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    • 5. 发明授权
    • Modular, self-contained, mobile clean room
    • 模块化,独立,移动洁净室
    • US09518748B2
    • 2016-12-13
    • US12856888
    • 2010-08-16
    • R. Barry HoltzTroy ArledgePhillip B. MaplesDavid M. Shanahan
    • R. Barry HoltzTroy ArledgePhillip B. MaplesDavid M. Shanahan
    • B01L1/04F24F3/16C12M1/12
    • F24F3/16B01L1/04C12M37/00F24F3/161Y02A50/22Y10T29/49826
    • Biosafety units, methods of making, and sealing the same are disclosed herein. The units comprise at least one controlled air, sealable, sterilizable cleanroom; and a mechanical system room adjacent to the cleanroom comprising: at least two air handling units in a support room adjacent the cleanroom that provide redundant air to the cleanroom with at least Class 100,000 air purity, the air handling units connected to a one or more supply ducts to the cleanroom, and an exhaust duct in communication with the cleanroom and the air handling unit exhaust, wherein a pressure gradient is formed between the cleanroom and the exterior of the structure; and at least two power supplies that provide redundant power to electrical outlets in the cleanroom, wherein the at least two power supplies are connectable to one or more external power sources and the structure is pre-validatable or validated for pharmaceutical manufacturing.
    • 本文公开了生物安全单元,制造方法和密封方法。 这些单元包括至少一个受控的空气,可密封的可消毒洁净室; 以及与洁净室相邻的机械系统室,包括:在与洁净室相邻的支撑室中的至少两个空气处理单元,其向洁净室提供具有至少100,000级空气纯度的冗余空气,所述空气处理单元连接到一个或多个供应 与无尘室和空气处理单元排气连通的排气管,其中在洁净室和结构外部之间形成压力梯度; 以及至少两个电源,其为洁净室中的电源插座提供冗余电力,其中所述至少两个电源可连接到一个或多个外部电源,并且所述结构是预先验证的或用于药物制造的验证。
    • 9. 发明申请
    • Filter Unit
    • 过滤单元
    • US20150059299A1
    • 2015-03-05
    • US14536987
    • 2014-11-10
    • AIREX CO., LTD.
    • Koji KawasakiMinoru MiyamotoToshinaga Toda
    • F24F3/16
    • F24F3/1607B01D46/00B01D46/0091B01D46/0098B01D46/12B01L1/04B08B15/02B08B15/023B08B15/026B08B2215/003B25J21/02Y10S55/18
    • A filter unit which has a simple structure and can ensure high-level safety in response to risk during operation of an apparatus such as an isolator device is provided. One type of filter unit includes a rectangular cylindrical body having a first wall portion provided with an air inlet portion and a second wall portion formed so as to cross the first wall portion and provided with an air discharge port portion, a filter member provided in the cylindrical body for filtering introduced air, an annular seal member surrounding an outer periphery portion of the air inlet portion, and a detachable lid body closing the air inlet portion in an airtight manner. The filter unit is connected to a work chamber such that the air inlet portion is attached so as to oppose an air outlet of the work chamber and so that the seal member abuts an outer wall portion of the work chamber in an airtight manner.
    • 提供了具有简单结构并且可以确保在诸如隔离装置的装置的操作期间响应于风险的高级安全性的过滤器单元。 一种类型的过滤器单元包括矩形筒体,其具有设置有空气入口部分的第一壁部分和形成为跨过第一壁部分并且设置有排气口部分的第二壁部分, 用于过滤引入空气的圆筒体,围绕空气入口部分的外周部分的环形密封构件,以及以气密方式封闭空气入口部分的可拆卸盖体。 过滤器单元连接到工作室,使得空气入口部分被安装成与工作室的空气出口相对,并且密封构件以气密的方式邻接工作室的外壁部分。
    • 10. 发明申请
    • CLEAN ROOM CONTROL SYSTEM AND METHOD
    • 清洁室控制系统和方法
    • US20130324026A1
    • 2013-12-05
    • US13984642
    • 2012-02-16
    • John L. Fiorita, JR.
    • John L. Fiorita, JR.
    • F24F3/16F24F11/02B01L1/04
    • F24F3/161B01L1/04F24F11/72F24F11/77F24F2011/0004Y02B30/746
    • In a system and method of controlling particulate count in a clean room having a number of compartments/zones in series, in response to a first level of energy consumption by speed adjustable fans supplying a first volume of air per unit of time to the clean room, differential air pressures are established in the clean room compartment/zone-by-compartment/zone in series from a first compartment/zone which has a requirement for the highest air pressure to a last compartment/zone which has a requirement for the lowest air pressure. In response to a second level of energy consumption by the speed adjustable fans supplying a second volume of air per unit of time to the clean room, the same differential air pressures are substantially maintained in the clean room.
    • 在具有串联的多个隔间/区域的洁净室中的微粒计数的系统和方法中,响应于每单位时间向洁净室供应第一体积空气的速度可调节风扇的第一能量消耗水平 在洁净室隔室/隔间/区域中建立差分空气压力,从第一隔室/区域串联建立,该第一隔间/区域要求最高空气压力到最后一个隔间/区域,该最后隔室/区域需要最低空气 压力。 响应于通过每单位时间向洁净室供应第二体积的空气的速度可调风扇的能量消耗的第二水平,在洁净室中基本保持相同的差分空气压力。