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1. 发明申请

US20070016240A1 Method of reducing rigidity of angioplasty balloon sections 有权
标题翻译：降低血管成形术气囊截面刚度的方法
公开(公告)号：US20070016240A1
公开(公告)日：2007-01-18
申请号：US11455382
申请日：2006-06-19
申请人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Yribarren , Randolf Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
发明人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Yribarren , Randolf Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61M25/1034 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1086 , A61M2025/1093 , B23K2103/42 , B23K2103/50 , B29C59/165 , B29C2791/009 , B29L2031/7542 , Y10T156/1062
摘要： A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.
摘要翻译：根据在球囊和/或导管部分中形成空腔和凹陷的方法制造扩张球囊。一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。气囊的套筒部分中的腔被限定，并且如果需要，限定锥形部分中的凹陷。材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更灵活的粘结区域。此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。袖子附近的刚性减少，导致导管在弯曲通道中的更好的机动性。

2. 发明申请

US20060287703A1 Bifurcation stent delivery catheter assembly and method 审中-公开
标题翻译：分叉支架输送导管组装及方法
公开(公告)号：US20060287703A1
公开(公告)日：2006-12-21
申请号：US11509346
申请日：2006-08-23
申请人： Randolf Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker , Travis Yribarren
发明人： Randolf Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker , Travis Yribarren
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2/856 , A61F2/954 , A61M2025/09125 , A61M2025/1015
摘要： A stent delivery system is disclosed for delivering and deploying a radially expandable stent at a strategic orientation and location in a body vessel. The delivery system includes an elongated flexible tubular shaft sized suitably for insertion into the body vessel. A stent deployment assembly includes a distal transition portion supporting a dilator device adapted for radial expansion about a longitudinal axis of the deployment assembly from a non-expanded condition to a radially expanded condition. The dilator device is configured to support the stent thereon in the non-expanded condition and in predetermined orientation relative the deployment assembly. A rotational clutch assembly rotatably mounts the transition portion to a distal portion of the tubular shaft such that the deployment assembly is substantially torsionally isolated from the tubular shaft, about a longitudinal axis of the clutch assembly. This enables the stent deployment assembly to rotate substantially independently of the tubular shaft for strategic orientation of the dilator device during advancement through the body vessel.
摘要翻译：公开了用于在体内容器中的战略取向和位置处递送和展开径向可扩张的支架的支架输送系统。递送系统包括适于插入身体容器中的细长柔性管状轴。支架展开组件包括支撑扩张器装置的远侧过渡部分，所述扩张器装置适于围绕展开组件的纵向轴线从非扩张状态到径向膨胀状态的径向膨胀。扩张器装置构造成在非扩张状态下以相对于展开组件的预定取向支撑其上的支架。旋转离合器组件将过渡部分可旋转地安装到管状轴的远侧部分，使得展开组件围绕离合器组件的纵向轴线与管状轴基本上扭转隔离。这使得支架展开组件能够基本上独立于管状轴线旋转，以便在穿过身体血管的进展期间扩张器装置的战略取向。

3. 发明申请

US20070288081A1 STENT DELIVERY SYSTEM HAVING A STENT STOPPER 审中-公开
标题翻译：具有STENT STOPPER的STENT交付系统
公开(公告)号：US20070288081A1
公开(公告)日：2007-12-13
申请号：US11747145
申请日：2007-05-10
申请人： Randolf Oepen , Arik Zucker , Travis Yribarren , Thomas Rieth , Lorcan Coffey
发明人： Randolf Oepen , Arik Zucker , Travis Yribarren , Thomas Rieth , Lorcan Coffey
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2002/821 , A61F2002/9586
摘要： Disclosed are stent delivery apparatus and methods for moving a balloon catheter carrying a stent through a body vessel without the stent slipping from the balloon are provided. In general, the stent delivery system includes a stent stopper that impedes the stent from slipping from the balloon. The stent stopper is sized to serve as a barrier to the stent as it is carried on the balloon. In a specific embodiment, the stent stopper is formed from a material that encircles the proximal end of the balloon and abuts the proximal end of the stent. The stent stopper material expands with expansion of the balloon and collapses with deflation of the balloon. In some embodiments, the stent stopper material has a thickness that is about equal to or greater than the thickness of the stent so as to form a barrier against the stent and impede the stent from slipping off the proximal end of the balloon.
摘要翻译：公开了用于移动携带支架的球囊导管通过身体容器而没有支架从气囊滑落的支架输送装置和方法。通常，支架输送系统包括阻止支架从气囊滑落的支架塞子。支架止动器的尺寸被设计成当支架承载在气囊上时用作支架的屏障。在具体实施例中，支架止动器由围绕球囊的近端并邻接支架的近端的材料形成。支架塞材料随气囊膨胀而膨胀，并伴随气囊的放气而塌陷。在一些实施例中，支架止动器材料具有大约等于或大于支架厚度的厚度，以便形成抵靠支架的阻挡层并阻止支架从气囊的近端滑落。

4. 发明申请

US20070021685A1 Guidewire apparatus with an expandable portion and methods of use 审中-公开
标题翻译：具有可扩展部分的导丝装置和使用方法
公开(公告)号：US20070021685A1
公开(公告)日：2007-01-25
申请号：US11429424
申请日：2006-05-04
申请人： Randolf Oepen , Travis Yribarren , Thomas Rieth , Lorcan Coffey , Arik Zucker
发明人： Randolf Oepen , Travis Yribarren , Thomas Rieth , Lorcan Coffey , Arik Zucker
IPC分类号： A61M25/00
CPC分类号： A61M25/09 , A61M2025/09125 , A61M2025/09175 , A61M2025/09183
摘要： A guidewire apparatus for a medical device that includes an expandable guidewire section that can be locked in an expanded state. In one use, the expandable section can be temporarily locked to a working element of a medical device to facilitate the transmission of torque from the guidewire to the medical device. Hence, this configuration may be utilized to aid in orientation of the working element with a vessel side branch by providing the user with the ability to apply a rotational force to the distal end of the stent delivery system. Another use includes docking the expandable section near an opening into a guidewire lumen at the catheter tip. This configuration is particularly useful in forming a smooth transition between the guidewire and the catheter tip to reduce the phenomenon of fish-mouthing.
摘要翻译：一种用于医疗装置的导丝装置，其包括能够被锁定在展开状态的可扩张导丝部分。在一种用途中，可扩张部分可以临时锁定到医疗装置的工作元件，以便于将扭矩从导丝传递到医疗装置。因此，这种构造可以用于通过向使用者提供向支架输送系统的远端施加旋转力的能力来帮助工作元件与血管侧分支的取向。另一种用途包括将开口附近的可扩张部分对接在导管尖端处的导丝管腔中。这种构造在形成导丝和导管尖端之间的平滑过渡以减少鱼嘴的现象特别有用。

5. 发明申请

US20060282154A1 Bifurcation stent delivery catheter assembly and method 审中-公开
公开(公告)号：US20060282154A1
公开(公告)日：2006-12-14
申请号：US11441388
申请日：2006-05-24
申请人： Randolf Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker , Travis Yribarren
发明人： Randolf Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker , Travis Yribarren
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2/856 , A61F2/954 , A61M2025/09125 , A61M2025/1015
摘要： A stent delivery system is disclosed for delivering and deploying a radially expandable stent at a strategic orientation and location in a body vessel. The delivery system includes an elongated flexible tubular shaft sized suitably for insertion into the body vessel. A stent deployment assembly includes a distal transition portion supporting a dilator device adapted for radial expansion about a longitudinal axis of the deployment assembly from a non-expanded condition to a radially expanded condition. The dilator device is configured to support the stent thereon in the non-expanded condition and in predetermined orientation relative the deployment assembly. A rotational clutch assembly rotatably mounts the transition portion to a distal portion of the tubular shaft such that the deployment assembly is substantially torsionally isolated from the tubular shaft, about a longitudinal axis of the clutch assembly. This enables the stent deployment assembly to rotate substantially independently of the tubular shaft for strategic orientation of the dilator device during advancement through the body vessel.

6. 发明申请

US20070016241A1 Balloon catheter 有权
标题翻译：气球导管
公开(公告)号：US20070016241A1
公开(公告)日：2007-01-18
申请号：US11474111
申请日：2006-06-23
申请人： Randolf von Oepen , Lorcan Coffey , Thomas Rieth , Travis Yribarren , Arik Zucker
发明人： Randolf von Oepen , Lorcan Coffey , Thomas Rieth , Travis Yribarren , Arik Zucker
IPC分类号： A61M29/00
CPC分类号： A61M25/10 , A61F2/958 , A61M25/1002 , A61M25/1011 , A61M25/1027 , A61M25/1029 , A61M25/104 , A61M2025/018 , A61M2025/0183 , A61M2025/1045 , A61M2025/1056 , A61M2025/107 , A61M2029/025
摘要： A catheter arrangement is described that is arranged to permit a guide wire or other structure to be fed laterally from the region of an expandable working element. The catheter includes an elongate flexible tubular member and an inflatable structure carried by a distal portion of the flexible tubular member. The flexible tubular member has a guide wire lumen and at least one fluid supply lumen that is in fluid communication with the inflatable structure. The inflatable structure includes at least one, and preferably two, inflatable members (which may take the form of balloons). In the case of two inflatable members, the first and second inflatable members are radially spaced about the guide wire lumen such that at least one gap is formed between the inflatable members. With this arrangement, the distal end of a guide wire may be advanced through the guide lumen and out of a side opening such that the guide wire passes laterally between the first and second inflatable members. With such an arrangement, a guide wire passing out of the side opening in the region between the inflatable members can readily be directed into a second branch of a vessel bifurcation while the device is positioned in a first branch.
摘要翻译：描述了布置成允许导丝或其他结构从可扩张工作元件的区域横向地供给的导管装置。导管包括细长的柔性管状构件和由柔性管状构件的远侧部分承载的可膨胀结构。柔性管状构件具有导丝腔和与可充气结构流体连通的至少一个流体供应腔。可膨胀结构包括至少一个，优选两个可膨胀构件（其可以采取气球的形式）。在两个可膨胀构件的情况下，第一和第二可膨胀构件围绕导丝管腔径向隔开，使得在可膨胀构件之间形成至少一个间隙。通过这种布置，导丝的远端可以通过引导腔前进并且从侧开口排出，使得导丝横向地在第一和第二可膨胀构件之间通过。通过这样的布置，在可膨胀构件之间的区域中的侧开口中的引导线可以容易地被引导到容器分叉的第二分支中，同时装置位于第一分支中。

7. 发明授权

US08292913B2 Method of reducing rigidity of angioplasty balloon sections 有权
标题翻译：降低血管成形术气囊截面刚度的方法
公开(公告)号：US08292913B2
公开(公告)日：2012-10-23
申请号：US13152081
申请日：2011-06-02
申请人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
发明人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61M25/1034 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1086 , A61M2025/1093 , B23K2103/42 , B23K2103/50 , B29C59/165 , B29C2791/009 , B29L2031/7542 , Y10T156/1062
摘要： A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.
摘要翻译：根据在球囊和/或导管部分中形成空腔和凹陷的方法制造扩张球囊。一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。气囊的套筒部分中的腔被限定，并且如果需要，限定锥形部分中的凹陷。材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更灵活的粘结区域。此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。袖子附近的刚性减少，导致导管在曲折通道中的更好的机动性。

8. 发明授权

US08986339B2 Method of reducing rigidity of angioplasty balloon sections 有权
标题翻译：降低血管成形术气囊截面刚度的方法
公开(公告)号：US08986339B2
公开(公告)日：2015-03-24
申请号：US13615096
申请日：2012-09-13
申请人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
发明人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
IPC分类号： A61M29/00 , A61M25/10 , B23K26/40 , B29C59/16 , B29L31/00
CPC分类号： A61M25/104 , A61M25/1034 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1086 , A61M2025/1093 , B23K2103/42 , B23K2103/50 , B29C59/165 , B29C2791/009 , B29L2031/7542 , Y10T156/1062
摘要： A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.
摘要翻译：根据在球囊和/或导管部分中形成空腔和凹陷的方法制造扩张球囊。一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。气囊的套筒部分中的腔被限定，并且如果需要，限定锥形部分中的凹陷。材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更灵活的粘结区域。此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。袖子附近的刚性减少，导致导管在曲折通道中的更好的机动性。

9. 发明申请

US20080097404A1 Catheter having markers to indicate rotational orientation 审中-公开
标题翻译：导管具有指示旋转取向的标记
公开(公告)号：US20080097404A1
公开(公告)日：2008-04-24
申请号：US11505697
申请日：2006-08-16
申请人： Travis R. Yribarren , Randolf von Oepen , Lorcan Coffey , Thomas Rieth , Arik Zucker
发明人： Travis R. Yribarren , Randolf von Oepen , Lorcan Coffey , Thomas Rieth , Arik Zucker
IPC分类号： A61M25/098 , A61M29/00 , A61F2/06 , A61F2/00
CPC分类号： A61M25/0108 , A61F2/856 , A61F2/954 , A61F2/958 , A61F2250/0098 , A61M2025/0008 , A61M2025/1079
摘要： Various improved catheter marking arrangements are described. In a first aspect of the invention, a first longitudinally extending radiopaque marker is positioned on the catheter. A second longitudinally extending radiopaque marker is positioned opposite the first marker at a rotational orientation that is approximately 180 degrees offset from the first marker. The second marker has a length that is sufficiently different from the first marker such that a surgeon utilizing the catheter in a surgical procedure would be able to readily differentiate the first and second markers in a fluoroscopic image based on their respective lengths in order to determine the rotational orientation of the catheter.In some embodiments, the catheter includes a lumen that has a side port that opens to a side of the catheter. The first marker is composed of a pair of axially aligned marker segments located on opposite ends of the side port. The length of the first longitudinal extending marker defined as an end-to-end length of the pair of axially aligned marker segments is longer than the length of the second marker. The markers may be formed from any suitable materials that can be clearly detected by an imaging system.
摘要翻译：描述了各种改进的导管标记装置。在本发明的第一方面，第一纵向延伸的不透射线的标记位于导管上。第二纵向延伸的不透射线标记物以与第一标记物大约180度偏离的旋转方向定位成与第一标记相对。第二标记具有与第一标记足够不同的长度，使得在外科手术中利用导管的外科医生能够根据它们各自的长度容易地区分荧光镜图像中的第一和第二标记，以便确定导管的旋转取向。在一些实施例中，导管包括具有向导管侧面开口的侧端口的内腔。第一标记由位于侧端口的相对端上的一对轴向对齐的标记段组成。被定义为一对轴向对准的标记段的端到端长度的第一纵向延伸标记的长度比第二标记的长度长。标记可以由能够被成像系统清楚地检测到的任何合适的材料形成。

10. 发明授权

US07967836B2 Dilatation balloon having reduced rigidity 有权
标题翻译：具有降低刚度的膨胀气球
公开(公告)号：US07967836B2
公开(公告)日：2011-06-28
申请号：US11455382
申请日：2006-06-19
申请人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
发明人： Boris Warnack , Judith Hartwig , Silke Pschibl , Travis Richard Yribarren , Randolf Von Oepen , Thomas Rieth , Lorcan Coffey , Arik Zucker
IPC分类号： A61M29/00
CPC分类号： A61M25/104 , A61M25/1034 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1086 , A61M2025/1093 , B23K2103/42 , B23K2103/50 , B29C59/165 , B29C2791/009 , B29L2031/7542 , Y10T156/1062
摘要： A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.
摘要翻译：根据在球囊和/或导管部分中形成空腔和凹陷的方法制造扩张球囊。一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。气囊的套筒部分中的腔被限定，并且如果需要，限定锥形部分中的凹陷。材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更灵活的粘结区域。此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。袖子附近的刚性减少，导致导管在弯曲通道中的更好的机动性。

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