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    • 4. 发明授权
    • Apparatus and method for increasing the selectivity of FET-based gas sensors
    • 提高基于FET的气体传感器选择性的装置和方法
    • US07992426B2
    • 2011-08-09
    • US11587171
    • 2005-04-21
    • Maximilian FleischerUwe LampeHans MeixnerRoland PohleRalf SchneiderElfriede Simon
    • Maximilian FleischerUwe LampeHans MeixnerRoland PohleRalf SchneiderElfriede Simon
    • G01N33/00G01N27/414
    • G01N33/0014G01N27/4143
    • A FET gas sensor having a relatively low operating temperature, for example, room temperature, is free from cross sensitivities from interfering gases by a preceding in-line filter. The sensor's service life is substantially stabilizable by using fabric-like activated charcoal filters which can be regenerated by a moderate temperature increase, and by limiting the diffusion of the analyte gas, which is made possible by the relatively small amount of gas detectable on the sensitive layer of the sensor. This substantially increases the service life of the filters. The gas sensor eliminates cross sensitivities to thereby increase the detection reliability thereof. Also, the gas sensor has relative long term stability and is economical to build. The gas sensor can read relatively weak signals generated by gas-sensitive layers, for example, without other stronger gas signals interfering with the weak signals.
    • 具有较低工作温度(例如室温)的FET气体传感器不受前面的在线过滤器的干扰气体的交叉敏感性。 传感器的使用寿命通过使用织物样的活性炭过滤器可以基本上稳定,该过滤器可以通过适度的温度升高再生,并且通过限制分析物气体的扩散,这是通过敏感的可检测的相对少量的气体 传感器层。 这大大增加了过滤器的使用寿命。 气体传感器消除了交叉敏感度,从而提高了其检测可靠性。 此外,气体传感器具有相对的长期稳定性并且构建经济。 气体传感器可以读取由气体敏感层产生的相对较弱的信号,例如,没有其他较强气体信号干扰弱信号。
    • 6. 发明申请
    • Gas Sensor for Determining Ammonia
    • 气体传感器用于测定氨
    • US20080274559A1
    • 2008-11-06
    • US11629550
    • 2005-06-13
    • Maximilian FleischerHans MeixnerRoland PohleKerstin Wiesner
    • Maximilian FleischerHans MeixnerRoland PohleKerstin Wiesner
    • G01N27/00B01J19/00
    • G01N33/0054Y02A50/246Y10T436/175383
    • The invention relates to a gas sensor which is used to detect ammonia by detecting and evaluating conductivity variations on semi-conductive metal oxides, comprising: a substrate, a gas sensitive layer made of a semi-conductive metal oxide, a catalytic filter which is disposed in front of the metal oxide, said filter being used to convert ammonia, contained in the measuring gas, into a NO/NO2 mixture or to only NO2, measuring electrodes which are arranged on the surface of the substrate in order to detect conductivity variations in the semi-conductive metal oxide which is at least sensitive to NO/NO2, a controllable electric heating device which is used to adjust predetermined temperatures at least for the semi-conductive metal oxide, whereby the formed NO/NO2 can be guided to the metal oxide and the content of ammonia in the measuring gas can be determined from the NO/NO2-measurement by means of the semi-conductive metal oxide.
    • 本发明涉及一种用于通过检测和评估半导电金属氧化物的导电率变化来检测氨的气体传感器,包括:基板,由半导体金属氧化物制成的气敏层,设置在催化过滤器 在金属氧化物的前面,所述过滤器用于将包含在测量气体中的氨转化为NO / NO 2混合物或仅将NO2测量电极设置在衬底的表面上,以便检测电导率变化 至少对NO / NO2敏感的半导体金属氧化物,至少用于半导体金属氧化物调节预定温度的可控电加热装置,由此所形成的NO / NO 2可被引导到金属 氧化物,测定气体中的氨的含量可以通过半导体金属氧化物从NO / NO 2测定中求出。
    • 10. 发明申请
    • Biosensor and Method for Operating the Latter
    • 生物传感器和操作后期的方法
    • US20080038749A1
    • 2008-02-14
    • US10588493
    • 2005-01-27
    • Maximilian FleischerCorinna HaindlHans MeixnerElfriede Simon
    • Maximilian FleischerCorinna HaindlHans MeixnerElfriede Simon
    • G01N33/53
    • G01N33/5438
    • A biosensor for detecting an antigen using an antigen/antibody coupling includes: a silicon substrate, at least one interdigital electrode pair structure that is located on the silicon substrate, the electrode pair being interspaced at a maximum distance of 1.0 μm; a counter-electrode on the silicon substrate; a reference electrode; a first layer of protein, covering at least the interdigital electrode structure; a selective second protein layer applied to the first layer and containing a capture antibody selected specifically with respect to the antigen of interest and to which the antigen can be coupled. A sensor signal can be read on the interdigital electrode structure, if the antigen is coupled to the capture antibody by way of a sample to be analysed that comes into contact with the biosensor and a redox reactive molecule is enzymatically released on the sensor surface by an enzyme-marked detection antibody likewise coupled to the antigen.
    • 用于使用抗原/抗体偶联检测抗原的生物传感器包括:硅衬底,位于硅衬底上的至少一个叉指电极对结构,电极对以1.0μm的最大距离进行间隔; 在硅衬底上的对电极; 参考电极; 蛋白质的第一层,至少覆盖指状电极结构; 选择性第二蛋白质层,其施加到第一层并且含有相对于感兴趣的抗原特异性选择的抗体可以偶联的捕获抗体。 如果抗原通过与生物传感器接触的待分析样品与捕获抗体偶联,并且氧化还原反应性分子在传感器表面上被酶促释放,则可以在叉指电极结构上读取传感器信号 同样与抗原偶联的酶标记检测抗体。