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1. 发明申请

US20070160630A1 HEPATITIS-C VIRUS 4, 5 AND 6 失效
标题翻译： HEPATITIS-C VIRUS 4,5和6
公开(公告)号：US20070160630A1
公开(公告)日：2007-07-12
申请号：US11676842
申请日：2007-02-20
申请人： Peter Simmonds , Peng Yap , Ian Pike
发明人： Peter Simmonds , Peng Yap , Ian Pike
IPC分类号： C12Q1/68 , A61K39/12
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/29 , C12N2770/24222 , C12N2770/24234 , C12Q1/706 , C12Q1/707 , G01N33/56983 , G01N2333/18 , G01N2469/20 , Y10S436/811 , Y10S436/82 , Y10S436/825 , Y10S530/806 , Y10S530/811 , Y10S530/826
摘要： The present invention relates to a polynucleic acid composition comprising or consisting of at least one polynucleic acid containing 8 or more contiguous nucleotides corresponding to a nucleotide sequence from the region spanning positions 417 to 957 of the Core/E1 region of HCV type 3; and/or the region spanning positions 4664 to 4730 of the NS3 region of HCV type 3; and/or the region spanning positions 4892 to 5292 of the NS3/4 region of HCV type 3; and/or the region spanning positions 8023 to 8235 of the NS5 region of the BR36 subgroup of HCV type 3a; and/or the coding region of HCV type 4a starting at nucleotide 379 in the core region; and/or the coding region of HCV type 4; and/or the coding region of HCV type 5, with said nucleotide numbering being with respect to the numbering of HCV nucleic acids as shown in Table 1, and with said polynucleic acids containing at least one nucleotide difference with known HCV type 1, and/or HCV type 2 genomes in the above-indicated regions, or the complement thereof.
摘要翻译：本发明涉及包含至少一种含有8个或更多个连续核苷酸的多核苷酸的多核酸组合物，其对应于来自HCV 3型核心/ E1区域的位置417至957的区域的核苷酸序列; 和/或跨越HCV 3型NS3区域的位置4664至4730的区域; 和/或跨越HCV 3型NS3 / 4区的位置4892至5292的区域; 和/或跨越HCV3型BR36亚组的NS5区域的位置8023至8235的区域; 和/或从核心区域的核苷酸379开始的HCV型4a的编码区; 和/或HCV 4型的编码区; 和/或HCV 5型的编码区，其中所述核苷酸编号相对于表1所示的HCV核酸的编号，并且所述多核苷酸与已知的HCV I型具有至少一个核苷酸差异，和/ 或HCV 2型基因组，或其补体。

2. 发明申请

US20050221296A1 Hepatitis-C virus type 4, 5 and 6 有权
标题翻译：丙型肝炎病毒4型，5型和6型
公开(公告)号：US20050221296A1
公开(公告)日：2005-10-06
申请号：US11090952
申请日：2005-03-25
申请人： Peter Simmonds , Peng Yap , Ian Pike
发明人： Peter Simmonds , Peng Yap , Ian Pike
IPC分类号： G01N33/53 , A61K39/00 , A61K39/29 , A61P31/12 , C07K7/08 , C07K14/18 , C07K16/10 , C07K19/00 , C12N9/10 , C12N9/40 , C12N15/09 , C12N15/51 , C12P21/08 , C12Q1/68 , C12Q1/70 , G01N33/576 , C07K14/02
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/29 , C12N2770/24222 , C12N2770/24234 , C12Q1/706 , C12Q1/707 , G01N33/56983 , G01N2333/18 , G01N2469/20 , Y10S436/811 , Y10S436/82 , Y10S436/825 , Y10S530/806 , Y10S530/811 , Y10S530/826
摘要： The present invention relates to a polynucleic acid composition comprising or consisting of at least one polynucleic acid containing 8 or more contiguous nucleotides corresponding to a nucleotide sequence from the region spanning positions 417 to 957 of the Core/E1 region of HCV type 3; and/or the region spanning positions 4664 to 4730 of the NS3 region of HCV type 3; and/or the region spanning positions 4892 to 5292 of the NS3/4 region of HCV type 3; and/or the region spanning positions 8023 to 8235 of the NS5 region of the BR36 subgroup of HCV type 3a; and/or the coding region of HCV type 4a starting at nucleotide 379 in the core region; and/or the coding region of HCV type 4; and/or the coding region of HCV type 5, with said nucleotide numbering being with respect to the numbering of HCV nucleic acids as shown in Table 1, and with said polynucleic acids containing at least one nucleotide difference with known HCV type 1, and/or HCV type 2 genomes in the above-indicated regions, or the complement thereof.
摘要翻译：本发明涉及包含至少一种含有8个或更多个连续核苷酸的多核苷酸的多核酸组合物，其对应于来自HCV 3型核心/ E1区域的位置417至957的区域的核苷酸序列; 和/或跨越HCV 3型NS3区域的位置4664至4730的区域; 和/或跨越HCV 3型NS3 / 4区的位置4892至5292的区域; 和/或跨越HCV3型BR36亚组的NS5区域的位置8023至8235的区域; 和/或从核心区域的核苷酸379开始的HCV型4a的编码区; 和/或HCV 4型的编码区; 和/或HCV 5型的编码区，其中所述核苷酸编号相对于表1所示的HCV核酸的编号，并且所述多核苷酸与已知的HCV I型具有至少一个核苷酸差异，和/ 或上述区域中的HCV 2型HCV基因组，或其补体。

3. 发明申请

US20070128221A1 Hepatitis-C virus testing 失效
公开(公告)号：US20070128221A1
公开(公告)日：2007-06-07
申请号：US11652862
申请日：2007-01-12
申请人： Peter Simmonds , Shui-Wan Chan , Peng Yap
发明人： Peter Simmonds , Shui-Wan Chan , Peng Yap
IPC分类号： A61K39/395 , A61K39/12
CPC分类号： C07K14/005 , A61K39/00 , C07K16/109 , C07K2319/00 , C12N2770/24222 , C12Q1/707 , G01N33/56983 , G01N2333/18 , G01N2333/186 , Y10S436/82
摘要： New styles of hepatitis C virus (HCV), referred to as HCV-3 and HCV-4, have been identified and sequenced. Antigenic regions of HCV-2, HCV-3 and HCV-4 polypeptides have been identified. Immunoassays for HCV and antibodies thereto are described, which allow more complete screening of blood samples for HCV, and allow HCV genotyping.

4. 发明授权

US07198892B2 Hepatitis-C virus type 4, 5 and 6 有权
标题翻译：丙型肝炎病毒4型，5型和6型
公开(公告)号：US07198892B2
公开(公告)日：2007-04-03
申请号：US11090952
申请日：2005-03-25
申请人： Peter Simmonds , Peng Lee Yap , Ian Hugo Pike
发明人： Peter Simmonds , Peng Lee Yap , Ian Hugo Pike
IPC分类号： C12Q1/00 , C12Q1/70 , G01N33/53 , C07K7/00 , C07K17/00 , A61K38/00 , A61K39/00
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/29 , C12N2770/24222 , C12N2770/24234 , C12Q1/706 , C12Q1/707 , G01N33/56983 , G01N2333/18 , G01N2469/20 , Y10S436/811 , Y10S436/82 , Y10S436/825 , Y10S530/806 , Y10S530/811 , Y10S530/826
摘要： The present invention relates to a polynucleic acid composition comprising or consisting of at least one polynucleic acid containing 8 or more contiguous nucleotides corresponding to a nucleotide sequence from the region spanning positions 417 to 957 of the Core/E1 region of HCV type 3; and/or the region spanning positions 4664 to 4730 of the NS3 region of HCV type 3; and/or the region spanning positions 4892 to 5292 of the NS3/4 region of HCV type 3; and/or the region spanning positions 8023 to 8235 of the NS5 region of the BR36 subgroup of HCV type 3a; and/or the coding region of HCV type 4a starting at nucleotide 379 in the core region; and/or the coding region of HCV type 4; and/or the coding region of HCV type 5, with said nucleotide numbering being with respect to the numbering of HCV nucleic acids as shown in Table 1, and with said polynucleic acids containing at least one nucleotide difference with known HCV type 1, and/or HCV type 2 genomes in the above-indicated regions, or the complement thereof.
摘要翻译：本发明涉及包含至少一种含有8个或更多个连续核苷酸的多核苷酸的多核酸组合物，其对应于来自HCV 3型核心/ E1区域的位置417至957的区域的核苷酸序列; 和/或跨越HCV 3型NS3区域的位置4664至4730的区域; 和/或跨越HCV 3型NS3 / 4区的位置4892至5292的区域; 和/或跨越HCV3型BR36亚组的NS5区域的位置8023至8235的区域; 和/或从核心区域的核苷酸379开始的HCV型4a的编码区; 和/或HCV 4型的编码区; 和/或HCV 5型的编码区，其中所述核苷酸编号相对于表1所示的HCV核酸的编号，并且所述多核苷酸与已知的HCV I型具有至少一个核苷酸差异，和/ 或HCV 2型基因组，或其补体。

5. 发明授权

US07179470B2 Hepatitis-C virus testing 失效
标题翻译：丙型肝炎病毒检测
公开(公告)号：US07179470B2
公开(公告)日：2007-02-20
申请号：US10396964
申请日：2003-03-25
申请人： Peter Simmonds , Shui-Wan Chan , Peng Lee Yap
发明人： Peter Simmonds , Shui-Wan Chan , Peng Lee Yap
IPC分类号： G01N33/53 , A61K38/00
CPC分类号： C07K14/005 , A61K39/00 , C07K16/109 , C07K2319/00 , C12N2770/24222 , C12Q1/707 , G01N33/56983 , G01N2333/18 , G01N2333/186 , Y10S436/82
摘要： New styles of hepatitis C virus (HCV), referred to as HCV-3 and HCV-4, have been identified and sequenced. Antigenic regions of HCV-2, HCV-3 and HCV-4 polypeptides have been identified. Immunoassays for HCV and antibodies thereto are described, which allow more complete screening of blood samples for HCV, and allow HCV genotyping.
摘要翻译：已经鉴定并测序了新型的丙型肝炎病毒（HCV），称为HCV-3和HCV-4。已经鉴定了HCV-2，HCV-3和HCV-4多肽的抗原性区域。描述了HCV的免疫测定及其抗体，其允许对HCV的血液样品进行更全面的筛选，并且允许进行HCV基因分型。

6. 发明授权

US08318421B2 Hepatitis-C virus testing 失效
标题翻译：丙型肝炎病毒检测
公开(公告)号：US08318421B2
公开(公告)日：2012-11-27
申请号：US13180082
申请日：2011-07-11
申请人： Peter Simmonds , Shiu-Wan Chan , Peng Lee Yap
发明人： Peter Simmonds , Shiu-Wan Chan , Peng Lee Yap
IPC分类号： C12Q1/70 , C12Q1/68 , C12P19/34 , C07H21/04
CPC分类号： C07K14/005 , A61K39/00 , C07K16/109 , C07K2319/00 , C12N2770/24222 , C12Q1/707 , G01N33/56983 , G01N2333/18 , G01N2333/186 , Y10S436/82
摘要： New styles of hepatitis C virus (HCV), referred to as HCV-3 and HCV-4, have been identified and sequenced. Antigenic regions of HCV-2, HCV-3 and HCV-4 polypeptides have been identified. Immunoassays for HCV and antibodies thereto are described, which allow more complete screening of blood samples for HCV, and allow HCV genotyping.
摘要翻译：已经鉴定并测序了新型的丙型肝炎病毒（HCV），称为HCV-3和HCV-4。已经鉴定了HCV-2，HCV-3和HCV-4多肽的抗原性区域。描述了HCV的免疫测定及其抗体，其允许对HCV的血液样品进行更全面的筛选，并且允许进行HCV基因分型。

7. 发明申请

US20110287410A1 HEPATITIS-C VIRUS TESTING 失效
标题翻译： HEPATITIS-C病毒检测
公开(公告)号：US20110287410A1
公开(公告)日：2011-11-24
申请号：US13180082
申请日：2011-07-11
申请人： Peter Simmonds , Shiu-Wan Chan , Peng Lee Yap
发明人： Peter Simmonds , Shiu-Wan Chan , Peng Lee Yap
IPC分类号： C12Q1/70
CPC分类号： C07K14/005 , A61K39/00 , C07K16/109 , C07K2319/00 , C12N2770/24222 , C12Q1/707 , G01N33/56983 , G01N2333/18 , G01N2333/186 , Y10S436/82
摘要： New styles of hepatitis C virus (HCV), referred to as HCV-3 and HCV-4, have been identified and sequenced. Antigenic regions of HCV-2, HCV-3 and HCV-4 polypeptides have been identified. Immunoassays for HCV and antibodies thereto are described, which allow more complete screening of blood samples for HCV, and allow HCV genotyping.
摘要翻译：已经鉴定并测序了新型的丙型肝炎病毒（HCV），称为HCV-3和HCV-4。已经鉴定了HCV-2，HCV-3和HCV-4多肽的抗原性区域。描述了HCV的免疫测定及其抗体，其允许对HCV的血液样品进行更全面的筛选，并且允许进行HCV基因分型。

8. 发明授权

US07728121B2 Hepatitis-C virus type 4, 5 and 6 失效
标题翻译：丙型肝炎病毒4型，5型和6型
公开(公告)号：US07728121B2
公开(公告)日：2010-06-01
申请号：US11933672
申请日：2007-11-01
申请人： Peter Simmonds , Peng Lee Yap , Ian Hugo Pike
发明人： Peter Simmonds , Peng Lee Yap , Ian Hugo Pike
IPC分类号： C07H21/00 , A61K39/38 , A61K39/29
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/29 , C12N2770/24222 , C12N2770/24234 , C12Q1/706 , C12Q1/707 , G01N33/56983 , G01N2333/18 , G01N2469/20 , Y10S436/811 , Y10S436/82 , Y10S436/825 , Y10S530/806 , Y10S530/811 , Y10S530/826
摘要： The present invention relates to a polynucleic acid composition comprising or consisting of at least one polynucleic acid containing 8 or more contiguous nucleotides corresponding to a nucleotide sequence from the region spanning positions 417 to 957 of the Core/E1 region of HCV type 3; and/or the region spanning positions 4664 to 4730 of the NS3 region of HCV type 3; and/or the region spanning positions 4892 to 5292 of the NS3/4 region of HCV type 3; and/or the region spanning positions 8023 to 8235 of the NS5 region of the BR36 subgroup of HCV type 3a; and/or the coding region of HCV type 4a starting at nucleotide 379 in the core region; and/or the coding region of HCV type 4; and/or the coding region of HCV type 5, with said nucleotide numbering being with respect to the numbering of HCV nucleic acids as shown in Table 1, and with said polynucleic acids containing at least one nucleotide difference with known HCV type 1, and/or HCV type 2 genomes in the above-indicated regions, or the complement thereof.
摘要翻译：本发明涉及包含至少一种含有8个或更多个连续核苷酸的多核苷酸的多核酸组合物，其对应于来自HCV 3型核心/ E1区域的位置417至957的区域的核苷酸序列; 和/或跨越HCV 3型NS3区域的位置4664至4730的区域; 和/或跨越HCV 3型NS3 / 4区的位置4892至5292的区域; 和/或跨越HCV3型BR36亚组的NS5区域的位置8023至8235的区域; 和/或从核心区域的核苷酸379开始的HCV型4a的编码区; 和/或HCV 4型的编码区; 和/或HCV 5型的编码区，其中所述核苷酸编号相对于表1所示的HCV核酸的编号，并且所述多核苷酸与已知的HCV I型具有至少一个核苷酸差异，和/ 或上述区域中的HCV 2型HCV基因组，或其补体。

9. 发明授权

US07976849B2 Hepatitis-C virus testing 失效
标题翻译：丙型肝炎病毒检测
公开(公告)号：US07976849B2
公开(公告)日：2011-07-12
申请号：US12728030
申请日：2010-03-19
申请人： Peter Simmonds , Shui-Wan Chan , Peng Lee Yap
发明人： Peter Simmonds , Shui-Wan Chan , Peng Lee Yap
IPC分类号： G01N33/53 , A61K38/00
CPC分类号： C07K14/005 , A61K39/00 , C07K16/109 , C07K2319/00 , C12N2770/24222 , C12Q1/707 , G01N33/56983 , G01N2333/18 , G01N2333/186 , Y10S436/82
摘要： New styles of hepatitis C virus (HCV), referred to as HCV-3 and HCV-4, have been identified and sequenced. Antigenic regions of HCV-2, HCV-3 and HCV-4 polypeptides have been identified. Immunoassays for HCV and antibodies thereto are described, which allow more complete screening of blood samples for HCV, and allow HCV genotyping.
摘要翻译：已经鉴定并测序了新型的丙型肝炎病毒（HCV），称为HCV-3和HCV-4。已经鉴定了HCV-2，HCV-3和HCV-4多肽的抗原性区域。描述了HCV的免疫测定及其抗体，其允许对HCV的血液样品进行更全面的筛选，并且允许进行HCV基因分型。

10. 发明申请

US20100266624A1 HEPATITIS-C VIRUS TESTING 失效
标题翻译： HEPATITIS-C病毒检测
公开(公告)号：US20100266624A1
公开(公告)日：2010-10-21
申请号：US12728030
申请日：2010-03-19
申请人： Peter Simmonds , Shiu-Wan Chan , Peng Lee Yap
发明人： Peter Simmonds , Shiu-Wan Chan , Peng Lee Yap
IPC分类号： A61K39/29 , C07K14/00 , G01N33/53 , C12M1/34 , A61P37/04 , C12N9/38 , A61P31/14
CPC分类号： C07K14/005 , A61K39/00 , C07K16/109 , C07K2319/00 , C12N2770/24222 , C12Q1/707 , G01N33/56983 , G01N2333/18 , G01N2333/186 , Y10S436/82
摘要： New styles of hepatitis C virus (HCV), referred to as HCV-3 and HCV-4, have been identified and sequenced. Antigenic regions of HCV-2, HCV-3 and HCV-4 polypeptides have been identified. Immunoassays for HCV and antibodies thereto are described, which allow more complete screening of blood samples for HCV, and allow HCV genotyping.
摘要翻译：已经鉴定并测序了新型的丙型肝炎病毒（HCV），称为HCV-3和HCV-4。已经鉴定了HCV-2，HCV-3和HCV-4多肽的抗原性区域。描述了HCV的免疫测定及其抗体，其允许对HCV的血液样品进行更全面的筛选，并且允许进行HCV基因分型。

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