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    • 1. 发明授权
    • Process of making zirconium-aluminum antiperspirant active
    • 制备锆 - 铝止汗剂的工艺
    • US6136302A
    • 2000-10-24
    • US252385
    • 1999-02-18
    • Prem Sagar JunejaDavid Frederick Swaile
    • Prem Sagar JunejaDavid Frederick Swaile
    • C01G25/00A61K7/32A61K7/00A61K7/34A61K7/38
    • A61Q15/00A61K8/28C01G25/00
    • Disclosed is a process for making zirconium-aluminum salts for use as antiperspirant active, which process comprises the step of anhydrous mixing of a zirconium salt and an aluminum salt to form a zirconium-aluminum salt, wherein the mixture of zirconium and aluminum salts is substantially free of unbound water at all times during the process. The zirconium, aluminum and zirconium-aluminum salts in the process are in the form of particulate or other solids, or can otherwise be dissolved or dispersed in a non-aqueous medium. The process allows for the formation of zirconium-aluminum salts as antiperspirant active without relying upon prior art methods which teach that zirconium-aluminum salts require reaction together in an aqueous medium. This process is more stable than the prior art methods and provides better control over optimizing the polymer size distribution within the resulting zirconium-aluminum salts.
    • 公开了一种制备用作止汗活性物质的锆 - 铝盐的方法,该方法包括将锆盐和铝盐无水混合以形成锆 - 铝盐的步骤,其中锆和铝盐的混合物基本上是 在过程中始终没有未结合的水。 该方法中的锆,铝和锆 - 铝盐是颗粒或其它固体的形式,否则可以溶解或分散在非水介质中。 该方法允许形成锆 - 铝盐作为止汗活性物,而不依赖于现有技术的方法,该方法教导锆 - 铝盐需要在水性介质中一起反应。 该方法比现有技术方法更稳定,并且提供了对所得锆 - 铝盐内的聚合物尺寸分布优化的更好控制。