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    • 2. 发明申请
    • Methods for determination of haplotype dissection
    • 确定单倍型解剖的方法
    • US20100099092A1
    • 2010-04-22
    • US12457697
    • 2009-06-18
    • Qing SongLi MaYan Xiao
    • Qing SongLi MaYan Xiao
    • C12Q1/68
    • C12Q1/6827
    • A method for molecular haplotyping of a subject is disclosed. The method comprises: randomly selecting a set of chromosomes in each of a plurality of lyzed diploid cells of the subject, collecting the selected chromosomes from said plurality of cells into a plurality of sample tubes, wherein each sample tube contains chromosomes selected from one or more cells, genotyping genomic DNA in each sample tube, and determining haplotype of the alleles based on allele nucleotide sequence information and corresponding nucleotide signal intensities from genotyping data. Other methods for molecular haplotyping using single cell lysate or single cell microdissection are also disclosed.
    • 公开了一种受试者的分子单倍型的方法。 该方法包括:在受试者的多个裂解的二倍体细胞的每一个中随机选择一组染色体,将所选择的染色体从所述多个细胞收集到多个样品管中,其中每个样品管含有选自一个或多个 细胞,每个样品管中的基因组DNA的基因分型,以及基于等位基因序列信息和来自基因分型数据的相应核苷酸信号强度确定等位基因的单元型。 还公开了使用单细胞裂解物或单细胞显微切割的分子单倍型的其它方法。
    • 3. 发明授权
    • Methods for determination of haplotype dissection
    • 确定单倍型解剖的方法
    • US08759035B2
    • 2014-06-24
    • US12457697
    • 2009-06-18
    • Qing SongLi MaYan Xiao
    • Qing SongLi MaYan Xiao
    • C12P19/34C12Q1/68
    • C12Q1/6827
    • A method for molecular haplotyping of a subject is disclosed. The method comprises: randomly selecting a set of chromosomes in each of a plurality of lyzed diploid cells of the subject, collecting the selected chromosomes from said plurality of cells into a plurality of sample tubes, wherein each sample tube contains chromosomes selected from one or more cells, genotyping genomic DNA in each sample tube, and determining haplotype of the alleles based on allele nucleotide sequence information and corresponding nucleotide signal intensities from genotyping data. Other methods for molecular haplotyping using single cell lysate or single cell microdissection are also disclosed.
    • 公开了一种受试者的分子单倍型的方法。 该方法包括:在受试者的多个裂解的二倍体细胞的每一个中随机选择一组染色体,将所选择的染色体从所述多个细胞收集到多个样品管中,其中每个样品管含有选自一个或多个 细胞,每个样品管中的基因组DNA的基因分型,以及基于等位基因序列信息和来自基因分型数据的相应核苷酸信号强度确定等位基因的单元型。 还公开了使用单细胞裂解物或单细胞显微切割的分子单倍型的其它方法。
    • 4. 发明申请
    • METHODS FOR DETERMINATION OF HAPLOTYPE DISSECTION
    • 用于确定脂肪分解的方法
    • US20120208183A1
    • 2012-08-16
    • US13267409
    • 2011-10-06
    • Qing SongLi MaYan Xiao
    • Qing SongLi MaYan Xiao
    • C12Q1/68
    • C12Q1/6827
    • A method for molecular haplotyping of a subject is disclosed. The method comprises: randomly selecting a set of chromosomes in each of a plurality of lyzed diploid cells of the subject, collecting the selected chromosomes from said plurality of cells into a plurality of sample tubes, wherein each sample tube contains chromosomes selected from one or more cells, genotyping genomic DNA in each sample tube, and determining haplotype of the alleles based on allele nucleotide sequence information and corresponding nucleotide signal intensities from genotyping data. Other methods for molecular haplotyping using single cell lysate or single cell microdissection are also disclosed.
    • 公开了一种受试者的分子单倍型的方法。 该方法包括:在受试者的多个裂解的二倍体细胞的每一个中随机选择一组染色体,将所选择的染色体从所述多个细胞收集到多个样品管中,其中每个样品管含有选自一个或多个 细胞,每个样品管中的基因组DNA的基因分型,以及基于等位基因序列信息和来自基因分型数据的相应核苷酸信号强度确定等位基因的单元型。 还公开了使用单细胞裂解物或单细胞显微切割的分子单倍型的其它方法。
    • 6. 发明授权
    • Electronic device
    • 电子设备
    • US08876299B2
    • 2014-11-04
    • US13386261
    • 2009-07-21
    • Qing Song
    • Qing Song
    • G03B21/14H05K5/02F16M11/10
    • G03B21/14F16M11/10G03B21/145H05K5/0234
    • An electronic device of the present application includes a case (1), a stem-shaped leg (3), and a leg fixing part (4). The leg fixing part (4) is provided on one face of the case (1) and includes a case thread ridge portion (4a) that is formed on an inside face of a hole, into which the leg (3) is inserted, and that is divided into isolated thread ridge portions. A peripheral face of a stem portion of the leg (3) has a first screw structure portion (3a), which is engaged with the case thread ridge portion (4a), and a second screw structure portion (3b) which is engaged with the case thread ridge portion (4a) before being engaged with the first screw structure portion (3a). The second screw structure portion (3b) has a guide portion (5a) and an idle turn inducing portion (5b). The guide portion (5a) guides the case thread ridge portion (4a) to the second screw structure portion (3b) when the leg (3) is inserted into the hole while being turned in a direction in which the leg (3) enters the case (1). The idle turn inducing portion (5b) causes the second screw structure portion (3b) to turn idly with respect to the case thread ridge portion (4a) when the leg (3) is turned in a direction in which the leg (3) is taken out of the case (1).
    • 本申请的电子设备包括壳体(1),杆状腿部(3)和腿部固定部件(4)。 腿部固定部分(4)设置在壳体(1)的一个面上,并且包括形成在其中插入腿部(3)的孔的内表面上的壳体螺纹脊部分(4a),以及 分为孤立螺纹脊部分。 腿部(3)的杆部的周面具有与壳线螺纹部(4a)接合的第一螺纹结构部(3a)和与第一螺纹结构部(3b)接合的第二螺钉结构部(3b) 在与第一螺杆结构部分(3a)接合之前的壳体螺纹脊部分(4a)。 第二螺杆结构部分(3b)具有引导部分(5a)和怠速转弯诱导部分(5b)。 当腿(3)插入孔中时,引导部(5a)将壳线螺纹部分(4a)引导到第二螺钉结构部分(3b),同时沿腿部(3)进入方向转动 情况1)。 怠速转向诱导部分(5b)使得当腿部(3)沿腿部(3)的方向转动时,第二螺钉结构部分(3b)相对于壳体螺纹脊部分(4a)空转, 取出案件(1)。
    • 7. 发明申请
    • TILT FOOT MECHANISM AND PROJECTION DISPLAY INCLUDING THE MECHANISM
    • 包括机械的倾斜机械和投影显示
    • US20120085885A1
    • 2012-04-12
    • US13378350
    • 2009-07-07
    • Qing Song
    • Qing Song
    • H05K7/00F16M11/24
    • G03B21/145
    • A tilt foot mechanism adjusts a tilt angle of a case by adjusting a length of a protruding portion of a foot protruding from the case, and the tilt foot mechanism includes: a base into which the foot is inserted, wherein the base guides a protruding direction of the inserted foot; and a lever that is assembled with the base and that fixes the foot to the base by being biased to the foot, wherein the lever is rotatable, and the lever is maintained in astute of fixing the foot by a biasing force in a first direction, and the lever releases fixing of the foot by being rotated in a second direction different from the first direction, wherein a first guiding portion and a second guiding portion are provided at the base, wherein the first guiding portion and the second guiding portion define a rotation center of the lever when the first guiding portion and the second guiding portion are assembled with the base, and wherein a first guided portion, a second guided portion, and an engaging portion are provided at the lever, wherein the first guided portion and the second guided portion slide along the first guiding portion and the second guiding portion, and wherein the engaging portion remains in a state of being assembled with the base.
    • 倾斜脚机构通过调整从壳体突出的脚部的突出部的长度来调整壳体的倾斜角度,并且倾斜脚架机构包括:脚部插入其中的基部,其中,基部引导突出方向 插脚; 以及杠杆,其与所述基座组装并且通过偏压到所述脚将所述脚固定到所述基座,其中所述杠杆是可旋转的,并且所述杠杆通过在第一方向上的偏置力而被固定在所述杆上, 并且所述杆通过沿与所述第一方向不同的第二方向旋转来释放所述脚的固定,其中,所述第一引导部和第二引导部设置在所述基座处,其中所述第一引导部和所述第二引导部限定旋转 当所述第一引导部分和所述第二引导部分与所述基座组装时所述杠杆的中心,并且其中在所述杠杆处设置有第一引导部分,第二引导部分和接合部分,其中所述第一引导部分和所述第二引导部分 引导部分沿着第一引导部分和第二引导部分滑动,并且其中接合部分保持在与基部组装的状态。
    • 9. 发明授权
    • Methods and compositions for correlating tissue kallikrein gene promoter polymorphisms with treatment of essential hypertension
    • 将组织激肽释放酶基因启动子多态性与原发性高血压治疗相关联的方法和组合物
    • US06376182B1
    • 2002-04-23
    • US09495140
    • 2000-01-31
    • Lee ChaoJulie ChaoQing Song
    • Lee ChaoJulie ChaoQing Song
    • C12Q168
    • C12Q1/6883C12Q2600/106C12Q2600/156
    • The present invention provides a method of identifying a human subject as having an increased likelihood of regulating blood pressure with dietary sodium intake, comprising determining the presence in the subject of a tissue kallikrein promoter allele genotype correlated with an increased likelihood of regulating blood pressure with dietary sodium intake, whereby the presence of the genotype identifies the subject as having an increased likelihood of regulating blood pressure by dietary sodium intake. Also provided is a method of identifying a tissue kallikrein promoter allele genotype correlated with an increased likelihood of regulating blood pressure with dietary sodium intake, comprising a) determining the tissue kallikrein promoter allele genotype of a subject; and b) correlating the presence of the genotype of step (a) with the ability of the subject to regulate blood pressure by dietary sodium intake, thereby identifying a genotype correlated with an increased likelihood of regulating blood pressure by dietary sodium intake.
    • 本发明提供了一种将人受试者鉴定为具有增加的饮食钠摄入调节血压的可能性的方法,其包括确定受试者中存在与饮食调节血压的增加的可能性相关的组织激肽释放酶启动子等位基因基因型 钠摄入量,从而基因型的存在将受试者识别为具有通过饮食钠摄入调节血压的可能性增加。 还提供了鉴定与膳食钠摄入调节血压的可能性增加相关的组织激肽释放酶启动子等位基因型的方法,其包括a)确定受试者的组织激肽释放酶启动子等位基因型; 和b)将步骤(a)的基因型的存在与受试者通过饮食钠摄入调节血压的能力相关联,从而鉴定与膳食钠摄入调节血压的可能性增加相关的基因型。