector array for a gamma camera 失效
标题翻译：用于伽马相机的铰接式探测器阵列
公开(公告)号：US5757006A
公开(公告)日：1998-05-26
申请号：US790833
申请日：1997-01-30
申请人： Raymond P. DeVito , James J. Hamill
发明人： Raymond P. DeVito , James J. Hamill
IPC分类号： G01T1/164 , G01T1/24 , G01T1/161
CPC分类号： G01T1/1642 , G01T1/249 , A61B6/037
摘要： An articulating detector array for gamma cameras is disclosed which is adaptable to perform different imaging techniques in a single apparatus. The articulating detector array is adapted to detect incident gamma radiation from diverse directions as well as Compton scattering thereof without the need of a collimator, as so has improved gamma ray detection efficiency. The detector array includes radiation detectors in an array and movable to a plurality of positions, in which each radiation detector is responsive to gamma radiation from a target for generating detection signals for use in tomographic imaging of the source. The detector array includes articulating support structures for mounting the detectors to the base and for moving the detectors from a first position to a second position. In one embodiment, the articulating support structures includes a first portion connected to a detector; and a second portion connected to the base, in which the first portion is adapted to extend from the second portion from the first position to the second position. In another embodiment, the articulating support structures include a pivot for pivotably mounting the detectors and for rotating the detectors from a first position to a second position.
摘要翻译：公开了一种用于伽马照相机的关节式检测器阵列，其适用于在单个装置中执行不同的成像技术。铰接检测器阵列适于从不同方向检测入射伽马射线以及其康普顿散射，而不需要准直器，因此伽马射线检测效率得到改善。检测器阵列包括阵列中的辐射检测器并且可移动到多个位置，其中每个辐射检测器响应来自目标的伽马射线，用于产生用于源的断层成像的检测信号。检测器阵列包括用于将检测器安装到基座并用于将检测器从第一位置移动到第二位置的铰接支撑结构。在一个实施例中，铰接支撑结构包括连接到检测器的第一部分; 以及连接到所述基座的第二部分，其中所述第一部分适于从所述第二部分从所述第一位置延伸到所述第二位置。在另一个实施例中，铰接支撑结构包括用于可枢转地安装检测器并用于将检测器从第一位置转动到第二位置的枢轴。

2. 发明授权

US5376797A Method and apparatus for producing and utilizing flashes of light which simulate scintillation events 失效
标题翻译：用于产生和利用模拟闪烁事件的闪光灯的方法和装置
公开(公告)号：US5376797A
公开(公告)日：1994-12-27
申请号：US116656
申请日：1993-09-03
申请人： Dennis E. Persyk , Raymond P. DeVito
发明人： Dennis E. Persyk , Raymond P. DeVito
IPC分类号： G01T1/164 , G01D18/00 , G01T1/208 , G01T1/40
CPC分类号： G01T1/208 , G01D18/00 , G01T1/40
摘要： Light emitting diodes (LEDs) at fixed locations are placed at the entrance face of the scintillator within the detector head of a scintillation camera system. By energizing the LEDs, surrogate scintillation events may be generated and processed by the scintillation camera system. Information thus acquired can be used to maintain the photodetectors in a well-tuned state, to identify baseline shifts in the preamplifier channels and to determine system deadtime.
摘要翻译：固定位置处的发光二极管（LED）位于闪烁照相机系统的检测器头部内的闪烁器的入射面。通过激励LED，可以由闪烁照相机系统产生和处理替代闪烁事件。如此获得的信息可用于将光电探测器维持在良好调谐状态，以识别前置放大器通道中的基线偏移并确定系统死区时间。

3. 发明申请

US20120053847A1 SUPPRESSED CORRELATION METHOD FOR IDENTIFYING RADIOACTIVE SOURCES 失效
标题翻译：用于识别放射源的抑制相关方法
公开(公告)号：US20120053847A1
公开(公告)日：2012-03-01
申请号：US13292755
申请日：2011-11-09
申请人： Raymond P. DeVito , Timothy E. Doyle
发明人： Raymond P. DeVito , Timothy E. Doyle
IPC分类号： G06F19/00
CPC分类号： G01T1/1647 , G01T1/167 , G01T7/00 , G01V5/0091
摘要： A radiation detection, localization, and identification system uses a searching algorithm to identify hypothetical solutions to Compton scatter data. Model based representations of the physical data collection yield the location of radiation sources when suppressed correlations of source location are identified in processed event data. The system's detector is an array of radiation detectors networked to act as a single detection system. This network has wide area of view and high sensitivity to radiation sources since no collimation is required.
摘要翻译：辐射检测，定位和识别系统使用搜索算法来识别康普顿散射数据的假设解。在处理的事件数据中识别出源位置的抑制相关性时，物理数据收集的基于模型的表示产生辐射源的位置。该系统的检测器是一组辐射检测器，网络化，用作单个检测系统。该网络具有广阔的视野和对辐射源的高灵敏度，因为不需要准直。

4. 发明授权

US5249124A Multi-isotope imaging using energy-weighted acquisition for, e.g., myocardial perfusion studies 失效
标题翻译：多重同位素成像使用能量加权获取，E.G.，MYOCARDIAL PERFUSION STUDIES
公开(公告)号：US5249124A
公开(公告)日：1993-09-28
申请号：US685940
申请日：1991-04-16
申请人： Raymond P. DeVito
发明人： Raymond P. DeVito
IPC分类号： G01T1/164
CPC分类号： G01T1/1642 , A61B6/4258 , A61B6/037
摘要： A multi-isotope study is carried out using a plurality of imaging agents which are imaged simultaneously. The information obtained is weighted using as many energy weighting functions as there are isotopes. The weighting reduces "crosstalk" between each of the single-isotope images which are produced as a result of the study. This produces improved results in, for example, dual-isotope (Tc-99m and Tl-201) myocardial perfusion studies.
摘要翻译：使用同时成像的多个成像剂进行多同位素研究。所获得的信息使用与同位素一样多的能量加权函数进行加权。加权减少了作为研究结果产生的每个单同位素图像之间的“串扰”。这在例如双重同位素（Tc-99m和T1-1201）心肌灌注研究中产生改善的结果。

5. 发明申请

US20090256080A1 IDENTIFICATION AND LOCALIZATION OF RADIOISOTOPES 失效
标题翻译：识别和定位放射性物质
公开(公告)号：US20090256080A1
公开(公告)日：2009-10-15
申请号：US12436987
申请日：2009-05-07
申请人： Raymond P. DeVito
发明人： Raymond P. DeVito
IPC分类号： G01T1/20 , G01T1/24
CPC分类号： G01T1/167 , G01T1/1642 , G01T1/1644 , G01T1/2985 , G01T7/00
摘要： A radiation detection, localization, and identification system uses a searching algorithm to identify geometric correlation of hypothetical solutions to Compton Imaging. Geometric correlation of correct associations of gamma ray energies with each detected event yields the identity and location of radiation sources. The system's detector is an array of radiation detectors networked to act as a single detection system. This network has wide area of view and high sensitivity to radiation sources since no collimation is required.
摘要翻译：辐射检测，定位和识别系统使用搜索算法来识别假想解决方案对康普顿成像的几何相关性。伽马射线能量与每个检测到的事件的正确关联的几何相关性产生辐射源的身份和位置。该系统的检测器是一组辐射检测器，网络化，用作单个检测系统。该网络具有广阔的视野和对辐射源的高灵敏度，因为不需要准直。

6. 发明授权

US06242743B1 Non-orbiting tomographic imaging system 失效
标题翻译：非轨道断层成像系统
公开(公告)号：US06242743B1
公开(公告)日：2001-06-05
申请号：US09132331
申请日：1998-08-11
申请人： Raymond P. DeVito , Edward J. Haines , James R. Domnanovich
发明人： Raymond P. DeVito , Edward J. Haines , James R. Domnanovich
IPC分类号： G01T1166
CPC分类号： A61B6/037 , A61B6/027 , A61B6/502 , A61B6/541 , G01T1/2985
摘要： A tomographic imaging system which images ionizing radiation such as gamma rays or x rays and which: 1) can produce tomographic images without requiring an orbiting motion of the detector(s) or collimator(s) around the object of interest, 2) produces smaller tomographic systems with enhanced system mobility, and 3) is capable of observing the object of interest from sufficiently many directions to allow multiple time-sequenced tomographic images to be produced. The system consists of a plurality of detector modules which are distributed about or around the object of interest and which fully or partially encircle it. The detector modules are positioned close to the object of interest thereby improving spatial resolution and image quality. The plurality of detectors view a portion of the patient or object of interest simultaneously from a plurality of positions. These attributes are achieved by configuring small modular radiation detector with high-resolution collimators in a combination of application-specific acquisition geometries and non-orbital detector module motion sequences composed of tilting, swiveling and translating motions, and combinations of such motions. Various kinds of module geometry and module or collimator motion sequences are possible, and several combinations of such geometry and motion are shown. The geometric configurations may be fixed or variable during the acquisition or between acquisition intervals. Clinical applications of various embodiments of the tomography invention include imaging of the human heart, breast, brain or limbs, or small animals. Methods of using the non-orbiting tomographic imaging system are also included.
摘要翻译：对诸如γ射线或X射线的电离辐射进行成像的断层图像成像系统，其能够产生断层图像，而不需要感兴趣物体周围的检测器或准直器的轨道运动，2）产生较小的具有增强的系统移动性的断层摄影系统，以及3）能够从足够多的方向观察感兴趣的对象，以允许产生多个时间序列的断层摄影图像。该系统由多个检测器模块组成，其分布在感兴趣对象周围或周围，并且完全或部分地环绕它。检测器模块靠近感兴趣的对象定位，从而提高空间分辨率和图像质量。多个检测器从多个位置同时观察患者或感兴趣物体的一部分。这些属性是通过配置具有高分辨率准直器的小型模块化辐射探测器来实现的，其中应用特定采集几何结构和由倾斜，旋转和平移运动以及这些运动的组合组成的非轨道探测器模块运动序列。各种模块几何和模块或准直器运动顺序是可能的，并且示出了这种几何和运动的几种组合。在采集期间或采集间隔期间，几何配置可以是固定的或可变的。断层摄影发明的各种实施例的临床应用包括人心，乳房，脑或四肢或小动物的成像。还包括使用非轨道断层成像系统的方法。

7. 发明授权

US4780823A Multiple pixel area-weighted acquisition system for scintillation cameras 失效
标题翻译：用于闪烁照相机的多像素区域加权采集系统
公开(公告)号：US4780823A
公开(公告)日：1988-10-25
申请号：US838509
申请日：1986-03-11
申请人： Everett W. Stoub , Raymond P. DeVito , Anthony Del Medico
发明人： Everett W. Stoub , Raymond P. DeVito , Anthony Del Medico
IPC分类号： G01T1/164 , G01T1/20
CPC分类号： G01T1/1647 , G01T1/1642
摘要： Upon the detection of a scintillation event at an event pixel, a plurality of associated pixels are identified. Weights are assigned to the event pixel and to all of the associated pixels in such a manner as to attribute the event over an area in a statistically accurate manner. A current sum of all weights which have been previously assigned to each pixel is stored. Unblank signals are generated, based upon this current sum, and the current sum is updated to account for the number of unblank signals so generated.
摘要翻译：当在事件像素处检测到闪烁事件时，识别出多个相关联的像素。权重被分配给事件像素和所有相关联的像素，以便以统计学准确的方式将事件归属于区域。存储先前分配给每个像素的所有权重的当前和。基于该当前和产生Unblank信号，并且更新当前和以考虑如此生成的非空白信号的数量。

8. 发明授权

US08053735B2 Optimized case specific SPECT sampling 失效
标题翻译：优化案例特定SPECT采样
公开(公告)号：US08053735B2
公开(公告)日：2011-11-08
申请号：US12340101
申请日：2008-12-19
申请人： Raymond P. DeVito , Timothy Edwin Doyle
发明人： Raymond P. DeVito , Timothy Edwin Doyle
IPC分类号： G01T1/166
CPC分类号： G01T1/00
摘要： A method for improving single photon emission computed tomography by controlling acquisition parameters specific to the imaging goals and specific to the individual case under study. Data acquisition is modulated by scanning to adapt to the particular signal to noise characteristics of each object. A preliminary acquisition quickly scans the object of interest. The preliminary data is analyzed to optimize the secondary scan. The secondary scan is then acquired with optimized sampling of the object based on its own particular image characteristics. The system is able to learn, incorporating site specific data into a triaging set.
摘要翻译：通过控制成像目标特有的获取参数并针对正在研究的个别案例，改进单光子发射计算机断层扫描的方法。通过扫描调制数据采集，以适应每个物体的特定信噪比特性。初步采购可以快速扫描感兴趣的对象。分析初步数据以优化二次扫描。然后基于其自己的特定图像特征对对象的优化采样来获取二次扫描。系统能够学习，将站点特定的数据合并到一个分类组中。

9. 发明授权

US07897932B2 Identification and localization of radioisotopes 失效
标题翻译：鉴定和定位放射性同位素
公开(公告)号：US07897932B2
公开(公告)日：2011-03-01
申请号：US12436987
申请日：2009-05-07
申请人： Raymond P. DeVito
发明人： Raymond P. DeVito
IPC分类号： G01T1/20
CPC分类号： G01T1/167 , G01T1/1642 , G01T1/1644 , G01T1/2985 , G01T7/00
摘要： A radiation detection, localization, and identification system uses a searching algorithm to identify geometric correlation of hypothetical solutions to Compton Imaging. Geometric correlation of correct associations of gamma ray energies with each detected event yields the identity and location of radiation sources. The system's detector is an array of radiation detectors networked to act as a single detection system. This network has wide area of view and high sensitivity to radiation sources since no collimation is required.
摘要翻译：辐射检测，定位和识别系统使用搜索算法来识别假想解决方案对康普顿成像的几何相关性。伽马射线能量与每个检测到的事件的正确关联的几何相关性产生辐射源的身份和位置。该系统的检测器是一组辐射检测器，网络化，用作单个检测系统。该网络具有广阔的视野和对辐射源的高灵敏度，因为不需要准直。

10. 发明申请

US20100155608A1 OPTIMIZED CASE SPECIFIC SPECT SAMPLING 失效
标题翻译：优化案例特殊采样
公开(公告)号：US20100155608A1
公开(公告)日：2010-06-24
申请号：US12340101
申请日：2008-12-19
申请人： Raymond P. DeVito , Timothy Edwin Doyle
发明人： Raymond P. DeVito , Timothy Edwin Doyle
IPC分类号： G01T1/166 , G01T1/164
CPC分类号： G01T1/00
摘要： A method for improving single photon emission computed tomography by controlling acquisition parameters specific to the imaging goals and specific to the individual case under study. Data acquisition is modulated by scanning to adapt to the particular signal to noise characteristics of each object. A preliminary acquisition quickly scans the object of interest. The preliminary data is analyzed to optimize the secondary scan. The secondary scan is then acquired with optimized sampling of the object based on its own particular image characteristics. The system is able to learn, incorporating site specific data into a triaging set.
摘要翻译：通过控制成像目标特有的获取参数并针对正在研究的个别案例，改进单光子发射计算机断层扫描的方法。通过扫描调制数据采集，以适应每个物体的特定信噪比特性。初步采购可以快速扫描感兴趣的对象。分析初步数据以优化二次扫描。然后基于其自己的特定图像特征对对象的优化采样来获取二次扫描。系统能够学习，将站点特定的数据合并到一个分类组中。

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