专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US6166196A Amplification and detection of Campylobacter jejuni and Campylobacter coli 失效
公开(公告)号：US6166196A
公开(公告)日：2000-12-26
申请号：US503804
申请日：2000-02-14
申请人： Ray A. McMillian , Thomas L. Fort , Qimin You
发明人： Ray A. McMillian , Thomas L. Fort , Qimin You
IPC分类号： C12N15/09 , C12M1/00 , C12Q1/68 , G01N37/00 , C07H21/04 , C12P19/34
CPC分类号： C12Q1/689 , Y02A50/451
摘要： Amplification primers and methods for specific amplification and detection of a Campylobacter jejuni and C. coli target are disclosed. The primer-target binding sequences are useful for amplification and detection of C jejuni and C. coli target in a variety of amplification and detection reactions.

2. 发明授权

US6043041A Amplification and detection of Shiga-like toxin II producing organisms 失效
标题翻译：志贺样毒素Ⅱ生物体的扩增和检测
公开(公告)号：US6043041A
公开(公告)日：2000-03-28
申请号：US289751
申请日：1999-04-12
申请人： Thomas L. Fort , Ray A. McMillian , Qimin You
发明人： Thomas L. Fort , Ray A. McMillian , Qimin You
IPC分类号： G01N33/53 , C12N15/09 , C12Q1/04 , C12Q1/68 , C12R1/19 , G01N33/569 , G01N37/00
CPC分类号： C12Q1/689
摘要： Amplification primers and methods for specific amplification and detection of a Shiga-like toxin II (SLT-II) target are disclosed. The primer-target binding sequences are useful for amplification and detection of SLT-II target in a variety of amplification and detection reactions.
摘要翻译：公开了用于特异性扩增和检测志贺样毒素II（SLT-II）靶的扩增引物和方法。引物 - 靶结合序列可用于在各种扩增和检测反应中扩增和检测SLT-II靶。

3. 发明授权

US6162605A Amplification and detection of shiga-like toxin I producing organisms 失效
标题翻译：扩增和检测志贺样毒素I产生菌
公开(公告)号：US6162605A
公开(公告)日：2000-12-19
申请号：US289803
申请日：1999-04-12
申请人： Thomas L. Fort , Tobin J. Hellyer , Ray A. McMillian , Qimin You
发明人： Thomas L. Fort , Tobin J. Hellyer , Ray A. McMillian , Qimin You
IPC分类号： G01N33/53 , C12M1/00 , C12N15/09 , C12Q1/04 , C12Q1/68 , G01N1/10 , G01N33/566 , G01N33/569 , C07H21/04 , C12P19/34
CPC分类号： C12Q1/689
摘要： Amplification primers and methods for specific amplification and detection of a Shiga-like toxin I (SLT-I) target are disclosed. The primer-target binding sequences are useful for amplification and detection of SLT-I target in a variety of amplification and detection reactions.
摘要翻译：公开了用于特异性扩增和检测志贺样毒素I（SLT-1）靶的扩增引物和方法。引物 - 靶结合序列可用于扩增和检测各种扩增和检测反应中的SLT-1靶。

4. 发明授权

US6066461A Amplification and detection of Campylobacter jejuni and Campylobacter coli 失效
标题翻译：扩增和检测空肠弯曲杆菌和弯曲杆菌
公开(公告)号：US6066461A
公开(公告)日：2000-05-23
申请号：US289747
申请日：1999-04-12
申请人： Ray A. McMillian , Thomas L. Fort , Qimin You
发明人： Ray A. McMillian , Thomas L. Fort , Qimin You
IPC分类号： C12N15/09 , C12M1/00 , C12Q1/68 , G01N37/00 , C12P19/34 , C07H19/00 , C07H21/02 , A61K49/00
CPC分类号： C12Q1/689
摘要： Amplification primers and methods for specific amplification and detection of a Campylobacter jejuni and C. coli target are disclosed. The primer-target binding sequences are useful for amplification and detection of C jejuni and C. coli target in a variety of amplification and detection reactions.
摘要翻译：公开了扩增引物和用于特异性扩增和检测空肠弯曲杆菌和大肠杆菌目标的方法。引物 - 靶结合序列可用于扩增和检测多种扩增和检测反应中的空肠弯曲杆菌和大肠杆菌靶标。

5. 发明申请

US20090149337A1 Use of an Extraction Control in a Method of Extracting Nucleic Acids 有权
标题翻译：在提取核酸的方法中使用提取控制
公开(公告)号：US20090149337A1
公开(公告)日：2009-06-11
申请号：US12062602
申请日：2008-04-04
申请人： Tobin Hellyer , Thomas Fort , Ray A. McMillian , Matthew P. Collis , Thomas L. Fort
发明人： Tobin Hellyer , Thomas Fort , Ray A. McMillian , Matthew P. Collis , Thomas L. Fort
IPC分类号： C40B30/04 , C40B40/08
CPC分类号： C12Q1/6806 , C12Q1/689 , C12Q2545/114 , C12Q2531/113 , C12Q2545/101
摘要： The present invention relates to a method of ensuring the effectiveness of the extraction workup from a biological sample of nucleic acid. The inventive method is able to distinguish between possible defects in the extraction of nucleic acid from a sample and possible defects in a subsequent amplification step. The present invention also relates to a packaged array for extracting nucleic acid from a biological sample.
摘要翻译：本发明涉及确保来自核酸生物样品的提取处理的有效性的方法。本发明的方法能够区分来自样品的核酸提取的可能缺陷以及随后扩增步骤中的可能缺陷。本发明还涉及用于从生物样品中提取核酸的包装阵列。

6. 发明授权

US08859199B2 Use of an extraction control in a method of extracting nucleic acids 有权
标题翻译：在提取核酸的方法中使用提取控制
公开(公告)号：US08859199B2
公开(公告)日：2014-10-14
申请号：US12062602
申请日：2008-04-04
申请人： Tobin Hellyer , Thomas Fort , Ray A. McMillian
发明人： Tobin Hellyer , Thomas Fort , Ray A. McMillian
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/00 , C12N15/00
CPC分类号： C12Q1/6806 , C12Q1/689 , C12Q2545/114 , C12Q2531/113 , C12Q2545/101
摘要： The present invention relates to a method of ensuring the effectiveness of the extraction workup from a biological sample of nucleic acid. The inventive method is able to distinguish between possible defects in the extraction of nucleic acid from a sample and possible defects in a subsequent amplification step. The present invention also relates to a packaged array for extracting nucleic acid from a biological sample.
摘要翻译：本发明涉及确保来自核酸生物样品的提取处理的有效性的方法。本发明的方法能够区分来自样品的核酸提取的可能缺陷以及随后扩增步骤中的可能缺陷。本发明还涉及用于从生物样品中提取核酸的包装阵列。

7. 发明授权

US08658397B2 Assay for detecting closely-related serotypes of human papillomavirus (HPV) 有权
标题翻译：用于检测人乳头状瘤病毒（HPV）密切相关血清型的测定
公开(公告)号：US08658397B2
公开(公告)日：2014-02-25
申请号：US13028589
申请日：2011-02-16
申请人： Chi Chen , Michael Porter , Gregory A. Richart , Ray A. McMillian , Dolores C. Peck
发明人： Chi Chen , Hugh J. Peck , Michael Porter , Gregory A. Richart , Ray A. McMillian
IPC分类号： C12P19/34
CPC分类号： C12Q1/708
摘要： A real time Taq-Man PCR assay for detecting multiple serotypes of human papillomavirus (HPV) wherein the number of serotypes detected exceeds the number of colorimetric channels for detection. A biological sample is combined with three oligonucleotide primer/probe sets such that the probes and primers anneal to a target sequence. Each primer/probe set is at least preferential for a specific serotype of an organism. The first and second primer/probe sets are degenerate with respect to each other. The third primer/probe set is not degenerate with respect to the first and second primer/probe sets and discriminates for a third serotype. The third primer/probe set has a signal moiety that emits signal at a wavelength that is the same or different from the wavelength emitted by the signal moiety of the degenerate primer/probe set probes. The target sequences, if present, are amplified and detected.
摘要翻译：用于检测人乳头状瘤病毒（HPV）的多种血清型的实时Taq-Man PCR测定法，其中检测的血清型数量超过用于检测的比色通道的数量。将生物样品与三种寡核苷酸引物/探针组合，使得探针和引物与靶序列退火。每个引物/探针组对于生物的特定血清型至少是优选的。第一和第二引物/探针组相对于彼此退化。第三引物/探针组相对于第一和第二引物/探针组不退化，并鉴别第三血清型。第三引物/探针组具有在与简并引物/探针组探针的信号部分发射的波长相同或不同的波长处发射信号的信号部分。靶序列（如果存在）被扩增和检测。

8. 发明授权

US07371531B2 Use of an extraction control in a method of extracting nucleic acids 有权
标题翻译：在提取核酸的方法中使用提取控制
公开(公告)号：US07371531B2
公开(公告)日：2008-05-13
申请号：US11114952
申请日：2005-04-25
申请人： Tobin Hellyer , Thomas Fort , Ray A. McMillian
发明人： Tobin Hellyer , Thomas Fort , Ray A. McMillian
IPC分类号： C12Q1/68 , C07H21/00
CPC分类号： C12Q1/6806 , C12Q1/689 , C12Q2545/114 , C12Q2531/113 , C12Q2545/101
摘要： The present invention relates to a method of ensuring the effectiveness of the extraction workup from a biological sample of nucleic acid. The inventive method is able to distinguish between possible defects in the extraction of nucleic acid from a sample and possible defects in a subsequent amplification step. The present invention also relates to a packaged array for extracting nucleic acid from a biological sample.
摘要翻译：本发明涉及确保来自核酸生物样品的提取处理的有效性的方法。本发明的方法能够区分来自样品的核酸提取的可能缺陷以及随后扩增步骤中的可能缺陷。本发明还涉及用于从生物样品中提取核酸的包装阵列。

9. 发明授权

US5447848A Detection of campylobacter with nucleic acid probes 失效
标题翻译：用核酸探针检测弯曲杆菌
公开(公告)号：US5447848A
公开(公告)日：1995-09-05
申请号：US216679
申请日：1988-07-07
申请人： Susan M. Barns , Ray A. McMillian , David J. Lane , Mark L. Collins , James E. Awell , Ayoub Rashtchian
发明人： Susan M. Barns , Ray A. McMillian , David J. Lane , Mark L. Collins , James E. Awell , Ayoub Rashtchian
IPC分类号： C12N15/09 , C07H21/04 , C12N1/20 , C12N15/00 , C12Q1/04 , C12Q1/68 , C12R1/01 , G01N33/50 , C07H21/00 , C12Q1/02
CPC分类号： C12Q1/6813 , C12Q1/689
摘要： Nucleic acid probes capable of specifically hybridizing to rRNA of Campylobacter jejuni, C. coli and C. laridis and not to rRNA or rRNA genes of Pseudomonas aeuroginosa, E. coli or Salmonella typhimunium are described along with methods utilizing such probes for the detection of Campylobacter in clinical, food and other samples.
摘要翻译：与能够与空肠弯曲杆菌，大肠杆菌和C.laridis的rRNA特异性杂交的核酸探针以及不属于恶臭假单胞菌（Pseudomonas aeuroginosa），大肠杆菌或鼠伤寒沙门氏菌的rRNA或rRNA基因的核酸探针与使用这种探针用于检测弯曲杆菌在临床，食品等样品中。

10. 发明授权

US09777336B2 Assay for Chlamydia trachomatis by amplification and detection of Chlamydia trachomatis cytotoxin gene 有权
公开(公告)号：US09777336B2
公开(公告)日：2017-10-03
申请号：US12583832
申请日：2009-08-26
申请人： Courtney E. Maus , Ray A. McMillian
发明人： Courtney E. Maus , Ray A. McMillian
IPC分类号： C12Q1/68
CPC分类号： C12Q1/689
摘要： A region of the Chlamydia trachomatis cytotoxin gene has been identified which is useful for performing amplification assays to determine specifically whether C. trachomatis is present in the sample being tested. Oligonucleotides useful for performing thermal Strand Displacement Assay (tSDA) reactions on this gene are disclosed. The disclosed oligonucleotides can be used in an assay which is specific for multiple strains of C. trachomatis and which does not show cross reactivity with the genomes of other microorganisms or with human DNA.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式