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1. 发明申请

US20050267158A1 Polymorphic and amorphous forms of 2,5-dimethyl-2H-pyrazole-3-carboxylic acid {2-fluoro-5-[3-((E)-2 pyridin-2-YL-vinyl)-1H-indazol-6-ylamino]-phenyl}-amide 审中-公开
标题翻译： 2,5-二甲基-2H-吡唑-3-羧酸{2-氟-5- [3 - （（E）-2-吡啶-2-基） - 乙烯基）-1H-吲唑-6-羧酸的多晶型和无定形形式，吡啶-2-基氨基] - 苯基} - 酰胺
公开(公告)号：US20050267158A1
公开(公告)日：2005-12-01
申请号：US11081708
申请日：2005-03-15
申请人： Qiang Ye , Scott Zook , Michael Ouellette , Don Hettinger , Jayaram Srirangam , Robert Kania , Nabil Saeed , Matthew Wightlin , Mark Mitchell
发明人： Qiang Ye , Scott Zook , Michael Ouellette , Don Hettinger , Jayaram Srirangam , Robert Kania , Nabil Saeed , Matthew Wightlin , Mark Mitchell
IPC分类号： A61K31/4439 , C07D401/14 , C07D43/14
CPC分类号： C07D401/14
摘要： The invention provides several polymorphic forms and an amorphous form of 2,5-Dimethyl-2H-pyrazole-3-carboxylic acid {2-fluoro-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylamino]-phenyl}-amide, pharmaceutical compositions containing such polymorphic or amorphous forms, and methods of using such pharmaceutical compositions to treat disease states mediated by protein kinases, such as cancer and other disease states associated with unwanted angiogenesis and/or cellular proliferation.
摘要翻译：本发明提供了几种多晶型和无定形形式的2,5-二甲基-2H-吡唑-3-羧酸{2-氟-5- [3 - （（E）-2-吡啶-2-基 - 乙烯基） -1H-吲唑-6-基氨基] - 苯基} - 酰胺，含有这种多晶型或无定形形式的药物组合物，以及使用这种药物组合物治疗由蛋白激酶介导的疾病状态的方法，例如与不想要的血管生成和/或细胞增殖。

2. 发明申请

US20060094881A1 Methods of preparing indazole compounds 失效
标题翻译：吲唑化合物的制备方法
公开(公告)号：US20060094881A1
公开(公告)日：2006-05-04
申请号：US11264440
申请日：2005-10-31
申请人： Brigitte Ewanicki , Erik Flahive , Annie Kasparian , Mark Mitchell , Michael Perry , Stacy O'Neill-Slawecki , Neal Sach , James Saenz , Bing Shi , Nebojsa Stankovic , Jayaram Srirangam , Qingping Tian , Shu Yu
发明人： Brigitte Ewanicki , Erik Flahive , Annie Kasparian , Mark Mitchell , Michael Perry , Stacy O'Neill-Slawecki , Neal Sach , James Saenz , Bing Shi , Nebojsa Stankovic , Jayaram Srirangam , Qingping Tian , Shu Yu
IPC分类号： C07D403/02 , C07D231/56
CPC分类号： C07D401/06 , C07D231/56
摘要： The present invention relates to methods for preparing indazole compounds of formula I, which are useful as modulators and/or inhibitors of protein kinases. The present invention also relates to intermediate compounds useful in the preparation of compounds of formula I.
摘要翻译：本发明涉及制备式I的吲唑化合物的方法，其可用作蛋白激酶的调节剂和/或抑制剂。本发明还涉及可用于制备式I化合物的中间体化合物。

3. 发明申请

US20120040144A1 Corrugating Adhesive and Use Thereof 审中-公开
标题翻译：波纹粘合剂及其用途
公开(公告)号：US20120040144A1
公开(公告)日：2012-02-16
申请号：US13190825
申请日：2011-07-26
申请人： Shawn DeJong , Mark Mitchell
发明人： Shawn DeJong , Mark Mitchell
IPC分类号： B32B3/28 , C08L1/00
CPC分类号： B32B7/12 , B32B7/05 , B32B29/005 , B32B29/08 , B32B2250/05 , B32B2255/12 , B32B2255/26 , B32B2307/732 , C08L1/00 , C08L31/04 , C08L33/08 , C09D101/02 , C09D101/28 , C09D101/284 , C09D101/286 , C09J131/04 , Y10T428/24694
摘要： A colloid protected polyvinyl acetate emulsion resin can be employed as a corrugating adhesive. The use of this adhesive is useful for increasing the line speed for the manufacture of double and triple wall paperboard constructions.
摘要翻译：可以使用胶体保护的聚乙酸乙烯酯乳液树脂作为波纹粘合剂。使用这种粘合剂可用于增加生产双层和三层墙纸板结构的生产线速度。

4. 发明授权

US08037418B2 System and method for ensuring integrity of data-driven user interface of a wireless mobile station 失效
标题翻译：确保无线移动台的数据驱动用户界面的完整性的系统和方法
公开(公告)号：US08037418B2
公开(公告)日：2011-10-11
申请号：US10035800
申请日：2001-12-28
申请人： Sudhindra P. Herle , Mark Mitchell
发明人： Sudhindra P. Herle , Mark Mitchell
IPC分类号： G06F3/00
CPC分类号： H04M1/72525 , H04M1/72563
摘要： A wireless communication device stores a system GUI configuration file and a downloaded service provider GUI configuration file, each of which contains a text name checksum value that is calculated using the text names of the GUI parameter data stored either the system GUI configuration file or the service provider GUI configuration file. The text name checksum values are based on the text names of the GUI parameter data. After the download operation is complete, a text name checksum comparator program compares the downloaded text name checksum value to the initial text name checksum value in the system GUI configuration file. If the two text name checksum values do not match, the downloaded service provider GUI configuration file is rejected.
摘要翻译：无线通信装置存储系统GUI配置文件和下载的服务提供者GUI配置文件，每个文件包含使用存储在系统GUI配置文件或服务中的GUI参数数据的文本名称来计算的文本名称校验和值提供者GUI配置文件。文本名称校验和值基于GUI参数数据的文本名称。下载操作完成后，文本名称校验和比较程序将下载的文本名称校验和值与系统GUI配置文件中的初始文本名称校验和值进行比较。如果两个文本名称校验和值不匹配，则下载的服务提供商GUI配置文件将被拒绝。

5. 发明申请

US20070094237A1 Multiple active database systems 审中-公开
标题翻译：多个活动数据库系统
公开(公告)号：US20070094237A1
公开(公告)日：2007-04-26
申请号：US11638641
申请日：2006-12-13
申请人： Mark Mitchell , Thomas Fastner
发明人： Mark Mitchell , Thomas Fastner
IPC分类号： G06F17/30 , G06F7/00
CPC分类号： G06F16/275
摘要： Multiple-active database systems include at least two database systems that both store a common portion of a relational database. Each database system includes one or more data-storage facilities configured to store data forming the common portion of the relational database in one or more tables and one or more processing modules configured to manage access to the data in the data-storage facilities. One or more management components are configured to distribute database requests directed at the common portion of the relational database among the database systems and to synchronize the data across the database systems when changes are made to the data stored in at least one of the database systems.
摘要翻译：多活动数据库系统包括至少两个存储关系数据库的公共部分的数据库系统。每个数据库系统包括一个或多个数据存储设施，其被配置为将形成关系数据库的公共部分的数据存储在一个或多个表中，并且一个或多个处理模块被配置为管理对数据存储设施中的数据的访问。一个或多个管理组件被配置为分发针对数据库系统中的关系数据库的公共部分的数据库请求，并且当对存储在至少一个数据库系统中的数据进行改变时，跨数据库系统同步数据。

6. 发明申请

US20050154056A1 Inhibitors of HCV NS5B polymerase 失效
标题翻译： HCV NS5B聚合酶抑制剂
公开(公告)号：US20050154056A1
公开(公告)日：2005-07-14
申请号：US10981128
申请日：2004-11-03
申请人： Fan Yang , Bo Zhang , Nancy Wicnienski , Jeffrey Pfefferkorn , Meredith Greene , Ke Chen , Richard Nugent , Matthew Reding , Robert Kelly , Mark Mitchell , Lee Funk , Richard Heier , Rebecca Anderson
发明人： Fan Yang , Bo Zhang , Nancy Wicnienski , Jeffrey Pfefferkorn , Meredith Greene , Ke Chen , Richard Nugent , Matthew Reding , Robert Kelly , Mark Mitchell , Lee Funk , Richard Heier , Rebecca Anderson
IPC分类号： A61K31/255 , A61K31/335 , C07C251/86 , C07C309/67 , C07C309/73 , C07C309/74 , C07C309/75 , C07C309/77 , C07C311/21 , C07C311/49 , C07C317/28 , C07C317/32 , C07C317/44 , C07C323/62 , C07D207/277 , C07D207/337 , C07D209/18 , C07D213/56 , C07D213/61 , C07D213/65 , C07D213/71 , C07D213/75 , C07D213/81 , C07D213/82 , C07D231/12 , C07D231/18 , C07D233/28 , C07D233/64 , C07D263/32 , C07D277/32 , C07D285/14 , C07D307/24 , C07D307/54 , C07D307/79 , C07D317/60 , C07D333/24 , C07D333/34 , C07D409/04 , C07D413/04 , C07C39/46
CPC分类号： C07C251/86 , C07C309/67 , C07C309/73 , C07C309/74 , C07C309/75 , C07C309/77 , C07C311/21 , C07C311/49 , C07C317/28 , C07C317/32 , C07C317/44 , C07C323/62 , C07C2601/14 , C07C2602/42 , C07C2603/74 , C07D207/277 , C07D207/337 , C07D209/18 , C07D213/56 , C07D213/61 , C07D213/65 , C07D213/71 , C07D213/75 , C07D213/81 , C07D213/82 , C07D231/12 , C07D231/18 , C07D233/28 , C07D233/64 , C07D263/32 , C07D277/32 , C07D285/14 , C07D307/24 , C07D307/54 , C07D307/79 , C07D317/60 , C07D333/24 , C07D333/34 , C07D409/04 , C07D413/04
摘要： The present invention relates to compounds, process for their synthesis, compositions and methods for the treatment and prevention of hepatitis C virus (HCV) infection. In particular, the present invention provides novel compounds, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment or prevention of HCV infection. The present invention also provides processes and intermediates for the synthesis of these compounds.
摘要翻译：本发明涉及化合物，其合成方法，用于治疗和预防丙型肝炎病毒（HCV）感染的组合物和方法。特别地，本发明提供新型化合物，含有这些化合物的药物组合物和使用这些化合物治疗或预防HCV感染的方法。本发明还提供了合成这些化合物的方法和中间体。

7. 发明授权

US4811787A Method for reducing the permeability of underground strata during secondary recovery of oil 失效
标题翻译：降低二次回采期间地下层渗透性的方法
公开(公告)号：US4811787A
公开(公告)日：1989-03-14
申请号：US154467
申请日：1988-02-08
申请人： Martin Navratil , Jimmy P. Baytycky , Mojmir Sovak , Mark Mitchell
发明人： Martin Navratil , Jimmy P. Baytycky , Mojmir Sovak , Mark Mitchell
IPC分类号： C09K8/508 , C09K8/514 , E21B33/138 , E21B43/22
CPC分类号： C09K8/514 , C09K8/5086
摘要： The invention provides a method for the secondary recovery of oil from an oil-bearing stratum having a zone of high fluid permeability, in which this zone is plugged by introducing into the stratum a gelable solution comprising an alkaline material, a polyphenolic vegetable material such as mimosa tannin extract and formaldehyde, the last compound being present as free formaldehyde, paraformaldehyde, a phenol-formaldehyde resole, hexamethylenetetramine or urea-formaldehyde concentrate. The gelable solution has a pH of at least 9.5 and may optionally include a viscosifier. The gelable solutions are relatively insensitive to brines or temperature and gel to produce mechanically strong gels, even in the presence of oil-wet minerals. If desired, the alkaline material can be an alkali metal carbonate, and the use of such carbonates permits the permeability of the plugged high permeability zone to be adjusted after formation of the gel by treating the gel with acid.
摘要翻译：本发明提供了一种用于从具有高流体渗透性区域的含油层次级回收油的方法，其中该区域通过将包含碱性物质的可凝胶溶液，诸如含羞草单宁提取物和甲醛，最后一种化合物以游离甲醛，多聚甲醛，苯酚 - 甲醛甲阶酚醛，六亚甲基四胺或脲 - 甲醛浓缩物存在。胶凝溶液的pH值至少为9.5，并且可以任选地包括增粘剂。即使在存在油湿矿物的情况下，胶凝剂对盐水或温度和凝胶相对不敏感以产生机械强烈的凝胶。如果需要，碱性材料可以是碱金属碳酸盐，并且使用这种碳酸盐可以通过用酸处理凝胶来形成凝胶后调节堵塞的高渗透性区域的渗透性。

8. 发明申请

US20120006930A1 Artificial Turf Remover and Infill Separator, and Method of Use Thereof 失效
标题翻译：人造草坪除草剂和填料分离器及其使用方法
公开(公告)号：US20120006930A1
公开(公告)日：2012-01-12
申请号：US12832301
申请日：2010-07-08
申请人： Mark Mitchell
发明人： Mark Mitchell
IPC分类号： A63C19/00 , B65H18/08 , B65H23/04
CPC分类号： E01C13/08 , A63C19/12
摘要： An artificial turf remover and infill separator comprising an artificial turf removing station, an infill separating station and an artificial turf collection station. The infill separating station comprises rotatable spinning devices comprises corners, wherein each corner comprises chain links. The artificial turf remover and infill separator is utilized by positioning a strip of artificial turf on an angular ramp, conveying the artificial turf over a first pair of rotatable rollers, conveying the artificial turf between a second pair of rotatable rollers, separating infill from the artificial turf via fin-shaped picks, square-shaped rotatable diggers and the rotatable spinning devices, wherein the chain links jostle the infill material from the artificial turf onto a first and second infill collection conveyor belt. The artificial turf is then conveyed over a first and second base roller, between a rear pair of counter-rotating rollers and then wound around a final artificial turf collection roller.
摘要翻译：一种人造草坪去除器和填充分离器，包括人造草坪去除站，填充分离站和人造草坪收集站。填充分离站包括可旋转的旋转装置，包括角部，其中每个角包括链节。人造草皮去除器和填充分离器通过将人造草皮条定位在斜坡上，将人造草皮输送在第一对可旋转辊上，将人造草皮输送在第二对可旋转辊之间，将人造草皮从人工通过鳍形拾取器的草皮，方形可旋转挖掘机和可旋转的纺纱装置，其中链节将填充材料从人造草皮推送到第一和第二填充物收集传送带上。然后将人造草皮在第一和第二基底辊之间，在后面的一对反向旋转辊之间传送，然后缠绕在最终的人造草皮收集辊上。

9. 发明申请

US20080014050A1 Non-Circular Can End With Corner-Mounted Tab and Tooling and a Conversion Press for Providing Same 失效
标题翻译：非圆形可以带有角安装的标签和工具，并提供相同的转换按钮
公开(公告)号：US20080014050A1
公开(公告)日：2008-01-17
申请号：US11777698
申请日：2007-07-13
申请人： Gregory Butcher , Kenneth Fultz , Mark Mitchell , David Stradling , Greg Williams
发明人： Gregory Butcher , Kenneth Fultz , Mark Mitchell , David Stradling , Greg Williams
IPC分类号： B21D51/44
CPC分类号： B21D51/383
摘要： A non-circular can end for a container having walls which form an opening includes a corner-mounted pull tab opener secured to a severable panel portion by an integral rivet. The corner-mounted opener facilitates easy opening of the can end. A pair of generally parallel bead recesses on either side of the integral rivet stiffen the severable panel portion in order to facilitate bending of the panel aft of the rivet to easily open the can end. The severable panel optionally further includes a mustache-shaped scoreline to reduce the amount of force required to lift the opener. Tooling and a conversion press for converting shells into the non-circular can ends are also disclosed.
摘要翻译：具有形成开口的壁的容器的非圆形罐端部包括通过整体式铆钉固定到可分割板部分的拐角安装的拉片开启器。角安装的开启器有助于容易地打开罐头端部。一体式铆钉的任一侧上的一对大致平行的胎圈凹槽加强了可分割的面板部分，以便于铆钉的后面弯曲以容易地打开罐端部。可分开的面板可选地进一步包括胡须形刻痕，以减少抬起开启器所需的力量。还公开了用于将壳转换成非圆形罐端的模具和转换压力机。

10. 发明申请

US20070253815A1 Cooled gas turbine aerofoil 有权
标题翻译：冷气涡轮机翼
公开(公告)号：US20070253815A1
公开(公告)日：2007-11-01
申请号：US11207892
申请日：2005-08-22
申请人： Michiel Kopmels , Ian Tibbott , Edwin Dane , Mark Mitchell
发明人： Michiel Kopmels , Ian Tibbott , Edwin Dane , Mark Mitchell
IPC分类号： F01D5/18
CPC分类号： F01D5/188 , F01D5/18 , F01D5/186 , F01D5/20 , F01D5/225 , Y02T50/676
摘要： An internal fluid cooling system for a gas turbine aerofoil (2) comprises a plurality of multi-pass cooling arrangements each of which consists of a serpentine passage (50,52,54 & 48,56,58) in the interior of the aerofoil (2). The cooling fluid—in particular air—is supplied to an inlet end (22,24) of each passage (50,52,54 & 48,56,58) and exhausted through a multiplicity of discharge holes (60,62,64,68) to provide tip, leading edge, trailing edge and surface film cooling. The inlet end (22) of a first serpentine passage (50,52,54) is positioned close to the leading edge (26) and flows rearwards while the inlet end (24) of the second serpentine passage (48,56,58) is positioned close to the trailing edge (28) and flows forwards. These serpentine passages are disposed side-by-side, one adjacent the pressure surface (14) and the other adjacent the suction surface (16) on opposite sides of a main load carrying member (30) which comprises a major part of the internal structure (30,36,38,40,42,44) of the aerofoil (2).
摘要翻译：用于燃气轮机机翼（2）的内部流体冷却系统包括多个多通道冷却装置，每个多通道冷却装置由机翼内部的蛇形通道（50,52,54和48,56,58） 2）。冷却流体 - 特别是空气 - 被供应到每个通道（50,52,54和48,56,58）的入口端（22,24），并通过多个排放孔（60,62,64， 68）提供尖端，前缘，后缘和表面膜冷却。第一蛇形通道（50,52,54）的入口端（22）定位成靠近前缘（26）并向后流动，同时第二蛇形通道（48,56,58）的入口端（24）定位成靠近后缘（28）并向前流动。这些蛇形通道并排设置，一个邻近压力表面（14），另一个邻近主负载承载构件（30）的相对侧的吸附表面（16），该主负载承载构件（30）包括内部结构的主要部分（30,36,38,40,42,44）的机翼（2）。

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