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    • 4. 发明申请
    • Apparatus and method for processing microscopic single cell biological specimens with a single microtool
    • 用单个微型工具处理微观单细胞生物标本的装置和方法
    • US20100174133A1
    • 2010-07-08
    • US12592630
    • 2009-11-30
    • Jacques CohenTim SchimmelMichael D. Cecchi
    • Jacques CohenTim SchimmelMichael D. Cecchi
    • A61B17/43A61B17/435
    • C12M21/06C12M23/10C12M23/34C12M33/04
    • An oocyte and embryo-positioning apparatus enables a plurality of oocytes, embryos or other cell specimens to be held and positioned for injection therein of fluid molecular reagents such as DNA, RNA, protein, cells, spermatozoa and cells; and removal of cells, fragments of cells, cytoplasm, nuclei and cellular organelles. The oocytes and embryos are kept separate from each other in open marked or unmarked well-compartments that are located in the culture container. Each well-compartment comprises one or more finger like structures that can position one oocyte or one embryo. The lanes between the digits of the fingers may be sloped allowing the oocytes or embryo to position at the narrowest and lowest point of the compartment. The method and oocytes and embryo-positioning apparatus of this invention includes a culturing container, such as a Petrie dish, in which the oocytes and embryos are held for micromanipulation. The Petrie dish preferably contains a plurality of the oocyte or embryo-holding finger like-structures which can be positioned in the Petrie dish in a predetermined pattern. For example, the well-compartments can be positioned in the Petrie dish as a strip of well-compartments between the 12 o'clock and 6 o'clock positions, or in any other planned deployment. Marked well-compartments can be identified by letters or numbers or symbols.
    • 卵母细胞和胚胎定位装置使多个卵母细胞,胚胎或其他细胞样品能够被保持和定位以便在其中注射流体分子试剂如DNA,RNA,蛋白质,细胞,精子和细胞; 去除细胞,细胞碎片,细胞质,细胞核和细胞器。 卵母细胞和胚胎在位于培养容器中的开放标记或未标记的良好隔室中彼此分开。 每个井室包括可以定位一个卵母细胞或一个胚胎的一个或多个手指状结构。 手指的数字之间的通道可以是倾斜的,允许卵母细胞或胚胎位于隔室的最窄和最低点处。 本发明的方法和卵母细胞和胚胎定位装置包括培养容器,例如培养皿,其中保持卵母细胞和胚胎用于显微操作。 培养皿优选含有多个可以预定图案定位在培养皿中的卵母细胞或胚胎保持手指状结构。 例如,隔间可以放置在Petrie盘中,作为12点和6点钟位置之间的隔间条,或任何其他计划的部署。 标记的隔间可以通过字母或数字或符号来标识。
    • 7. 发明授权
    • Automatic protection switch with visible disconnecting action and manual
resetting
    • 自动保护开关,具有可见的断开动作和手动复位
    • US4650937A
    • 1987-03-17
    • US666084
    • 1984-10-04
    • Elie BelbelChristian BlanchardJacques CohenAndre HauryMichel LauraireLuc Moreau
    • Elie BelbelChristian BlanchardJacques CohenAndre HauryMichel LauraireLuc Moreau
    • H01H73/36H01H20060101H01H71/60H01H15/18
    • H01H71/60
    • An electric switch apparatus for protecting an electric circuit, said apparatus comprising a case, a pivoting drawer connected to the case and adapted to be manually pivoted from a closed position to an open position and reversely, a switch having a fixed and a movable contact, the movable contact being mechanically linked to the drawer for simultaneous opening therewith and a breaking member for automatically breaking an electric circuit connected across two terminals of the case, the said breaking member operating in case of an overflow of current in the said circuit, the movable contact being able to be separated from the fixed contact under the action of an actuation member comprising a spring and a magnetizable member, said actuating member cooperating with a coil placed in the circuit and being reset during a manual opening and closing movement of the drawer.
    • PCT No.PCT / FR84 / 00024 Sec。 371日期1984年10月4日第 102(e)日期1984年10月4日PCT提交1984年2月3日PCT公布。 公开号WO84 / 03173 日本1984年8月16日。一种用于保护电路的电开关装置,所述装置包括壳体,连接到壳体的枢转抽屉,并且适于从关闭位置手动地枢转到打开位置,并且反向地具有开关, 固定和可动触点,所述可动触点机械地连接到所述抽屉以与其同时开启;以及断开构件,用于自动断开连接在所述壳体的两个端子上的电路,所述断开构件在电流溢出的情况下操作 在所述电路中,所述可动触头能够在包括弹簧和可磁化构件的致动构件的作用下与所述固定触点分离,所述致动构件与放置在所述电路中的线圈配合并且在手动开启期间被复位 并关闭抽屉的运动。