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1. 发明申请

US20110270237A1 SYSTEMS AND METHODS OF PERFORMING MEDICAL PROCEDURES 有权
标题翻译：执行医疗程序的系统和方法
公开(公告)号：US20110270237A1
公开(公告)日：2011-11-03
申请号：US12769350
申请日：2010-04-28
申请人： Randell L. Werneth , Marshall Sherman , Mark T. Stewart , J. Christopher Flaherty
发明人： Randell L. Werneth , Marshall Sherman , Mark T. Stewart , J. Christopher Flaherty
IPC分类号： A61B18/02 , A61B5/053 , A61B5/04
CPC分类号： A61B18/1492 , A61B5/01 , A61B5/0402 , A61B5/053 , A61B5/0538 , A61B5/06 , A61B5/063 , A61B5/08 , A61B5/103 , A61B5/6885 , A61B5/7207 , A61B5/743 , A61B18/02 , A61B18/0206 , A61B18/24 , A61B2018/00791 , A61B2018/00875 , A61B2018/0262 , A61B2034/2046 , A61B2090/065 , G06F19/00
摘要： A medical method is provided, including a medical device having a distal assembly including at least one electrode and at least one treatment element, the medical device generating information regarding at least one of a physiological measurement and an operational parameter of the medical device; a plurality of surface electrodes affixable to a skin of the patient, wherein the surface electrodes are in electrical communication with the distal assembly to obtain position information of the medical device; and a processor pairing the position information and the at least one of a physiological measurement and an operational parameter of the medical device.
摘要翻译：提供了一种医疗方法，包括具有远端组件的医疗装置，所述远端组件包括至少一个电极和至少一个治疗元件，所述医疗装置产生关于所述医疗装置的生理测量和操作参数中的至少一个的信息; 多个表面电极可固定在患者皮肤上，其中表面电极与远端组件电连通以获得医疗装置的位置信息; 以及将所述位置信息和所述医疗装置的生理测量和操作参数中的至少一个配对的处理器。

2. 发明授权

US08845631B2 Systems and methods of performing medical procedures 有权
标题翻译：执行医疗程序的系统和方法
公开(公告)号：US08845631B2
公开(公告)日：2014-09-30
申请号：US12769350
申请日：2010-04-28
申请人： Randell L. Werneth , Marshall Sherman , Mark T. Stewart , J. Christopher Flaherty
发明人： Randell L. Werneth , Marshall Sherman , Mark T. Stewart , J. Christopher Flaherty
IPC分类号： A61B18/12 , A61B5/06 , A61B5/053 , A61B18/00 , A61B5/00 , A61B19/00 , A61B5/01 , A61B5/08 , A61B18/24 , A61B18/02 , A61B18/14 , A61B5/103 , A61B5/0402
CPC分类号： A61B18/1492 , A61B5/01 , A61B5/0402 , A61B5/053 , A61B5/0538 , A61B5/06 , A61B5/063 , A61B5/08 , A61B5/103 , A61B5/6885 , A61B5/7207 , A61B5/743 , A61B18/02 , A61B18/0206 , A61B18/24 , A61B2018/00791 , A61B2018/00875 , A61B2018/0262 , A61B2034/2046 , A61B2090/065 , G06F19/00
摘要： A medical method is provided, including a medical device having a distal assembly including at least one electrode and at least one treatment element, the medical device generating information regarding at least one of a physiological measurement and an operational parameter of the medical device; a plurality of surface electrodes affixable to a skin of the patient, wherein the surface electrodes are in electrical communication with the distal assembly to obtain position information of the medical device; and a processor pairing the position information and the at least one of a physiological measurement and an operational parameter of the medical device.
摘要翻译：提供了一种医疗方法，包括具有远端组件的医疗装置，所述远端组件包括至少一个电极和至少一个治疗元件，所述医疗装置产生关于所述医疗装置的生理测量和操作参数中的至少一个的信息; 多个表面电极可固定在患者皮肤上，其中表面电极与远端组件电连通以获得医疗装置的位置信息; 以及将所述位置信息和所述医疗装置的生理测量和操作参数中的至少一个配对的处理器。

3. 发明授权

US07070594B2 System and method for assessing ice ball formation during a cryoablation procedure 有权
标题翻译：在冷冻消融过程中评估冰球形成的系统和方法
公开(公告)号：US07070594B2
公开(公告)日：2006-07-04
申请号：US10775277
申请日：2004-02-10
申请人： Marshall Sherman
发明人： Marshall Sherman
IPC分类号： A61B18/18
CPC分类号： A61B18/02 , A61B2017/00026 , A61B2018/0212 , A61B2018/0262
摘要： Systems and methods for assessing the formation of an ice ball during a cryoablation procedure are disclosed. The system includes a reference electrode that is placed in contact with the patient and a cryocatheter having a cryotip. An electronic circuit is connected to both the cryotip and the reference electrode to measure the impedance therebetween which can be used to assess the formation of an ice ball during a cryoablation procedure. An exemplary measurement signal has a frequency of approximately 20 khz and an RMS voltage of approximately 0.5V. With the cryotip positioned proximate the target tissue, a reference impedance is measured. Next, the conductive tip member is placed in contact with the target tissue and cooled to form an ice ball. During cooling, impedance measurement(s) are taken and compared with the reference impedance to assess the formation of the ice ball.
摘要翻译：公开了在冷冻消融过程中评估冰球形成的系统和方法。该系统包括与患者接触放置的参比电极和具有冷冻滚筒的低温导管。电子电路连接到冷冻血流和参比电极两者以测量它们之间的阻抗，其可以用于评估在冷冻消融过程中冰球的形成。示例性测量信号具有约20khz的频率和约0.5V的RMS电压。当冷冻滚子位于靶组织附近时，测量参考阻抗。接下来，将导电端部构件与靶组织接触并冷却以形成冰球。在冷却期间，采取阻抗测量并与参考阻抗进行比较，以评估冰球的形成。

4. 发明授权

US07901359B2 Ultrasound energy driven intraventricular catheter to treat ischemia 有权
标题翻译：超声能量驱动心室导管治疗缺血
公开(公告)号：US07901359B2
公开(公告)日：2011-03-08
申请号：US11296595
申请日：2005-12-06
申请人： Evgenia Mandrusov , Jeffrey Steward , Marshall Sherman
发明人： Evgenia Mandrusov , Jeffrey Steward , Marshall Sherman
IPC分类号： A61B17/00
CPC分类号： A61N7/022 , A61B2017/00247 , A61B2018/00392
摘要： A method and apparatus for improving blood flow to an ischemic region (e.g., myocardial ischemia) a patient is provided. An ultrasonic transducer is positioned proximate to the ischemic region. Ultrasonic energy is applied at a frequency at or above 1 MHz to create one or more thermal lesions in the ischemic region of the myocardium. The thermal lesions can have a gradient of sizes. The ultrasound transducer can have a curved shape so that ultrasound energy emitted by the transducer converges to a site within the myocardium, to create a thermal lesion without injuring the epicardium or endocardium.
摘要翻译：提供了一种用于改善患者血液流向缺血区域（如心肌缺血）的方法和装置。超声换能器位于缺血区附近。以1MHz以上的频率施加超声波能量，以在心肌的缺血区域中产生一个或多个热损伤。热病变可以有一个大小的梯度。超声换能器可以具有弯曲形状，使得由换能器发射的超声能量收敛到心肌内的位置，以产生热损伤而不损伤心外膜或心内膜。

5. 发明申请

US20060111700A1 Atrial ablation catheter and method of use 有权
公开(公告)号：US20060111700A1
公开(公告)日：2006-05-25
申请号：US10997172
申请日：2004-11-24
申请人： Christopher Kunis , Thomas Castellano , Marshall Sherman , Randell Werneth
发明人： Christopher Kunis , Thomas Castellano , Marshall Sherman , Randell Werneth
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/0016 , A61B2018/00214 , A61B2018/00267 , A61B2018/00351 , A61B2018/1475
摘要： An atrial ablation catheter and methods for its use. The endocardial catheter includes an electrode array particularly adapted to locate and ablate foci of arrhythmia which are required for sustained atrial fibrillation is provided. The array is easily deployed and retracted from the catheter, and presents a distally oriented electrode array that can be pressed against the wall of the atrium.

6. 发明授权

US08834388B2 Method and apparatus to regulate a tissue temperature 有权
标题翻译：调节组织温度的方法和装置
公开(公告)号：US08834388B2
公开(公告)日：2014-09-16
申请号：US12770797
申请日：2010-04-30
申请人： Marshall Sherman
发明人： Marshall Sherman
IPC分类号： A61B5/00
CPC分类号： A61B18/082 , A61B5/01 , A61B18/1492 , A61B2017/00092 , A61B2017/00101 , A61B2018/00357 , A61B2018/00577 , A61B2018/00702 , A61B2018/00714 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821
摘要： A system and method are described for sensing the orientation of a catheter relative to a tissue and regulating the application of power to maintain the tissue at a pre-determined temperature.
摘要翻译：描述了一种系统和方法，用于感测导管相对于组织的取向并调节功率的施加以将组织保持在预定温度。

7. 发明申请

US20070083195A1 Low power tissue ablation system 有权
标题翻译：低功率组织消融系统
公开(公告)号：US20070083195A1
公开(公告)日：2007-04-12
申请号：US11484878
申请日：2006-07-11
申请人： Randell Werneth , Christopher Kunis , J. Flaherty , Marshall Sherman
发明人： Randell Werneth , Christopher Kunis , J. Flaherty , Marshall Sherman
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2017/00084 , A61B2017/00243 , A61B2018/00214 , A61B2018/00351 , A61B2018/00666 , A61B2018/00898 , A61B2018/1467 , A61B2018/1475
摘要： Devices, systems and methods are disclosed for the ablation of tissue. Embodiments include an ablation catheter that has an array of ablation elements attached to a deployable carrier assembly. The carrier assembly can be constrained within the lumen of a catheter, and deployed to take on an expanded condition. The carrier assembly includes multiple electrodes that are configured to ablate tissue at low power. Additional embodiments include a system that includes an interface unit for delivering one or more forms of energy to the ablation catheter.
摘要翻译：公开了用于组织消融的装置，系统和方法。实施例包括消融导管，其具有附接到可展开的载体组件的消融元件阵列。载体组件可以被限制在导管的内腔中，并且被部署以展开扩张状态。载体组件包括被配置成以低功率消融组织的多个电极。另外的实施例包括包括用于将一种或多种形式的能量递送到消融导管的接口单元的系统。

8. 发明申请

US20060106375A1 Ablation system with feedback 有权
公开(公告)号：US20060106375A1
公开(公告)日：2006-05-18
申请号：US11179332
申请日：2005-07-12
申请人： Randell Werneth , Marshall Sherman , J. Flaherty
发明人： Randell Werneth , Marshall Sherman , J. Flaherty
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B8/0833 , A61B2017/00106 , A61B2017/00243 , A61B2018/00351 , A61B2018/00702 , A61B2018/00791
摘要： Devices, systems and methods are disclosed for the ablation of tissue and treatment of cardiac arrhythmia. An ablation system includes an ablation catheter that has an array of ablation elements and a location element, an esophageal probe also including a location element, and an interface unit that provides energy to the ablation catheter. The distance between the location elements, determined by calculating means of the system, can be used by the system to set or modify one or more system parameters.

9. 发明授权

US06740040B1 Ultrasound energy driven intraventricular catheter to treat ischemia 有权
公开(公告)号：US06740040B1
公开(公告)日：2004-05-25
申请号：US09774334
申请日：2001-01-30
申请人： Evgenia Mandrusov , Jeffrey Steward , Marshall Sherman
发明人： Evgenia Mandrusov , Jeffrey Steward , Marshall Sherman
IPC分类号： A61B800
CPC分类号： A61N7/022 , A61B2017/00247 , A61B2018/00392
摘要： A method and apparatus for improving blood flow to an ischemic region (e.g., myocardial ischemia) a patient is provided. An ultrasonic transducer is positioned proximate to the ischemic region. Ultrasonic energy is applied at a frequency at or above 1 MHz to create one or more thermal lesions in the ischemic region of the myocardium. The thermal lesions can have a gradient of sizes. The ultrasound transducer can have a curved shape so that ultrasound energy emitted by the transducer converges to a site within the myocardium, to create a thermal lesion without injuring the epicardium or endocardium.

10. 发明申请

US20110270247A1 Method and Apparatus to Regulate a Tissue Temperature 有权
标题翻译：调节组织温度的方法和装置
公开(公告)号：US20110270247A1
公开(公告)日：2011-11-03
申请号：US12770797
申请日：2010-04-30
申请人： Marshall Sherman
发明人： Marshall Sherman
IPC分类号： A61B18/14 , A61B5/01
CPC分类号： A61B18/082 , A61B5/01 , A61B18/1492 , A61B2017/00092 , A61B2017/00101 , A61B2018/00357 , A61B2018/00577 , A61B2018/00702 , A61B2018/00714 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821
摘要： A system and method are described for sensing the orientation of a catheter relative to a tissue and regulating the application of power to maintain the tissue at a pre-determined temperature.
摘要翻译：描述了一种系统和方法，用于感测导管相对于组织的取向并调节功率的施加以将组织保持在预定温度。

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