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1. 发明授权

US07704214B2 Device and method for the quantitative determination of nitrogen oxides in exhaled air and application thereof 有权
标题翻译：用于定量测定呼出空气中氮氧化物的装置和方法及其应用
公开(公告)号：US07704214B2
公开(公告)日：2010-04-27
申请号：US10476444
申请日：2002-04-30
申请人： Klaus Abraham-Fuchs , Maximilian Fleischer , Hans Meixner , Eva Rumpel , Elfriede Simon
发明人： Klaus Abraham-Fuchs , Maximilian Fleischer , Hans Meixner , Eva Rumpel , Elfriede Simon
IPC分类号： A61B5/08 , G01N31/00
CPC分类号： G01N33/497 , A61B5/082 , A61B5/097 , G01N27/4143 , G01N33/0013 , G01N33/0037 , Y02A50/245
摘要： A volumetric flow of an analyte, including exhaled air, is fed to a gas sensor unit by used of gas flow device, which can include various sensors for the determination of nitrogen oxides. An oxidation catalyst is used when using an NO2 sensor, which converts nitrogen monoxide to nitrogen dioxide and the gas sensor unit measures the content of nitrogen dioxide. The nitrogen monoxide content is calculated from the nitrogen dioxide content. In order to eliminate cross-sensitivity moisture and ethanol are also measured. The device can be applied to the determination of nitrogen monoxide content of exhaled air.
摘要翻译：包括呼出空气的分析物的体积流量通过使用气流装置供给到气体传感器单元，其可以包括用于测定氮氧化物的各种传感器。当使用将一氧化氮转化为二氧化氮的NO 2传感器使用氧化催化剂时，气体传感器单元测量二氧化氮的含量。一氧化氮含量由二氧化氮含量计算。为了消除交叉敏感性，也测量了水分和乙醇。该装置可用于测定呼出空气中的一氧化氮含量。

2. 发明授权

US07992426B2 Apparatus and method for increasing the selectivity of FET-based gas sensors 有权
标题翻译：提高基于FET的气体传感器选择性的装置和方法
公开(公告)号：US07992426B2
公开(公告)日：2011-08-09
申请号：US11587171
申请日：2005-04-21
申请人： Maximilian Fleischer , Uwe Lampe , Hans Meixner , Roland Pohle , Ralf Schneider , Elfriede Simon
发明人： Maximilian Fleischer , Uwe Lampe , Hans Meixner , Roland Pohle , Ralf Schneider , Elfriede Simon
IPC分类号： G01N33/00 , G01N27/414
CPC分类号： G01N33/0014 , G01N27/4143
摘要： A FET gas sensor having a relatively low operating temperature, for example, room temperature, is free from cross sensitivities from interfering gases by a preceding in-line filter. The sensor's service life is substantially stabilizable by using fabric-like activated charcoal filters which can be regenerated by a moderate temperature increase, and by limiting the diffusion of the analyte gas, which is made possible by the relatively small amount of gas detectable on the sensitive layer of the sensor. This substantially increases the service life of the filters. The gas sensor eliminates cross sensitivities to thereby increase the detection reliability thereof. Also, the gas sensor has relative long term stability and is economical to build. The gas sensor can read relatively weak signals generated by gas-sensitive layers, for example, without other stronger gas signals interfering with the weak signals.
摘要翻译：具有较低工作温度（例如室温）的FET气体传感器不受前面的在线过滤器的干扰气体的交叉敏感性。传感器的使用寿命通过使用织物样的活性炭过滤器可以基本上稳定，该过滤器可以通过适度的温度升高再生，并且通过限制分析物气体的扩散，这是通过敏感的可检测的相对少量的气体传感器层。这大大增加了过滤器的使用寿命。气体传感器消除了交叉敏感度，从而提高了其检测可靠性。此外，气体传感器具有相对的长期稳定性并且构建经济。气体传感器可以读取由气体敏感层产生的相对较弱的信号，例如，没有其他较强气体信号干扰弱信号。

3. 发明授权

US07772617B2 Gas sensitive field-effect-transistor 有权
标题翻译：气体敏感场效应晶体管
公开(公告)号：US07772617B2
公开(公告)日：2010-08-10
申请号：US11393371
申请日：2006-03-30
申请人： Maximilian Fleischer , Hans Meixner , Uwe Lampe , Roland Pohle , Ralf Schneider , Elfriede Simon
发明人： Maximilian Fleischer , Hans Meixner , Uwe Lampe , Roland Pohle , Ralf Schneider , Elfriede Simon
IPC分类号： G01N27/414
CPC分类号： G01N27/4143
摘要： A gas sensitive field effect transistor comprises a semiconductor substrate that includes a capacitance well, and source and drain regions of a field effect transistor. A gate of the field effect transistor is separated from the semiconductor substrate by an insulator, and a gas sensitive layer separated from the gate by an air gap. The field effect transistor provides an output signal indicative of the presence of a target gas within the air gap to an amplifier, which provides an amplified output signal that is electrically coupled to the capacitance well.
摘要翻译：气体敏感场效应晶体管包括包括电容阱的半导体衬底以及场效应晶体管的源极和漏极区。场效应晶体管的栅极通过绝缘体与半导体衬底分离，气敏层由气隙与栅极分离。场效应晶体管提供指示空气间隙内存在目标气体到放大器的输出信号，放大器提供与电容阱电耦合的放大输出信号。

4. 发明申请

US20070235773A1 Gas-sensitive field-effect transistor for the detection of hydrogen sulfide 审中-公开
标题翻译：用于检测硫化氢的气敏场效应晶体管
公开(公告)号：US20070235773A1
公开(公告)日：2007-10-11
申请号：US11396276
申请日：2006-03-31
申请人： Ignaz Eisele , Maximilian Fleischer , Gunter Freitag , Thorsten Knittel , Uwe Lampe , Hans Meixner , Roland Pohle , Elfriede Simon
发明人： Ignaz Eisele , Maximilian Fleischer , Gunter Freitag , Thorsten Knittel , Uwe Lampe , Hans Meixner , Roland Pohle , Elfriede Simon
IPC分类号： H01L23/58
CPC分类号： G01N27/4143
摘要： A gas-sensitive field-effect transistor (GasFET) for the detection or measurement of an amount of hydrogen sulfide present in ambient air includes a raised gate electrode and a transistor structure. The raised gate electrode may be formed from or coated with a gas-sensitive material such as tin oxide, or silver, silver oxide or mixtures thereof. An insulator layer may be disposed on top of the transistor structure. An air gap is formed between the gas-sensitive layer of the raised gate electrode and the insulator layer on top of the transistor structure.
摘要翻译：用于检测或测量环境空气中存在的硫化氢的量的气体敏感场效应晶体管（GasFET）包括升高的栅电极和晶体管结构。升高的栅电极可以由气体敏感材料如氧化锡或银，氧化银或其混合物形成或涂覆。绝缘体层可以设置在晶体管结构的顶部。在凸极栅电极的气体敏感层和晶体管结构顶部的绝缘体层之间形成气隙。

5. 发明授权

US06915678B2 Ozone sensor operating according to the work function measurement principle 失效
标题翻译：臭氧传感器根据工作功能测量原理运行
公开(公告)号：US06915678B2
公开(公告)日：2005-07-12
申请号：US10422713
申请日：2003-04-25
申请人： Maximilian Fleischer , Hans Meixner , Bernhard Ostrick , Roland Pohle , Elfriede Simon , Martin Zimmer
发明人： Maximilian Fleischer , Hans Meixner , Bernhard Ostrick , Roland Pohle , Elfriede Simon , Martin Zimmer
IPC分类号： G01N27/414 , G01N33/00 , G01N7/00 , H01L23/58
CPC分类号： G01N33/0039 , G01N27/4143 , Y02A50/247
摘要： An ozone sensor has an ozone-sensitive layer containing an ozone-sensitive material which is encapsulated in a polymer or in a polymer mixture or is coated by at least one polymer or polymer mixture. Advantages result from a longer service life of the ozone-sensitive materials which, because of their high hygroscopic properties, would not be stable without encapsulation or coating. Furthermore, a polymer matrix can be selectively used as a filter or in order to eliminate interfering influences.
摘要翻译：臭氧传感器具有包含臭氧敏感材料的臭氧敏感层，其被包封在聚合物或聚合物混合物中或被至少一种聚合物或聚合物混合物涂覆。优点是由于其具有高吸湿性能的臭氧敏感材料的使用寿命更长，在不进行包封或涂覆的情况下将不稳定。此外，聚合物基质可以选择性地用作过滤器或为了消除干扰影响。

6. 发明授权

US07946153B2 Method for measuring gases and/or minimizing cross sensitivity in FET-based gas sensors 有权
标题翻译：在基于FET的气体传感器中测量气体和/或最小化交叉灵敏度的方法
公开(公告)号：US07946153B2
公开(公告)日：2011-05-24
申请号：US11587173
申请日：2005-04-22
申请人： Maximilian Fleischer , Uwe Lampe , Hans Meixner , Roland Pohle , Elfriede Simon
发明人： Maximilian Fleischer , Uwe Lampe , Hans Meixner , Roland Pohle , Elfriede Simon
IPC分类号： G01N7/00
CPC分类号： G01N27/4143 , G01N33/006
摘要： A gas sensor based on a field effect transistor (“FET”) evaluates both a change in work function of a gas-sensitive layer of the FET and a change in the capacitance of the layer. Thus, two physically independent signals are read from the gas-sensitive layer, each signal representing a sensitivity to a different gas. This reduces the effect of cross-sensitivities; that is, of one gas on the target gas. The underlying physical mechanisms, the first causing a change in the work function in a reaction with gases and the second causing a change in the capacitance of the sensitive layer, are widely different. Because of this, the two parameters demonstrate different gas sensitivities. If the reactions to both gases are known, the effect of the interfering gas on the sensor signal can be compensated for, and with this the concentration of the target gas can be determined.
摘要翻译：基于场效应晶体管（“FET”）的气体传感器评估FET的气敏层的功函数变化和层的电容变化。因此，从气体敏感层读取两个物理独立的信号，每个信号表示对不同气体的敏感性。这降低了交叉敏感性的影响; 也就是目标气体上的一种气体。潜在的物理机制，首先引起与气体反应的功函数的变化，第二个导致敏感层的电容变化的物理机制是不同的。因此，这两个参数表现出不同的气体敏感性。如果对两种气体的反应是已知的，则可以补偿干扰气体对传感器信号的影响，并且可以确定目标气体的浓度。

7. 发明申请

US20090211437A1 Apparatus and Method for increasing the selectivity of fet-based gas sensors 审中-公开
标题翻译：用于增加基于胎面的气体传感器的选择性的装置和方法
公开(公告)号：US20090211437A1
公开(公告)日：2009-08-27
申请号：US11587171
申请日：2005-04-21
申请人： Maximilian Fleischer , Uwe Lampe , Hans Meixner , Roland Pohle , Ralf Schneider , Elfriede Simon
发明人： Maximilian Fleischer , Uwe Lampe , Hans Meixner , Roland Pohle , Ralf Schneider , Elfriede Simon
IPC分类号： G01N27/414
CPC分类号： G01N33/0014 , G01N27/4143
摘要： A FET gas sensor having a relatively low operating temperature, for example, room temperature, is free from cross sensitivities from interfering gases by a preceding in-line filter. The sensor's service life is substantially stabilizable by using fabric-like activated charcoal filters which can be regenerated by a moderate temperature increase, and by limiting the diffusion of the analyte gas, which is made possible by the relatively small amount of gas detectable on the sensitive layer of the sensor. This substantially increases the service life of the filters. The gas sensor eliminates cross sensitivities to thereby increase the detection reliability thereof. Also, the gas sensor has relative long term stability and is economical to build. The gas sensor can read relatively weak signals generated by gas-sensitive layers, for example, without other stronger gas signals interfering with the weak signals.
摘要翻译：具有较低工作温度（例如室温）的FET气体传感器不受前面的在线过滤器的干扰气体的交叉敏感性。传感器的使用寿命通过使用织物样的活性炭过滤器可以基本上稳定，该过滤器可以通过适度的温度升高再生，并且通过限制分析物气体的扩散，这是通过敏感的可检测的相对少量的气体传感器层。这大大增加了过滤器的使用寿命。气体传感器消除了交叉敏感度，从而提高了其检测可靠性。此外，气体传感器具有相对的长期稳定性并且构建经济。气体传感器可以读取由气体敏感层产生的相对较弱的信号，例如，没有其他较强气体信号干扰弱信号。

8. 发明申请

US20080038749A1 Biosensor and Method for Operating the Latter 有权
标题翻译：生物传感器和操作后期的方法
公开(公告)号：US20080038749A1
公开(公告)日：2008-02-14
申请号：US10588493
申请日：2005-01-27
申请人： Maximilian Fleischer , Corinna Haindl , Hans Meixner , Elfriede Simon
发明人： Maximilian Fleischer , Corinna Haindl , Hans Meixner , Elfriede Simon
IPC分类号： G01N33/53
CPC分类号： G01N33/5438
摘要： A biosensor for detecting an antigen using an antigen/antibody coupling includes: a silicon substrate, at least one interdigital electrode pair structure that is located on the silicon substrate, the electrode pair being interspaced at a maximum distance of 1.0 μm; a counter-electrode on the silicon substrate; a reference electrode; a first layer of protein, covering at least the interdigital electrode structure; a selective second protein layer applied to the first layer and containing a capture antibody selected specifically with respect to the antigen of interest and to which the antigen can be coupled. A sensor signal can be read on the interdigital electrode structure, if the antigen is coupled to the capture antibody by way of a sample to be analysed that comes into contact with the biosensor and a redox reactive molecule is enzymatically released on the sensor surface by an enzyme-marked detection antibody likewise coupled to the antigen.
摘要翻译：用于使用抗原/抗体偶联检测抗原的生物传感器包括：硅衬底，位于硅衬底上的至少一个叉指电极对结构，电极对以1.0μm的最大距离进行间隔; 在硅衬底上的对电极; 参考电极; 蛋白质的第一层，至少覆盖指状电极结构; 选择性第二蛋白质层，其施加到第一层并且含有相对于感兴趣的抗原特异性选择的抗体可以偶联的捕获抗体。如果抗原通过与生物传感器接触的待分析样品与捕获抗体偶联，并且氧化还原反应性分子在传感器表面上被酶促释放，则可以在叉指电极结构上读取传感器信号同样与抗原偶联的酶标记检测抗体。

9. 发明申请

US20070220954A1 Fet-Based Gas Sensor 有权
标题翻译：基于FET的气体传感器
公开(公告)号：US20070220954A1
公开(公告)日：2007-09-27
申请号：US11587172
申请日：2005-04-21
申请人： Maximilian Fleischer , Hans Meixner , Elfriede Simon , Uwe Lampe , Roland Pohle
发明人： Maximilian Fleischer , Hans Meixner , Elfriede Simon , Uwe Lampe , Roland Pohle
IPC分类号： B01L5/00 , G01N33/00
CPC分类号： G01N33/0013 , G01N27/4143
摘要： The invention relates to an FET-based gas sensor comprising a gas channel for diffusing a measuring gas to a gas-sensitive layer which is actively connected to a FET for signal readout. According to the invention, an electrochemical element is at least partially inserted into the gas channel for the electrochemical conversion of interfering gases. The arrangement is permeable to the target gas.
摘要翻译：本发明涉及一种基于FET的气体传感器，其包括用于将测量气体扩散到气敏层的气体通道，气敏层主动连接到用于信号读出的FET。根据本发明，电化学元件至少部分地插入气体通道中用于干扰气体的电化学转化。该装置对目标气体是可渗透的。

10. 发明申请

US20060278528A1 Method of effecting a signal readout on a gas-sensitive field-effect transistor 有权
标题翻译：在气敏场效应晶体管上实现信号读出的方法
公开(公告)号：US20060278528A1
公开(公告)日：2006-12-14
申请号：US11393371
申请日：2006-03-30
申请人： Maximilian Fleischer , Hans Meixner , Uwe Lampe , Roland Pohle , Ralf Schneider , Elfriede Simon
发明人： Maximilian Fleischer , Hans Meixner , Uwe Lampe , Roland Pohle , Ralf Schneider , Elfriede Simon
IPC分类号： G01N27/26 , H01L23/58
CPC分类号： G01N27/4143
摘要： Method of effecting a readout of a gas-sensitive field-effect transistor having an air gap between a gate electrode with a gas-sensitive layer and the readout transistor, in which a potential occurring on the gas-sensitive layer in the presence of a target gas is passed through a noncontacting floating gate electrode to the transistor, wherein the potential of a reference electrode, which together with the floating gate electrode generates a capacitance Cw, is tracked to the potential of the floating gate electrode in order to eliminate the capacitance Cw during the measurement.
摘要翻译：在具有气体敏感层的栅电极和读出晶体管之间进行气体敏感场效应晶体管的读出的方法，其中在存在目标的情况下在气敏层上发生电位气体通过非接触式浮栅电极到达晶体管，其中参考电极的电位与浮动栅电极一起产生电容C w i被追踪到浮置栅极的电位电极，以便在测量期间消除电容C 。

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