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1. 发明授权

US07416558B2 Drug-eluting stent cover and method of use 有权
标题翻译：药物洗脱支架盖及使用方法
公开(公告)号：US07416558B2
公开(公告)日：2008-08-26
申请号：US11497706
申请日：2006-08-01
申请人： Philip S. Yip , James Jacobs , Syed Hossainy , Jon Becker , Timothy A. Limon
发明人： Philip S. Yip , James Jacobs , Syed Hossainy , Jon Becker , Timothy A. Limon
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/90 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/91575 , A61F2210/0076 , A61F2220/005 , A61F2250/0036 , A61F2250/0067 , A61F2250/0071 , Y10S623/903
摘要： An intravascular stent includes an eluting sheath fabricated from a mesh for controlled release of therapeutic drugs and for delivery of the therapeutic drugs in localized drug therapy in a blood vessel. The eluting sheath is attached to at least a portion of an outside surface area of the stent structure and is fabricated from a mesh designed to neck down in response to a radially outward directed force resulting in the uniform expansion of the stent. The eluting sheath can be loaded with at least one therapeutic drug for the release thereof at a treatment site to facilitate repair of a damaged vessel. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.
摘要翻译：血管内支架包括由用于控制释放治疗药物的网格和用于在血管中局部药物治疗中递送治疗药物的筛网制成的洗脱鞘。洗脱鞘附着到支架结构的外表面区域的至少一部分上，并且由设计成颈部向下的网眼制成，以适应径向向外的力，导致支架的均匀膨胀。洗脱鞘可以装载至少一种用于在治疗部位释放的治疗药物，以便于修复受损血管。支架在纵向具有高度的柔性，但具有足够的容器壁覆盖和径向强度足以保持打开动脉或其他体腔。

2. 发明授权

US07413574B2 Drug-eluting stent cover method of use 有权
标题翻译：药物洗脱支架覆盖法使用
公开(公告)号：US07413574B2
公开(公告)日：2008-08-19
申请号：US11497652
申请日：2006-08-01
申请人： Philip S. Yip , James Jacobs , Syed Hossainy , Jon Becker , Timothy A. Limon
发明人： Philip S. Yip , James Jacobs , Syed Hossainy , Jon Becker , Timothy A. Limon
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/90 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/91575 , A61F2210/0076 , A61F2220/005 , A61F2250/0036 , A61F2250/0067 , A61F2250/0071 , Y10S623/903
摘要： An intravascular stent includes an eluting sheath fabricated from a mesh for controlled release of therapeutic drugs and for delivery of the therapeutic drugs in localized drug therapy in a blood vessel. The eluting sheath is attached to at least a portion of an outside surface area of the stent structure and is fabricated from a mesh designed to neck down in response to a radially outward directed force resulting in the uniform expansion of the stent. The eluting sheath can be loaded with at least one therapeutic drug for the release thereof at a treatment site to facilitate repair of a damaged vessel. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.
摘要翻译：血管内支架包括由用于控制释放治疗药物的网格和用于在血管中局部药物治疗中递送治疗药物的筛网制成的洗脱鞘。洗脱鞘附着到支架结构的外表面区域的至少一部分上，并且由设计成颈部向下的网眼制成，以适应径向向外的力，导致支架的均匀膨胀。洗脱鞘可以装载至少一种用于在治疗部位释放的治疗药物，以便于修复受损血管。支架在纵向具有高度的柔性，但具有足够的容器壁覆盖和径向强度足以保持打开动脉或其他体腔。

3. 发明授权

US07105018B1 Drug-eluting stent cover and method of use 有权
公开(公告)号：US07105018B1
公开(公告)日：2006-09-12
申请号：US10334034
申请日：2002-12-30
申请人： Philip S. Yip , James Jacobs , Syed Hossainy , Jon Becker , Timothy A. Limon
发明人： Philip S. Yip , James Jacobs , Syed Hossainy , Jon Becker , Timothy A. Limon
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/90 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/91575 , A61F2210/0076 , A61F2220/005 , A61F2250/0036 , A61F2250/0067 , A61F2250/0071 , Y10S623/903
摘要： An intravascular stent includes an eluting sheath fabricated from a mesh for controlled release of therapeutic drugs and for delivery of the therapeutic drugs in localized drug therapy in a blood vessel. The eluting sheath is attached to at least a portion of an outside surface area of the stent structure and is fabricated from a mesh designed to neck down in response to a radially outward directed force resulting in the uniform expansion of the stent. The eluting sheath can be loaded with at least one therapeutic drug for the release thereof at a treatment site to facilitate repair of a damaged vessel. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.

4. 发明申请

US20060271165A1 Drug-eluting stent cover and method of use 有权
标题翻译：药物洗脱支架盖及使用方法
公开(公告)号：US20060271165A1
公开(公告)日：2006-11-30
申请号：US11497652
申请日：2006-08-01
申请人： Philip Yip , James Jacobs , Syed Hossainy , Jon Becker , Timothy Limon
发明人： Philip Yip , James Jacobs , Syed Hossainy , Jon Becker , Timothy Limon
IPC分类号： A61F2/90
CPC分类号： A61F2/91 , A61F2/90 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/91575 , A61F2210/0076 , A61F2220/005 , A61F2250/0036 , A61F2250/0067 , A61F2250/0071 , Y10S623/903
摘要： An intravascular stent includes an eluting sheath fabricated from a mesh for controlled release of therapeutic drugs and for delivery of the therapeutic drugs in localized drug therapy in a blood vessel. The eluting sheath is attached to at least a portion of an outside surface area of the stent structure and is fabricated from a mesh designed to neck down in response to a radially outward directed force resulting in the uniform expansion of the stent. The eluting sheath can be loaded with at least one therapeutic drug for the release thereof at a treatment site to facilitate repair of a damaged vessel. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.
摘要翻译：血管内支架包括由用于控制释放治疗药物的网格和用于在血管中局部药物治疗中递送治疗药物的筛网制成的洗脱鞘。洗脱鞘附着到支架结构的外表面区域的至少一部分上，并且由设计成颈部向下的网眼制成，以响应径向向外的力而导致支架的均匀膨胀。洗脱鞘可以装载至少一种用于在治疗部位释放的治疗药物，以便于修复受损血管。支架在纵向具有高度的柔性，但具有足够的容器壁覆盖和径向强度足以保持打开动脉或其他体腔。

5. 发明申请

US20070073383A1 Drug-eluting stent cover and method of use 有权
标题翻译：药物洗脱支架盖及使用方法
公开(公告)号：US20070073383A1
公开(公告)日：2007-03-29
申请号：US11497706
申请日：2006-08-01
申请人： Philip Yip , James Jacobs , Syed Hossainy , Jon Becker , Timothy Limon
发明人： Philip Yip , James Jacobs , Syed Hossainy , Jon Becker , Timothy Limon
IPC分类号： A61F2/90
CPC分类号： A61F2/91 , A61F2/90 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/91575 , A61F2210/0076 , A61F2220/005 , A61F2250/0036 , A61F2250/0067 , A61F2250/0071 , Y10S623/903
摘要： An intravascular stent includes an eluting sheath fabricated from a mesh for controlled release of therapeutic drugs and for delivery of the therapeutic drugs in localized drug therapy in a blood vessel. The eluting sheath is attached to at least a portion of an outside surface area of the stent structure and is fabricated from a mesh designed to neck down in response to a radially outward directed force resulting in the uniform expansion of the stent. The eluting sheath can be loaded with at least one therapeutic drug for the release thereof at a treatment site to facilitate repair of a damaged vessel. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen.
摘要翻译：血管内支架包括由用于控制释放治疗药物的网格和用于在血管中局部药物治疗中递送治疗药物的筛网制成的洗脱鞘。洗脱鞘附着到支架结构的外表面区域的至少一部分上，并且由设计成颈部向下的网眼制成，以适应径向向外的力，导致支架的均匀膨胀。洗脱鞘可以装载至少一种用于在治疗部位释放的治疗药物，以便于修复受损血管。支架在纵向具有高度的柔性，但具有足够的容器壁覆盖和径向强度足以保持打开动脉或其他体腔。

6. 发明申请

US20060043650A1 Methods for manufacturing a coated stent-balloon assembly 失效
标题翻译：涂覆的支架 - 球囊组件的制造方法
公开(公告)号：US20060043650A1
公开(公告)日：2006-03-02
申请号：US10928587
申请日：2004-08-26
申请人： Syed Hossainy , Srinivasan Sridharan , James Jacobs
发明人： Syed Hossainy , Srinivasan Sridharan , James Jacobs
IPC分类号： B28B1/00
CPC分类号： A61L31/08 , A61F2/958 , A61F2002/9522 , A61M25/1027 , A61M2025/1031 , Y10S606/908
摘要： Methods of coating a stent subsequent to mounting or crimping of the stent on a balloon of a catheter assembly are disclosed.
摘要翻译：公开了在将支架安装或压接在导管组件的球囊上之后涂覆支架的方法。

7. 发明授权

US07455646B2 Polymer coated guide wire 有权
标题翻译：聚合物涂层导丝
公开(公告)号：US07455646B2
公开(公告)日：2008-11-25
申请号：US11768794
申请日：2007-06-26
申请人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
发明人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
IPC分类号： A61B5/00 , A61M25/00
CPC分类号： A61M25/09 , A61L31/10 , A61L31/18 , A61M25/0045 , A61M25/0054 , A61M2025/09083 , A61M2025/09133 , A61M2025/09166
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under flouroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间歇的，连续的或以螺旋带的形式，用于在荧光成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

8. 发明申请

US20080113226A1 Energy storage device for loads having variable power rates 审中-公开
标题翻译：具有可变功率率的负载的储能装置
公开(公告)号：US20080113226A1
公开(公告)日：2008-05-15
申请号：US12010148
申请日：2008-01-22
申请人： Sankar Dasgupta , James Jacobs , Rakesh Bhola
发明人： Sankar Dasgupta , James Jacobs , Rakesh Bhola
IPC分类号： H01M16/00 , H01M10/44 , H02J7/00 , B60L11/18
CPC分类号： H02J7/0013 , B60L3/0046 , B60L7/12 , B60L50/16 , B60L50/52 , B60L53/14 , B60L58/12 , B60L58/15 , B60L58/20 , B60L58/26 , B60L2210/30 , B60L2240/545 , B60L2250/10 , Y02T10/646 , Y02T10/70 , Y02T10/7005 , Y02T10/7044 , Y02T10/7055 , Y02T10/7066 , Y02T10/7072 , Y02T10/7077 , Y02T10/7241 , Y02T90/127 , Y02T90/14
摘要： An electrical energy storage device for storing electrical energy and supplying the electrical energy to a driving motor at different power levels is disclosed. The electrical storage device has an energy battery connected to a power battery. The energy battery has a higher energy density than the power battery. However, the power battery can provide electrical power to the electrical motor at different power rates, thereby ensuring that the motor has sufficient power and current when needed. The power battery is continuously recharged by the energy storage battery. In this way, the power battery temporarily stores electrical energy received from the energy battery and provides the electrical energy at the different power rates as required by the motor. The energy storage device can be releasably connected to an external power source in order to recharge both batteries. Both batteries can be recharged independently to optimize the recharging and lifetime characteristics of the batteries.
摘要翻译：公开了一种用于存储电能并且以不同功率水平向驱动电动机供应电能的电能存储装置。电气存储装置具有连接到动力电池的能量电池。能量电池具有比动力电池更高的能量密度。然而，动力电池可以以不同的功率向电动机提供电力，从而确保电动机在需要时具有足够的功率和电流。动力电池由蓄能电池连续充电。以这种方式，动力电池临时存储从能量电池接收的电能并且以电动机所要求的不同功率提供电能。能量存储装置可以可释放地连接到外部电源，以便为两个电池充电。两个电池都可以独立充电，以优化电池的充电和使用寿命特性。

9. 发明申请

US20080042493A1 Battery controller and method for controlling a battery 审中-公开
标题翻译：电池控制器和控制电池的方法
公开(公告)号：US20080042493A1
公开(公告)日：2008-02-21
申请号：US11819400
申请日：2007-06-27
申请人： James Jacobs
发明人： James Jacobs
IPC分类号： H02J1/00
CPC分类号： H02J7/0018 , Y02T10/7055 , Y10T307/707
摘要： A battery controller for charging and discharging a plurality of batteries is disclosed. The battery controller has a plurality of direct current to direct current (DC to DC) converters connected to each other in series. Each battery of a plurality of batteries is electrically connectable to a respective DC to DC converter. A co-ordinator connected to each of the plurality of DC to DC converters controls charging and discharging of the battery electrically connected to the respective converter. The coordinator can also control charging and discharging of any one of the batteries to ensure that the battery retains sufficient electrical capacity, and, to increase the longevity of the respective batteries. Because each battery is electrically connected to a respective DC to DC converter, the energy from one battery can be used to charge another battery in order to monitor battery characteristics including energy capacity of each battery. Each of the DC to DC converters is selected to operate preferably below 30 volts while the total voltage of the entire battery system can be much more than 30 volts depending on the number of DC to DC converters placed in series.
摘要翻译：公开了一种用于对多个电池进行充电和放电的电池控制器。电池控制器具有多个直流到串联连接的直流（DC-DC）转换器。多个电池的每个电池可电连接到相应的DC-DC转换器。连接到多个DC至DC转换器中的每一个的协调器控制电连接到各个转换器的电池的充电和放电。协调器还可以控制任何一个电池的充电和放电，以确保电池保持足够的电容，并且增加各个电池的寿命。因为每个电池电连接到相应的DC到DC转换器，所以可以使用来自一个电池的能量来对另一个电池充电，以便监视包括每个电池的能量容量的电池特性。每个DC-DC转换器被选择为优选地低于30伏特，而整个电池系统的总电压可以远大于30伏，这取决于串联放置的DC-DC转换器的数量。

10. 发明申请

US20160000397A1 METHOD FOR ASSESSING STENOSIS SEVERITY THROUGH STENOSIS MAPPING 审中-公开
标题翻译：通过STENOSIS MAPPING评估STENOSIS严重程度的方法
公开(公告)号：US20160000397A1
公开(公告)日：2016-01-07
申请号：US14643024
申请日：2015-03-10
申请人： Zhongle Wu , James Jacobs
发明人： Zhongle Wu , James Jacobs
IPC分类号： A61B6/00 , A61B5/026 , A61B8/08 , A61B6/03
CPC分类号： A61B6/5217 , A61B5/0044 , A61B5/02007 , A61B5/02035 , A61B5/021 , A61B5/0263 , A61B5/1075 , A61B5/7282 , A61B6/032 , A61B6/504 , A61B6/5205 , A61B8/0891
摘要： A method of assessing stenosis severity for a patient includes obtaining patient information relevant to assessing severity of a stenosis, including anatomical imaging data of the patient. Based on the anatomical imaging data, the existence of any lesions of concerns may be identified. A three dimensional image can be generated of any irregular shaped lesion of concern and a surrounding area from the patient anatomical imaging data. A plurality of comparative two dimensional lesion specific models may be created that have conditions that correspond to the three dimensional model. The comparative two dimensional models may represent vessels having regular shaped lesions with each of the comparative two dimensional models represents a different stenosis severity. The three dimensional model can then be mapped to one of the plurality of comparative two dimensional models. After this mapping, a diagnosis of whether the patient has coronary artery disease may be made.
摘要翻译：评估患者狭窄严重程度的方法包括获得与评估狭窄程度相关的患者信息，包括患者的解剖成像数据。基于解剖成像数据，可以确定任何病症的存在。可以从患者的解剖学成像数据中产生所关注的任何不规则形状的病变和周围区域的三维图像。可以创建具有对应于三维模型的条件的多个对比二维损伤特定模型。比较二维模型可以代表具有规则形状损伤的血管，每个比较二维模型代表不同的狭窄严重程度。然后可以将三维模型映射到多个比较二维模型中的一个。在该映射之后，可以对患者是否患有冠状动脉疾病进行诊断。

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