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2. 发明申请

US20140254622A1 METHOD FOR VERIFYING A TEMPERATURE MEASUREMENT IN A MICRO-ENVIRONMENT AND SYSTEM FOR VERIFYING A TEMPERATURE MEASUREMENT IN A MICRO-ENVIRONMENT 有权
标题翻译：用于在微环境中验证温度测量的方法和用于在微环境中验证温度测量的系统
公开(公告)号：US20140254622A1
公开(公告)日：2014-09-11
申请号：US14352708
申请日：2012-10-22
申请人： QIAGEN INSTRUMENTS AG
发明人： Dirk Leber , Stephan Baehler , Hansueli Meyer
IPC分类号： G01K15/00
CPC分类号： G01K15/007 , G01K11/165 , G01K11/20 , G01K15/005
摘要： The present invention pertains to a method suitable for analysing the temperature control of a device which is supposed to establish a defined temperature in a micro-environment, said method comprising a first Optical Temperature Verification step which comprises a) providing one or more thermochromatic liquid crystals in a micro-environment, wherein each thermochromatic liquid crystal has a specific event temperature, b) providing one or more temperature dependent luminophores in a micro-environment, c) varying the temperature in the micro-environments and irradiating the micro-environments with light, d) recording the luminescence of the one or more temperature dependent luminophores when the event temperature of the one or more thermochromatic liquid crystals is reached in the micro-environment and wherein said method preferably comprises a second Optical Temperature Verification step, which comprises the following a) providing one or more temperature dependent luminophores that were used in the First Optical Temperature Verification in a micro-environment, b) varying the temperature of the micro-environments and irradiating the micro-environments with light, c) monitoring the luminescence emitted. The respective method is very suitable to analyse the temperature control of a thermal cycler, in particular during a calibration.
摘要翻译：本发明涉及一种适用于分析假定在微环境中建立限定温度的装置的温度控制的方法，所述方法包括第一光学温度验证步骤，该步骤包括：a）提供一个或多个热色液晶在微环境中，其中每个热色液晶具有特定的事件温度，b）在微环境中提供一个或多个与温度相关的发光体，c）改变微环境中的温度并用光照射微环境，d）当在所述微环境中达到所述一种或多种热色液晶的事件温度时记录所述一种或多种温度依赖性发光体的发光，并且其中所述方法优选地包括第二光学温度验证步骤，其包括以下 a）提供一个或多个依赖温度的发光体 e用于微环境中的第一光学温度验证，b）改变微环境的温度并用光照射微环境，c）监测发射的发光。相应的方法非常适合分析热循环仪的温度控制，特别是在校准过程中。

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